Archives
Perspective: The Adverse Impact of the Physician-Hero
6 Jun, 2018 | 21:38h | UTCThe Adverse Impact of the Physician-Hero – NEJM Catalyst (free)
Perspective: The Terrifying Lessons of a Pandemic Simulation
6 Jun, 2018 | 21:36h | UTCThe Terrifying Lessons of a Pandemic Simulation – The New Yorker (free)
Review: Perimesencephalic Hemorrhage
6 Jun, 2018 | 21:35h | UTCPerimesencephalic Hemorrhage: A Review of Epidemiology, Risk Factors, Presumed Cause, Clinical Course, and Outcome – Stroke (free for a limited period)
ASCO 2018: Matching Treatment to Genetic Changes in the Tumor Improves Survival Across Multiple Cancer Types
6 Jun, 2018 | 21:31h | UTC
Updates in the Evaluation and Management of Breast Cancer
6 Jun, 2018 | 21:27h | UTCUpdates in the Evaluation and Management of Breast Cancer – Mayo Clinic Proceedings (free)
Tue, June 5 – 10 Stories of The Day!
5 Jun, 2018 | 00:01h | UTC
News Release: More active people for a healthier world: The global action plan on physical activity 2018 – 2030 (free resources)
News Release: Commission calls for urgent action against chronic diseases (free)
3 – #ASCO18 – PREOPANC-1 Trial Compares Preoperative Chemoradiotherapy vs Immediate Surgery for Pancreatic Cancer – The ASCO Post (free)
Related Video: Pre-operative chemotherapy with radiation may help people with pancreatic cancer live longer – eCancer News (free)
4 – #ASCO18 – Adjuvant mFOLFIRINOX vs Gemcitabine in Resected Pancreatic Cancer – The ASCO Post (free)
Related: Pancreatic Cancer Survival Jumps With Postsurgical Chemo Combo – OncLive (free) AND Study Finds Rare Gain for Tough-To-Treat Pancreatic Cancer – Associated Press (free)
5 – Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders – JAMA Neurology (free for a limited period)
Commentaries: Hepatitis C guideline recommends screening for all people born 1945-1975 – CMAJ, via EurekAlert (free) AND Canadian Group Offers New Guidelines on Hepatitis C Screening, Management – NEJM Physician’s First Watch (free)
Related Guidelines: HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C – American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) (free) AND EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
8 – Richard Lehman’s journal review, 4 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Source: Critical Care Reviews Newsletter
10 – Eliminating Inappropriate Telemetry Monitoring: An Evidence-Based Implementation Guide – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Continuing to Improve Appropriateness of Continuous Electrocardiographic Monitoring (Telemetry) (free for a limited period)
Review: Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
6 Jun, 2018 | 21:26h | UTC
Research: Venous Thromboembolism Prophylaxis Overused in Hospitalized Patients
6 Jun, 2018 | 21:25h | UTCUse of Venous Thromboembolism Prophylaxis in Hospitalized Patients – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Study: Hospitals Overuse VTE Prophylaxis – MedPage Today (free registration required) AND Excess venous thromboembolism prophylaxis common among low-, high-risk patients – Healio (free registration required) AND Venous Thromboembolism Prophylaxis Over & Underutilized in Some Hospitalized Patients – MedicalResearch.com (free)
Wed, June 6 – 10 Stories of The Day!
6 Jun, 2018 | 00:52h | UTC
Commentary: Antibiotics Weren’t Used to Cure These Patients. Fecal Bacteria Were – The New York Times (10 articles per month are free) AND The Latest Poop On Fecal Transplants Vs. Antibiotics For C. Difficile Diarrhea – Forbes (free)
2 – Association of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Study Supports Metformin Use at eGFRs as Low as 30 – NEJM Physician’s First Watch (free) AND Metformin safe for most diabetics with kidney disease – UPI (free) AND Evidence Growing Metformin Safe in Many With Diabetes and CKD – Medscape (free registration required)
Related Studies: Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease (link to abstract and commentaries) AND Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF – ACP Diabetes Monthly (free)
3 – #ASCO18 – Video (35 min): ASCO 2018 conference round up, by Dr Bishal Gyawali and Will Davies (free)
4 – #ASCO18 – Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer – New England Journal of Medicine (free)
Editorial: Endocrine Adjuvant Therapy for Localized Breast Cancer (free)
Commentary: Aromatase Inhibitor Plus Ovarian Suppression Yields Benefit in High-Risk Premenopausal Patients With Breast Cancer – The ASCO Post (free)
5 – Perspective: Beyond Legalization — Dilemmas Physicians Confront Regarding Aid in Dying – New England Journal of Medicine (free)
7 – Pulmonary Function Tests for the Generalist: A Brief Review – Mayo Clinic Proceedings (free)
8 – Catch up on new COPD guidelines – ACP Internist (free)
Original Guideline: 2018 Global Strategy for Prevention, Diagnosis and Management of COPD – Global Initiative for Chronic Obstructive Lung Disease (GOLD) (free PDF)
Pocket Guide: COPD Diagnosis, Management and Prevention (free PDF)
9 – Exercise for cognitive brain health in aging: A systematic review for an evaluation of dose – Neurology Clinical Practice (link to abstract – $ for full-text)
Commentary: How Much Exercise Is Needed to Help Improve Thinking Skills? – American Academy of Neurology, via NewsWise (free) AND Exercise regimen can maintain cognition in older adults, researchers say – UPI (free) AND 1-Hour Exercise, 3 Times a Week Boosts Cognition in Older Adults – MedPage Today (free registration required)
10 – Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: New risk calculator could change the aspirin, statins, and blood pressure medications some people take – STAT (free) AND Statin recommendations may change, especially for African-Americans – CNN (free) AND Millions could have incorrect statin, aspirin and blood pressure prescriptions – Stanford Medicine, via ScienceDaily (free)
Randomized Trial: In Patients Submitted to PCI With High Posttreatment Platelet Reactivity, Treatments Were Compared
6 Jun, 2018 | 21:19h | UTCRandomized Comparisons of Double-Dose Clopidogrel or Adjunctive Cilostazol Versus Standard Dual Antiplatelet in Patients With High Posttreatment Platelet Reactivity: Results of the CREATIVE Trial – Circulation (link to abstract – $ for full-text)
Source: EvidenceAlerts
Mon, June 4 – 10 Stories of The Day!
