Meta-analysis of randomized trials | Antibiotic therapy vs. appendicectomy for uncomplicated acute appendicitis.

Randomized clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis – BJS Open

Related:

Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis – JAMA Surgery

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

Commentary on Twitter

👼 The reborn of surgery for uncomplicated acute appendicitis ?!

🧐 RCT comparing antibiotic 🤜🤛 appendicectomy: meta analysis of > 3000 patients

💊 No benefit on complications and LOS

🏥 Antibiotics 6X increase in hospital readmission!

🆓 full text https://t.co/VhL9u0Weua pic.twitter.com/SdyK0rKS3f

— Giovanni Marchegiani (@Gio_Marchegiani) August 17, 2022