Archives
Opinion: Conflicting Evidence on Health Effects of Salt Reduction Calls for a Redesign of Guidelines
16 May, 2018 | 00:42h | UTC
Randomized Trial: Intracutaneously vs. Transcutaneously Sutured Ileostomy to Prevent Stoma-related Complications
16 May, 2018 | 00:41h | UTC
Perspective: Surgical Checklists Save Lives — but Once in a While, They Don’t. Why?
16 May, 2018 | 00:40h | UTCSurgical Checklists Save Lives — but Once in a While, They Don’t. Why? – The New York Times (10 articles per month are free)
Meta-Analysis: Transcranial Magnetic Stimulation for Stroke Survivors
16 May, 2018 | 00:38h | UTCCommentaries: For Stroke Victims, Brain Magnetic Stimulation Leads to Improved Walking Speed – Wolters Kluwer, via NewsWise (free) AND Stroke survivors may benefit from magnetic brain stimulation – Medical News Today (free)
Meta-Analysis: Domperidone for Increasing Breast Milk in Mothers of Premature Babies
16 May, 2018 | 00:37h | UTCDomperidone for increasing breast milk volume in mothers expressing breast milk for their preterm infants: a systematic review and meta‐analysis – BJOG (link to abstract – $ for full-text)
Commentaries: Domperidone increases breast milk production in mothers of premature babies – NIHR Signals (free) AND Domperidone can boost breast milk supply – here’s what you need know – The Conversation (free) AND Domperidone tied to modest increase in breast milk supply – MedicalXpress (free)
Cross-Sectional Study: Living Near Farms Linked to Lower Prevalence of Atopy
16 May, 2018 | 00:38h | UTCResidential proximity to livestock farms is associated with a lower prevalence of atopy – Occupational & Environmental Medicine (link to abstract – $ for full-text)
Commentaries: Living near a farm could help prevent allergies – UPI (free) AND Atopy less common in adults living near a livestock farm – OnMedica (free) AND Just living close to livestock might lower allergy risk – Reuters (free)
Retrospective Cohort: Achieved Systolic BP and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
16 May, 2018 | 00:35h | UTCEffect of Achieved Systolic Blood Pressure on Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus: A Population-Based Retrospective Cohort Study – Diabetes Care (link to abstract – $ for full-text)
Commentaries: Diabetics with lower achieved SBP may be at greater risk for cardiovascular disease – Cardiovascular Business (free) AND No reduced CVD risk for SBP <120 mm hg in type 2 diabetes – MedicalXpress (free)
Study: Testing Blood Donations for Zika Virus is Costly and Finds Few Infections
15 May, 2018 | 09:36h | UTCInvestigational Testing for Zika Virus among U.S. Blood Donors – New England Journal of Medicine (free)
Quick Take Video Summary: Testing Blood Donations for Zika Virus (free)
Sounding Board: Revisiting Blood Safety Practices Given Emerging Data about Zika Virus (free)
Commentaries: Study: Zika blood donation screening costly, finds few cases – CIDRAP (free) AND Testing for Zika virus in blood donors finds few infections — at a cost of about $5.3 million each – STAT (free)
Randomized Trial: 5-Year Outcomes of Hybrid Revascularization in Selected Patients with Multivessel Disease
16 May, 2018 | 00:36h | UTCHybrid Coronary Revascularization in Selected Patients With Multivessel Disease: 5-Year Clinical Outcomes of the Prospective Randomized Pilot Study – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)
Commentaries: Hybrid Revascularization: 5-Year Outcomes – American College of Cardiology (free)
Wed, May 16 – 10 Stories of The Day!
