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Practice Guideline: Mild Cognitive Impairment

4 Jan, 2018 | 17:28h | UTC

Practice guideline update summary: Mild cognitive impairment – American Academy of Neurology (free PDF)

Commentary: Mild cognitive impairment: a practice guideline update – Clinical Advisor (free)

“For patients diagnosed with MCI, clinicians may choose NOT to offer cholinesterase inhibitors”.

“If clinicians choose to offer cholinesterase inhibitors, they must first discuss with patients the fact that this is an off-label prescription not currently backed by empirical evidence”.

 


Research: Association of an Enhanced Recovery Program With Colectomy Outcomes

4 Jan, 2018 | 18:58h | UTC

Association of an Enhanced Recovery Pilot With Length of Stay in the National Surgical Quality Improvement Program – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Enhanced-recovery Protocol Linked to Better Colectomy Outcomes – Reuters, via Medscape (free registration required)

Related guideline: Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons (free)

See other Enhanced Recovery After Surgery (ERAS) Guidelines and Reviews in our collection and in the ERAS Society Website.

 


Delayed Antibiotic Prescribing’ for Respiratory Infections may Reduce Antibiotic Use

4 Jan, 2018 | 17:25h | UTC

A strategy of ‘delayed antibiotic prescribing’ for respiratory infections may reduce antibiotic use – NIHR Signal (free)

Original article: Delayed antibiotic prescriptions for respiratory infections – Cochrane Library (free) AND Summary: Delayed antibiotic prescriptions for respiratory tract infections – Cochrane Library (free)

 


Research: Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma

4 Jan, 2018 | 17:13h | UTC

Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma – The New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Stem Cell Transplant for Severe Scleroderma Improves Survival, Quality of Life – NIH (free) AND Stem Cell Transplantation Offers Hope For Severe Scleroderma – MedicalResearch (free)

 


Research: Increased Cardiovascular Risk After Initiation of Inhaled Long-Acting Bronchodilators in Patients With COPD

4 Jan, 2018 | 17:16h | UTC

Association of Cardiovascular Risk With Inhaled Long-Acting Bronchodilators in Patients With Chronic Obstructive Pulmonary Disease: A Nested Case-Control Study – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Starting new COPD inhaler tied to heart attack risk – Reuters (free) AND New Use of Long-Acting Bronchodilators in COPD Tied to Increased Cardiovascular Risk – Physician’s First Watch (free) AND COPD patients beginning inhaler therapy at greater short-term risk for CVD – Cardiovascular Business (free)

 


Guidelines for the Management of Acne

4 Jan, 2018 | 17:12h | UTC

Guidelines for the Management of Acne: Recommendations From a French Multidisciplinary Group – British Journal of Dermatology, via Medscape (free registration required)

 


Systematic Review: Sugar-Sweetened Beverages and Weight Gain in Children and Adults

4 Jan, 2018 | 17:11h | UTC

Sugar-Sweetened Beverages and Weight Gain in Children and Adults: A Systematic Review from 2013 to 2015 and a Comparison with Previous Studies – Obesity Facts (free)

Commentary: New review confirms link between consumption of sugar-sweetened beverages and overweight, obesity – The Medical News (free) AND Review confirms link between sugary drinks and obesity – Medical News Today (free)

 


Meta-Analysis: Prevalence of COPD in the Global Population with HIV

4 Jan, 2018 | 17:10h | UTC

Prevalence of chronic obstructive pulmonary disease in the global population with HIV: a systematic review and meta-analysis – The Lancet Global Health (free)

Invited commentary: Collision of communicable and non-communicable disease epidemics—the case of HIV and COPD (free)

 


Video: Do Less, Not More—Reducing Waste in Health Care

4 Jan, 2018 | 17:09h | UTC

Video: Do Less, Not More—Reducing Waste in Health Care – NEJM Catalyst (free)

 


Research: Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression

4 Jan, 2018 | 17:07h | UTC

Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial – The American Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Adjunctive Ketamine Appears to Reduce Suicidal Thoughts in Depressed Patients for Up to Six Weeks – Psychiatric News Alert (free) AND Ketamine Rapidly Reduces Suicidal Ideation – Medscape (free registration required)

 


Infographic vs Text: Evidence Throwdown!

4 Jan, 2018 | 17:09h | UTC

Infographic vs Text: Evidence Throwdown! – Absolutely Maybe, in PLOS Blogs (free) (via @hildabast see Tweet)

Related: No difference in knowledge obtained from infographic or plain language summary of a Cochrane systematic review: three randomized controlled trials – Journal of Clinical Epidemiology (free PDF)

 


Thyroid Storm: A Japanese Perspective

4 Jan, 2018 | 17:08h | UTC

Thyroid Storm: A Japanese Perspective – Thyroid (free)

Commentary: New diagnostic criteria and treatment guidelines proposed for thyroid storm – EurekAlert (free)

 


Sham Surgeries: A Tale of Medical Reversals & the Role of the Media

4 Jan, 2018 | 17:03h | UTC

Sham surgeries: A tale of medical reversals & the role of the media – HealthNewsReview (free)