4 Jun, 2018 | 01:20h | UTC
#ASCO18 – Highlights from the American Society of Clinical Oncology Annual Meeting 2018
1 – #ASCO18 – Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer – New England Journal of Medicine (free)
Commentaries: 2018 ASCO: TAILORx: Most Women With Early-Stage Breast Cancer Can Forgo Chemotherapy When Guided by a Diagnostic Test – The ASCO Post (free) AND Many breast cancer patients can skip chemo, big study finds – STAT (free) AND Many women with early-stage breast cancer can skip chemotherapy: study – Reuters (free) AND For Some Breast Cancer Patients, The Chemo Decision Just Got Easier – NPR (free) AND Breast cancer: Test means fewer women will need chemotherapy – BBC (free) AND Good News for Women With Breast Cancer: Many Don’t Need Chemo – The New York Times (10 articles per month are free)
Commentary: Increase in lifestyle-related cancers over past decade spotlights critical need for prevention – Institute for Health Metrics and Evaluation (free)
3 – #ASCO18 – Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma – New England Journal of Medicine (free)
Editorial: Cytoreductive Nephrectomy — Patient Selection Is Key (free)
Commentaries: 2018 ASCO: Carmena Trial Compares Nephrectomy Plus Adjuvant Sunitinib vs Sunitinib Alone in Metastatic RCC – The ASCO Post (free) AND In Advanced Kidney Cancer, Surgery No Longer Sole Standard of Care – Medscape (free registration required)
4 – #ASCO18 – Pembrolizumab (pembro) versus platinum-based chemotherapy (chemo) as first-line therapy for advanced/metastatic NSCLC with a PD-L1 tumor proportion score (TPS) ≥ 1%: Open-label, phase 3 KEYNOTE-042 study (link to abstract)
Commentaries: 2018 ASCO: KEYNOTE-042 Trial Compares Pembrolizumab With Chemotherapy as First-Line Treatment of NSCLC With PD-L1 Expression of 1% or More – The ASCO Post (free) AND ‘End of an Era’ for Chemo in Non-Small Cell Lung Cancer – Medscape (free registration required)
5 – #ASCO18 – Phase 3 Trial of Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia – New England Journal of Medicine (free)
Commentary: Ibrutinib/Rituximab Improves PFS in Waldenström’s Macroglobulinemia – ASCO Daily News (free)
6 – #ASCO18 – Affordability and Price Increases of New Cancer Drugs in Clinical Guidelines, 2007–2016 – Cancer Spectrum (free) (via @oncology_bg see Tweet)
7 – #ASCO18 – Editorial: Marketing personalized cancer treatments requires careful language – Nature (free)
Related: What Precisely Is Precision Oncology—and Will It Work? – The ASCO Post (free) AND Hope and hype around cancer immunotherapy – CNN (free)
“Therapies tailored to individual tumors must not be oversold”.
