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Daily Archives: May 3, 2023

RCT | Best endovascular treatment first strategy yields better outcomes for chronic limb ischemia vs. vein bypass first strategy

3 May, 2023 | 15:39h | UTC

A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial – The Lancet

Commentary: BASIL-2 Supports Endo-First Strategy for CLTI With Infrapopliteal Disease – TCTMD

 


M-A | Efficacy of osteoporosis interventions on fracture prevention in postmenopausal women

3 May, 2023 | 15:37h | UTC

Fracture risk reduction and safety by osteoporosis treatment compared with placebo or active comparator in postmenopausal women: systematic review, network meta-analysis, and meta-regression analysis of randomised clinical trials – The BMJ

 


Cluster RCT | Eat, sleep, console approach vs. usual care for neonatal opioid withdrawal

3 May, 2023 | 15:35h | UTC

Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: “Eat, Sleep, Console” reduces hospital stay and need for medication among opioid-exposed infants – NIH News Releases

 

Commentary on Twitter

 


M-A | Direct oral anticoagulants versus warfarin across the spectrum of kidney function in patients with AF

3 May, 2023 | 15:32h | UTC

Direct Oral Anticoagulants Versus Warfarin Across the Spectrum of Kidney Function: Patient-Level Network Meta-Analyses From COMBINE AF – Circulation (free for a limited period)

 

Commentary on Twitter

 


Big little lies: a compendium and simulation of p-hacking strategies

3 May, 2023 | 15:30h | UTC

Big little lies: a compendium and simulation of p-hacking strategies – Royal Society Open Science

 


Differential diagnosis, prevention, and treatment of mpox (Monkeypox): a review for dermatologists

3 May, 2023 | 15:27h | UTC

Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

Related: Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

 


SR | Fecal microbiota transplantation effective in recurrent C. difficile treatment

3 May, 2023 | 15:29h | UTC

Fecal microbiota transplantation for the treatment of recurrent Clostridioides difficile (Clostridium difficile) – Cochrane Library

Summary: Stool transplantation for treatment of repeated Clostridioides difficile infection – Cochrane Library

Commentaries:

Cochrane study finds stool transplants more effective than antibiotics for treating recurring, life-threatening gut infections – Cochrane Library

Expert reaction to two Cochrane reviews looking at stool transplants for recurrent Clostridium difficile infection, and for inflammatory bowel disease – Science Media Centre

Fecal microbiota transplant: Effective solution for recurrent C. difficile infections – News Medical

Related:

RCT | Fecal microbiota transplantation better than standard of care for first or second Clostridioides difficile infection.

Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection

 

Commentary on Twitter

 


Supportive care management recommendations for mucocutaneous manifestations of monkeypox infection

3 May, 2023 | 15:26h | UTC

Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

Related: Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

 


Scientific Statement | Iron deficiency in heart failure

3 May, 2023 | 15:25h | UTC

Iron Deficiency in Heart Failure: A Scientific Statement from the Heart Failure Society of America – Journal of Cardiac Failure

 


Clinical practice guidelines on hemochromatosis

3 May, 2023 | 15:23h | UTC

Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver – Hepatology International

 


Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis

3 May, 2023 | 15:22h | UTC

Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis – Gut

 


Review | Calciphylaxis and kidney disease

3 May, 2023 | 15:20h | UTC

Calciphylaxis and Kidney Disease: A Review – American Journal of Kidney Diseases

 


ATS Research Statement | Causes, consequences, and treatments of sleep and circadian disruption in the ICU

3 May, 2023 | 15:18h | UTC

Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement – American Journal of Respiratory and Critical Care Medicine

 

Commentary on Twitter

 


RCT | Levonorgestrel IUS vs. hysteroscopic niche resection for postmenstrual spotting in cesarean scar

3 May, 2023 | 15:15h | UTC

Comparing levonorgestrel intrauterine system with hysteroscopic niche resection in women with postmenstrual spotting related to a niche in the uterine cesarean scar: a randomized, open-label, controlled trial – American Journal of Obstetrics & Gynecology

 


Review | Leveraging electronic health records to streamline the conduct of cardiovascular clinical trials

3 May, 2023 | 15:10h | UTC

Leveraging electronic health records to streamline the conduct of cardiovascular clinical trials – European Heart Journal (free for a limited period)

 


Perspective | Ableism in the intensive care unit

3 May, 2023 | 15:14h | UTC

Ableism in the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


RCT | Evaluating subcutaneous rituximab for the first-line treatment of low–tumor burden follicular lymphoma

3 May, 2023 | 15:07h | UTC

Randomized Phase III Trial Evaluating Subcutaneous Rituximab for the First-Line Treatment of Low–Tumor Burden Follicular Lymphoma: Results of a LYSA Study – Journal of Clinical Oncology (link to abstract – $ for full-text)

 


ISHLT Guidelines for the care of heart transplant recipients

3 May, 2023 | 15:09h | UTC

The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients – The Journal of Heart and Lung Transplantation

 


M-A | Long-term major adverse cardiovascular events following myocardial injury after non-cardiac surgery

3 May, 2023 | 15:05h | UTC

Long-term major adverse cardiovascular events following myocardial injury after non-cardiac surgery: meta-analysis – BJS Open

 

Commentary on Twitter

 


RCT | Efficacy and safety of tralokinumab in adolescents with moderate to severe atopic dermatitis

3 May, 2023 | 15:04h | UTC

Efficacy and Safety of Tralokinumab in Adolescents With Moderate to Severe Atopic Dermatitis: The Phase 3 ECZTRA 6 Randomized Clinical Trial – JAMA Dermatology

Commentary: Tralokinumab Efficacious, Well-Tolerated for Adolescents with Atopic Dermatitis – HCP Live

 

Commentary on Twitter

 


A comparison between early presentation of dementia with Lewy Bodies, Alzheimer’s disease and Parkinson’s disease

3 May, 2023 | 15:02h | UTC

A comparison between early presentation of dementia with Lewy Bodies, Alzheimer’s disease and Parkinson’s disease: evidence from routine primary care and UK Biobank data – Annals of Neurology

 


RCT | High vs. low target mean arterial pressure in patients with cirrhosis and septic shock

3 May, 2023 | 15:01h | UTC

A randomized-controlled trial (TARGET-C) of high vs. low target mean arterial pressure in patients with cirrhosis and septic shock – Journal of Hepatology

 


ACP Guidance | Beyond the Discharge: Principles of effective care transitions between settings

3 May, 2023 | 14:57h | UTC

ACP makes recommendations to improve transitions between health care settings – American College of Physicians

News Release: ACP Makes Recommendations to Improve Transitions Between Health Care Settings

 


Brief Review | Personalized noninvasive respiratory support for acute hypoxemic respiratory failure

3 May, 2023 | 15:00h | UTC

Personalized noninvasive respiratory support for acute hypoxemic respiratory failure – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Cohort Study | Long-term health consequences after ovarian removal at benign hysterectomy

3 May, 2023 | 14:58h | UTC

Long-Term Health Consequences After Ovarian Removal at Benign Hysterectomy: A Nationwide Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Risks of removing ovaries at benign hysterectomy may outweigh the benefits for women at low risk for ovarian cancer – American College of Physicians

 


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