Archives

Liquid-filled Intragastric Balloons by Apollo Endosurgery and ReShape Lifesciences: Letter to Health Care Providers – New Labeling About Potential Risks – FDA (free)

Commentaries: Stomach Balloons Get New Warning Following Deaths – NEJM Physician’s First Watch (free) AND Five More Deaths Linked to Intragastric Balloons for Obesity – Medscape (free registration required)

Tue, June 12 – 10 Stories of The Day!

12 Jun, 2018 | 01:35h | UTC

1 – Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000–15 – The Lancet Global Health (free)

Commentaries: Pneumococcal and Haemophilus influenzae type b disease: moving numbers in the right direction – The Lancet Global Health (free) AND 1.35 million children’s lives saved by HiB and pneumococcal vaccines since 2000 – Johns Hopkins University Bloomberg School of Public Health, via MedicalXpress (free) AND Dramatic reduction in two killer childhood diseases, study finds – The Telegraph (free)

2 – A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: A Trial of Bezafibrate in Primary Biliary Cholangitis – NEJM Resident 360 (free) AND Bezafibrate Normalizes Liver Enzymes in PBC – MedPage Today (free registration required)

“In a randomized trial of patients with primary biliary cholangitis, bezafibrate and ursodeoxycholic acid resulted in a higher rate of complete biochemical response than ursodeoxycholic acid alone” (via @NEJM see Tweet with visual abstract)

3 – Viewpoint: Type 2 Myocardial Infarction—Diagnosis, Prognosis, and Treatment – JAMA (free for a limited period)

4 – Viewpoint: Progress in Prevention and Treatment of Acute Kidney Injury: Moving Beyond Kidney Attack – JAMA (free for a limited period)

5 – Erectile Dysfunction as an Independent Predictor of Future Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis – Circulation (free PDF)

AHA News Release: Erectile dysfunction means increased risk for heart disease, regardless of other risk factors (free)

Commentaries: Men With Erectile Dysfunction Are Twice As Likely to Have Heart Disease, Study Says – TIME (free) AND Erectile Dysfunction Linked To Higher Chances Of Heart Problems In Men – Medical Daily (free)

6 – pH‐neutralizing esophageal irrigations as a novel mitigation strategy for button battery injury – The Laryngoscope (free)

Commentaries: Ingesting honey after swallowing button battery reduces injury and improves outcomes – Children’s Hospital of Philadelphia, via ScienceDaily (free) AND Honey + Sucralfate May Reduce Injury After Accidental Button Battery Ingestion – MPR (free)

7 – Richard Lehman’s journal review, 11 June 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

8 – Hydroxychloroquine: An old drug with new relevance – Cleveland Clinic Journal of Medicine (free)

Source: Hospital Medicine Virtual Journal Club

9 – New European Hypertension Guidelines Not in Harmony With US Guidance – TCTMD (free)

10 – A serious new hurdle for CRISPR: Edited cells might cause cancer, find two studies – STAT (free)

Thu, June 14 – 10 Stories of The Day!

14 Jun, 2018 | 02:26h | UTC

1 – Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: High-tech treatment of open leg wounds no better than using regular dressings – University of Warwick (free) AND Negative-Pressure Therapy No Better for Open Fractures – Medscape (free registration required)

“Negative pressure wound therapy did not improve 12-month disability for patients with severe open fracture of the lower limb compared with standard wound dressing”

2 – Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts – New England Journal of Medicine (free)

Correspondence: Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90 (free)

Commentaries: That Huge Mediterranean Diet Study Was Flawed. But Was It Wrong? – New York Times (free) AND Errors Trigger Retraction Of Study On Mediterranean Diet’s Heart Benefits – NPR (free) AND Expert reaction to retraction and republication of study looking at Mediterranean diet and heart disease – Science Media Centre (free)

3 – Dietary and nutritional approaches for prevention and management of type 2 diabetes – The BMJ (free)

4 – Perspective: The Search for Cancer Treatment Beyond Mutant-Hunting – The New York Times (10 articles per month are free)