8 – #ASCO18 – 2018 ASCO: Low-Dose Maintenance Chemotherapy in Rhabdomyosarcoma – The ASCO Post (free)
9 – #ASCO18 – 2018 ASCO: Blood Test Shows Potential as a Detection Tool for Early-Stage Lung Cancer – The ASCO Post (free)
Commentary: Biotech Firm Grail Takes The First Steps In Its Quest For A Blood Test For Cancer – Forbes (free)
10 – #ASCO18 – Antibiotics greatly reduce effectiveness of cancer treatment – study – The Guardian (free) AND Antibiotics HALVE life expectancy of cancer sufferers, NHS medics reveal in world first at US conference – Daily Maily (free)
Things We Do For No Reason: Neutropenic Diet
1 Jun, 2018 | 04:37h | UTCThings We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (free) (via @guptaarjun90 and @AnilMakam)
Perspective: Sugar, tobacco, and alcohol taxes to achieve the SDGs
1 Jun, 2018 | 04:38h | UTCSugar, tobacco, and alcohol taxes to achieve the SDGs – The Lancet (free registration required)
Commentary: Sugar, tobacco, and alcohol taxes to achieve the Sustainable Development Goals – London School of Hygiene & Tropical Medicine (free)
Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND To improve global health, tax the things that are killing us – Financial Times (free articles, commentaries and reports) AND The Lancet taskforce on NCDs and economics (free series and commentaries)
Position Statement: Guidance for People with Types 1 and 2 Diabetes Who Fast During Ramadan
1 Jun, 2018 | 04:36h | UTC
Cohort Study: Intake of Different Dietary Proteins and Risk of Heart Failure
1 Jun, 2018 | 04:25h | UTCIntake of Different Dietary Proteins and Risk of Heart Failure in Men – Circulation (free)
Commentaries: High protein diet associated with small increased heart failure risk in middle-aged men – AHA Newsroom (free) AND High-Protein Diets May Slightly Increase The Risk Of Heart Disease – Forbes (free)
Perspective: For Patients with Type 2 Diabetes, What’s the Best Target Hemoglobin A1C?
1 Jun, 2018 | 04:36h | UTCFor Patients With Type 2 Diabetes, What’s the Best Target Hemoglobin A1C? – JAMA (free for a limited period)
Related: A1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks – Diabetes Care (free) AND Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)
Disease Outbreak News: Ebola Vaccine Provides Protection and Hope for High-risk Communities in the DRC
1 Jun, 2018 | 04:29h | UTCRelated: Ebola cases drop as more specimens test negative – CIDRAP (free)
Man vs. Machine: Diagnostic Performance of AI for Melanoma Recognition
1 Jun, 2018 | 04:23h | UTCCommentaries: AI surpasses dermatologists at diagnosing skin cancer – ESMO, via eCancer News (free) AND Computer learns to detect skin cancer more accurately than doctors – The Guardian (free) AND A.I. better at diagnosing skin cancer than humans – OnMedica (free)
Report: The Global Health Response to Children & Road Traffic
1 Jun, 2018 | 04:16h | UTCUnfinished Journey: The Global Health Response to Children & Road Traffic – FIA Foundation (free PDF)
News Release: Call for urgent action as ‘fatal disconnect’ in global health policies fails child victims of road traffic (free)
Source: International Health Policies Newsletter
Cohort Study: Lifetime Smoking History and Risk of Lung Cancer
1 Jun, 2018 | 04:14h | UTCLifetime Smoking History and Risk of Lung Cancer: Results From the Framingham Heart Study – Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentaries: Risk of Incident Lung Cancer Drops by 39% Five Years After Smokers Quit – AJMC (free) AND New research finds lung cancer risk drops substantially within five years of quitting – Vanderbilt University Medical Center, via eCancer News (free)
Perspective: How is the World Doing in its Fight Against Vaccine Preventable Diseases?
1 Jun, 2018 | 04:10h | UTCHow is the world doing in its fight against vaccine preventable diseases? – Our World in Data (free)
“Vaccines are amazing: the number of child deaths caused by diseases for which vaccines are available fell by over 2/3 in 25 years. 3.6 million(!) fewer kids under the age of 5 died from these diseases in 2015 than in 1990” (via @DinaPomeranz see Tweet)
Perspective: Why Aren’t We Spending More on Public Health?
1 Jun, 2018 | 04:12h | UTCIt Saves Lives. It Can Save Money. So Why Aren’t We Spending More on Public Health? – The New York Times (10 articles per month are free)
Related: Return on investment of public health interventions: a systematic review – Journal of Epidemiology & Public Health (free)
Source: Global Health NOW Newsletter
Viewpoint: Recalibrating Expectations on Big Data and Predictive Analytics
1 Jun, 2018 | 04:06h | UTCBig Data and Predictive Analytics: Recalibrating Expectations – JAMA (free for a limited period)
Richard Lehman’s journal review, 29 May 2018
1 Jun, 2018 | 04:03h | UTCRichard Lehman’s journal review, 29 May 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Perspective: The Endless Days Of A Young Doctor Battling Ebola
1 Jun, 2018 | 03:57h | UTCThe Endless Days Of A Young Doctor Battling Ebola – NPR (free)
Other Stories on the Ebola Outbreak: Ebola outbreak response shifts to remote DRC hot spots – CIDRAP (free) AND New Ebola Outbreak in Africa Is a Major Test for the WHO – JAMA Forum (free) AND WHO’s Congo Ebola plan assumes 100-300 cases over three months – Reuters (free) AND Ebola outbreak 2018: What’s different this time? – CNN (free) AND More regions to be vaccinated, experimental drugs to be tried in Congo Ebola outbreak – CNN (free)