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Research: Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine

20 Nov, 2017 | 14:18h | UTC

Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine – New England Journal of Medicine (free)

Commentaries: Neither Sodium Bicarbonate nor Oral Acetylcysteine Prevents Contrast-Induced Kidney Injury – Physician’s First Watch (free) AND PRESERVE: No Benefit from Sodium Bicarbonate, Acetylcysteine After Angiography – Medscape (free registration required)

 


Research: Effect of an Intervention to Promote Breastfeeding on Asthma, Lung Function, and Atopic Eczema at Age 16 Years

20 Nov, 2017 | 17:41h | UTC

Effect of an Intervention to Promote Breastfeeding on Asthma, Lung Function, and Atopic Eczema at Age 16 Years: Follow-up of the PROBIT Randomized Trial – JAMA Pediatrics (free)

Commentary: Prolonged breastfeeding linked to halving of later eczema risk – OnMedica (free)

 


Review: Eosinophilic esophagitis: update on management and controversies

20 Nov, 2017 | 14:15h | UTC

Eosinophilic esophagitis: update on management and controversies – The BMJ (free for 2 weeks)

 


Research: Sexual Activity as a Trigger for Sudden Cardiac Arrest

20 Nov, 2017 | 14:17h | UTC

Sexual Activity as a Trigger for Sudden Cardiac Arrest – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Sex poses little risk of triggering sudden cardiac arrest – Cedars-Sinai Heart Institute, via EurekAlert (free) AND Instances of cardiac arrest after sex are low, but so are the survival rates – Cardiovascular Business (free)

 


Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

20 Nov, 2017 | 14:17h | UTC

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery – New England Journal of Medicine (free)

Commentaries: TRICS III: Restrictive Red-Cell Transfusion Noninferior to Liberal Use in Cardiac Surgery – TCTMD (free) AHA: Restrictive Blood Transfusion OK for Select Patients – MedPage Today (free registration required)

Related article: Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA (free)

 


Research: Comparison of Hospital Resource Use and Outcomes Among Hospitalists, Primary Care Physicians, and Other Generalists

20 Nov, 2017 | 14:16h | UTC

Comparison of Hospital Resource Use and Outcomes Among Hospitalists, Primary Care Physicians, and Other Generalists – JAMA Internal Medicine (free)

Editorial: The Costs and Benefits of Hospital Care by Primary Physicians: Continuity Counts (free)

Audio interview: Hospital Resource Use and Outcomes Among Generalist Physicians (free)

Commentaries: Study: For Inpatients, Primary Care Docs Outperform Hospitalists – MedPage Today (free registration required) AND Mortality Lower When Inpatients See Their Own PCP in Hospital – Medscape (free registration required)

 


Research: Risks for blood clot in a vein may rise with increased TV viewing

20 Nov, 2017 | 14:14h | UTC

Risks for blood clot in a vein may rise with increased TV viewing – Presented at American Heart Association’s (AHA) Scientific Sessions 2017 (free)

Commentary: More TV viewing linked to higher risk of blood clots in veins – Medical News Today (free)

 


Research: Nut Consumption and Risk of Cardiovascular Disease

20 Nov, 2017 | 14:13h | UTC

Nut Consumption and Risk of Cardiovascular Disease – Journal of The American College of Cardiology (free)

Commentary: Eating Regular Variety of Nuts Associated With Lower Risk of Heart Disease – American College of Cardiology (free) AND Variety of nuts tied to lower risk of heart disease – Reuters (free)

 


Research: 20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

20 Nov, 2017 | 14:11h | UTC

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: ‘Unrelenting’: 20-Year Recurrence Risks in Breast Cancer – Medscape (free registration required) AND Breast cancer recurrence risk lingers years after treatment ends – MedicalXpress (free) AND Risk of breast cancer’s return continues long after treatment ends – Medical News Today (free)

 


Richard Lehman’s journal review, 13 November 2017

20 Nov, 2017 | 14:12h | UTC

Richard Lehman’s journal review, 13 November 2017 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


