Archives
Thu, March 15 – 10 Stories of The Day!
15 Mar, 2018 | 01:50h | UTC
Editorial: Recognizing the Global Impact of Zika Virus Infection during Pregnancy (free)
Quick Take Video Summary: Pregnancy Outcomes after Zika (free)
Commentaries: Study: 7% risk of birth defects in Zika pregnancies – CIDRAP (free) AND Birth defect rate pegged at 7 percent for babies born to Zika-infected women – Reuters (free)
Commentary: Combo Tx Offers New Hope for Cryptococcal Meningitis – MedPage Today (free registration required)
Source: Critical Care Reviews Newsletter
4 – Grader Variability and the Importance of Reference Standards for Evaluating Machine Learning Models for Diabetic Retinopathy – Ophthalmology (link to abstract – $ for full-text)
Commentary: Google’s AI program: Building better algorithms for detecting eye disease – ScienceDaily (free)
5 – Editorial: AI diagnostics need attention – Nature (free) (via @RasoiniR see Tweet)
Related systematic review (just published): Perioperative beta-blockers for preventing surgery-related mortality and morbidity – Cochrane Library (free)
Commentaries: Gout Drug Febuxostat Linked to More CV Deaths Without Uptick in CV Events: CARES Trial – TCTMD (free) AND CARES: Increased Risk of Death With Febuxostat in Patients With Gout and CV Disease – American College of Cardiology (free)
8 – Colonoscopy and Colorectal Cancer Mortality in the Veterans Affairs Health Care System: A Case–Control Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Colonoscopy significantly reduces mortality from colorectal cancer in Veterans Affairs study – 2 Minute Medicine (free) AND Colonoscopy Significantly Reduces CRC Deaths – Medscape (free registration required)
9 – N-Terminal Pro–B-Type Natriuretic Peptide in the Emergency Department – Journal of the Americana College of Cardiology (link to abstract – $ for full-text)
Commentary: NT-proBNP cutpoints validated for diagnosing and ruling out heart failure in the ED – ACP Hospitalist (free)
Related review: BNP in the emergency department: The evidence – First10EM (free)
“In acutely dyspneic patients seen in the ED setting, age-stratified NT-proBNP cutpoints may aid in the diagnosis of acute HF. An NT-proBNP <300 pg/ml strongly excludes the presence of acute HF”.
10 – Sustained Physical Activity, Not Weight Loss, Associated With Improved Survival in Coronary Heart Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: For CHD Patients, Physical Activity More Meaningful Than Weight Changes Over Time – TCTMD (free)
Implementation of the 2017 Berlin Concussion in Sport Group Consensus Statement in contact and collision sports
16 Mar, 2018 | 00:57h | UTC
Wed, March 14 – 10 Stories of The Day!
14 Mar, 2018 | 00:22h | UTC
Related guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association / American Stroke Association (free PDF) AND Summary for ED-relevant care: 2018 AHA/ASA Ischemic Stroke Updates – emDocs (free)
“In routine clinical practice, endovascular treatment for patients with acute ischemic stroke is at least as effective and safe as in the setting of a randomized controlled trial”.
