Archives
Research: Aromatherapy Versus Oral Ondansetron for Antiemetic Therapy
16 Mar, 2018 | 03:29h | UTCAromatherapy Versus Oral Ondansetron for Antiemetic Therapy Among Adult Emergency Department Patients: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentaries: Practice Changing: Inhaled Isopropyl Alcohol Superior to Oral Ondansetron as an Antiemetic – NEJM Journal Watch (free) AND Wake Up And Smell the Isopropyl – Emergency Medicine Literature of Note (free)
Panic, chronic anxiety and burnout: doctors at breaking point
16 Mar, 2018 | 03:30h | UTCPanic, chronic anxiety and burnout: doctors at breaking point – The Guardian (free)
Research: Vitamin D and risk of total and site specific cancers
16 Mar, 2018 | 03:26h | UTC“Wake me up when there is a positive randomized trial of vitamin D pills for anything” (from Richard Lehman’s review).
Richard Lehman’s journal reviews – 12 March 2018
16 Mar, 2018 | 03:28h | UTCRichard Lehman’s journal reviews, 12 March 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Research: Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention
16 Mar, 2018 | 03:22h | UTC#ACC18 – Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome: The SECURE-PCI Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Lipid Lowering in Acute Coronary Syndrome: Is Treatment Early Enough? (free for a limited period)
Commentaries: Statins Evaluation in Coronary Procedures and Revascularization – SECURE-PCI – American College of Cardiology (free) AND No Benefits Likely with Very Early Statins in ACS Patients – MedPage Today (free registration required) AND SECURE-PCI Comes Up Short for Statin Preloading in ACS Patients – TCTMD (free)
Research: Risk of stroke in patients with dengue fever
16 Mar, 2018 | 03:24h | UTCCommentary: Dengue fever linked to increased risk of stroke – CMAJ, via ScienceDaily (free)
Acute Myocardial Infarction Mortality During Dates of National Interventional Cardiology Meetings
16 Mar, 2018 | 03:23h | UTCCommentaries: Survival benefit seen for some patients when cardiologists are away at academic conferences – Harvard Medical School, via ScienceDaily (free) AND TCT paradox: Patients more likely to survive MI during interventional cardiology conference – Cardiovascular Business (free)
Related study: Mortality and Treatment Patterns Among Patients Hospitalized With Acute Cardiovascular Conditions During Dates of National Cardiology Meetings – JAMA Internal Medicine (free)
“The study’s release date is particularly timely considering another major conference—the American College of Cardiology’s Scientific Session—kicks off this weekend”. (from Cardiovascular Business)
Research: Inflammatory Bowel Disease Linked to Increased Risk in Heart Attack
16 Mar, 2018 | 03:18h | UTC#ACC18 – Inflammatory Bowel Disease Increases Likelihood of a Heart Attack – American College of Cardiology (free) AND Inflammatory bowel disease may raise heart attack risk – Medical News Today (free) AND Those with IBD twice as likely to have heart attack – Cardiovascular Business (free) AND Inflammatory Bowel Disease Makes Heart Attack Twice as Likely – Cardiosmart (free)
Meta-analysis: Getting flu shot may reduce deaths in heart failure
16 Mar, 2018 | 03:16h | UTC#ACC18 – Getting flu shot halves death risk for heart failure patients – Cardiovascular Business (free) AND Flu Vaccine Reduces Mortality, Hospitalization in HF Patients: Meta-analysis – TCTMD (free) AND Flu Shot Cuts Risk for Death by Half in Heart Failure – Medscape (free registration required) AND Getting Flu Vaccine Cuts Risk of Death by Half in People with Heart Failure – American College of Cardiology (free)
This meta-analysis of observational studies suggests a possible benefit.