World Antibiotic Awareness Week, 13-19 November 2017

20 Nov, 2017 | 14:10h | UTC

World Antibiotic Awareness Week, 13-19 November 2017 – World Health Organization (free resources)

 


White Smoke From the Vatican? Not From Cigarettes

20 Nov, 2017 | 14:06h | UTC

White Smoke From the Vatican? Not From Cigarettes – The New York Times (10 articles per month are free)

Related: No more Holy Smokes – Vatican bans sale of cigarettes – Reuters (free) AND Holy smoke: Vatican bans duty-free cigarette sales – BBC (free)

“WHO welcomes the Vatican’s decision to ban the sale of cigarettes as of next year. Tobacco kills more than 7 million people every year” (RT @WHO see Tweet)

 


Research: Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement

20 Nov, 2017 | 14:08h | UTC

Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Mechanical heart valve often the safest choice – Stanford Medicine (free) AND Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement? – NEJM 360 Resident (free) AND Mechanical or Tissue Valve for AVR and MVR – American College of Cardiology, Latest in Cardiology (free) AND Mechanical Valves Show Mortality Benefit Over Biologic Valves – Medscape (free registration required) AND Heart valve replacement success may depend on age, valve type – Reuters (free)

 


Guideline: Bipolar disorder

20 Nov, 2017 | 14:08h | UTC

NICE Guideline: Bipolar disorder: assessment and management (free)

 


Research: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

20 Nov, 2017 | 14:10h | UTC

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct – New England Journal of Medicine (free)

Editorial: A New DAWN for Imaging-Based Selection in the Treatment of Acute Stroke (free)

Commentaries: Landmark study may impact standard stroke treatment guidelines – MedicalXpress (free) AND Thrombectomy Works While Infarct Core is Small – MedPage Today (free registration required)

“DAWN data: Consider a “tissue window” rather than a “time window”” (from MedPage Today)

 


Meta-Analysis: Choice of implant combinations in total hip replacement

20 Nov, 2017 | 14:07h | UTC

Choice of implant combinations in total hip replacement: systematic review and network meta-analysis – The BMJ (free)

Commentary: What is the most effective type of hip implant combination for patients undergoing a hip replacement? – University of Bristol (free)

“…there is no evidence that any of the newer hip implant combinations, such as ceramic or uncemented, are better than the widely used small head metal-on-plastic cemented hip combination, which has been commonly used since the 1960s”.

 


How to survive the medical misinformation mess

20 Nov, 2017 | 14:04h | UTC

How to survive the medical misinformation mess – European Journal of Clinical Investigation (free) (RT @RasoiniR see Tweet)

 


Meta-Analysis: Exercise for the Prevention of Low Back Pain

20 Nov, 2017 | 14:05h | UTC

Exercise for the Prevention of Low Back Pain: Systematic Review and Meta-Analysis of Controlled Trials – American Journal of Epidemiology (link to abstract – $ for full-text)

Commentary: Exercise may help prevent low back pain or make it less severe – Reuters (free)

Related meta-analysis: Prevention of Low Back Pain: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free)

 


Fri, November 17 – 10 Stories of The Day!

17 Nov, 2017 | 01:21h | UTC

 

1 – Exploring Attributes of High-Value Primary Care – Annals of Family Medicine (free)

Commentaries: Lower cost, higher quality primary care practices are distinguished by six attributes – American Academy of Family Physicians, via ScienceDaily (free) AND Identifying ‘high-value’ practices in primary care; a Stanford study pinpoints key attributes – Stanford Medicine (free)

 

2 – Critical Lessons From High-Value Oncology Practices – JAMA Oncology (free)

Editorial: Strategies to Achieve High-Value Oncology Care: A Beginning (free)

Audio interview: Critical Lessons From High-Value Oncology Practices (free)

Commentary: High-Value Cancer Care Keeps Costs Down? Yes, It’s Possible! – Medscape (free registration required) AND High-value oncology practices include “support for the patient journey” – Stanford Medicine (free)

 

3 – Changing Health Care Compensation by Rewarding Value-Based Outcomes – NEJM Catalyst (free)

 

4 – Speed of processing training results in lower risk of dementia – Alzheimer’s & Dementia: Translational Research & Clinical Interventions (free)

Commentaries: Can brain training reduce dementia risk? Despite new research, the jury is still out – The Guardian (free) AND Nonpharma Intervention Cuts Dementia Risk by a Third – Medscape (free registration required) AND Dementia breakthrough? Brain-training game ‘significantly reduces risk’ – Medical News Today (free)

“There are good reasons to be cautious about a new study claiming computer-based training can reduce the risk of dementia. But what does work?” (from The Guardian).