5 – Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy – New England Journal of Medicine (free)

Perspective: Trolleyology and the Dengue Vaccine Dilemma – New England Journal of Medicine (free)

Commentaries: Study confirms higher risk of dengue in kids who got Sanofi vaccine – Reuters (free) AND Sanofi’s new dengue challenge: find a diagnostic that will make its vaccine safe to use – STAT (free)

6 – Ebola Situation Report: Ebola Virus Disease in Democratic Republic of Congo – World Health Organization (free)

7 – Thrombocytopenia in the ICU: disseminated intravascular coagulation and thrombotic microangiopathies—what intensivists need to know – Critical Care (free)

8 – Guideline: Cancer of the upper aerodigestive tract: assessment and management in people aged 16 and over – National Institute for Health and Care Excellence (NICE) (free)

9 – Integrative Therapies During and After Breast Cancer Treatment: ASCO Endorsement of the SIO Clinical Practice Guideline – Journal of Clinical Oncology (free)

Commentary: Mozart, meditation and a yoga mat: Oncologists welcome integrative therapies for breast cancer – eCancer News (free)

10 – Association between systolic blood pressure and dementia in the Whitehall II cohort study: role of age, duration, and threshold used to define hypertension – European Heart Journal (free)

Commentaries: Dementia risk increased in 50-year-olds with blood pressure below hypertension threshold – European Society of Cardiology, via EurekAlert (free) AND Blood pressure below treatable threshold linked to heightened dementia risk – OnMedica (free) AND Studies: Higher blood pressure increases risk for dementia – UPI (free) AND High Blood Pressure at Age 50 Tied to Dementia Risk – The New York Times (10 articles per month are free) AND Dementia risk to 50-year-olds with raised blood pressure – study – The Guardian (free)

Fri, June 15 – 10 Stories of The Day!

15 Jun, 2018 | 00:21h | UTC

1 – Report: Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review – Agency for Healthcare Research and Quality (free)

See also: Evidence Summary (free PDF) and Full Report (free PDF)

2 – The WHO essential diagnostic list: a tool for the future – BMJ Global Health Blog (free)

See Original WHO Report: List of Essential In Vitro Diagnostics First edition (2018) – World Health Organization (free report and news release)

3 – Oral Fluconazole in Pregnancy and Risk of Stillbirth and Neonatal Death – JAMA (link to abstract – $ for full-text)

Commentaries: No link found between oral antifungal drug and stillbirth – Karolinska Institutet, via ScienceDaily (free) AND Antifungal Use During Pregnancy and Risk of Stillbirth: What’s the Link? – MPR (free) AND Study Finds No Link Between Fluconazole During Pregnancy and Stillbirth or Neonatal Death – MedicalResearch.com (free) AND Oral Fluconazole for Thrush in Pregnancy Doesn’t Up Stillbirth – Medscape (free registration required)

4 – Controversy: Is there still a place for the Swan-Ganz catheter?

YES (free for a limited period) / NO (free for a limited period) WE ARE NOT SURE (free for a limited period)

5 – Draft Recommendation Statement: Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions – U.S. Preventive Services Task Force (free)

Commentary: USPSTF Again Recommends Screening for Unhealthy Alcohol Use in Adults – NEJM Physician’s First Watch (free)

6 – Flynn effect and its reversal are both environmentally caused – Proceedings of the National Academy of Sciences (link to abstract – $ for full-text)

Commentaries: Researchers find IQ scores dropping since the 1970s – MedicalXpress (free) AND IQ Scores Are Falling in “Worrying” Reversal of 20th Century Intelligence Boom – Science Alert (free) AND IQ Scores Are Falling Due to Environmental Factors, Study Finds – TIME (free)

7 – Diagnosis and management of primary aldosteronism: the Endocrine Society guideline 2016 revisited – European Journal of Endocrinology (free)

8 – Review: Optimal duration of dual antiplatelet therapy for coronary artery disease – Netherlands Heart Journal (free)

