Archives
Viewpoint: The Evolution of Patient Diagnosis
5 Nov, 2017 | 19:18h | UTCThe Evolution of Patient Diagnosis: From Art to Digital Data-Driven Science – JAMA (free)
Fri, November 3 – 10 Stories of The Day!
3 Nov, 2017 | 02:08h | UTC
1 – Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Small Trial Raises Big Concerns That PCI In Stable Angina Is Just A Placebo – Cardiobrief (free) AND Diving Deep Into The ORBITA Trial – Cardiobrief (free) AND ‘Unbelievable’: Heart Stents Fail to Ease Chest Pain – The New York Times (10 articles per month are free) AND ORBITA: PCI Offers No Symptom Improvement Over Sham Procedure – TCTMD (free)
2 – Balanced Crystalloids vs Saline for Critically Ill Adults – American College of Chest Physicians Annual Meeting (free abstract)
Related Study: Balanced Crystalloids vs Saline for Noncritically Ill Adults in the Emergency Department – American College of Chest Physicians Annual Meeting (free abstract)
Commentaries: Landmark Trials Deliver Evidence to Rethink Saline Use – Medscape (free registration required) AND Saline on the Ropes? Studies find balanced crystalloid fluids safer – MedPage Today (free registration required)
3 – Familial hypercholesterolaemia: identification and management – NICE Guideline (free)
News release: Inherited risk of high cholesterol should be identified and treated as early as possible, NICE says in updated guidance (free)
Commentary: Intracranial Hemorrhage After Stroke Thrombolysis: More Questions Than Answers (free)
Top Ten Things to Know: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke (free PDF)
Slide Set: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in AIS (free PDF)
Related AHA/ASA Guidelines: Guidelines for the Early Management of Patients With Acute Ischemic Stroke (free) AND Guidelines for the Management of Spontaneous Intracerebral Hemorrhage (free)
Commentaries: Reducing the global cancer burden among young adults – The Lancet Oncology (free) AND Global burden of cancer among young adults aged 20–39 years – eCancer News (free) AND Cancer in Young Adults Disproportionately Affects Women – Medical Research (free)
6 – A ‘smart’ approach to performance drugs – ACP Internist (free)
Related: Growing use of smart drugs by students could be a recipe for disaster – The Conversation (free) AND Brain Hackers Seeking Peak Performance Use Risky Chemical Cocktails: “Smart drugs” are not clinically proven and could be dangerous – Scientific American (free) AND Universities must do more to tackle use of smart drugs, say experts – The Guardian (free) AND Tweaking brains with ‘smart drugs’ to get ahead in Silicon Valley – The Washington Post (free) AND Professors take same ‘smart drugs’ as students to keep up with workloads, claims academic – Independent (free)
7 – Opinion: Drug company sales reps should be banned from hospitals – STAT (free)
9 – Untreatable Gonorrhea Is Rapidly Spreading. Here’s What You Need to Know – TIME Health (free)
News release: Teen childbirth linked to increased risk for heart disease (free)
Commentaries: Teen childbirth linked to increased cardiovascular risk decades later – Cardiovascular Business (free) AND Study finds link between increased cardiovascular diseases and teen childbirth – News Medical (free)
Wed, November 1 – 10 Stories of The Day!
1 Nov, 2017 | 00:01h | UTC
1 – Lancet Countdown: Traking Progress on Health and Climate Change (free infographics, video and other resources)
Report: The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health (free registration required)
Commentaries: Health impacts of climate change already felt today – Imperial College London (free) AND How Climate Change Is Already Affecting Health, Spreading Disease – NPR Goats and Soda (free) AND Climate change already bringing disease, air pollution and heatwaves – The Guardian (free) AND Climate change isn’t just hurting the planet – it’s a public health emergency – The Guardian (free)
2 – Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text)
Commentaries: Acid reflux drug linked to more than doubled risk of stomach cancer – study – The Guardian (free) AND Gastric Cancer Risk Doubled With Long-term PPI Use – Medscape (free registration required) AND PPI Use After H. pylori Eradication Therapy Tied to Increased Risk for Gastric Cancer – Physician’s First Watch (free)
“Among 797 067 individuals on maintenance PPI therapy, the SIR of gastric cancer was over threefold increased (SIR=3.38, 95% CI 3.23 to 3.53)”.
