Archives
Guideline: Diagnosis and Management of Pediatric Autoimmune Liver Disease
9 Feb, 2018 | 11:36h | UTC
Research: Cardiomyopathy Registry of the EURObservational Research Programme of the European Society of Cardiology
9 Feb, 2018 | 11:37h | UTCCommentary: Four in 10 cardiomyopathies — a major cause of sudden death in young people — are genetic – European Society of Cardiology, via ScienceDaily (free)
Review: Nonsuicidal Self-Injury in Adolescents
9 Feb, 2018 | 11:34h | UTCNonsuicidal Self-Injury in Adolescents – Deutsches Ärzteblatt international (free)
Meta-Analysis: Beta-Blockers for Heart Failure with Reduced, Mid-Range, and Preserved Ejection Fraction
9 Feb, 2018 | 11:34h | UTC
Systematic Review: Interventions Delivered by Mobile Phones for the Prevention of Non-Communicable Diseases
9 Feb, 2018 | 11:31h | UTC
Research: Lactation Duration and Progression to Diabetes in Women
9 Feb, 2018 | 11:29h | UTCCommentary: Breastfeeding May Halve Diabetes Risk in Women – Medscape (free registration required)
Research: Handover of Anesthesia Care and Adverse Postoperative Outcomes
9 Feb, 2018 | 11:27h | UTCAssociation Between Handover of Anesthesia Care and Adverse Postoperative Outcomes Among Patients Undergoing Major Surgery – JAMA (link to abstract – $ for full-text)
Commentary: Anesthesia Care Hand Off Mid-Surgery Associated With Substantial Risk – MedPage Today (free registration required) AND Complete Handoffs by Anesthesiologists Tied to Poor Outcomes – Medscape (free registration required)
Fri, February 9 – 10 Stories of The Day!
9 Feb, 2018 | 00:26h | UTC
1 – 2018 annual review of the Blueprint list of priority diseases – World Health Organization (free) (via @equitylist)
Key actions: Diseases for which R&D preparedness activities are already in development – World Health Organization (free)
2 – Free online course. Starts 12 February 2018. The Lancet Maternal Health Series: Global Research and Evidence – London School of Hygiene & Tropical Medicine, via Future Learn
“Hear the latest expert evidence from The Lancet Maternal Health Series and learn what you can do to improve maternal healthcare”.
Editorial: The failure of anti-obesity programmes in schools (free)
Commentary: Obesity crisis can’t be solved by schools – major new study – The Conversation (free) AND Schools are not the answer to childhood obesity epidemic, study shows – The Guardian (free)
“In the words of Winston Churchill, “However beautiful the strategy, you should occasionally look at the results.”” (from editorial)
4 – Review: The Management of Multi-vessel disease (MVD) in STEMI: The Science and Art of Decision-Making in STEMI – American College of Cardiology, Latest in Cardiology (free)
5 – Update: Stroke in Women: Recognizing Opportunities for Prevention and Treatment – Stroke (free PDF for a limited period)
6 – Update: Impact of Conventional Stroke Risk Factors on Stroke in Women – Stroke (free PDF for a limited period)
7 – Update: Stroke Risk Factors Unique to Women – Stroke (free PDF for a limited period)
Infographic: The vital first 10 minutes (free PDF)
Even slight changes within the normal Apgar score range (7-10) from five to 10 minutes have a major influence in the risks of cerebral palsy and epilepsy.
10 – Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial – The Lancet child & Adolescent Health (link to abstract – $ for full-text)
Commentaries: Premature babies healthier when parents help with hospital care, study shows – The Guardian (free) AND Preemies Fared Better When Parents Helped with NICU Care – MedPage Today (free registration required) AND Parents’ care can help premature babies in hospital, says study – BBC News (free)
Thu, February 8 – 10 Stories of The Day!