9 – Invasive Procedures Associated With the Development of Infective Endocarditis – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Infective endocarditis risk increased after many types of medical procedures – ACP Hospitalist (free) AND Many Invasive Procedures, Including Cardiovascular, Up Risk of Infective Endocarditis – TCTMD (free) AND Invasive procedures—including cardiovascular—boost risk of endocarditis – Cardiovascular Business (free) AND Endocarditis: Any Invasive Procedure Is a Risk – MedPage Today (free registration required)

10 – Effect of Increased Inpatient Attending Physician Supervision on Medical Errors, Patient Safety, and Resident Education: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Effect of increased inpatient attending physician supervision on medical errors, patient safety, and resident education: a randomized clinical trial – PSNet (free) AND Increased attending supervision on rounds didn’t significantly reduce medical errors – ACP Hospitalist (free) AND Additional physician resident supervision doesn’t improve patient safety – Modern Healthcare (free) AND Closer Resident Supervision Does Not Reduce Medical Errors – Medscape (free registration required) AND Is More Supervision of Medical Residents Always Better for Patient Care? – MedicalResearch.com (free)

Wed, June 13 – 10 Stories of The Day!

13 Jun, 2018 | 00:01h | UTC

1 – Screening for Cardiovascular Disease Risk With Electrocardiography: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: The Screening ECG and Cardiac Risks (free) AND Screening for Cardiovascular Disease Risk With Electrocardiography (free)

JAMA Patient Page: Screening for Cardiovascular Disease Risk With ECG (free)

Author Interview: USPSTF Recommendation: Screening for Cardiovascular Disease Risk With Electrocardiography (free audio)

Commentaries: Doctors Told Not To Order Electrocardiograms For Low-Risk Patients – NPR (free) AND USPSTF Finds Insufficient Evidence For Preventative ECG Screening in Asymptomatic, Low-Risk Adults – American College of Cardiology (free) AND Do Not Screen Asymptomatic Adults For CVD With ECGs, Says USPSTF – TCTMD (free)

“The USPSTF recommends against screening with resting or exercise electrocardiography (ECG) to prevent cardiovascular disease (CVD) events in asymptomatic adults at low risk of CVD events”.

2 – Prevalence of Prescription Medications With Depression as a Potential Adverse Effect Among Adults in the United States – JAMA (link to abstract – $ for full-text)

Commentaries: One-Third of US Adults May Unknowingly Use Medications That Can Cause Depression – University of Illinois at Chicago, via EurekAlert (free) AND Many U.S. adults take medicines that can cause depression – Reuters (free) AND Rx With Depression as Potential Adverse Effect Widely Used – Medscape (free registration required)

3 – Clinical Update: Antithrombotic Therapy for Peripheral Artery Disease in 2018 – JAMA (free for a limited period)

4 – Position Paper on Overdiagnosis and Action to be Taken – WONCA (free PDF) (via @RasoiniR)

5 – The American Cancer Society public health statement on eliminating combustible tobacco use in the United States – CA: A Cancer Journal for Clinicians (free)

6 – A sleep prescription for medicine – The Lancet (free registration required)

“Junior doctors working a 34 h shift will make 460% more diagnostic mistakes than when well rested. Matthew Walker asks how can we change the culture of sleep within medicine?” (via @TheLancet see Tweet)

7 – Shaking hands is disgusting – here’s what else you can do – The Conversation (free)

Related: Handshake-free zones to prevent infections? (link to abstract and commentaries)

8 – Antiepileptic drugs in critically ill patients – Critical Care (free)

9 – Work stress and risk of death in men and women with and without cardiometabolic disease: a multicohort study – The Lancet Diabetes & Endocrinology (free)

Commentaries: Stress at work in patients with cardiometabolic disease – The Lancet Diabetes & Endocrinology (free) AND Job strain linked to heightened risk of early death in men with heart disease/diabetes – OnMedica (free) AND Work stress raises risk of premature death in vulnerable men – study – The Guardian (free) AND Job Strain as Bad as Smoking in Men With Diabetes, Heart Disease – Medscape (free registration required)