16 May, 2018 | 00:04h | UTC
1 – News Release: First-ever WHO list of essential diagnostic tests to improve diagnosis and treatment outcomes (free) (via @Onisillos)
Executive summary: List of Essential In Vitro Diagnostics, First edition (2018) – World Health Organization (free PDF)
News release: Study by center for health security identifies characteristics of microorganisms most likely to cause a global pandemic (free)
Commentaries: Is this the face of Disease X? The deadly pathogens which could cause the next global pandemic – The Telegraph (free) AND The Next Deadly Pandemic Could Be Unlike Any Threats We Know, Say Experts – Science Alert (free) AND The Next Pandemic: Forget Zika Or Ebola, Airborne Viruses Like The Flu And The Common Cold Are The Real Threat – Inquisitr (free) AND Report: Next Pandemic Will Likely Be Respiratory-Based Virus – MedPage Today (free registration required)
Related: Are we prepared for the looming epidemic threat? (free commentaries and video)
3 – Position Paper: Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories – Obesity Reviews (free)
Commentary: Some calories more harmful than others – University of California, via EurekAlert (free)
4 – Review: Diagnostic workup, etiologies and management of acute right ventricle failure – Intensive Care Medicine (free for a limited period)
Source: Critical Care Reviews Newsletter
5 – Improving Prediction of Dementia in Primary Care – Annals of Family Medicine (free)
Commentaries: Screening Tool Improves Dementia Prediction – Medscape (free registration required) AND Visual Test Could Help Predict Dementia Risk in Elders – NEJM Physician’s First Watch (free)
Commentaries: Biomarkers, PET imaging may predict cognitive decline en route to Alzheimer’s – Health Imaging (free) AND Amyloid PET Scan Can Predict Progression to Alzheimer’s in Patients With Mild Cognitive Impairment – MedicalResearch.com (free)
Related Studies: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and free commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free full-text and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and free commentaries)
7 – Last Month in Oncology with Dr. Bishal Gyawali: April 2018 – eCancer News (free)
8 – Effect of Intravesical Instillation of Gemcitabine vs Saline Immediately Following Resection of Suspected Low-Grade Non–Muscle-Invasive Bladder Cancer on Tumor Recurrence: SWOG S0337 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Intravesical Gemcitabine Therapy Cuts Bladder Cancer Recurrence – MPR (free) AND Simple post-surgery step reduces bladder cancer recurrence – SWOG, via EurekAlert (free)
9 – Drug-eluting stents versus bare-metal stents in saphenous vein grafts: a double-blind, randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary: Outcomes similar with DES vs. BMS in saphenous vein graft lesions – Healio (free registration required)
10 – Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA (free for a limited period)
Related Reviews: Optimizing post‐polypectomy surveillance: A practical guide for the endoscopist – Digestive Endoscopy (free) AND Optimal Colonoscopy Surveillance Interval after Polypectomy – Clinical Endoscopy (free)
Related Guidelines: Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer (free) AND Korean Guidelines for Postpolypectomy Colonoscopy Surveillance – Digestive Endoscopy (free) AND Colorectal cancer surveillance after index colonoscopy: Guidance from the Canadian Association of Gastroenterology (free) AND Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline (free)
Advanced adenomas are associated with subsequent increased risk for colorectal cancer, but nonadvanced adenomas don’t seem to be associated with increased risk.
AHA Advice for Patients: Are BP Measurement Mistakes Making You Chronically Ill?
15 May, 2018 | 12:37h | UTCAre blood pressure measurement mistakes making you chronically ill? – American Heart Association News (free text and infographic)
Commentary: BP measurement: you’re probably doing it wrong – Univadis (free registration required)
Case–Control Study: Smoking and Risk of Ischemic Stroke in Young Men
14 May, 2018 | 18:03h | UTCSmoking and Risk of Ischemic Stroke in Young Men – Stroke (link to abstract – $ for full-text)
Commentaries: Even young men who smoke have increased stroke risk – Reuters (free) AND Number of Cigarettes Smoked per Day Influences Stroke Risk in Young Men – TCTMD (free) AND Men younger than 50: the more you smoke, the more you stroke – AHA/ASA Newsroom (free)
Randomized Trial: Restrictive vs. Liberal Fluids for Major Abdominal Surgery
15 May, 2018 | 05:05h | UTCEditorial: Finding the Right Balance (free)
Commentaries: Restrictive fluids tied to kidney injury after major abdominal surgery – MDedge (free) AND Restricting Fluids During Abdominal Surgery Shows No Benefit, Possible Renal Risk – Medscape (free registration required)
Meta-Analysis: Corticosteroids Reduce Risk of Death Within 28 Days in Severe Alcoholic Hepatitis
15 May, 2018 | 03:04h | UTCCorticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo—a Meta-analysis of Individual Data – Gastroenterology (link to abstract – $ for full-text)
Commentary: Severe alcoholic hepatitis: corticosteroids alone are best for short-term survival – Univadis (free registration required)
Tue, May 15 – 10 Stories of The Day!
