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Review: Management of Barrett’s Esophagus with Low-grade Dysplasia

23 Apr, 2018 | 20:47h | UTC

Management of Barrett’s esophagus with low-grade dysplasia – Diseases of the Esophagus (free)

 


Research: Machine Learning Algorithms for the Prediction of Outcomes in Heart Failure Patients

23 Apr, 2018 | 19:59h | UTC

Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients – Journal of the American Heart Association (free for a limited period)

Commentary: Big data analysis accurately predicts patient survival from heart failure – MedicalXpress (free)

 


Perspective: To Defeat Superbugs, Everyone Will Need Access to Clean Water

23 Apr, 2018 | 20:01h | UTC

To defeat superbugs, everyone will need access to clean water – The Conversation (free) (via @Onisillos)

 


Research: Blood Biomarkers in Traumatic Brain Injuries

23 Apr, 2018 | 20:04h | UTC

Plasma metabolomic biomarkers accurately classify acute mild traumatic brain injury from controls – PLOS One (free)

Commentary: Blood biomarkers may allow easier detection, confirmation of concussions – University of California, Irvine, via EurekAlert (free)

 


Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI

23 Apr, 2018 | 16:47h | UTC

Safety and efficacy of dual vs. triple antithrombotic therapy in patients with atrial fibrillation following percutaneous coronary intervention: a systematic review and meta-analysis of randomized clinical trials – European Heart Journal (free)

Compared with triple antithrombotic therapy, dual antithrombotic therapy shows a reduction in TIMI major or minor bleeding by 47% with comparable outcomes of major adverse cardiac events.

 


EuroPrevent 2018 Research: Exercise After a Heart Attack Could Save Your Life

23 Apr, 2018 | 16:46h | UTC

Exercise after a heart attack — it could save your life, research suggests – European Society of Cardiology, via ScienceDaily (free)

Other commentaries: Regular exercise after heart attack might halve risk of death over next few years – OnMedica (free) AND It’s not too late: Exercise after heart attack cuts mortality risk – Cardiovascular Business (free) AND Remaining Active After MI May Help Stave Off Mortality – TCTMD (free)

“Becoming more physically active after a myocardial infarction halves the risk of dying within 4 years, study finds”

 


Perspective: Why Do We Need Vaccines?

23 Apr, 2018 | 16:42h | UTC

Why do we need vaccines? – Welcome Trust (free) (via @greg_folkers)

 


ASCO Guideline Update: Fertility Preservation in Patients With Cancer

23 Apr, 2018 | 16:39h | UTC

Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)

Commentary: ASCO Clinical Practice Guideline Update: Fertility Preservation in Patients With Cancer – The ASCO Post (free)

Related guidelines: Fertility preservation for patients with gynecologic malignancies: The Korean Society for Fertility Preservation clinical guidelines – Clinical and Experimental Reproductive Medicine (free) AND Fertility preservation for medical reasons in girls and women: British fertility society policy and practice guideline – Human Fertility (free)

 


New U.S. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV

23 Apr, 2018 | 16:41h | UTC

Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV – AIDSInfo (free)

 


Perspective: Pasta Is Good For You, Say Scientists Funded By Big Pasta

23 Apr, 2018 | 16:42h | UTC

Pasta Is Good For You, Say Scientists Funded By Big Pasta – BuzzFeed News (free)

 


Mon, April 23 – 10 Stories of The Day!

23 Apr, 2018 | 00:04h | UTC

 

1 – Report: WHO Expert Consultation on Rabies – World Health Organization (free)

News release: WHO publishes new rabies guidelines and recommendations on lifesaving immunization (free)

 

2 – Simplifying the use of prognostic information in traumatic brain injury – Journal of Neurosurgery

Part 1: The GCS-Pupils score: an extended index of clinical severity (free)

Part 2: Graphical presentation of probabilities (free)