8 Feb, 2018 | 00:15h | UTC
1 – Guideline: Pancreatic cancer in adults: diagnosis and management – National Institute for Health and Care Excellence (free)
News release: Pancreatic cancer patients should be offered early scans to avoid unnecessary surgery, says NICE (free)
2 – Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews – Cochrane Library (free)
Summary: Overview of Cochrane Reviews of interventions used during surgery for preventing surgical site infection (free)
3 – Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: For mortality prediction, qSOFA has poor sensitivity, moderate specificity, review finds – ACP Hospitalist (free) AND Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure assessment for predicting mortality in patients with suspected infection – 2 Minute Medicine (free)
4 – Opinion: This flu season, physicians need to scrap the ‘martyr culture’ of working while sick – STAT (free) (via @CMichaelGibson)
Related study: Working with influenza-like illness: Presenteeism among US health care personnel during the 2014-2015 influenza season – American Journal of Infection Control (link to abstract – $ for full-text) AND Commentaries: Working while sick – ACP Internist (free) AND Health worker survey reveals many work during flu illness – CIDRAP (free)
5 – New cellphone and health studies don’t eliminate uncertainty – Science (free)
Other commentaries: Largest Animal Study of Cell Phone Radiation and Cancer Risk – Medscape (free registration required) AND High doses of cellphone radiation linked to some cancers in rats – STAT (free) AND Cell phone radiation: Could high exposure cause tumors? – Medical News Today (free)
Related Infographic: Date Night with the EHR – NEJM Catalyst (free)
Related Commentary: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free)
Related Guideline: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians(free)
7 – ISPOR 2018 – Top 10 Health Economics and Outcomes Research Trends (free PDF)
Commentary: Top 10 Trends Driving Healthcare in 2018 – NewsWise (free)
8 – Report: Global Monitoring of Disease Outbreak Preparedness: Preventing the Next Pandemics – Harvard Global Health Institute (free PDF)
See also: News Release (free) AND Summary report (free PDF)
9 – Preoperative exercise halves the postoperative complication rate in patients with lung cancer: a systematic review of the effect of exercise on complications, length of stay and quality of life in patients with cancer – British Journal of Sports Medicine (link to abstract – $ for full-text)
Commentaries: Regular exercise halves complication rate after lung cancer surgery – eCancer News (free) AND Lung Cancer Postoperative Complications Reduced With Preoperative Exercise – Pulmonology Advisor (free)
10 – Association of Preoperatively Diagnosed Patent Foramen Ovale With Perioperative Ischemic Stroke – JAMA (free for a period)
Commentaries: PFO Diagnosis Linked With Increased Risk of Perioperative Ischemic Stroke After Noncardiac Surgery – TCTMD (free) AND Preoperatively Diagnosed PFO and Perioperative Stroke – American College of Cardiology, Latest in Cardiology (free)
Tue, February 6 – 10 Stories of The Day!
6 Feb, 2018 | 00:01h | UTC
2 – Viewpoint: Vitamin and Mineral Supplements: What Clinicians Need to Know – JAMA Internal Medicine (free for a period)
3 – Effect of Hot Tea Consumption and Its Interactions With Alcohol and Tobacco Use on the Risk for Esophageal Cancer: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Hot tea tied to higher cancer risk for smokers and drinkers – Reuters (free) AND Very hot tea can raise risk of oesophageal cancer, suggests study – The Guardian (free) AND Hot Tea and Increased Risk for Esophageal Cancer – Medscape (free registration required)
4 – Social exclusion heightens risk of death across many health conditions – NIHR Signal (free)