10 – Association of Viral Suppression With Lower AIDS-Defining and Non–AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Long-term viral suppression may help decrease cancer rates in patients with HIV – ACP Internist (free) AND Long Term HIV Viral Suppression Reduces But Does Not Eliminate Elevated Cancer Risk – MedicalResearch.com (free) AND Viral Suppression of HIV Tied to Less Cancer Risk – NEJM Physician’s First Watch (free)

Building a Great Scientific Abstract: A Quick Checklist

7 Jun, 2018 | 23:35h | UTC

Building a Great Scientific Abstract: A Quick Checklist – by Hilda Bastian, in Absolutely Maybe (free)

Mon, June 11 – 10 Stories of The Day!

11 Jun, 2018 | 00:30h | UTC

1 – The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for Anal Squamous Cell Cancers (Revised 2018) – Diseases of the Colon & Rectum (free)

2 – Association of Long-Term Risk of Respiratory, Allergic, and Infectious Diseases With Removal of Adenoids and Tonsils in Childhood – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)

Commentaries: Tonsillectomy in childhood raises risk of respiratory diseases – OnMedica (free) AND Tonsillectomy, Adenoidectomy in Childhood Tied to Long-Term Health Risks – Physician’s First Watch (free) AND Tonsillectomy Risks May Outweigh Benefits – The New York Times (10 articles per month are free)

3 – Opinion: The flu vaccine is being oversold – it’s not that effective – The Conversation (free)

See Related Cochrane Systematic Reviews: Vaccines for Preventing Influenza and Its Complications (free)

“The infection rate in adults drops from 2% per year to 1%. You could say that’s halved, but it effectively only drops by 1%. So this means that out of every 100 healthy adults vaccinated, 99 get no benefit against laboratory confirmed influenza”.

4 – Outpatient Antibiotic Prescribing for Acute Respiratory Infections During Influenza Seasons – JAMA Network Open (free)

Commentaries: CDC study: Antibiotics still widely overused for respiratory infections – CIDRAP (free) AND Antibiotics Still Widely Prescribed for Viral ARIs – MedPage Today (free)

5 – High-Sensitivity Troponins and Outcomes After Myocardial Infarction – Journal of the American College of Cardiology (free for a limited period)

Commentary: High-Sensitivity Troponins and Outcomes After MI – American College of Cardiology (free) AND Advent of High-Sensitivity Troponin Tests in Sweden Leads to Only Small Uptick in MI Diagnoses – TCTMD (free)

The introduction of high-sensitive troponins was associated with an increased incidence of MI, although with no impact on survival.

6 – Is Posthospital Syndrome a Result of Hospitalization-Induced Allostatic Overload? – Journal of Hospital Medicine (free)

Source: Hospital Medicine Virtual Journal Club

7 – At one-month mark in Ebola outbreak, the focus shifts to remote areas – World Health Organization (free)

8 – Arrhythmia-Induced Cardiomyopathy – Deutsches Ärzteblatt international (free)

9 – Trends in State Suicide Rates — United States, 1999–2016 and Circumstances Contributing to Suicide — 27 States, 2015 – Centers for Disease Control and Prevention (free)

Commentaries: CDC: U.S. Suicide Rates Have Climbed Dramatically – NPR (free) AND CDC: Suicide rates rose 30% across nation since 1999 – UPI (free) AND More Americans Are Dying From Suicide – The Atlantic (free)

10 – Incidence of Diabetes After Cancer Development: A Korean National Cohort Study – JAMA Oncology (free for a limited period)

Commentaries: Diabetes risk increased by 9 cancers – eCancer News (free) AND Cancer Increases Risk of Developing Type 2 Diabetes, Study Finds – AJMC (free) AND Nine Cancers Linked to Diabetes Risk – Medscape (free registration required)

2 – Building a Great Scientific Abstract: A Quick Checklist – by Hilda Bastian, in Absolutely Maybe Blog (free)

3 – Infographic: Global Deaths Attributable to High Systolic Blood Pressure, 1990-2016 – JAMA (free)

4 – Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine (free)