15 May, 2018 | 01:28h | UTC
1 – News Release: WHO plan to eliminate industrially-produced trans-fatty acids from global food supply – World Health Organization (free)
See also: REPLACE Action package: Trans Fat Free by 2023 – World Health Organization (free resources)
Commentaries: Editorial Board Opinion: The World Doesn’t Need Trans Fats – The New York Times (10 articles per month are free) AND WHO calls for trans fats to be eliminated within five years – Reuters (free) AND Industrial trans fats must be removed from food supply, WHO says – The Guardian (free) AND The new global plan to eliminate the most harmful fat in food, explained – VOX (free)
2 – Experimental vaccine to be used against Ebola outbreak in the DRC – STAT (free)
Related: WHO to send vaccines to fight new Ebola outbreak – NBC News (free) AND The New Ebola Outbreak Could Take ‘Three, Maybe Four’ Months to Control – The Atlantic (free)
See also: WHO News: Ebola Outbreak Declared in Democratic Republic of the Congo (free news release and commentaries)
3 – Complete Revascularization During Primary Percutaneous Coronary Intervention Reduces Death and Myocardial Infarction in Patients With Multivessel Disease: Meta-Analysis and Meta-Regression of Randomized Trials – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)
Commentary: Complete Revascularization During PCI for Multivessel STEMI – American College of Cardiology (free)
Related: Meta-Analysis of Culprit-Only vs Multivessel PCI in Patients with STEMI and Multivessel Coronary Disease (link to abstract, commentaries and Cochrane Review on the subject)
4 – The Burnout Crisis in American Medicine – The Atlantic (free)
Related: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free) AND Panic, chronic anxiety and burnout: doctors at breaking point – The Guardian (free) AND To Care Is Human — Collectively Confronting the Clinician-Burnout Crisis – New England Journal of Medicine (free) AND Beyond Burnout — Redesigning Care to Restore Meaning and Sanity for Physicians – New England Journal of Medicine (free)
5 – Richard Lehman’s journal review, 14 May 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
6 – Perspective: Deployment of Preventive Interventions — Time for a Paradigm Shift – New England Journal of Medicine (free)
8 – Guideline: Deprescribing benzodiazepine receptor agonists – Canadian Family Physician (free) (via @Deprescribing)
Related: CaDeN Deprescribing Guidelines and Algorithms (free) AND 11 Drugs You Should Seriously Consider Deprescribing – Medscape Slideshow (free registration required) AND Current and future perspectives on the management of polypharmacy – BMC Family Practice (free)
9 – NAP6 Report: Anaesthesia, Surgery and Life-Threatening Allergic Reactions: Report and findings of the Royal College of Anaesthetists’ 6th National Audit Project (free PDF)
News Release: RCoA undertakes largest ever study of anaphylaxis in anaesthesia and surgery (free)
Infographic: Anaesthesia, Surgery and Life-Threatening Allergic Reactions (free PDF)
“The study found teicoplanin is 17-fold more likely to cause anaphylaxis than penicillin and similar drugs. As 90 per cent of patients who report penicillin allergy are in fact not allergic, better identification of true allergy would reduce risk”. (from News Release)
10 – Guideline: Screening for impaired vision in community-dwelling adults aged 65 years and older in primary care settings – Canadian Task Force on Preventive Health Care (free)
See also: Summary of recommendations for clinicians and policy-makers (free)
Commentaries: Screening for impaired vision in older adults: New Canadian guideline – Canadian Medical Association Journal, via EurekAlert (free) AND Canadian Guideline Recommends Against Vision Screening of Older Adults in Primary Care Settings – NEJM Physician’s First Watch (free)
FDA Safety Alert: Neurovascular Stents in the Treatment of Unruptured Brain Aneurysms
14 May, 2018 | 11:57h | UTCNeurovascular Stents Used for Stent-Assisted Coiling (SAC): Letter to Health Care Providers – Recommendations Associated With the Use of These Devices in the Treatment of Unruptured Brain Aneurysms – U.S. Food & Drug Administration (free)
Commentary: FDA Cautions on Stents for Unruptured Brain Aneurysms – NEJM Physician’s First Watch (free) AND FDA issues safety alert on stents used in aneurysm coiling – Univadis (free registration required)
Meta-Analysis: Adding Vasopressin to Catecholamine Vasopressors May Lower AF in Distributive Shock
14 May, 2018 | 15:04h | UTCAssociation of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Vasopressin plus catecholamines lowers risk of atrial fibrillation in distributive shock – 2 Minute Medicine (free) AND Vasopressin Lowers Sepsis Afib Risk – MedPage Today (free registration required)
Cross-Sectional Study: Prevalence and Risk Factors for Taenia Solium Cysticercosis in School-aged Children in China
14 May, 2018 | 10:05h | UTCCommentary: Reducing tapeworm infection could improve academic performance, reduce poverty – Stanford University, via EurekAlert (free)
Cluster-Randomized, Crossover Study: Continuous Glucose Monitoring for Glycemic Control in ICU Patients
14 May, 2018 | 11:30h | UTCNear-Continuous Glucose Monitoring Makes Glycemic Control Safer in ICU Patients – Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Hypoglycemia reduced with continuous glucose monitoring in small trial of ICU patients – ACP Diabetes (free)
Cluster-Randomized Trial: Breastfeeding During Infancy and Neurocognitive Function in Adolescence
14 May, 2018 | 13:09h | UTCCommentary: Breast-Feeding Has No Impact on I.Q. by Age 16 – The New York Times (10 articles per month are free)
Study: 6-Minute Walk Test Helps Predict Postoperative Cognitive Dysfunction After Heart Surgery
14 May, 2018 | 09:34h | UTCPreoperative 6-Minute Walk Distance Is Associated With Postoperative Cognitive Dysfunction – The Annals of Thoracic Surgery (link to abstract – $ for full-text)
Commentaries: 6-minute walk test predicts cognitive problems after heart surgery – Cardiovascular Business (free) AND Simple walking test helps predict risk for cognitive issues after heart surgery – Elservier, via EurekAlert (free)
NIHR Signals: New Nursing Collection
14 May, 2018 | 07:03h | UTCNursing Collection – NIHR Signals (free)
“Ahead of #InternationalNursesDay, we asked three nurses what research matters to them and why the findings need to be shared” (via @NIHR_DC see Tweet)
Short Review: Essential Tremor
14 May, 2018 | 05:51h | UTCClinical Pearl: Essential Tremor – NEJM Resident 360 (free)
Mon, May 14 – 10 Stories of The Day!