4 – Review: Point of Care Ultrasound: An Overview – American College of Cardiology, Latest in Cardiology (free)
Related reviews: Ultrasonography in the emergency department – Critical Care (free) AND Clinically integrated multi-organ point-of-care ultrasound for undifferentiated respiratory difficulty, chest pain, or shock: a critical analytic review – Journal of Intensive Care (free) AND Common pitfalls in point-of-care ultrasound: a practical guide for emergency and critical care physicians – Critical Ultrasound Journal (free) AND Point-of-Care Ultrasonography by Pediatric Emergency Medicine Physicians – Pediatrics (free)
5 – 25th UEG (United European Gastroenterology) Week: Long-term aspirin use reduces the incidence of digestive cancers by up to 47% (free)
Commentaries: Long-Term Aspirin Use May Reduce Cancer Risk, Study Finds – Forbes (free) AND Aspirin slashes risk of gastrointestinal cancer – Medical News Today (free)
7 – Mefloquine for preventing malaria during travel to endemic areas – Cochrane Library (free)
News release: Can mefloquine prevent malaria during travel to areas where the disease is widespread? (free)
Commentary: Cochrane review provides clarity about safety of mefloquine for preventing malaria in travelers – News Medical (free)
Commentary: Can spicy foods curb salt cravings or lower blood pressure? – Reuters (free) AND Need to cut down on salt? Try something spicy instead – Medical News Today (free)
9 – Economic impact of palliative care among elderly cancer patients – presented at: 2017 Palliative and Supportive Care in Oncology Symposium (free abstract)
Commentaries: Palliative Care Associated With Decreased Costs For Patients With Advanced Cancer – Oncology Nurse Advisor (free) AND Early Palliative Care Is Key Driver in Reducing Costs – Medscape (free registration required)
Related study: Effect of Palliative Care on Aggressiveness of End-of-Life Care Among Patients With Advanced Cancer – Journal of Oncology Practice (link to abstract – $ for full-text) AND Commentaries: Palliative Care May Substantially Decrease Health-Care Utilization in Patients With Advanced Cancer – ASCO Post (free) AND End-of-Life Palliative Care Lowered Utilization for Patients With Cancer – AJMC (free)
Related guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free)
See also other recent CHEST guidelines on the management of cough in specific populations: Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold – CHEST Expert Panel Report (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough: CHEST Guideline and Expert Panel Report (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis: CHEST Guideline and Expert Panel Report (free)
Research: Daytime variation of perioperative myocardial injury in cardiac surgery
5 Nov, 2017 | 19:15h | UTCDaytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study – The Lancet (link to abstract – $ for full-text)
Commentaries: Why Heart Surgery May be Better in the Afternoon – Scientific American (free) AND Afternoon heart surgery has lower risk of complications, study suggests – The Guardian (free) AND Aortic Valve Replacement: Afternoon Surgery Linked to Fewer Adverse Events – Physician’s First Watch (free)
Review: Acute Management of Pulmonary Embolism
5 Nov, 2017 | 19:17h | UTCAcute Management of Pulmonary Embolism – American College of Cardiology, Latest in Cardiology (free)
Thu, November 2 – 10 Stories of The Day!
2 Nov, 2017 | 01:08h | UTC
2 – The Care of Children With Congenital Heart Disease in Their Primary Medical Home – Pediatrics (free)
3 – Glaucoma: diagnosis and management – NICE Guideline (free)
News release: People at a low risk of developing glaucoma can avoid unnecessary referral, says NICE (free)
4 – Overdiagnosis and disease labels: the case of polycystic ovary syndrome – STAT (free)
Related: Are expanding disease definitions unnecessarily labelling women with polycystic ovary syndrome? – The BMJ (link to summary – $ for full-text)
5 – Bacteria Can Evolve Resistance to Drugs Before Those Drugs Are Used – The Atlantic (free)
6 – What I’ve learned from 547 doctor suicides – Pamela Wible, via KevinMd.com (free)
Original article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)
9 – Aspirin reduces a woman’s chance of developing pre-eclampsia in pregnancy – NIHR Signal (free)
Original article: Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia – New England Journal of Medicine (link to abstract – $ for full-text)
10 – Vaginal cleansing before caesarean delivery reduces risk of infections – NIHR signal (free)
Original article: Vaginal Cleansing Before Cesarean Delivery: A Systematic Review and Meta-analysis – Obstetrics & Gynecology (link to abstract – $ for full-text)
Mon, October 30 – 10 Stories of The Day!
