Archives
Decreasing the Cost of Care by Avoiding Illness
27 Feb, 2018 | 15:51h | UTCDecreasing the Cost of Care by Avoiding Illness – NEJM Catalyst (free)
Meta-Analysis: Neurocognitive and Educational Outcomes in Children and Adolescents with CKD
27 Feb, 2018 | 15:47h | UTCCommentaries: Analysis finds lower IQ in children with chronic kidney disease – American Society of Nephrology, via ScienceDaily (free) AND CKD Linked to Cognitive Impairment in Kids – MedPage Today (free registration required)
Research: Surprising Rate of Cardiac Amyloidosis in TAVR Patients
27 Feb, 2018 | 15:45h | UTCRelated article: Prevalence of Cardiac Amyloidosis in Patients Referred for Transcatheter Aortic Valve Replacement – Journal of the American College of Cardiology (free)
Research: Bedtime Low Dose Amitriptyline in Chronic Neck Pain
27 Feb, 2018 | 15:44h | UTCRandomized double-blind controlled study of bedtime low dose amitriptyline in chronic neck pain – European Journal of Pain (link to abstract – $ for full-text)
Commentary: Low-dose amitriptyline reduces idiopathic chronic neck pain – Univadis (free registration required)
Opinion: How Value-Based Medicare Payments Exacerbate Health Care Disparities
27 Feb, 2018 | 15:50h | UTCMedical News & Perspectives: How Value-Based Medicare Payments Exacerbate Health Care Disparities – JAMA (free for a limited period)
Oman will raise taxes on tobacco, alcohol, soft drinks and energy drinks by 100%
27 Feb, 2018 | 15:45h | UTC100% excise tax on tobacco, energy drinks from June – MuscatDaily (free) (via @DrFrieden see Tweet)
Oman will raise taxes on tobacco, alcohol, soft drinks and energy drinks by 100%.
Review: Immunotherapy-Induced Colitis
27 Feb, 2018 | 15:42h | UTCImmunotherapy-Induced Colitis: An Emerging Problem for the Hospitalist – Journal of Hospital Medicine (free PDF)
Source: Hospital Medicine Virtual Journal Club
Research: The Effects of Fluoride in the Drinking Water
27 Feb, 2018 | 15:41h | UTCCommentary: Fluoride does not have negative effect on intelligence – News Medical (free)
Mon, February 26 – 10 Stories of The Day!
26 Feb, 2018 | 01:12h | UTC
News release: WHO issues new recommendations calling for accelerated uptake of testing and treatment for TB prevention (free)
2 – ACG Clinical Guideline: Alcoholic Liver Disease – The American Journal of Gastroenterology (free)
Commentary and summary: New Guideline for Management of Alcoholic Liver Disease – NEJM Journal Watch (free for a limited period)
3 – Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning – Nature Biomedical Engineering (link to abstract – $ for full-text) (via @EricTopol see Very interesting Tweet)
Commentaries: Assessing Cardiovascular Risk Factors with Computer Vision – Google Research Blog (free) AND Google’s new AI algorithm predicts heart disease by looking at your eyes – TheVerge (free) AND Combination of AI, eye images could predict cardiovascular disease – Cardiovascular Business (free) AND It’s All in the Eyes: Google AI Calculates Cardiovascular Risk From Retinal Images – Medium (free)
Related guidelines: Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) (free) AND Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)
5 – Opinion: Doctors, Revolt! – The New York Times (free)
“Healing is replaced with treating, caring is supplanted by managing, and the art of listening is taken over by technological procedures. Bernard Lown” (via @lucadf see Tweet)
6 – The global crackdown on parents who refuse vaccines for their kids has begun – VOX (free)
“Countries like Italy and Australia are tired of measles outbreaks — so they’re moving to fine anti-vaccine parents”.