2 – Editorial: Dialysis Modality Survival Comparison: Time to End the Debate, It’s a Tie – American Journal of Kidney Diseases (free)
Related commentary: PD or HD: Which Road Do We Take? – AJKD Blog (free)
Original article: Comparison of Patient Survival Between Hemodialysis and Peritoneal Dialysis Among Patients Eligible for Both Modalities – American Journal of Kidney Diseases (link to abstract – $ for full-text)
Source: Hemodialysis vs. Peritoneal Dialysis for End-Stage Renal Disease – NEJM Journal Watch ($)
Commentaries: Lead and the heart: an ancient metal’s contribution to modern disease – The Lancet Public Health (free) AND Lead exposure may be linked to 412,000 premature US deaths yearly, study says – The Guardian (free) AND Lead and CDV deaths in US adults – Science Media Centre (free) AND Expert reaction to lead and CVD deaths in the US – Science Media Centre (free)
4 – Health Care Spending in the United States and Other High-Income Countries – JAMA (free article, editorials, author interview and video summary)
Commentaries: Why Is U.S. Health Care So Expensive? Some of the Reasons You’ve Heard Turn Out to Be Myths – The New York Times (10 articles per month are free) AND Huge cost of US healthcare driven by drug prices and salaries – The Guardian (free) AND Healthcare: It’s The Prices, Stupid. Isn’t It? – Forbes (free) AND Physician Salaries, Drug Prices Drive High US Health Costs – Medscape (free registration required)
Commentaries: New analysis recommends against using digital rectal exam in primary care – American Academy of Family Physicians, vie EurekAlert (free) AND Little Evidence Supports Use of Digital Rectal Exam – Medscape (free registration required) AND Digital Rectal Exams for Routine Prostate Screening Discouraged – NEJM Physician’s First Watch (free)
See original article and commentaries in our March 12th issue (see #2)
8 – Effects of stress on the development and progression of cardiovascular disease – Nature Reviews Cardiology (free PDF for a limited period) (via @Abraham_RMI)
10 – The 2017 ESC Guidelines on PADs: what’s new? – European Heart Journal (free) AND The ‘Ten Commandments’ of 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases – European Heart Journal (free)
Original Guideline: 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) (free)
Meta-analysis: carbohydrate restriction on glycemic control in adults with diabetes
16 Mar, 2018 | 00:54h | UTCEffect of dietary carbohydrate restriction on glycemic control in adults with diabetes: a systematic review and meta-analysis – Diabetes Research and Clinical Practice (link to abstract – $ for full-text)
“Carbohydrate-restricted diets, associated with reductions in HbA1c of around 0.4% in short term” (via @kamleshkhunti see Tweet)
Tue, March 13 – 10 Stories of The Day!
13 Mar, 2018 | 00:03h | UTC
Key Points: Evaluation and Treatment of Hirsutism in Premenopausal Women – JAMA Clinical Guidelines Synopsis (free for a limited period)
2 – #ACC18 – Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops – New England Journal of Medicine (free for a limited period)
Commentaries: Barbershop-Based Intervention Leads to Blood Pressure Reductions in African-American Men – American College of Cardiology (free) AND Mixing Haircuts and Hypertension Rx a ‘Home Run’ for Blood Pressure Control – TCTMD (free)
“Among black male barbershop patrons with uncontrolled hypertension, health promotion by barbers resulted in larger blood-pressure reduction when coupled with medication management in barbershops by specialty-trained pharmacists”.
3 – #ACC18 – 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (SMART-DATE): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: SMART-DATE: Myocardial Infarction Risk Higher with Six-Month Versus Twelve-Month DAPT – American College of Cardiology (free) AND Too Soon for 6-Month DAPT, Say SMART-DATE Investigators, Despite Positive Trial – TCTMD (free)
Related Guidelines: 2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy (free) AND 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)
4 – #ACC18 – Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care – American College of Cardiology (free) AND Low-Dose, Three-Drug Polypill TRIUMPHs for Blood Pressure – TCTMD (free)
5 – Viewpoint: Big Data and Machine Learning in Health Care – JAMA (free for a limited period)
6 – Aromatherapy Versus Oral Ondansetron for Antiemetic Therapy Among Adult Emergency Department Patients: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentaries: Practice Changing: Inhaled Isopropyl Alcohol Superior to Oral Ondansetron as an Antiemetic – NEJM Journal Watch (free) AND Wake Up And Smell the Isopropyl – Emergency Medicine Literature of Note (free)
7 – Do Antidepressants Work? – The New York Times (10 articles per month are free)
“The most comprehensive study on them has recently been published, showing mostly modest effects”.
See related meta-analysis and commentaries in our February 23rd issue (see #3)
8 – Richard Lehman’s journal reviews, 12 March 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
“Wake me up when there is a positive randomized trial of vitamin D pills for anything” (from Richard Lehman’s review, see above).
Commentary: Dengue fever linked to increased risk of stroke – CMAJ, via ScienceDaily (free)
Mon, March 12 – 10 Stories of The Day!