30 Oct, 2017 | 01:22h | UTC
1 – Book: Injury Prevention and Environmental Health – Disease Control Priorities, Third Edition (free)
Press Release: Disease Control Priorities, 3rd Edition Launches Volume on Injury Prevention & Environmental Health (free)
Previous volumes: 1 – Essential Surgery / 2 – Reproductive, Maternal, Newborn, and Child Health / 3 – Cancer / 4 – Mental, Neurological, and Substance Use Disorders
2 – NICE Guideline: Sinusitis (acute): antimicrobial prescribing (free)
News release: Antibiotics should not be used to treat the majority of sinus infections, NICE says (free)
3 – NICE Guideline: Cystic fibrosis: diagnosis and management (free)
News release: People with cystic fibrosis could be monitored through phone or video messaging, says NICE (free)
4 – NICE Guideline: Cataracts in adults: management (free)
News release: Take a patient-centred approach to treating cataracts, says NICE (free)
See also: Summary of KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors (free)
News release: KDIGO Guidelines on Living Kidney Donors: A Call for A Paradigm Shift (free)
Commentaries: The More Lavish the Gifts to Doctors, the Costlier the Drugs They Prescribe – The New York Times (10 articles per month are free) AND Study finds even small gifts from pharma companies change prescribing habits – FierceHealthcare (free) AND Pharma gifts to providers result in more branded, expensive prescriptions – Georgetown University Medical Center, via EurekAlert (free)
7 – Why we need better evidence – Centre for Evidence-Based Medicine, University of Oxford (free)
“20 fundamental problems with the production of evidence” (RT @CochraneUK see Tweet)
8 – Viewpoint: The Evolution of Patient Diagnosis: From Art to Digital Data-Driven Science – JAMA (free)
9 – Review: Acute Management of Pulmonary Embolism – American College of Cardiology, Latest in Cardiology (free)
10 – Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study – The Lancet (link to abstract – $ for full-text)
Commentaries: Why Heart Surgery May be Better in the Afternoon – Scientific American (free) AND Afternoon heart surgery has lower risk of complications, study suggests – The Guardian (free) AND Aortic Valve Replacement: Afternoon Surgery Linked to Fewer Adverse Events – Physician’s First Watch (free)
Tue, October 31 – 10 Stories of The Day!
31 Oct, 2017 | 00:51h | UTC
1 – Global tuberculosis report 2017 – World Health Organization (free PDF)
News release: WHO report signals urgent need for greater political commitment to end tuberculosis (free)
Commentaries: Tuberculosis world’s top infectious killer; UN health agency calls for political action to stop spread – UN News Center (free) AND Pandemic alert: Tuberculosis is world’s No. 1 infectious killer – CNBC (free) Despite progress, WHO paints ‘grim’ picture of global TB – CIDRAP (free)
News release: Societies Detail Treatment for Patients With Ventricular Arrhythmias (free)
See also: Executive summary (free PDF) AND Top Ten Things to Know (free PDF) AND Slide Set (free PDF)
Editorial: Back to the Future in Cardiogenic Shock — Initial PCI of the Culprit Lesion Only (free)
Commentaries: CULPRIT-SHOCK Disputes Benefit of Immediate Multivessel PCI in Patients With Cardiogenic Shock – TCTMD (free) AND CULPRIT-SHOCK: Culprit Lesion Only PCI Vs. Immediate Multivessel PCI in Cardiogenic Shock – American College of Cardiology, Latest in Cardiology (free)
4 – Prenatal Exposure to Acetaminophen and Risk of ADHD – Pediatrics (free)
Commentaries: An Association Between Prenatal Acetaminophen Use and ADHD: The Benefits of Large Data Sets – Pediatrics (free) AND Long-term Acetaminophen Use in Pregnancy and ADHD – 2 Minute Medicine (free) AND Study links acetaminophen in pregnancy to ADHD, but experts question results – CNN (free)
5 – Policy Statement: Cord Blood Banking for Potential Future Transplantation – American Academy of Pediatrics (free)
News release: Updated policy reaffirms value of public over private cord blood banks (free)
Commentaries: Pediatrics Group Updates Recommendations on Cord Blood Banking – Physician’s First Watch (free)
6 – Duration of Breastfeeding and Risk of SIDS: An Individual Participant Data Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Commentary: Breastfeeding for two months halves risk of SIDS – University of Virginia Health System, via ScienceDaily (free)
7 – Is there a conflict of interest behind your cancer diagnosis? – STAT (free)
8 – Richard Lehman’s journal reviews, 30 October 2017 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Commentary: E-cigarette use by high school students linked to cigarette smoking – ScienceDaily (free)
10 – Review: So you think it is sepsis: considerations beyond lung and urine in the sick patient without a source – emDocs (free)
Systematic review: antibiotics for preventing pneumococcal infection in children with sickle cell disease
29 Oct, 2017 | 01:37h | UTCOriginal article: Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease – Cochrane Library (link to abstract – $ for full-text)
Source: EvidenceAlerts
Guideline: Responding to children and adolescents who have been sexually abused
29 Oct, 2017 | 01:40h | UTCResponding to children and adolescents who have been sexually abused – World Health Organization (free)
News release: Responding to children and adolescents who have been sexually abused (free)
World leaders rehearse for a pandemic that will come ‘sooner than we expect’
29 Oct, 2017 | 01:38h | UTCWorld leaders rehearse for a pandemic that will come ‘sooner than we expect’ – The Washington Post (free)
Guideline: Screening for Lung Cancer
29 Oct, 2017 | 01:32h | UTCNews release: American College of Chest Physicians unveils new lung cancer screening guidelines at CHEST 2017 (free)
Perspective: HIV Drug Resistance
29 Oct, 2017 | 01:39h | UTCHIV Drug Resistance: An Emerging Threat to Epidemic Control – New England Journal of Medicine (free)
Research: Pregnancy, thrombophilia, and the risk of a first venous thrombosis
29 Oct, 2017 | 01:36h | UTC“Women with antithrombin, protein C, or protein S deficiency or with homozygous factor V Leiden should be considered for antepartum or postpartum thrombosis prophylaxis, or both”.
