Archives
Systematic Review: Marijuana Use and Cardiovascular Risk Factors and Outcomes
25 Jan, 2018 | 23:47h | UTCAssociations Between Marijuana Use and Cardiovascular Risk Factors and Outcomes: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Insufficient evidence to determine if marijuana use can affect cardiovascular risk – 2 Minute Medicine (free) AND Scant Evidence for Heart Benefits, Risks with Cannabis – MedPage Today (free registration required)
Systematic Review: Interventions to Reduce Adverse Gastrointestinal Effects of Pelvic Radiotherapy for Primary Pelvic Cancers
25 Jan, 2018 | 23:50h | UTCInterventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers – Cochrane Library (free)
Summary: Interventions to reduce digestive side effects of pelvic x-ray treatment – Cochrane Library (free)
Concerns About Composite Reference Standards in Diagnostic Research
25 Jan, 2018 | 23:43h | UTCResearch Methods & Reporting: Concerns about composite reference standards in diagnostic research – The BMJ (free)
Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors
25 Jan, 2018 | 23:44h | UTCCommentary: Leading medical organizations update lung cancer guideline – International Association for the Study of Lung Cancer, via EurekAlert (free)
Busting 10 Common Myths about the “Greatest Pandemic in History”
25 Jan, 2018 | 21:03h | UTCBusting 10 Common Myths about the “Greatest Pandemic in History” – Scientific American (free)
Guideline: Laboratory Tests to Monitor Drug Therapy in Pain Management Patients
25 Jan, 2018 | 21:04h | UTCCommentary: AACC Releases Practice Guidelines for Using Laboratory Drug Tests to Combat Opioid Addiction, Overdoses – American Association for Clinical Chemistry (AACC) (free)
Guideline: Nutrition in Critically Ill Patients
25 Jan, 2018 | 21:02h | UTCSource: Critical Care Reviews Newsletter
Review: Cardiorenal Syndrome in Sepsis
25 Jan, 2018 | 21:00h | UTCCardiorenal syndrome in sepsis: A narrative review – Journal of Critical Care (free)
Source: Critical Care Reviews Newsletter
Do You Work More Than 39 Hours a Week? Your Job Could be Killing You
25 Jan, 2018 | 21:01h | UTCDo you work more than 39 hours a week? Your job could be killing you – The Guardian (free)
Guideline: Neuroendovascular Management of Emergent Large Vessel Occlusion
25 Jan, 2018 | 20:58h | UTC
Position Statement: Cross-infection Risk in Patients with Bronchiectasis
25 Jan, 2018 | 20:57h | UTC
Systematic Review: Routine Antibiotic Prophylaxis After Normal Vaginal Birth
25 Jan, 2018 | 20:56h | UTCRoutine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity – Cochrane Library (link to abstract – $ for full-text)
Related Guideline: Antibiotic Prophylaxis in Obstetric Procedures – Society of Obstetricians and Gynaecologists of Canada (free)
Guideline: Leptospirosis
25 Jan, 2018 | 20:59h | UTCSource: Critical Care Reviews Newsletter
Research: Incidence of STI Before and After Pre-Exposure Prophylaxis for HIV
25 Jan, 2018 | 20:51h | UTCIncidence of sexually transmitted infections before and after Pre-Exposure Prophylaxis for HIV: a cohort study – AIDS (link to abstract – $ for full-text)
Commentary: Preexposure Prophylaxis for HIV Tied to Increased STI Rates – Medscape (free registration required)
Gene Editing – And What it Really Means to Rewrite the Code of Life
25 Jan, 2018 | 20:53h | UTCGene editing – and what it really means to rewrite the code of life – The Guardian (free)
Related: Correction of a pathogenic gene mutation in human embryos (free articles and commentaries) AND Simple guide to CRISPR, one of the biggest science stories of the decade – VOX (free)
Research: Socioeconomic Outcomes of Women Who Receive and Women Who Are Denied Wanted Abortions
25 Jan, 2018 | 20:52h | UTCCommentary: Opinion: Restricting access to abortion makes poor women poorer – LA Times (free)
Review: Biology and Therapy of Medullary Thyroid Carcinoma
25 Jan, 2018 | 20:46h | UTCRecent advances in the biology and therapy of medullary thyroid carcinoma – F1000 Research (free)
Research: Association of Depression With Mortality in Older Adults Undergoing TAVR and SAVR
25 Jan, 2018 | 20:50h | UTCAssociation of Depression With Mortality in Older Adults Undergoing Transcatheter or Surgical Aortic Valve Replacement – JAMA Cardiology (link to abstract – $ for full-text)
Commentaries: Depression May Increase Risk of Death Following Heart Procedure, Study Suggests – Psychiatric News Alert (free) AND One-Third of TAVR and SAVR Patients Are Depressed, Upping Mortality Risk – TCTMD (free) AND Association of Depression With Mortality After SAVR and TAVR – American College of Cardiology, Latest in Cardiology (free)
Review: Sleep Apnea and its Role in Transportation Safety
25 Jan, 2018 | 20:45h | UTCSleep apnea and its role in transportation safety – F1000 Research (free)
Review: Vancomycin-resistant Enterococcus Infection in the Hematopoietic Stem Cell Transplant Recipient
25 Jan, 2018 | 20:48h | UTC
Wed, January 24 – 10 Stories of The Day!