Related commentaries: Sham Controls in Device Trials Gain Favor After ORBITA – MedPage Today (free registration required) AND ORBITA: Another clinical trial demonstrating the need for sham controls in surgical trials – Science-Based Medicine (free)

 


Meta-Analysis: Neoadjuvant vs Adjuvant Chemotherapy in Early Breast Cancer

4 Jan, 2018 | 17:05h | UTC

Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials – The Lancet Oncology (free)

Commentaries: Neoadjuvant chemotherapy in breast cancer: more than just downsizing – The Lancet Oncology (free) AND Long-Term Outcomes for Neoadjuvant vs Adjuvant Chemotherapy in Early Breast Cancer – PracticeUpdate (free registration required)

 


Meta-Analysis: Carfilzomib-Associated Cardiovascular Adverse Events

4 Jan, 2018 | 17:01h | UTC

Carfilzomib-Associated Cardiovascular Adverse Events: A Systematic Review and Meta-analysis – JAMA Oncology (link to abstract – $ for full-text)

Commentaries: Carfilzomib can lead to cardiovascular toxicity in multiple myeloma patients – eCancer News (free) AND Higher Rates of Cardiovascular Adverse Events in Patients with MM Treated With Carfilzomib – AJMC (free) AND Important CV Risk Seen With Carfilzomib in Multiple Myeloma – Medscape (free registration required)

 


Meta-Analysis: Clinical and Economic Impact of Antibiotic Resistance in Developing Countries

4 Jan, 2018 | 17:02h | UTC

Clinical and economic impact of antibiotic resistance in developing countries: A systematic review and meta-analysis – PLOS One (free) (via @CIDRAP_ASP)

 


Research: Retroperitoneal Lymphadenectomy for High Risk, Nonmetastatic Renal Cell Carcinoma

4 Jan, 2018 | 16:59h | UTC

Retroperitoneal Lymphadenectomy for High Risk, Nonmetastatic Renal Cell Carcinoma: An Analysis of the ASSURE (ECOG-ACRIN 2805) Adjuvant Trial – Journal of Urology (free for a period)

Commentary: Lymphadenectomy in Renal Cell Carcinoma: No Benefit? – Medscape (free registration required)

 


Research: Diagnostic Accuracy of MRI to Identify Clear Cell Renal Cell Carcinoma in Renal Masses

4 Jan, 2018 | 17:00h | UTC

Diagnostic Accuracy of Multiparametric Magnetic Resonance Imaging to Identify Clear Cell Renal Cell Carcinoma in cT1a Renal Masses – Journal of Urology (free for a period)

Commentary: State-of-the-art MRI technology bypasses need for biopsy – UT Southwestern Medical Center, via ScienceDaily (free)

 


Research: Socioeconomic Position, Alcohol Drinking Patterns, and Cardiovascular Mortality

4 Jan, 2018 | 16:56h | UTC

Life course socioeconomic position, alcohol drinking patterns in midlife, and cardiovascular mortality: Analysis of Norwegian population-based health surveys – PLOS Medicine (free) (via @EricTopol see Tweet)

Commentary: Heart benefit of moderate drinking greater in wealthy people – Reuters (free)

 


Research: Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes

4 Jan, 2018 | 16:57h | UTC

Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Weaning To Hydrolyzed Infant Formula Did Not Reduce Risk of Type 1 Diabetes – MedicalResearch (free) AND Study Finds No Link Between Baby Formula Made From Cow’s Milk And Diabetes Risk – NPR (free) AND Avoiding Cow’s Milk Doesn’t Cut Type 1 Diabetes Risk – Medscape (free registration required) AND Modifying Baby Formula Doesn’t Prevent Type 1 Diabetes in Children – University of Pittsburg (free)

 


$850,000 per Patient for Blindness Gene Therapy

4 Jan, 2018 | 16:53h | UTC

Spark to charge $850,000 per patient for blindness gene therapy – Reuters (free) AND US drug firm offers cure for blindness – at $425,000 an eye – The Guardian (free) AND Spark prices its gene therapy as most expensive U.S. medicine — but with plans to ease cost concerns – STAT (free)

 


Research: Co-administration of Vancomycin and Piperacillin-Tazobactam and Renal Dysfunction

4 Jan, 2018 | 16:55h | UTC

Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients – Critical Care (free)

See also related meta-analysis: Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults

 


Guidelines on the Treatment of Adults With Vestibular Schwannomas

4 Jan, 2018 | 16:58h | UTC

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Treatment of Adults With Vestibular Schwannomas: Executive Summary – Neurosurgery (free)

 


Research: Screening in the Community to Reduce Fractures in Older Women

4 Jan, 2018 | 16:54h | UTC

Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Screening could catch a quarter of hip fractures before they happen – University of Manchester (free) AND FRAX Screening Reduces Hip Fractures in Healthy Older Women – Medscape (free registration required)

 


Transfusing blood Close to its use-by date does not increase deaths in critically ill adults

3 Jan, 2018 | 14:23h | UTC

Transfusing blood close to its use-by date does not increase deaths in critically ill adults – NIHR Signal (free)

Original article: Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults – New England Journal of Medicine (link to abstract – $ for full-text)

 


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