Original Article: Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis – The Lancet (free) AND Commentary: Inclusion health: addressing the causes of the causes (free) AND Review: What works in inclusion health: overview of effective interventions for marginalised and excluded populations (free registration required)
5 – Risk of pre-eclampsia in women taking metformin: a systematic review and meta-analysis – Diabetic Medicine (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
“Metformin was associated with lower gestational weight gain and a lower risk of pre-eclampsia compared with insulin”
6 – Heparin-Induced Thrombocytopenia in the Patient Who Is Critically Ill – Chest (free)
Source: Critical Care Reviews Newsletter
7 – Richard Smith: Doctors and patients heading in opposite directions – The BMJ Opinion (free)
“Patients increasingly have multiple conditions, while doctors continue remorseless specialisation and subspecialisation. What are the consequences of this divergence?” (via @bmj_latest see Tweet)
Press release: Hydroxyethyl-starch solutions for infusion to be suspended (free)
Source: EMA calls for hydroxyethyl starch solutions to be taken off market – The BMJ News ($)
9 – 5 ways poorly thought out health IT can worsen patient safety – KevinMD.com (free)
10 – Use of social media is associated with short sleep duration in a dose–response manner in students aged 11 to 20 years – Acta Paediatrica (link to abstract – $ for full-text)
Commentary: Social media use linked to lack of sleep in students – Wiley, via EurekAlert (free)
See also a recent Pediatrics supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn (series of free articles) and related articles on Social Media and Mental Health
Research: Catheter Ablation for Atrial Fibrillation with Heart Failure
5 Feb, 2018 | 16:51h | UTCCatheter Ablation for Atrial Fibrillation with Heart Failure – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Catheter ablation better than pharmacological atrial fibrillation therapies – University of Utah Health, via EurekAlert (free)
“In patients w/heart failure & atrial fibrillation, catheter ablation lowers rate of death and hospitalization for worsening HF vs. medical therapy”. (via @NEJM see Tweet)
Early use of tranexamic acid reduces bleeding more effectively
5 Feb, 2018 | 16:51h | UTCEarly use of tranexamic acid reduces bleeding more effectively – NIHR Signal (free)
Original article: Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free) AND Invited Commentary: Tranexamic acid: is it about time? (free)
“It is now clearer that every 15-minute delay after the first hour can reduce survival by about 10%”.
Guideline: Gastrointestinal Complications in Adult Cancer Patients
5 Feb, 2018 | 16:53h | UTCGuideline: Diagnosis and management of gastrointestinal complications in adult cancer patients – German Society of Hematology and Medical Oncology (free)
Research: High performance plasma amyloid-β biomarkers for Alzheimer’s disease
5 Feb, 2018 | 16:48h | UTCHigh performance plasma amyloid-β biomarkers for Alzheimer’s disease – Nature (link to abstract – $ for full-text)
Commentaries: Expert reaction to biomarkers for amyloid-beta in Alzheimer’s disease – Science Media Centre (free) AND A Big Step toward a Blood Test for Alzheimer’s – Scientific American (free) AND Simple blood test spots dementia protein – Nature News (free) AND Alzheimer’s hope as scientists unveil blood test for early signs – The Guardian (free)
AHA Scientific Statement: Cardiovascular Disease and Breast Cancer
5 Feb, 2018 | 16:49h | UTCCommentaries: Breast cancer treatments may increase the risk of heart disease – AHA / ASA Newsroom (free) AND Heart group warns of cardiovascular risks after treatment for breast cancer – STAT (free)
Wed, February 7 – 10 Stories of The Day!