7 – Scientists Aim to Pull Peer Review Out Of The 17th Century – NPR (free)
Related: The Future of Peer Review – Scientific American (free) AND Peer review is a black box. Let’s open it up – STAT News (free) AND Exposing peer review – Research Information (free) AND Researchers debate whether journals should publish signed peer reviews – Science (free) AND The peer-review system for academic papers is badly in need of repair – The Conversation (free)
8 – Antifibrinolytic drugs for treating primary postpartum haemorrhage – Cochrane Library (free)
Related: Updated WHO Recommendation on Tranexamic Acid for the Treatment of Postpartum Haemorrhage (free PDF) AND Early use of tranexamic acid reduces bleeding more effectively – NIHR Signal (free) AND Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free)
Commentary: Spironolactone bests clonidine as fourth drug for resistant hypertension – Univadis (free registration required)
10 – Infant Hospitalizations and Mortality After Maternal Vaccination – Pediatrics (free)
Commentaries: Maternal vaccination during pregnancy not associated with infant hospitalization, mortality – 2 Minute Medicine (free) AND Getting Recommended Vaccines During Pregnancy Doesn’t Lead to Harm in Infants – Physician’s First Watch (free)
Impact of Implementing Antibiotic Stewardship Programs in 15 Small Hospitals
27 Feb, 2018 | 15:40h | UTCImpact of Implementing Antibiotic Stewardship Programs in 15 Small Hospitals: A Cluster-Randomized Intervention – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentary: Intensive, well-resourced antibiotic stewardship found best in small hospitals – CIDRAP (free)
Tue, February 27 – 10 Stories of The Day!
27 Feb, 2018 | 00:56h | UTC
Related guidelines: 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)
2 – Guidelines for Adolescent Depression in Primary Care – American Academy of Pediatrics
Part I. Practice Preparation, Identification, Assessment, and Initial Management (free)
Part II. Treatment and Ongoing Management (free)
Commentary: Pediatricians Call For Universal Depression Screening For Teens – NPR (free)
See also: Guideline for Burn Care Under Austere Conditions: Special Care Topics (free)
Source: Critical Care Reviews Newsletter
News release: Responding to inflight medical emergencies can be stressful for doctors – CMAJ News (free)
Related video: Managing medical emergencies at 36,000 ft: A guide to Air Canada’s in-flight emergency medical kit (free)
Commentaries: 3% rise in deaths for every 10 min delay in restoring blood flow after heart attack – OnMedica (free) AND Treatment Delay and Mortality in STEMI With Shock – American College of Cardiology, Latest in Cardiology (free)
6 – Interventions for paracetamol (acetaminophen) overdose – Cochrane Library (free)
Original article: Interventions for paracetamol (acetaminophen) overdose – Cochrane Library (link to abstract – $ for full-text)
7 – Richard Lehman’s journal review, 26 February 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
8 – FDA Safety Alert: Clarithromycin (Biaxin): Drug Safety Communication – Potential Increased Risk of Heart Problems or Death in Patients With Heart Disease (free)
Commentaries: FDA: Antibiotic Linked to Increased Risk of Death in Heart Disease Patients – MPR (free) AND FDA: Clarithromycin Risks Persist in Patients With CAD – TCTMD (free) FDA Alert: Clarithromycin Risky in Patients With Heart Disease – Medscape (free registration required)
9 – Idiopathic pulmonary fibrosis: pathogenesis and management – Respiratory Research (free)
Related guidelines: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis (free) AND German Guideline for Idiopathic Pulmonary Fibrosis – Update on Pharmacological Therapies 2017 – Pneumologie (free) AND Diagnosis and management of idiopathic pulmonary fibrosis: French practical guidelines – European Respiratory Review (free) AND Idiopathic pulmonary fibrosis in adults: diagnosis and management – NICE (free)
10 – Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients: The PROPER Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Pulmonary Embolism Rule-out Criteria non-inferior to usual care for patients at low-risk for pulmonary embolism – 2 Minute Medicine (free) AND EM Nerd-The Case of the Diagnostic Absurdity (free) AND Using PERC & Sending Home Pulmonary Emboli For Fun and Profit – Emergency Literature of Note (free)
Review: Haemodynamic assessment and support in sepsis and septic shock in resource-limited settings
23 Feb, 2018 | 01:13h | UTCSource: Critical Care Reviews Newsletter
Are you ready for the ATLS 10th Edition Updates?
23 Feb, 2018 | 01:11h | UTCAre you ready for the ATLS 10th Edition Updates? – emDocs (free)
Related: Infographic: ATLS Trauma Update 2018
Guidelines and Review: Management of ARDS in Adults
23 Feb, 2018 | 01:12h | UTCClinical Guidelines Synopsis: Management of ARDS in Adults – JAMA (free)
Related Review: Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment – JAMA (free)
Research: Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty
23 Feb, 2018 | 01:09h | UTCAspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Preventing VTE after Hip or Knee Arthroplasty (free)
“Among patients who received 5 days of rivaroxaban prophylaxis after total hip or total knee arthroplasty, extended prophylaxis with aspirin was not significantly different from rivaroxaban in the prevention of symptomatic venous thromboembolism”.
