Archives
Randomized Controlled Trial: Home vs Hospital Treatment of COPD Exacerbation
24 Apr, 2018 | 18:01h | UTCSource: Hospital Medicine Virtual Journal Club
Systematic Review: Antifibrinolytics for Heavy Menstrual Bleeding
24 Apr, 2018 | 17:58h | UTCAntifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)
“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)
Expert Analysis: Major Dyslipidemia Guidelines and Their Discrepancies
24 Apr, 2018 | 17:58h | UTC
FDA Approves Rapid Diagnostic Test for Candida Auris
24 Apr, 2018 | 17:57h | UTCFDA approves rapid diagnostic test for Candida auris – CIDRAP (free)
FDA News Release: FDA authorizes new use of test, first to identify the emerging pathogen Candida auris (free)
Related: Tracking Candida auris – CDC (free)
Review: The Vasculature in Prediabetes
24 Apr, 2018 | 17:59h | UTCThe Vasculature in Prediabetes – Circulation Research (free for a limited period) (via @Abraham_RMI)
Tue, April 24 – 10 Stories of The Day!
24 Apr, 2018 | 01:43h | UTC
1 – World Immunization Week, 24-30 April 2018 – World Health Organization (free resources)
2 – The vaccine dilemma: how experts weigh benefits for many against risks for a few – STAT (free)
3 – Why do we need vaccines? – Welcome Trust (free) (via @greg_folkers)
Other commentaries: Regular exercise after heart attack might halve risk of death over next few years – OnMedica (free) AND It’s not too late: Exercise after heart attack cuts mortality risk – Cardiovascular Business (free) AND Remaining Active After MI May Help Stave Off Mortality – TCTMD (free)
“Becoming more physically active after a myocardial infarction halves the risk of dying within 4 years, study finds”
“Compared with triple antithrombotic therapy, dual antithrombotic therapy shows a reduction in major or minor bleeding by 47% with comparable outcomes of major adverse cardiac events”.
See also: Related Physician Tools and Materials (free clinician summary, slides and more)
Commentaries: New guideline: Start taking MS drugs early on – American Academy of Neurology, via EurekAlert (free) AND New MS Guideline Addresses Starting, Switching, and Stopping Disease-modifying Therapy – MD Magazine (free) AND Start MS Drugs Early, New Guideline Says – MedPage Today (free registration required)
8 – Richard Lehman’s journal review, 23 April 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
9 – State of the Art Review: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications – The BMJ (free for a limited period)
Commentary: Commonly prescribed heartburn drug linked to Pneumonia in Older Adults – University of Exeter (free)
Related: Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free) AND Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)
Source: Hospital Medicine Virtual Journal Club
2018 Guidelines for the Management of Patients with Bipolar Disorder
23 Apr, 2018 | 21:19h | UTCRelated Guideline: Bipolar disorder: assessment and management – National Institute for Health and Care Excellence (free)
Guideline: Diagnosis and Management of Primary Aldosteronism
23 Apr, 2018 | 21:17h | UTCDiagnosis and Management of Primary Aldosteronism: the Endocrine Society guideline 2016 revisited – European Journal of Endocrinology (free)
Hypokalemia: A Clinical Update
23 Apr, 2018 | 21:16h | UTCHypokalemia: a clinical update – Endocrine Connections (free)
New International Classification of Headache Disorders
23 Apr, 2018 | 21:14h | UTCHeadache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition – Cephalalgia (free PDF) (via @adamcifu)
News release and website: The International Classification of Headache Disorders 3rd edition (free)
Commentary: International Classification of Headache Disorders – The Lancet Neurology (free)
Randomized Trial: 5-Day Nitrofurantoin vs Single-Dose Fosfomycin in Uncomplicated Lower UTI
23 Apr, 2018 | 21:13h | UTCEditorial: Nitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis – JAMA (free)
Report: WHO Expert Consultation on Rabies