7 Feb, 2018 | 00:01h | UTC
1 – Policy Statement: Recommended Childhood and Adolescent Immunization Schedules: United States, 2018 – American Academy of Pediatrics (free)
The Immunization Schedules for 2018 are available in the Red Book Online (free) and in the Centers for Disease Control and Prevention Website (free)
2 – Rapid Recommendations: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free text and infographics)
3 – Report: E-cigarettes and heated tobacco products: evidence review – Public Health England (free PDF)
News release: PHE publishes independent expert e-cigarettes evidence review (free)
Commentaries: UK experts urge smokers to switch to e-cigs for big health gains – Reuters (free) AND E-cigarettes ‘should be on prescription’ – BBC News (free) AND Doctors should encourage smokers to switch to vaping – OnMedica (free)
See related report recently released by the National Academies of Sciences, Engineering, and Medicine (free report and commentaries)
4 – Effect of an In-Hospital Multifaceted Clinical Pharmacist Intervention on the Risk of Readmission: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Clinical Pharmacist Intervention Can Reduce ED Visits and Hospital Readmissions – MedicalResearch.com (free) AND Pharmacist-led extended medication review and follow-up on discharge may decrease risk of readmission – 2 Minute Medicine (free)
6 – AASLD guidelines for the treatment of hepatocellular carcinoma – Hepatology (free)
7 – Richard Lehman’s journal review, 5 February 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
8 – How Fake Surgery Exposes Useless Treatments – Scientific American (free)
Related: Sham surgeries: A tale of medical reversals & the role of the media – HealthNewsReview (free)
Commentaries: Drug-resistant malaria spreading fast in Southeast Asia – CIDRAP (free) AND Drug-resistant malaria will spread without urgent action, experts warn – The Guardian (free) AND Multidrug resistant malaria spread under the radar for years in Cambodia – Wellcome Sanger Institute (free)
Research: Effects of Preschool in Educational Attainment at 35 Years of Age
5 Feb, 2018 | 16:45h | UTCCommentaries: Longer Early Childhood Intervention Linked To Greater Post-Secondary Attainment – MedicalResearch.com (free) AND Does Preschool Make a Long-Term Difference? – MedPage Today (free) AND Graduates of early childhood program show greater educational gains as adults – EurekAlert (free)
Intravenous antibiotics, administered over 3 hours, are linked to lower death rates in sepsis
5 Feb, 2018 | 16:50h | UTCIntravenous antibiotics, administered over 3 hours, are linked to lower death rates in sepsis – NIHR Signal (free)
Original article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Research: Migraine Associated with Increased Risk of Cardiovascular Diseases
5 Feb, 2018 | 16:47h | UTCMigraine and risk of cardiovascular diseases: Danish population based matched cohort study – The BMJ (free)
Editorial: Migraine and risk of cardiovascular disease (free)
Commentaries: Migraine Associated With Broad Range of CVD Diagnoses in Nationwide Study – TCTMD (free) AND Migraine Linked To Increased Risk of Stroke, AFib, PE and Cardiovascular Disease – MedicalResearch.com (free)
A Revolution in Health Care is Coming
5 Feb, 2018 | 16:27h | UTCA revolution in health care is coming – The Economist (a few articles per month are free) (via @equitylist)
“Welcome to Doctor You”
Research: Prevalence of Pulmonary Embolism in Patients With Syncope
5 Feb, 2018 | 16:46h | UTCPrevalence of Pulmonary Embolism in Patients With Syncope – JAMA Internal Medicine (free for a period)
Author Interview: Prevalence of Pulmonary Embolism in Patients With Syncope (free)
Commentaries: Prevalence of PE Low for Patients Presenting to ER With Syncope – Physician’s Weekly (free) AND Study Finds Pulmonary Embolus Rarely the Cause of Syncope – MedicalResearch.com (free)
Proton Pump Inhibitors: Review of Emerging Concerns
5 Feb, 2018 | 16:23h | UTCProton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free)
Related reviews: Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free)
Related guideline: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)
New Document for Patients: Advanced Health Directive for Dementia
5 Feb, 2018 | 16:26h | UTCOne Day Your Mind May Fade. At Least You’ll Have a Plan – The New York Times (10 articles per month are free)
Free download: Health Directive for Dementia (free PDF) from Advanced Directive for Dementia
Source: New document allows advance planning for dementia – Univadis (free registration required)
“A Simple Way to Document the Medical Care You Would Want If You Had Dementia”
Research: D-dimer Predicts Long-Term Cause-Specific Mortality, Cardiovascular Events and Cancer
5 Feb, 2018 | 16:22h | UTCD-dimer Predicts Long-Term Cause-Specific Mortality, Cardiovascular Events and Cancer in Stable Coronary Heart Disease Patients: The LIPID Study – Circulation (link to abstract – $ for full-text)
Commentary: D-dimer Predicts Long-Term Mortality, Vascular Events, Cancer – American College of Cardiology, Latest in Cardiology (free) AND D-Dimer Predicts CV, Cancer Mortality Over 16 Years in Patients With Stable CHD – Medscape (free registration required)
BSH Guideline: Thrombotic and Haemostatic Issues in Paediatric Malignancy
5 Feb, 2018 | 16:21h | UTC


