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Daily Archives: July 21, 2023

2023 AHA/ACC Guideline for chronic coronary disease – B-blockers downgraded in patients without recent MI or low ejection fraction

21 Jul, 2023 | 13:52h | UTC

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

Key Perspectives: 2023 Multisociety Guideline for Managing Chronic Coronary Disease – American College of Cardiology

Top things to know: 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease – American Heart Association

News Releases:

Symptom relief and healthy habits are top goals for treating chronic heart disease – American Heart Association

New ACC, AHA, Multi-Society Guideline Addresses Management of Chronic Coronary Disease – American College of Cardiology

Commentary: New Chronic Heart Disease Guidelines Update Roles of GDMT, Imaging, and Revascularization – TCTMD

 

Commentary on Twitter with key points (thread – click for more)

 


Guideline | Laboratory analysis in the diagnosis and management of diabetes mellitus

21 Jul, 2023 | 13:50h | UTC

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus – Diabetes Care

Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus – Diabetes Care

 


Guideline Synopsis | Diagnosis and management of priapism

21 Jul, 2023 | 13:47h | UTC

Diagnosis and Management of Priapism – JAMA (free for a limited period)

Original Guideline: The Diagnosis and Management of Recurrent Ischemic Priapism, Priapism in Sickle Cell Patients, and Non-Ischemic Priapism: An AUA/SMSNA Guideline – Journal of Urology

 


Cohort Study | ‘Weekend Warrior’ exercise pattern is associated with similar CVD benefits to regular activity

21 Jul, 2023 | 13:46h | UTC

Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease – JAMA (free for a limited period)

News Release: Researchers find ‘weekend warrior’ physical activity provides similar heart-related benefits as more regular exercise – Massachusetts General Hospital

Commentaries:

Good news for ‘weekend warriors’: people who do much of their exercise on a couple of days still get heart benefits – The Conversation

Weekend Warrior Physical Activity and Risk of Cardiovascular Disease – American College of Cardiology

 


Correspondence | Potential “healthy vaccinee bias” in a study of BNT162b2 vaccine against Covid-19

21 Jul, 2023 | 13:43h | UTC

Potential “Healthy Vaccinee Bias” in a Study of BNT162b2 Vaccine against Covid-19 – New England Journal of Medicine

 

Commentary from the author on Twitter (thread – click for more)

 


RCT | MIND diet, a hybrid of Mediterranean and DASH, shows no superiority in preventing cognitive decline

21 Jul, 2023 | 13:38h | UTC

Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

‘MIND diet,’ intended to prevent dementia, doesn’t offer significant brain benefit, trial suggests – Live Science

Revised Mediterranean Diet Shows No Significant Impact on Cognition, MRI Outcomes in Older Persons – Neurology Live

 

Commentary on Twitter

 


RCT | Half-dose Tenecteplase + later PCI if indicated seems to be viable option in older individuals when timely PCI is unavailable

21 Jul, 2023 | 13:36h | UTC

Half-Dose Tenecteplase or Primary Percutaneous Coronary Intervention in Older Patients With ST-Segment–Elevation Myocardial Infarction in STREAM-2: A Randomized, Open-Label Trial – Circulation (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Phase 2 Trial | Maternal GBS6 vaccine shows promise in infant group B strep prevention

21 Jul, 2023 | 13:34h | UTC

Potential for Maternally Administered Vaccine for Infant Group B Streptococcus – New England Journal of Medicine

Commentary: Maternal strep B vaccine slashes risk of infection among infants – CIDRAP

 


Phase 1 Trial | Zilebesiran demonstrates potential as prolonged-action hypertension therapeutic

21 Jul, 2023 | 13:32h | UTC

Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Experimental Shot Given Every Six Months Controlled High Blood Pressure in Early Trial – HealthDay

 


RCT | Molecular screening for bacterial vaginosis does not significantly reduce preterm birth rates

21 Jul, 2023 | 13:31h | UTC

Effectiveness and Costs of Molecular Screening and Treatment for Bacterial Vaginosis to Prevent Preterm Birth: The AuTop Randomized Clinical Trial – JAMA Pediatrics

See also: Visual Abstract

 


Cohort Study | Bipolar disorder associated with a 6-fold higher mortality risk from external causes

21 Jul, 2023 | 13:29h | UTC

Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study – BMJ Mental Health

News Release: Bipolar disorder linked to 6-fold heightened risk of early death from external causes – BMJ Newsroom

 


Systematic Review | Medical treatment of eosinophilic esophagitis

21 Jul, 2023 | 13:27h | UTC

Medical treatment of eosinophilic esophagitis – Cochrane Library

Summary: Medical treatments for eosinophilic esophagitis – Cochrane Library

Related:

RCT | Study finds both one-food and six-food elimination diets are effective initial options for eosinophilic esophagitis

M-A | Efficacy of elimination diets in eosinophilic esophagitis

RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis

A meta-analysis on randomized controlled trials of treating eosinophilic esophagitis with budesonide – Annals of Medicine

A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions – Gastroenterology

British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines on the diagnosis and management of eosinophilic oesophagitis in children and adults – Gut

 


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