Commentaries: New Glasgow Coma Scale–Pupils Score and Multifactor Probability Outcome Charts for Use in Patients with TBI – Journal of Neurosurgery, via NewsWise (free) AND New scoring system will speed up assessment of brain injuries – OnMedica (free) AND Glasgow Coma Scale Gets an Eye-Opening Update – Medscape (free registration required)

 

3 – Revised SAGE recommendation on use of dengue vaccine – World Health Organization (free)

Commentaries: A new dengue vaccine should only be used in people who were previously infected, WHO says – Science (free) AND WHO recommends testing before use of Sanofi’s dengue vaccine – Reuters (free)

 

4 – Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition – Cephalalgia (free PDF) (via @adamcifu)

News release and website: The International Classification of Headache Disorders 3rd edition (free)

Commentary: International Classification of Headache Disorders – The Lancet Neurology (free)

 

5 – Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder – Bipolar Disorders (free)

Related Guideline: Bipolar disorder: assessment and management – National Institute for Health and Care Excellence (free)

 

6 – Diagnosis and Management of Primary Aldosteronism: the Endocrine Society guideline 2016 revisited – European Journal of Endocrinology (free)

 

7 – Review: Hypokalemia: a clinical update – Endocrine Connections (free)

 

8 – Role of Immunotherapy in the Treatment of Asthma – Agency for Healthcare Research and Quality (free)

Source: EvidenceAlerts

 

9 – Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial – JAMA (free)

Editorial: Nitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis – JAMA (free)

 

10 – Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study – American Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Intranasal Esketamine Found Effective in Rapid Reduction of Depression, Suicidal Thoughts – Psychiatric News Alert (free) AND Fast-acting benefits of ketamine for depression and suicidality – American Psychiatric Association, via ScienceDaily (free) AND Ketamine ‘shows promise’ in treating depression – OnMedica (free) AND Ketamine Spray Effective for Suicidality, but Abuse Concerns Linger – Medscape (free registration required)

Related: ‘Cautious Optimism’ Marks Outlook for Ketamine, Mood Disorders – Psychiatric News (free)

 


Meta-Analysis: Cognitive Outcomes of Children Born Extremely or Very Preterm

23 Apr, 2018 | 16:36h | UTC

Cognitive Outcomes of Children Born Extremely or Very Preterm Since the 1990s and Associated Risk Factors: A Meta-analysis and Meta-regression – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: Preemies and underweight babies more likely to have low IQs – Reuters (free) AND Despite Advancing Neonatal Health, Preterm Babies Still Risk Cognitive Impairment – MedicalResearch.com (free)

 


Meta-Analysis: Sleep Duration and Incidence of Obesity in Infants, Children, and Adolescents

23 Apr, 2018 | 16:34h | UTC

Sleep duration and incidence of obesity in infants, children, and adolescents: a systematic review and meta-analysis of prospective studies – Sleep (link to abstract – $ for full-text)

Commentary: Lack of Sleep leads to Obesity in Children and Adolescents – University of Warwick (free)

 


Meta-Analysis: Association of Cannabis With Cognitive Functioning in Adolescents and Young Adults

20 Apr, 2018 | 01:57h | UTC

Association of Cannabis With Cognitive Functioning in Adolescents and Young Adults: A Systematic Review and Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Marijuana’s effects on young brains diminish 72 hours after use, research says – CNN (free) AND ‘Poorer Cognitive Functioning’ of Marijuana Users Detailed in New Study – Inverse (free)

 


Cohort Study: Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality

20 Apr, 2018 | 02:02h | UTC

Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality – New England Journal of Medicine (free)

Editorial: The Value in an Ambulatory Blood-Pressure Registry (free)

Commentaries: Value of Ambulatory BP Monitoring Bolstered by Large Study – TCTMD (free) AND 24-hour ambulatory BP measurements strongly predict mortality – The Hospitalist (free) AND Expert reaction to study looking at blood pressure measurement method and predicting risk of heart disease – Science Media Centre (free)

 


Randomized Trial of Normothermic Preservation in Liver Transplantation

20 Apr, 2018 | 01:56h | UTC

A randomized trial of normothermic preservation in liver transplantation – Nature (free PDF for a limited period)