23 Apr, 2018 | 21:10h | UTCWHO Expert Consultation on Rabies – World Health Organization (free)
News release: WHO publishes new rabies guidelines and recommendations on lifesaving immunization (free)
Report: Role of Immunotherapy in the Treatment of Asthma
23 Apr, 2018 | 21:15h | UTCRole of Immunotherapy in the Treatment of Asthma – Agency for Healthcare Research and Quality (free)
Source: EvidenceAlerts
Revised WHO Recommendation on Use of Dengue Vaccine
23 Apr, 2018 | 21:12h | UTCRevised SAGE recommendation on use of dengue vaccine – World Health Organization (free)
Commentaries: A new dengue vaccine should only be used in people who were previously infected, WHO says – Science (free) AND WHO recommends testing before use of Sanofi’s dengue vaccine – Reuters (free)
New Glasgow Coma Scale–Pupils Score
23 Apr, 2018 | 21:10h | UTCSimplifying the use of prognostic information in traumatic brain injury – Journal of Neurosurgery
Part 1: The GCS-Pupils score: an extended index of clinical severity (free)
Part 2: Graphical presentation of probabilities (free)
Commentaries: New Glasgow Coma Scale–Pupils Score and Multifactor Probability Outcome Charts for Use in Patients with TBI – Journal of Neurosurgery, via NewsWise (free) AND New scoring system will speed up assessment of brain injuries – OnMedica (free) AND Glasgow Coma Scale Gets an Eye-Opening Update – Medscape (free registration required)
Dutch Guideline for Clinical Foetal-neonatal and Paediatric Post-mortem Radiology
23 Apr, 2018 | 21:05h | UTC
Randomized Controlled Trial: Ketamine for Rapid Reduction of Symptoms of Depression and Suicidality
23 Apr, 2018 | 21:08h | UTCEfficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Intranasal Esketamine Found Effective in Rapid Reduction of Depression, Suicidal Thoughts – Psychiatric News Alert (free) AND Fast-acting benefits of ketamine for depression and suicidality – American Psychiatric Association, via ScienceDaily (free) AND Ketamine ‘shows promise’ in treating depression – OnMedica (free) AND Ketamine Spray Effective for Suicidality, but Abuse Concerns Linger – Medscape (free registration required)
Related: ‘Cautious Optimism’ Marks Outlook for Ketamine, Mood Disorders – Psychiatric News (free)
Research: Real-World Implementation of Video Outpatient Consultations
23 Apr, 2018 | 21:06h | UTC
Infographics: Global Infections by the Numbers
23 Apr, 2018 | 21:02h | UTCGlobal Infections by the Numbers – Scientific American (free)
Review: Lower Extremity Traumatic Amputations
23 Apr, 2018 | 21:04h | UTCSource: Critical Care Reviews Newsletter
UK Man with ‘Worst Ever’ Drug-Resistant Gonorrhea Is Now Cured
23 Apr, 2018 | 21:00h | UTCUK Man with ‘Worst Ever’ Drug-Resistant Gonorrhea Is Now Cured – LiveScience (free)
Other commentaries: ‘World’s worst’ super-gonorrhoea man cured – BBC (free) AND Successful Treatment in UK Very Resistant Gonorrhea Case – Medscape (free registration required) AND Highly resistant gonorrhea case treated successfully with ertapenem – Outbreak News Today (free)
See related report: Multi-drug resistant gonorrhoea in England (free PHE report and commentaries)
Perspective: Time Out — Charting a Path for Improving Performance Measurement
23 Apr, 2018 | 21:03h | UTCTime Out — Charting a Path for Improving Performance Measurement – New England Journal of Medicine (free)
Report: Drugs for the Management of Rheumatoid Arthritis
23 Apr, 2018 | 21:00h | UTCSource: EvidenceAlerts
Research: Management of Fever in Africa
23 Apr, 2018 | 20:58h | UTCCommentaries: Study on fever in children in Africa may change global guidelines – Karolinska Institutet (free) AND Trials in Africa support conditional day 3 follow-up for children with fever – PLOS, via EurekAlert (free)
Pancreatitis: Pearls & Pitfalls
23 Apr, 2018 | 20:59h | UTCPancreatitis: Pearls & Pitfalls – emDocs (free)
Related guidelines: American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis – Gastroenterology (free) AND Clinical practice guideline: management of acute pancreatitis – Canadian Journal of Surgery (free)


