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ASCO 2018: Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

7 Jun, 2018 | 02:47h | UTC

Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer – New England Journal of Medicine (free)

Editorial: Endocrine Adjuvant Therapy for Localized Breast Cancer (free)

Commentary: Aromatase Inhibitor Plus Ovarian Suppression Yields Benefit in High-Risk Premenopausal Patients With Breast Cancer – The ASCO Post (free)

 


Perspective: Beyond Legalization — Dilemmas Physicians Confront Regarding Aid in Dying

7 Jun, 2018 | 02:47h | UTC

Beyond Legalization — Dilemmas Physicians Confront Regarding Aid in Dying – New England Journal of Medicine (free)

 


Review: Pulmonary Function Tests for the Generalist

7 Jun, 2018 | 02:45h | UTC

Pulmonary Function Tests for the Generalist: A Brief Review – Mayo Clinic Proceedings (free)

 


Research: New Risk Calculator Estimates Millions are Being Overtreated with Statins

7 Jun, 2018 | 02:42h | UTC

Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: New risk calculator could change the aspirin, statins, and blood pressure medications some people take – STAT (free) AND Statin recommendations may change, especially for African-Americans – CNN (free) AND Millions could have incorrect statin, aspirin and blood pressure prescriptions – Stanford Medicine, via ScienceDaily (free) AND Current models overestimate CVD risk of 11.8M US adults – Cardiovascular Business (free)

 


Highlights from the New GOLD COPD Guidelines

7 Jun, 2018 | 02:44h | UTC

Catch up on new COPD guidelines – ACP Internist (free)

Original Guideline: 2018 Global Strategy for Prevention, Diagnosis and Management of COPD – Global Initiative for Chronic Obstructive Lung Disease (GOLD) (free PDF)

Pocket Guide: COPD Diagnosis, Management and Prevention (free PDF)

 


Review: Understanding and Improving the Health of People Who Experience Incarceration

7 Jun, 2018 | 02:46h | UTC

Understanding and Improving the Health of People Who Experience Incarceration: An Overview and Synthesis – Epidemiology Reviews (free)

 


WHO Global Action Plan: More Active People for a Healthier World

7 Jun, 2018 | 02:41h | UTC

More active people for a healthier world: The global action plan on physical activity 2018 – 2030 – World Health Organization (free PDF)

News Release: More active people for a healthier world: The global action plan on physical activity 2018 – 2030 (free resources)

 


ASCO 2018: Preoperative Chemoradiotherapy vs Immediate Surgery for Pancreatic Cancer

7 Jun, 2018 | 02:40h | UTC

PREOPANC-1 Trial Compares Preoperative Chemoradiotherapy vs Immediate Surgery for Pancreatic Cancer – The ASCO Post (free)

Related Video: Pre-operative chemotherapy with radiation may help people with pancreatic cancer live longer – eCancer News (free)

 


Systematic Review: Exercise for Cognitive Brain Health in Aging

7 Jun, 2018 | 02:43h | UTC

Exercise for cognitive brain health in aging: A systematic review for an evaluation of dose – Neurology Clinical Practice (link to abstract – $ for full-text)

Commentary: How Much Exercise Is Needed to Help Improve Thinking Skills? – American Academy of Neurology, via NewsWise (free) AND Exercise regimen can maintain cognition in older adults, researchers say – UPI (free) AND 1-Hour Exercise, 3 Times a Week Boosts Cognition in Older Adults – MedPage Today (free registration required)

 


ASCO 2018: Improved Overall Survival with Adjuvant mFOLFIRINOX in Resected Pancreatic Cancer

7 Jun, 2018 | 02:38h | UTC

Adjuvant mFOLFIRINOX vs Gemcitabine in Resected Pancreatic Cancer – The ASCO Post (free)

Related: Pancreatic Cancer Survival Jumps With Postsurgical Chemo Combo – OncLive (free) AND Study Finds Rare Gain for Tough-To-Treat Pancreatic Cancer – Associated Press (free)

 


Report: WHO Independent High-Level Commission on Noncommunicable Diseases

7 Jun, 2018 | 02:40h | UTC

Time to deliver: report of the WHO Independent High-Level Commission on Noncommunicable Diseases – World Health Organization (free PDF)

News Release: Commission calls for urgent action against chronic diseases (free)

 


Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders

7 Jun, 2018 | 02:37h | UTC

Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders – JAMA Neurology (free for a limited period)

 


Canadian Guideline: Management of Chronic Hepatitis C

7 Jun, 2018 | 02:36h | UTC

The management of chronic hepatitis C: 2018 guideline update from the Canadian Association for the Study of the Liver – Canadian Medical Association Journal (free)

Commentaries: Hepatitis C guideline recommends screening for all people born 1945-1975 – CMAJ, via EurekAlert (free) AND Canadian Group Offers New Guidelines on Hepatitis C Screening, Management – NEJM Physician’s First Watch (free)