 

5 – Timing of Angiography and Outcomes in High-Risk Patients With Non–ST-Segment–Elevation Myocardial Infarction Managed Invasively – Circulation (free)

“High risk NSTEMI undergoing cath within 12 hours had lower risk of death and MI at 180 days” (RT @CircAHA see Tweet)

 

6 – Why we should care that many editors of top medical journals get healthcare industry payments – Health News Reviews (free)

Original article: Payments by US pharmaceutical and medical device manufacturers to US medical journal editors: retrospective observational study – The BMJ (free)

 

7 – Review: Undernutrition and severe acute malnutrition in children – The BMJ (free)

Infographic: Screening and referring children under 5 years old with acute undernutrition (free PDF)

 

8 – Review: Diabetic foot – The BMJ (free)

Infographic: A visual overview of the primary care assessment and monitoring of a diabetic foot (free PDF)

 

9 – Review of Strategies to Reduce Central Line-Associated Bloodstream Infection (CLABSI) and Catheter-Associated Urinary Tract Infection (CAUTI) in Adult ICUs – Journal of Hospital Medicine (free) (via @brhospitalist)

 

10 – Simple steps help prevent ICU delirium – ACP Hospitalist (free)

 


Research: Circulating vitamin D concentration and risk of seven cancers

20 Nov, 2017 | 14:04h | UTC

Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study – The BMJ (free)

Commentary: Vitamin D level not associated with cancer risk – Clinical Adviser (free)

“These results, in combination with previous literature, provide evidence that population-wide screening for vitamin D deficiency and subsequent widespread vitamin D supplementation should not currently be recommended as a strategy for primary cancer prevention”.

 


Thu, November 16 – 10 Stories of The Day!

16 Nov, 2017 | 03:11h | UTC

 

1 – Periodic preventive health visits: a more appropriate approach to delivering preventive services – Canadian Task Force on Preventive Health Care (free)

Summary: Periodic preventive health visits: A more appropriate approach to delivering preventive services (free)

News release: Annual checkups do not result in better health outcomes, national task force reaffirms (free)

 

2 – Sudden Cardiac Arrest during Participation in Competitive Sports – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Sudden Cardiac Arrest Rare During Competitive Sports – Physician’s First Watch (free) AND Cardiac arrest study in young athletes raises heart screening questions – Reuters (free) AND Cardiac Arrest Rare in Young Athletes But Tough to Predict – Health (free) AND Screening programs unlikely to prevent sudden cardiac arrest in competitive athletes – St. Michael’s Hospital, via EurekAlert (free)

 

3 – Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosain health care facilities – World Health Organization (free)

Commentary: WHO offers guidance on carbapenem-resistant bacteria – CIDRAP (free)

 

4 – CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning – Stanford ML Group (free)

“We develop an algorithm that can detect pneumonia from chest X-rays at a level exceeding practicing radiologists”

 

5 – The Patients vs. Paperwork Problem for Doctors – The New York Times (10 articles per month are free)

Related guideline: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free)

 

6 – World Chronic Obstructive Pulmonary Disease Day, 15 November 2017: A round up of Cochrane evidence – Evidently Cochrane (free)

 

7 – Comparative clinical effectiveness and cost effectiveness of endovascular strategy vopen repair for ruptured abdominal aortic aneurysm: three year results of the IMPROVE randomised trial – The BMJ (free)

Editorial: Endovascular or open repair for ruptured abdominal aortic aneurysm? (free)