12 Mar, 2018 | 01:34h | UTC
#ACC18 – Highlights from the American College of Cardiology’s 67th Annual Scientific Session
Commentaries: Survival benefit seen for some patients when cardiologists are away at academic conferences – Harvard Medical School, via ScienceDaily (free) AND TCT paradox: Patients more likely to survive MI during interventional cardiology conference – Cardiovascular Business (free)
Related study: Mortality and Treatment Patterns Among Patients Hospitalized With Acute Cardiovascular Conditions During Dates of National Cardiology Meetings – JAMA Internal Medicine (free)
“The study’s release date is particularly timely considering another major conference—the American College of Cardiology’s Scientific Session—kicks off this weekend”. (from Cardiovascular Business)
2 – #ACC18 – The ODYSSEY Trial Ends Well— But Will It Be Enough? – Cardiobrief (free) AND Ten Quick Thoughts on ODYSSEY – John Mandrola, via Medscape (free registration required)
“An absolute risk reduction of 1.6% in the primary endpoint translates to a number needed to treat of 64. Using the current price of $14,500 per year, Kaul calculated that preventing one event over the trial period of almost 3 years would cost about $2.6 million” (via John Mandrola). This study was presented at #ACC18 and has not been published yet. Among the many commentaries, these two were selected for a balanced point of view.
3 – #ACC18 – Carvedilol for Prevention of Chemotherapy Related Cardiotoxicity – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Beta Blocker Shows Mixed Results in Protecting Against Chemo-Induced Heart Damage – American College of Cardiology (free) AND Carvedilol Effect in Preventing Chemotherapy Induced CardiotoxicitY – CECCY – American College of Cardiology (free)
Related study from #ACC18: Heart Drugs Prevented Cardiotoxicity in Breast Cancer Treated With Anthracycline and Trastuzumab – American College of Cardiology (free)
“According to the CECCY trial, carvedilol had no effect on left ventricular function in breast cancer patients treated w/ doxorubicin, but did result in a reduction in troponin I levels & diastolic dysfunction”. (via @ACCinTouch see Tweet)
4 – #ACC18 – Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome: The SECURE-PCI Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Lipid Lowering in Acute Coronary Syndrome: Is Treatment Early Enough? (free for a limited period)
Commentaries: Statins Evaluation in Coronary Procedures and Revascularization – SECURE-PCI – American College of Cardiology (free) AND No Benefits Likely with Very Early Statins in ACS Patients – MedPage Today (free registration required) AND SECURE-PCI Comes Up Short for Statin Preloading in ACS Patients – TCTMD (free)
5 – #ACC18 – Hospital Readmission After Perioperative Acute Myocardial Infarction Associated With Noncardiac Surgery – Circulation (free PDF for a limited period)
Commentaries: Hospital Readmissions After Perioperative AMI – American College of Cardiology, Latest in Cardiology (free) AND Perioperative MIs Bring Too Many Patients Back to the Hospital After Noncardiac Surgery – TCTMD (free)
6 – #ACC18 – Big Swings in Daily Temperatures Linked to Spikes in MI Rates – TCTMD (free) AND Heart Attacks Often Follow Extreme Temperature Changes – Cardiosmart (free) AND Outdoor Temperature Swings Tied to STEMI Uptick – Medscape (free registration required) AND Dramatic swings in temperature linked to significantly more heart attacks – News Medical (free)
7 – #ACC18 – Inflammatory Bowel Disease Increases Likelihood of a Heart Attack – American College of Cardiology (free) AND Inflammatory bowel disease may raise heart attack risk – Medical News Today (free) AND Those with IBD twice as likely to have heart attack – Cardiovascular Business (free) AND Inflammatory Bowel Disease Makes Heart Attack Twice as Likely – Cardiosmart (free)
8 – #ACC18 – Getting flu shot halves death risk for heart failure patients – Cardiovascular Business (free) AND Flu Vaccine Reduces Mortality, Hospitalization in HF Patients: Meta-analysis – TCTMD (free) AND Flu Shot Cuts Risk for Death by Half in Heart Failure – Medscape (free registration required) AND Getting Flu Vaccine Cuts Risk of Death by Half in People with Heart Failure – American College of Cardiology (free)
This meta-analysis of observational studies suggests a possible benefit.
9 – #ACC18 – Aspirin Lowers Risk of Death for Patients with Diabetes, Heart Failure – American College of Cardiology (free) AND Aspirin Linked to Lower Mortality in Diabetes With Heart Failure – Medscape (free registration required) AND ACC 2018: Aspirin Lowers Risk of Death in Patients With Diabetes and Heart Failure – PracticeUpdate (free registration required)
10 – #ACC18 – MANAGE: Reduced Mortality and Cardiovascular Events in MINS Patients Receiving Dabigatran – American College of Cardiology (free) AND MANAGE Suggests Dabigatran Could Be Useful for Treating Myocardial Injury After Noncardiac Surgery – TCTMD (free)
“One expert called the trial results “provocative” but said its methods were “muddy,” making the findings difficult to interpret” (from TCTMD)
ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
8 Mar, 2018 | 22:32h | UTCCommentary: Major Medical Associations Feud Over Diabetes Guidelines – NPR (free)
“Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with type 2 diabetes”
Fri, March 9 – 10 Stories of The Day!