Commentaries: Room temperature liver storage technique improves transplant success – University of Oxford (free) AND Keeping livers ‘alive’ boosts transplant success, trial finds – BBC (free) AND A ‘breakthrough in organ preservation’: Study shows keeping livers warm helps preserve them for transplant – STAT (free)

 


Report: Trends in Future Health Financing and Coverage

20 Apr, 2018 | 01:55h | UTC

Trends in future health financing and coverage: future health spending and universal health coverage in 188 countries, 2016–40 – The Lancet (free)

Commentaries: New Study Finds People Covered by Universal Health Coverage Will Fall Far Below UN Sustainable Development Goal – Institute for Health Metrics and Evaluation (free)

 


Guideline: Management of Acute Coronary Syndromes

20 Apr, 2018 | 01:53h | UTC

Management of Acute Coronary Syndromes – Diabetes Canada Clinical Practice Guidelines Expert Committee (free)

Source: Critical Care Reviews Newsletter

 


Research :Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia

20 Apr, 2018 | 01:57h | UTC

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia – New England Journal of Medicine (free)

Editorial: Gene Therapy as a Curative Option for β-Thalassemia (free)

Quick Take Video Summary: LentiGlobin Gene Therapy for β-Thalassemia (free)

Commentaries: Gene therapy could free some people from a lifetime of blood transfusions – MIT Technology Review (free) AND Gene Therapy For Inherited Blood Disorder Reduced Transfusions – NPR (free) AND Expert reaction to study on gene therapy for beta-thalassaemia – Science Media Centre (free)

 


Review: Pediatric Minor Head Injury

20 Apr, 2018 | 01:52h | UTC

Pediatric Minor Head Injury 2.0: Moving from Injury Exclusion to Risk Stratification – Emergency Medicine Clinics of North America (free)

 


Choosing Wisely: “Top 12” Recommendations That Are Reducing Overuse

20 Apr, 2018 | 01:50h | UTC

The “Top 12” Recommendations That Are Reducing Overuse – Choosing Wisely (free) (via @kennylinafp)

Learn more about the Choosing Wisely Initiative and see other lists of low-value practices in Choosing Wisely U.S. / Choosing Wisely UKChoosing Wisely Australia AND Choosing Wisely Canada

 


Multimorbidity: A Priority for Global Health Research

20 Apr, 2018 | 01:49h | UTC

Report: Multimorbidity: a priority for global health research – The Academy of Medical Sciences (free) (via @equitylist)

News Release: Global burden of multiple serious illnesses must be urgently addressed (free)

Commentaries: Burden of patients with multiple diseases could sink health systems around the world, warn medical experts – Independent (free) AND People with multiple health conditions get raw deal, says report – OnMedica (free)

See also: related articles on the Caring for High-Need, High-Cost Patients (free reports, articles and commentaries)

 


Choosing Wisely Campaigns: A Work in Progress

20 Apr, 2018 | 01:50h | UTC

Choosing Wisely Campaigns: A Work in Progress – JAMA (free for a limited period) (via @ChooseWiselyCA  see Tweet)

 


Guideline: Recommended Standard Care for People with Suicide Risk

20 Apr, 2018 | 01:47h | UTC

Recommended Standard Care for People with Suicide Risk: Making Health Care Suicide Safe – National Action Alliance for Suicide Prevention (free PDF)

News Release: New Recommended Standard Care for People with Suicide Risk Aims to Fundamentally Improve Suicide Care Delivered Nationwide (free PDF)

Commentary: First-Ever Suicide Prevention Recommendations Released – Medscape (free registration required)

 


Debate on the Value of Sytematic Reviews and Meta-analyses

20 Apr, 2018 | 01:45h | UTC

Debate on systematic reviews and meta-analyses: (via @trished)

Viewpoint 1: Are systematic reviews and meta-analyses still useful research? We are not sure – Intensive Care Medicine (free)

Viewpoint 2: Are systematic reviews and meta-analyses still useful research? Yes (free)

 


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