Fri, February 23 – 10 Stories of The Day!
23 Feb, 2018 | 01:10h | UTC
See also: Commentary: Spontaneous Coronary Artery Dissection: Making strides, long journey ahead! (free) AND Top Ten Things to Know (free PDF)
Commentaries: More data, more answers: picking the optimal antidepressant – The Lancet (free) AND All antidepressants are more efficacious than placebo – OnMedica (free) AND Expert reaction to largest review of antidepressants – Science Media Centre (free) AND Antidepressants can help adults with major depression – The Mental Elf (free)
Commentaries: New rotavirus vaccine to curb child deaths in developing countries – New Zealand Doctor (free) AND Researchers successfully develop a rotavirus vaccine which could benefit millions of children – MedicalXpress (free)
5 – Potential workload in applying clinical practice guidelines for patients with chronic conditions and multimorbidity: a systematic analysis – BMJ Open (free) (via @acpatient and @MaryDixonWoods)
6 – The Origin of Spousal Resemblance for Alcohol Use Disorder – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: For Better or Worse: Risk of Alcohol Use Disorder Rises When Spouse is Diagnosed – Psychiatric News Alert (free) AND Spouses have strong influence on risk for alcohol abuse – Reuters (free)
7 – Cleaning at Home and at Work in Relation to Lung Function Decline and Airway Obstruction – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentaries: Women Who Clean at Home or Work Face Increased Lung Function Decline – American Thoracic Society, via NewsWise (free) AND Cleaning Chemicals ‘Likely Cause Substantial Damage To Women’s Lungs’, Study Finds – Huffpost (free) AND Cleaning at home or work linked to faster lung function decline in women – Univadis (free registration required)
8 – Perspective: Our Other Prescription Drug Problem – New England Journal of Medicine (free)
Related opinion: Benzodiazepines: our other prescription drug epidemic – STAT (free)
9 – Perspective: The Psychology of Clinical Decision Making — Implications for Medication Use – New England Journal of Medicine (free)
Commentary: After-effects not necessarily reduced with robotic prostate surgery – Reuters (free)
Related Cochrane Review with similar results: Laparoscopic and robotic-assisted versus open radical prostatectomy for the treatment of localised prostate cancer – Cochrane Library (free)
Guideline: Perioperative Cardiopulmonary Exercise Testing (CPET)
23 Feb, 2018 | 01:07h | UTC
Potential workload in applying clinical practice guidelines for patients with chronic conditions and multimorbidity
23 Feb, 2018 | 01:08h | UTCPotential workload in applying clinical practice guidelines for patients with chronic conditions and multimorbidity: a systematic analysis – BMJ Open (free) (via @acpatient and @MaryDixonWoods)
Guideline: Peripheral arterial disease: diagnosis and management
23 Feb, 2018 | 01:04h | UTCGuideline: Peripheral arterial disease: diagnosis and management – National Institute for Health and Care Excellence (NICE) (free)
Update on Diabetic Nephropathy
23 Feb, 2018 | 01:02h | UTCUpdate on Diabetic Nephropathy: Core Curriculum 2018 – American Journal of Kidney Diseases (free)
Guideline Synopsis: Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder
23 Feb, 2018 | 01:05h | UTC
Research: Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults
23 Feb, 2018 | 01:03h | UTCCommentaries: Low-Carb And Low-Fat Diets Battle To A Draw – Cardiobrief (free) AND Matching DNA to a diet doesn’t work: ‘We didn’t even come close,’ researcher says – STAT (free) AND Counting Calories Is Not the Key to Weight Loss, New Study Finds – The New York Times (10 articles per month are free) AND Debating low-fat vs low-carb diets? New study found a draw – Scope (free)
Review: Adverse pregnancy outcomes and future maternal cardiovascular disease
23 Feb, 2018 | 01:01h | UTCReview: Adverse pregnancy outcomes and future maternal cardiovascular disease – Clinical Cardiology (free)
Guideline: Heavy menstrual bleeding: assessment and management
23 Feb, 2018 | 01:03h | UTCGuideline: Heavy menstrual bleeding: assessment and management – National Institute for Health and Care Excellence (NICE) (free)
Opinion: It’s poverty, not individual choice, that is driving extraordinary obesity level
23 Feb, 2018 | 00:58h | UTCIt’s poverty, not individual choice, that is driving extraordinary obesity level – The Conversation (free)
“Statistics point remorselessly towards obesity being a symptom with an underlying social cause”.