14 May, 2018 | 00:11h | UTC
Editorial: Finding the Right Balance (free)
Commentaries: Restrictive fluids tied to kidney injury after major abdominal surgery – MDedge (free) AND Restricting Fluids During Abdominal Surgery Shows No Benefit, Possible Renal Risk – Medscape (free registration required)
2 – Investigational Testing for Zika Virus among U.S. Blood Donors – New England Journal of Medicine (free)
Quick Take Video Summary: Testing Blood Donations for Zika Virus (free)
Sounding Board: Revisiting Blood Safety Practices Given Emerging Data about Zika Virus (free)
Commentaries: Study: Zika blood donation screening costly, finds few cases – CIDRAP (free) AND Testing for Zika virus in blood donors finds few infections — at a cost of about $5.3 million each – STAT (free)
3 – Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo—a Meta-analysis of Individual Data – Gastroenterology (link to abstract – $ for full-text)
Commentary: Severe alcoholic hepatitis: corticosteroids alone are best for short-term survival – Univadis (free registration required)
4 – Advice for Patients: Are blood pressure measurement mistakes making you chronically ill? – American Heart Association News (free text and infographic)
Commentary: BP measurement: you’re probably doing it wrong – Univadis (free registration required)
5 – Oral Antibiotic Exposure and Kidney Stone Disease – Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentaries: Study suggests oral antibiotics may increase kidney stone risk – CIDRAP (free) AND Antibiotics May Raise the Risk for Kidney Stones – The New York Times (free) AND Oral Antibiotics May Raise Risk of Kidney Stones – Children’s Hospital of Philadelphia, via NewsWise (free)
6 – Viewpoint: Management Reasoning: Beyond the Diagnosis – JAMA (free for a limited Period)
7 – Association of Efficacy of Resistance Exercise Training With Depressive Symptoms: Meta-analysis and Meta-regression Analysis of Randomized Clinical Trials – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Resistance Exercise Might Improve Depression Symptoms – NEJM Physician’s First Watch (free) AND Resistance exercise may reduce depressive symptoms in adults – MedicalXpress (free) AND Resistance Exercise Training May Alleviate Some Depressive Symptoms – MedicalResearch.com (free)
8 – Global statistics on alcohol, tobacco and illicit drug use: 2017 status report – Addiction (free PDF)
Commentaries: Alcohol and tobacco are by far the biggest threat to human welfare of all addictive drugs – Society for the Study of Addiction, via ScienceDaily (free) AND Which drugs pose the biggest threat to public health? – Medical News Today (free)
9 – Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents – assessment of adverse events in non-randomised studies – Cochrane Library (link to abstract – $ for full-text)
“Our findings suggest that methylphenidate may be associated with a number of serious adverse events as well as a large number of non-serious adverse events in children and adolescents, which often lead to withdrawal of methylphenidate”.
10 – Cost-effectiveness of Electroconvulsive Therapy vs Pharmacotherapy/Psychotherapy for Treatment-Resistant Depression in the United States – JAMA Psychiatry (free for a limited period)
Author interview: Cost-effectiveness of Electroconvulsive Therapy for Treatment-Resistant Depression in the United States (free)
Commentaries: Study about ‘shock therapy’ for depression suggests more patients should try it sooner – Michigan Medicine – University of Michigan, via EurekAlert (free) AND Third-Line Electroconvulsive Therapy May Be Best for Patients With Treatment-Resistant Depression – Psychiatric News Alert (free) AND ECT Found Cost Effective Early in Depression Treatment – MedPage Today (free registration required)
Study: Financial Conflicts of Interest Among Authors of Urology Guidelines
14 May, 2018 | 04:49h | UTC“59% Urology Guideline writers received payments from companies AND 37% provided inaccurate COIs forms” (via @daviesbj see Tweet)