Research: Hospital Readmission After Perioperative Acute Myocardial Infarction Associated With Noncardiac Surgery
16 Mar, 2018 | 03:20h | UTC#ACC18 – Hospital Readmission After Perioperative Acute Myocardial Infarction Associated With Noncardiac Surgery – Circulation (free PDF for a limited period)
Commentaries: Hospital Readmissions After Perioperative AMI – American College of Cardiology, Latest in Cardiology (free) AND Perioperative MIs Bring Too Many Patients Back to the Hospital After Noncardiac Surgery – TCTMD (free)
Research: Aspirin Lowers Risk of Death for Patients with Diabetes, Heart Failure
16 Mar, 2018 | 03:15h | UTC#ACC18 – Aspirin Lowers Risk of Death for Patients with Diabetes, Heart Failure – American College of Cardiology (free) AND Aspirin Linked to Lower Mortality in Diabetes With Heart Failure – Medscape (free registration required) AND ACC 2018: Aspirin Lowers Risk of Death in Patients With Diabetes and Heart Failure – PracticeUpdate (free registration required)
Fri, March 16 – 10 Stories of The Day!
16 Mar, 2018 | 02:54h | UTC
1 – Mapping child growth failure in Africa between 2000 and 2015 – Nature (free)
Invited commentary, by Kofi Annan: Data can help to end malnutrition across Africa (free)
Other commentaries: Africa ‘very, very far away’ from meeting global target to end child malnutrition – The Guardian (free) Local Burden of Disease – Child Growth Failure – IHME (free) AND Zooming in on advances and opportunities – IHME (free)
2 – Guideline: Attention deficit hyperactivity disorder: diagnosis and management – National Institute for Health and Care Excellence (NICE) (free)
3 – State of The Art Review: Pulmonary arterial hypertension: pathogenesis and clinical management – The BMJ (free for a limited period)
Related Guidelines: Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults – CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free)
4 – Very interesting resource: A Visual introduction to the basic concepts of probability theory – Seeing Theory (free) (via @CochraneUK see Tweet)
Commentaries: High Cardiovascular Fitness in Midlife Tied to Lower Dementia Risk Later – NEJM Physician’s First Watch (free) AND Physically fit women nearly 90 percent less likely to develop dementia – American Academy of Neurology, via ScienceDaily (free)
6 – Like It Or Not, Personal Health Technology Is Getting Smarter – NPR (free)
“Nice article about wearables related issues, such as medicalization of the healthy, privacy loss, low adherence, uncertain reliability of measurements and uncertain health benefits”. (via @RasoiniR see Tweet)
Related: Get Ready For A Tsunami Of ECGs – Cardiobrief (free) AND: Thoughts on the Apple Watch and Mobile ECG, by Dr John Mandrola (free) AND Overdiagnosis Only a Matter of Time With ECG Watches – Medscape (free registration required)
8 – Panic, chronic anxiety and burnout: doctors at breaking point – The Guardian (free)
9 – Statement: American Diabetes Association® Deeply Concerned About New Guidance from American College of Physicians Regarding Blood Glucose Targets for People with Type 2 Diabetes (free)
See original guideline and commentary: ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
10 – Calcium and vitamin D supplementation and increased risk of serrated polyps: results from a randomised clinical trial – Gut (link to abstract – $ for full-text)
Commentaries: Calcium and vitamin D supplements may raise risk of polyps – MedicalNewsToday (free) AND Calcium Supplements Up Risk for Precancerous Serrated Polyps – Medscape (free registration required)
See related meta-analysis of RCT showing calcium and vitamin D don’t prevent bone fractures
Research: Low-level lead exposure and mortality in US adults
16 Mar, 2018 | 02:43h | UTCCommentaries: Lead and the heart: an ancient metal’s contribution to modern disease – The Lancet Public Health (free) AND Lead exposure may be linked to 412,000 premature US deaths yearly, study says – The Guardian (free) AND Lead and CDV deaths in US adults – Science Media Centre (free) AND Expert reaction to lead and CVD deaths in the US – Science Media Centre (free)
Guidelines for Aneurysmal Subarachnoid Hemorrhage
16 Mar, 2018 | 02:41h | UTC
Research: Health Care Spending in the United States and Other High-Income Countries