Terbinafine is probably first choice oral drug for fungal toenail infection
29 Oct, 2017 | 01:31h | UTCTerbinafine is probably first choice oral drug for fungal toenail infection – NIHR Signal (free)
Original article: Oral antifungal medication for toenail onychomycosis – Cochrane Library (free)
Research: Payments by US pharmaceutical and medical device manufacturers to US medical journal editors
29 Oct, 2017 | 01:33h | UTC“Industry payments to journal editors are common and often large, particularly for certain subspecialties. Journals should consider the potential impact of such payments on public trust in published research”.
Guidelines on the management and treatment of portal hypertension
29 Oct, 2017 | 01:27h | UTC
Guidelines for the prevention and treatment of osteoporosis
29 Oct, 2017 | 01:29h | UTC
Research: Less dementia with oral anticoagulation in atrial fibrillation
29 Oct, 2017 | 01:25h | UTCLess dementia with oral anticoagulation in atrial fibrillation – European Heart Journal (free)
Commentaries: Blood-thinning drugs appear to protect against dementia in AF patients – OnMedica (free) AND Blood-thinning drugs ‘can reduce risk of dementia by up to 48%’ – The Guardian (free) AND Oral Anticoagulants Tied to Less Dementia in Patients with Atrial Fibrillation – Physician’s First Watch (free)
Research: Surgery for Drug-Resistant Epilepsy in Children
29 Oct, 2017 | 01:24h | UTCSurgery for Drug-Resistant Epilepsy in Children – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: First test of anti-epilepsy surgeries in children shows dramatic benefit – Reuters (free) AND Surgery Cuts Seizures in Drug-Resistant Epilepsy – MedPage Today (free registration required)
Eeffect of maternal multiple micronutrient supplementation on stillbirth, birth outcomes, and infant mortality
29 Oct, 2017 | 01:26h | UTCCommentaries: Antenatal multiple micronutrient supplementation: benefits beyond iron-folic acid alone – The Lancet Global Health (free) AND Multiple micronutrient supplements to mothers improve survival for newborn girls – Harvard School of Public health (free)
Related systematic review: Multiple-micronutrient supplementation for women during pregnancy – Cochrane Library (free summary)
Research: Depression and mortality in a longitudinal study
29 Oct, 2017 | 01:10h | UTCDepression and mortality in a longitudinal study: 1952–2011 – Canadian Medical Association Journal (free)
Commentaries: Depression strongly linked to higher long-term risk of early death for both women, men – ScienceDaily (free) AND Depression raises risk of early death – Medical News Today (free) AND Depression tied to shorter lifespan – Reuters (free)
Review: The Practice and Implications of Finding Fluid During Point-of-Care Ultrasonography
29 Oct, 2017 | 01:21h | UTCRelated JAMA Video: Finding Fluid With Point-of-Care Ultrasonography (free)
Guideline: Long-Acting Reversible Contraception
29 Oct, 2017 | 01:22h | UTCGuideline: Long-Acting Reversible Contraception: Implants and Intrauterine Devices – American College of Obstetricians and Gynecologists (free)
News release: LARC and Reproductive Choice (free)
Commentary: New Guidelines on LARC Released by ACOG – Medscape (free registration required)
Systematic review: Aerosol delivery during invasive mechanical ventilation
29 Oct, 2017 | 01:05h | UTCAerosol delivery during invasive mechanical ventilation: a systematic review – Critical Care (free)