9 Mar, 2018 | 00:04h | UTC
1 – The Tobacco Atlas, Sixth Edition (free PDF)
News Release: Big tobacco is targeting the world’s most vulnerable to increase profits – American Cancer Society (free)
See companion website: TobaccoAtlas.org
Related: Explore the GBD tool to compare tobacco risks globally – IHME (free interactive tool)
Commentary with key points to remember: European Position Paper on Spontaneous Coronary Artery Dissection – American College of Cardiology, Latest in Cardiology (free)
Related position statement: Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association – Circulation (free)
Related: Aortic Dissection and Aortic Aneurysms Associated with Fluoroquinolones: A Systematic Review and Meta-Analysis – American Journal of Medicine (free) AND Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study – BMJ Open (free) AND Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone – JAMA Internal Medicine (free)
4 – Graduate students need more mental health support, new study highlights – Science (free) AND Mental Health Crisis for Grad Students – Inside Higher Ed (free) AND Depression, anxiety high in graduate students, survey shows – University of Texas Health Science Center, via ScienceDaily (free)
5 – Case report: Self-Management of an Inferior ST-Segment Elevation Myocardial Infarction – New England Journal of Medicine (free)
6 – Maintenance proton pump inhibition therapy and risk of oesophageal cancer – Cancer Epidemiology (link to abstract – $ for full-text)
Commentary: Long-term PPI Use and Increased Esophageal CA Risk – Medscape (free registration required)
Related studies suggesting a link with gastric cancer: Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text) AND Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden – BMJ Open (free)
This observational study suggests a possible link.
7 – Metformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age; follow-up of two RCTs – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Diabetes drug use during pregnancy linked to child’s weight – The Endocrine Society, via ScienceDaily (free) AND Diabetes drug use during pregnancy affects child’s weight – OnMedica (free) AND Metformin in Pregnancy May Increase Childhood Obesity Risk – Medscape (free registration required)
8 – EVOLVE: The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question – Internal Medicine Journal (free) (via @RSiemieniuk)
See other lists of low-value practices in Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Another interesting list of commonly used low-value practices that should be questioned.
9 – Inflammatory Bowel Disease Increases Likelihood of a Heart Attack – American College of Cardiology (free) AND Inflammatory bowel disease may raise heart attack risk – Medical News Today (free) AND Those with IBD twice as likely to have heart attack – Cardiovascular Business (free)
Commentary: Probiotics and fish oil in pregnancy may reduce allergies in children – NHS Choices (free) AND Diet During Pregnancy May Cut Offspring Allergy Risk – MedPage Today (free registration required) AND Probiotics and Fish Oil During Pregnancy May Curb Allergies in Kids – The New York Times (10 articles per month are free)
Guideline: Treatment of infections caused by multidrug-resistant Gram-negative bacteria
8 Mar, 2018 | 22:33h | UTCTreatment of infections caused by multidrug-resistant Gram-negative bacteria: report of the British Society for Antimicrobial Chemotherapy/Healthcare Infection Society/British Infection Association Joint Working Party – Journal of Antimicrobial Chemotherapy (free) (via @ABsteward)
Novel subgroups of adult-onset diabetes and their association with outcomes
8 Mar, 2018 | 22:29h | UTCNovel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: 5 Classifications of Diabetes Proposed – Physician’s First Watch (free) AND Should diabetes be divided into 5 categories to improve treatment? – Cardiovascular Business (free) AND Diabetes Consists of Five Types, Not Two, Say Researchers – Medscape (free registration required)
New Guide to Infection Control in The Hospital
8 Mar, 2018 | 22:31h | UTCNew Guide to Infection Control in The Hospital – International Society for Infectious Diseases (free)
A free, online resource on the principles and interventions needed to reduce healthcare associated infections, with suggested control measures across different resource levels.