5 – Doctors Scrutinize Overtreatment, As Cancer Death Rates Decline – NPR (free)

6 – Community-level changes in condom use and uptake of HIV pre-exposure prophylaxis by gay and bisexual men in Melbourne and Sydney, Australia: results of repeated behavioural surveillance in 2013–17 – The Lancet HIV (free registration required)

Commentaries: Uptake of PrEP coincides with less condom use – OnMedica (free) AND PrEP uptake on the rise and condom use declines in gay men – News Medical (free) AND A pill that protects people from HIV may also lead to more sex without condoms – Science (free)

Related: How PrEP to Prevent HIV May be Fueling a Rise in Other STDs (link to abstract and commentaries)

7 – Education and myopia: assessing the direction of causality by mendelian randomization – The BMJ (free)

Editorial: Intense schooling linked to myopia (free)

Commentaries: Education and myopia: assessing the direction of causality by mendelian randomization – The BMJ Opinion (free) AND Myopia could be linked to longer periods spent in education – OnMedica (free) AND Highly Educated, Very Nearsighted? – The New York Times (10 articles per month are free)

8 – Job strain and atrial fibrillation – Results from the Swedish Longitudinal Occupational Survey of Health and meta-analysis of three studies – European Journal of Preventive Cardiology (free)

News Release: Stressful jobs are associated with a higher risk of heart rhythm disorders – European Society of Cardiology (free)

9 – Aspirin may be a follow-on option to prevent blood clots, starting five days after hip or knee surgery – NIHR Signal (free)

See Original Article: Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty – New England Journal of Medicine (link to abstract – $ for full-text) AND Quick Take Video Summary: Preventing VTE after Hip or Knee Arthroplasty (free)

10 – Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection) – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Commentary: UV-light cleaning shown to cut superbugs hospital-wide – CIDRAP (free)

Perspective: Doctors Scrutinize Overtreatment in Cancer

7 Jun, 2018 | 23:33h | UTC

Doctors Scrutinize Overtreatment, As Cancer Death Rates Decline – NPR (free)

Cohort Study: Older Age Associated with Worse Outcomes in Major Depressive Disorder

Cohort Study: Exercise Associated with Lower Risk of Mortality in Adult Survivors of Childhood Cancer

Cohort Study: Cesarean Delivery Not Associated with Childhood Obesity

Perspective: Designing Hospitals That Heal as Well as Treat

Expert Analysis: Antiplatelet Therapy Beyond Aspirin in Patients With Stable Ischemic Heart Disease

Retrospective Cohort: Ambulatory Medication Reconciliation and Frequency of Hospitalizations and Emergency Department Visits in Patients With Diabetes

Qualitative Study: Identification and Characterization of Failures in Infectious Agent Transmission Precaution Practices in Hospitals

Summary: PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock

Randomized Trial: Mesh Repair of Small Umbilical Hernias Reduces Recurrence Compared to Sutures

Retrospective Review: Mild to Moderate Isolated Thrombocytopenia Associated with Good Outcomes

Review: ‘Vaginal Seeding’ May do More Harm than Good

Randomized Trial: Antipsychotic Treatment of Very Late-onset Schizophrenia-like Psychosis

Commentary: Burden of Anticoagulation Can Be Reduced in Some Patients with Mechanical Valves

Expert Analysis: The Heart of the Female Athlete

FDA Safety Alert: Liquid-filled Intragastric Balloons

Tue, June 12 – 10 Stories of The Day!

Thu, June 14 – 10 Stories of The Day!

Fri, June 15 – 10 Stories of The Day!

Wed, June 13 – 10 Stories of The Day!

Building a Great Scientific Abstract: A Quick Checklist

Mon, June 11 – 10 Stories of The Day!

Infographic: Global Deaths Attributable to High Systolic Blood Pressure, 1990-2016

Expert Consensus: Management of Adverse Effects of Antiplatelet Therapy for Acute Coronary Syndrome

Fri, June 8 – 10 Stories of The Day!

Perspective: Doctors Scrutinize Overtreatment in Cancer

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