24 Jan, 2018 | 01:18h | UTC
1 – Report: Public Health Consequences of E-Cigarettes – National Academies of Sciences, Engineering, and Medicine (free PDF)
Press release: New Report One of the Most Comprehensive Studies on Health Effects of E-Cigarettes; Finds That Using E-Cigarettes May Lead Youth to Start Smoking, Adults to Stop Smoking (free)
Commentaries: E-Cigarettes Likely Encourage Kids To Try Tobacco But May Help Adults Quit – NPR (free) AND 4 big takeaways from the most comprehensive report on e-cigarettes yet – VOX (free) AND Vaping Can Be Addictive and May Lure Teenagers to Smoking, Science Panel Concludes – The New York Times (10 articles per month are free)
See prognostic calculator: Prediction models for 3 month outcome after aSAH
3 – Antithyroid Drugs and Congenital Malformations: A Nationwide Korean Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: First trimester exposure to antithyroid drugs associated with increased risk of birth defects – 2 Minute Medicine (free) AND Use of Antithyroid Drugs Early in Pregnancy Tied to Birth Defect Risk – Physician’s First Watch (free) AND First trimester exposure to antithyroid drugs linked with birth defects – OnMedica (free)
Commentary: AAP Issues Recommendations for Improving Early-Childhood Nutrition – Physician’s First Watch (free) AND These Are the Best Foods for a Baby’s Brain – TIME (free)
5 – Robust research needs many lines of evidence – Nature (free)
Source: Critical Care Reviews Newsletter
8 – Choosing Wisely Campaign: American Society of Breast Surgeons – Benign Breast Disease: Five Things Physicians and Patients Should Question (free)
Commentary: Choosing Wisely: 5 Procedures to Avoid in Benign Breast Disease – Physician’s First Watch (free)
See more on the Choosing Wisely initiative in our April 5 issue (see #6)
9 – Reduction of PTSD Symptoms With Pre-Reactivation Propranolol Therapy: A Randomized Controlled Trial – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Propranolol May Help Patients With PTSD – Psychiatric News Alert (free) AND Propranolol May Fill ‘Dire’ Treatment Need for PTSD – Medscape (free registration required)
10 – Starting antiretroviral therapy immediately after HIV diagnosis reduces transmission of the virus – NIHR Signal (free)
Original article: Implications for a policy of initiating antiretroviral therapy in people diagnosed with human immunodeficiency virus: the CAPRA research programme – Programme Grants for Applied Research (free)
Review: Predictors of Outcome in Phaeochromocytomas and Paragangliomas
25 Jan, 2018 | 20:42h | UTCPredictors of outcome in phaeochromocytomas and paragangliomas – F1000 Research (free)
Thu, January 25 – 10 Stories of The Day!
25 Jan, 2018 | 00:56h | UTC
Commentaries: More stroke patients eligible for crucial treatments under new guidelines – American Heart Association News (free) AND More stroke patients may receive crucial treatments under new guideline – AHA/ASA Newsroom (free)
“A new guideline for treating acute ischemic stroke recommends an increased treatment window for mechanical clot removal from six hours to up to 24 hours in certain patients with clots in large vessels”. (from AHA/ASA Newsroom)
Commentaries: Brain-scan guided emergency stroke treatment can save more lives – NIH News Releases (free) AND Study confirms late clot extraction can save brain cells of stroke victims – Reuters (free) AND New Findings Could Save Lives of More Stroke Patients – The New York Times (10 articles per month are free)
Related article: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct – New England Journal of Medicine (link to abstract – $ for full-text)
3 – Perspectives: To Care Is Human — Collectively Confronting the Clinician-Burnout Crisis – New England Journal of Medicine (free) AND Beyond Burnout — Redesigning Care to Restore Meaning and Sanity for Physicians (free)
Related: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free)
4 – Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus – JAMA Neurology (free for a period)
Editorial: Time May Be of the Essence in the Treatment of Pediatric Patients With Refractory Convulsive Status Epilepticus (free)
Commentary: Delays Raise Death Risk in Kids with Status Epilepticus – MedPage Today (free registration required)
“These findings may change the perception of acute seizure and status epilepticus treatment, tentatively converting it into an extremely time-sensitive emergency that is similar to stroke or other cardiovascular events”.
Related: Canadian Deprescribing Network (CaDeN) (free) AND CaDeN Deprescribing Guidelines and Algorithms (free) AND Deprescribing guidelines for the elderly – Ontario Pharmacy Evidence Network (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND 11 Drugs You Should Seriously Consider Deprescribing – Medscape Slideshow (free registration required) AND Current and future perspectives on the management of polypharmacy – BMC Family Practice (free)
7 – Guideline: Oesophago-gastric cancer: assessment and management in adults – National Institute for Health and Care Excellence (NICE) (free)
8 – Guideline: Age-related macular degeneration – National Institute for Health and Care Excellence (NICE) (free)
Commentaries: Largest Study to Date Supports Surgical LAA Closure in A-fib Patients – TCTMD (free) AND Thromboembolism Less Likely With LAA Closure Added to Cardiac Surgery – MedPage Today (free registration required)
Randomized trials are needed to confirm these interesting findings.
10 – Trends in Survival After In-Hospital Cardiac Arrest During Nights and Weekends – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Survival From In-Hospital Cardiac Arrest Improves But Still Worse on Nights and Weekends – MedicalResearch.com (free)
AND Hospital patients less likely to survive ‘off-hours’ cardiac arrest – Reuters (free) AND You are still more likely to die in a hospital on the weekend – CNN (free)
See also a recent meta-analysis showing the “weekend effect” in surgical patients
Review: Electroanalgesia and Laser Therapies for Pain Management
25 Jan, 2018 | 20:44h | UTC
Guideline Synopsis: Management of High Blood Pressure in Adults
23 Jan, 2018 | 16:57h | UTCRelated: Redefining Hypertension: Assessing the New Blood-Pressure Guidelines – New England Journal of Medicine (free) AND AAFP Decides to Not Endorse AHA/ACC Hypertension Guideline – American Academy of Family Physicians (free)