Meta-Analysis: Drug treatment effects on outcomes in heart failure with preserved ejection fraction
8 Mar, 2018 | 22:30h | UTCEditorial: Pharmacological strategies in heart failure with preserved ejection fraction: time for an individualised treatment strategy? (free)
Commentary: Heartbeat: Is there any effective therapy for heart failure with preserved ejection fraction? (free)
In this meta-analysis of RCT testing treatments for patients with heart failure with preserved ejection fraction, only beta-blockers demonstrated reductions in all-cause and cardiovascular mortality.
Clinical Practice Guideline: Hoarseness
8 Mar, 2018 | 22:28h | UTCSee also: Executive Summary
2018 AHA/ASA Ischemic Stroke Updates
8 Mar, 2018 | 22:26h | UTCSummary for ED-relevant care: 2018 AHA/ASA Ischemic Stroke Updates – emDocs (free)
Original guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)
The Challenge of Doctor-Patient Relations in the Internet Age
8 Mar, 2018 | 22:27h | UTCThe Challenge of Doctor-Patient Relations in the Internet Age – The New York Times (10 articles per month are free)
Related: E-patients hold key to the future of healthcare – The BMJ Opinion (free)
One-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV
8 Mar, 2018 | 22:24h | UTCOne-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV – National Institute of Allergy and Infectious Diseases (free) (via @iasociety see Tweet)
Related: New ways to fight HIV and tuberculosis emerge at AIDS conference – Science (free)
The Tobacco Atlas, Sixth Edition
8 Mar, 2018 | 22:21h | UTCThe Tobacco Atlas, Sixth Edition (free PDF)
News Release: Big tobacco is targeting the world’s most vulnerable to increase profits – American Cancer Society (free)
See companion website: TobaccoAtlas.org
Related: Explore the GBD tool to compare tobacco risks globally – IHME (free interactive tool)
Research: Fluoroquinolone use and risk of aortic aneurysm and dissection
8 Mar, 2018 | 22:17h | UTCFluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study – The BMJ (free)
Related: Aortic Dissection and Aortic Aneurysms Associated with Fluoroquinolones: A Systematic Review and Meta-Analysis – American Journal of Medicine (free) AND Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study – BMJ Open (free) AND Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone – JAMA Internal Medicine (free)
Proton pump inhibition therapy and risk of oesophageal cancer
8 Mar, 2018 | 22:14h | UTCMaintenance proton pump inhibition therapy and risk of oesophageal cancer – Cancer Epidemiology (link to abstract – $ for full-text)
Commentary: Long-term PPI Use and Increased Esophageal CA Risk – Medscape (free registration required)
Related studies suggesting a link with gastric cancer: Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text) AND Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden – BMJ Open (free)
This observational study suggests a possible link.
ESC position paper on spontaneous coronary artery dissection
8 Mar, 2018 | 22:19h | UTCCommentary with key points to remember: European Position Paper on Spontaneous Coronary Artery Dissection – American College of Cardiology, Latest in Cardiology (free)
Related position statement: Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association – Circulation (free)
Self-Management of an Inferior ST-Segment Elevation Myocardial Infarction
8 Mar, 2018 | 22:15h | UTCCase report: Self-Management of an Inferior ST-Segment Elevation Myocardial Infarction – New England Journal of Medicine (free)
Graduate students need more mental health support
8 Mar, 2018 | 22:16h | UTCGraduate students need more mental health support, new study highlights – Science (free) AND Mental Health Crisis for Grad Students – Inside Higher Ed (free) AND Depression, anxiety high in graduate students, survey shows – University of Texas Health Science Center, via ScienceDaily (free)
Research: Metformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age
8 Mar, 2018 | 22:13h | UTCMetformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age; follow-up of two RCTs – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Diabetes drug use during pregnancy linked to child’s weight – The Endocrine Society, via ScienceDaily (free) AND Diabetes drug use during pregnancy affects child’s weight – OnMedica (free) AND Metformin in Pregnancy May Increase Childhood Obesity Risk – Medscape (free registration required)
The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question
8 Mar, 2018 | 22:12h | UTCEVOLVE: The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question – Internal Medicine Journal (free) (via @RSiemieniuk)
See other lists of low-value practices in Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Another interesting list of commonly used low-value practices that should be questioned.
Research: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality
8 Mar, 2018 | 22:07h | UTCEffect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: One-off PSA screening for prostate cancer does not save lives – eCancer News (free)
“Largest ever prostate cancer trial – CAP – published in the JAMA. No effect from low intensity PSA screening on prostate cancer mortality at 10 years”. (via @KariTikkinen see Tweet)