Commentary: Keyhole surgery more effective than open surgery for ruptured aneurysm – MedicalXpress (free)

 

8 – Health Effects and Public Health Concerns of Energy Drink Consumption in the United States: A Mini-Review – Frontiers in Public Health (free)

Commentaries: Serious health risks associated with energy drinks – ScienceDaily (free)

“To curb this growing public health issue, policy makers should regulate sales and marketing towards children and adolescents and set upper limits on caffeine” (from ScienceDaily)

 

9 – Effects of Bariatric Surgery in Obese Patients With Hypertension: The GATEWAY Randomized Trial (Gastric Bypass to Treat Obese Patients With Steady Hypertension) – Circulation (free)

Commentary: Bariatric Surgery Can Lead to HTN ‘Remission’ in Obese: GATEWAY – Medscape (free registration required) AND Gastric Bypass to Treat Obese Patients With Steady Hypertension – GATEWAY – American College of Cardiology, Latest in Cardiology (free)

 

10 – Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease, and cancer: systematic review and meta-analysis – The BMJ (free)

 


Mon, November 20 – 10 Stories of The Day!

20 Nov, 2017 | 03:31h | UTC

 

1 – News release: New global commitment to end tuberculosis – World Health Organization (free)

Commentary: Global health ministers commit to end TB – CIDRAP (free)

Related report: Global tuberculosis report 2017 – World Health Organization (free) AND News Release: WHO report signals urgent need for greater political commitment to end tuberculosis (free)

 

2 – Infection prevention and control measures and tools for the prevention of entry of carbapenem-resistant Enterobacteriaceae into healthcare settings: guidance from the European Centre for Disease Prevention and Control – Antimicrobial Resistance & Infection Control (free)

Related document: Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosain health care facilities – World Health Organization (free)

 

3 – The association between paternal and adolescent depressive symptoms: evidence from two population-based cohorts – The Lancet (free)

Editorial: The effect of paternal depression on depressive symptoms in adolescent offspring (free)

Commentaries: Dads’ Depression Tied to Increased Depression Risk in Teenage Children – Physician’s First Watch (free) AND Teenage depression linked to father’s depression – University College London, via ScienceDaily (free)

 

4 – The High Costs of Unnecessary Care – JAMA (free)

 

5 – “Maybe I Will Just Send a Quick Text…” – An Examination of Drivers’ Distractions, Causes, and Potential Interventions – Frontiers in Psycology (free)

Commentaries: Young Men, Frequent Drivers Most Likely To Get Distracted While Driving – NPR (free) AND Risk of distracted driving predicted by age, gender, personality and driving frequency – MedicalXpress (free)

 

6 – Dog ownership and the risk of cardiovascular disease and death – a nationwide cohort study – Scientific Reports (free)

Commentaries: Dog ownership linked to lower mortality – Uppsala University, via ScienceDaily (free) AND Owning A Dog May Help Your Heart, Study Shows – Forbes (free)

 

7 – Bird Flu Is Spreading in Asia, Experts (Quietly) Warn – The New York Times (10 articles per month are free)

 

8 – Taking Care of the Physician – The New York Times (10 articles per month are free)

 

9 – Pearls and pitfalls in comprehensive critical care echocardiography – Critical Care (free)

 

10 – Validation of the Ottawa Subarachnoid Hemorrhage Rule in patients with acute headache – Canadian Medical Association Journal (free)

Commentaries: Thunderclap Headache: Ottawa Rule To Exclude Subarachnoid Bleeding – Medical Research (free) AND New tool identifies headache patients at risk of aneurysms in emergency department – CMAJ, via EurekAlert (free)

 


Meta-Analysis: Long-term Sustainability of Diabetes Prevention Approaches

20 Nov, 2017 | 14:03h | UTC

Long-term Sustainability of Diabetes Prevention Approaches: A Systematic Review and Meta-analysis of Randomized Clinical Trials – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Lifestyle Modifications Slow Progression To Diabetes As Effectively As Medications – Medical Research (free) AND Lifestyle changes successfully reduce incidence of diabetes – MedicalXpress (free) AND Lifestyle changes—not medications—linked to sustained risk reduction for diabetes – Cardiovascular Business (free)

 


Wed, November 15 – 10 Stories of The Day!