16 Mar, 2018 | 02:41h | UTCHealth Care Spending in the United States and Other High-Income Countries – JAMA (free article, editorials, author interview and video summary)
Commentaries: Why Is U.S. Health Care So Expensive? Some of the Reasons You’ve Heard Turn Out to Be Myths – The New York Times (10 articles per month are free) AND Huge cost of US healthcare driven by drug prices and salaries – The Guardian (free) AND Healthcare: It’s The Prices, Stupid. Isn’t It? – Forbes (free) AND Physician Salaries, Drug Prices Drive High US Health Costs – Medscape (free registration required)
Guideline Summary: Peripheral Arterial Diseases
16 Mar, 2018 | 02:42h | UTCThe 2017 ESC Guidelines on PADs: what’s new? – European Heart Journal (free) AND The ‘Ten Commandments’ of 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases – European Heart Journal (free)
Original Guideline: 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) (free)
Meta-Analysis: Dialysis Modality Survival Comparison
16 Mar, 2018 | 02:40h | UTCEditorial: Dialysis Modality Survival Comparison: Time to End the Debate, It’s a Tie – American Journal of Kidney Diseases (free)
Related commentary: PD or HD: Which Road Do We Take? – AJKD Blog (free)
Original article: Comparison of Patient Survival Between Hemodialysis and Peritoneal Dialysis Among Patients Eligible for Both Modalities – American Journal of Kidney Diseases (link to abstract – $ for full-text)
Source: Hemodialysis vs. Peritoneal Dialysis for End-Stage Renal Disease – NEJM Journal Watch ($)
Research: 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome
16 Mar, 2018 | 02:29h | UTC#ACC18 – 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (SMART-DATE): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: SMART-DATE: Myocardial Infarction Risk Higher with Six-Month Versus Twelve-Month DAPT – American College of Cardiology (free) AND Too Soon for 6-Month DAPT, Say SMART-DATE Investigators, Despite Positive Trial – TCTMD (free)
Related Guidelines: 2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy (free) AND 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)
A Visual introduction to the basic concepts of probability theory
16 Mar, 2018 | 02:39h | UTCVery interesting resource: A Visual introduction to the basic concepts of probability theory – Seeing Theory (free) (via @CochraneUK see Tweet)
Review: Pulmonary arterial hypertension
16 Mar, 2018 | 02:38h | UTCState of The Art Review: Pulmonary arterial hypertension: pathogenesis and clinical management – The BMJ (free for a limited period)
Related Guidelines: Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults – CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free)
Review: Effects of stress on the development and progression of cardiovascular disease
16 Mar, 2018 | 02:26h | UTCEffects of stress on the development and progression of cardiovascular disease – Nature Reviews Cardiology (free PDF for a limited period) (via @Abraham_RMI)
Chronic kidney disease and arrhythmias
16 Mar, 2018 | 02:27h | UTC
Guideline: Evaluation and Treatment of Hirsutism in Premenopausal Women
16 Mar, 2018 | 02:28h | UTCKey Points: Evaluation and Treatment of Hirsutism in Premenopausal Women – JAMA Clinical Guidelines Synopsis (free for a limited period)
Meta-Analysis: Digital Rectal Examination for Prostate Cancer Screening in Primary Care
16 Mar, 2018 | 02:26h | UTCCommentaries: New analysis recommends against using digital rectal exam in primary care – American Academy of Family Physicians, vie EurekAlert (free) AND Little Evidence Supports Use of Digital Rectal Exam – Medscape (free registration required) AND Digital Rectal Exams for Routine Prostate Screening Discouraged – NEJM Physician’s First Watch (free)
Research: Endovascular treatment for acute ischaemic stroke in routine clinical practice
16 Mar, 2018 | 02:25h | UTCRelated guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association / American Stroke Association (free PDF) AND Summary for ED-relevant care: 2018 AHA/ASA Ischemic Stroke Updates – emDocs (free)
“In routine clinical practice, endovascular treatment for patients with acute ischemic stroke is at least as effective and safe as in the setting of a randomized controlled trial”.