Related Guidelines: HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C – American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) (free) AND EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)

 


Review: Optimal Pharmacological Therapy in ST-elevation Myocardial Infarction

7 Jun, 2018 | 02:34h | UTC

Optimal pharmacological therapy in ST-elevation myocardial infarction—a review – Netherlands Heart Journal (free)

Source: Critical Care Reviews Newsletter

 


Richard Lehman’s journal review – 4 June 2018

7 Jun, 2018 | 02:35h | UTC

Richard Lehman’s journal review, 4 June 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Consensus Conference: Cardiac and Vascular Surgery–Associated Acute Kidney Injury

7 Jun, 2018 | 02:36h | UTC

Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group – Journal of the American Heart Association (free)

 


ASCO 2018: Global Burden of Cancer from 1990 to 2016

7 Jun, 2018 | 02:22h | UTC

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study – JAMA Oncology (free)

Commentary: Increase in lifestyle-related cancers over past decade spotlights critical need for prevention – Institute for Health Metrics and Evaluation (free)

 


Implementation Guide: Eliminating Inappropriate Telemetry Monitoring

7 Jun, 2018 | 02:33h | UTC

Eliminating Inappropriate Telemetry Monitoring: An Evidence-Based Implementation Guide – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Continuing to Improve Appropriateness of Continuous Electrocardiographic Monitoring (Telemetry) (free for a limited period)

 


ASCO 2018: Many Women with Early-Stage Breast Cancer Can Forgo Chemotherapy When Guided by a 21-Gene Expression Assay

7 Jun, 2018 | 02:23h | UTC

Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer – New England Journal of Medicine (free)

Commentaries: 2018 ASCO: TAILORx: Most Women With Early-Stage Breast Cancer Can Forgo Chemotherapy When Guided by a Diagnostic Test – The ASCO Post (free) AND Many breast cancer patients can skip chemo, big study finds – STAT (free) AND Many women with early-stage breast cancer can skip chemotherapy: study – Reuters (free) AND For Some Breast Cancer Patients, The Chemo Decision Just Got Easier – NPR (free) AND Breast cancer: Test means fewer women will need chemotherapy – BBC (free) AND Good News for Women With Breast Cancer: Many Don’t Need Chemo – The New York Times (10 articles per month are free)

 


ASCO 2018: Pembrolizumab vs. Chemotherapy as First-line Therapy for Advanced Non-Small Cell Lung Cancer

7 Jun, 2018 | 02:20h | UTC

Pembrolizumab (pembro) versus platinum-based chemotherapy (chemo) as first-line therapy for advanced/metastatic NSCLC with a PD-L1 tumor proportion score (TPS) ≥ 1%: Open-label, phase 3 KEYNOTE-042 study (link to abstract)

Commentaries: 2018 ASCO: KEYNOTE-042 Trial Compares Pembrolizumab With Chemotherapy as First-Line Treatment of NSCLC With PD-L1 Expression of 1% or More – The ASCO Post (free) AND ‘End of an Era’ for Chemo in Non-Small Cell Lung Cancer – Medscape (free registration required)

 


ASCO 2018: Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma

7 Jun, 2018 | 02:21h | UTC

Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma – New England Journal of Medicine (free)

Editorial: Cytoreductive Nephrectomy — Patient Selection Is Key (free)

Commentaries: 2018 ASCO: Carmena Trial Compares Nephrectomy Plus Adjuvant Sunitinib vs Sunitinib Alone in Metastatic RCC – The ASCO Post (free) AND In Advanced Kidney Cancer, Surgery No Longer Sole Standard of Care – Medscape (free registration required)

 


ASCO 2018: Low-Dose Maintenance Chemotherapy in Rhabdomyosarcoma

7 Jun, 2018 | 02:16h | UTC

Low-Dose Maintenance Chemotherapy in Rhabdomyosarcoma – The ASCO Post (free)

 


Research: Affordability and Price Increases of New Cancer Drugs in Clinical Guidelines

7 Jun, 2018 | 02:18h | UTC

Affordability and Price Increases of New Cancer Drugs in Clinical Guidelines, 2007–2016 – Cancer Spectrum (free) (via @oncology_bg see Tweet)

 


ASCO 2018: Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia

7 Jun, 2018 | 02:19h | UTC

Phase 3 Trial of Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia – New England Journal of Medicine (free)

Commentary: Ibrutinib/Rituximab Improves PFS in Waldenström’s Macroglobulinemia – ASCO Daily News (free)

 


Editorial: Marketing Personalized Cancer Treatments Requires Careful Language

7 Jun, 2018 | 02:17h | UTC

Marketing personalized cancer treatments requires careful language – Nature (free)

Related: What Precisely Is Precision Oncology—and Will It Work? – The ASCO Post (free) AND Hope and hype around cancer immunotherapy – CNN (free)

“Therapies tailored to individual tumors must not be oversold”.

 


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