15 Nov, 2017 | 00:52h | UTC

 

1 – Association of Blood Pressure Lowering With Mortality and Cardiovascular Disease Across Blood Pressure Levels: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Treating modestly high blood pressure may not boost survival odds – Reuters (free) AND No cardiovascular disease reduction with intensive blood pressure lowering treatment – Umea University, via EurekAlert (free)

See also new AHA/ACC Hypertension Guidelines and related resources in our November 13th issue (see #1)

“”Primary preventive BP lowering is associated with reduced risk for death and CVD if baseline SBP is 140 mm Hg or higher.” published same day as @ACCinTouch guideline w/SBP goals <130 mm Hg. Cognitive dissonance?” (RT @kennylinafp see Tweet)

 

2 – Noninvasive Cardiac Testing vs Clinical Evaluation Alone in Acute Chest Pain: A Secondary Analysis of the ROMICAT-II Randomized Clinical Trial – JAMA Internal Medicine (free)

Editorial: Acute Chest Pain in the Emergency Department (free)

Commentaries: Does Clinical Evaluation Plus Noninvasive Cardiac Testing Improve Outcomes in Emergency Department Patients with Chest Pain? – The JAMA Network (free) AND Noninvasive Cardiac Testing No Better Than Clinical Eval for Low-Risk Acute Chest Pain – Physician’s First Watch (free)

“Non-invasive testing of chest pain patients in the ED – longer stay; more testing, radiation and cost; no benefit”. (RT @JAMA_current see Tweet)

 

3 – World Antibiotic Awareness Week, 13-19 November 2017: A round up of Cochrane evidence – Evidently Cochrane (free)

 

4 – Guidelines on the management of abnormal liver blood tests – Gut (free)

 

5 – Increases in Depressive Symptoms, Suicide-Related Outcomes, and Suicide Rates Among U.S. Adolescents After 2010 and Links to Increased New Media Screen Time – Clinical Psychological Science (free)

Commentaries: Increased Hours Online Correlate With An Uptick In Teen Depression, Suicidal Thoughts – NPR (free) AND Smartphones a likely culprit in the recent decline in teen mental health – STAT (free)

 

6 – Tinder and Grindr don’t want to talk about their role in rising STDs – VOX (free)

 

7 – Review: The Diagnosis of Chronic Coronary Heart Disease – Deutsches Ärzteblatt international (free)

 

8 – Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery – Annals of Internal Medicine (free)

Commentaries: Perioperative aspirin may improve short-term outcomes after noncardiac surgery in patients with prior PCI – ACP Internist (free) AND Aspirin can prevent heart attacks after noncardiac surgery in patients with prior PCI – University of Alberta Faculty of Medicine & Dentistry, via ScienceDaily (free) AND Aspirin Protective Against Early Death/MI in Prior PCI Patients Undergoing Noncardiac Surgery – TCTMD (free)

 

9 – Perinatal mortality associated with induction of labour versus expectant management in nulliparous women aged 35 years or over: An English national cohort study – PLOS Medicine (free)

Commentaries: Labor induction at 40 weeks associated with lower risk of perinatal mortality – PLOS, via ScienceDaily (free) AND Induction at Term Cuts Rates of Infant Death in Older First-Time Moms – MedPage Today (free registration required) Inducing Older Moms at 40 Weeks May Lower Stillbirth Risk – Medscape (free registration required)

 

10 – Effect of an Intervention to Promote Breastfeeding on Asthma, Lung Function, and Atopic Eczema at Age 16 Years: Follow-up of the PROBIT Randomized Trial – JAMA Pediatrics (free)

Commentary: Prolonged breastfeeding linked to halving of later eczema risk – OnMedica (free)

 


Exercise guidelines for adults with spinal cord injury

14 Nov, 2017 | 20:37h | UTC

Evidence-based scientific exercise guidelines for adults with spinal cord injury: an update and a new guideline – Spinal Cord (free)

 


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