Daily Archives: April 25, 2023
AGA Practical Guidance | Diagnosis and management of extraesophageal gastroesophageal reflux disease
25 Apr, 2023 | 14:50h | UTCCommentary: Guidance offered on management of extraesophageal GERD – ACP Gastroenterology
Commentary on Twitter (thread – click for more)
Looking for guidance on management of extraesophageal reflux?? Check out our Best Practice Advice in the latest AGA Clinical Practice Update on Management of EER @AGA_CGH. @AmerGastroAssn
Read the article➡️:https://t.co/S6WYsQUoTj pic.twitter.com/UqjDR2JXP8
— Joan Chen, MD MS (@joanwchen) April 19, 2023
ASCO Guideline Update | Venous thromboembolism prophylaxis and treatment in patients with cancer
25 Apr, 2023 | 14:49h | UTC
RCT | Effectiveness of an over-the-counter self-fitting hearing aid compared with an audiologist-fitted hearing aid
25 Apr, 2023 | 14:47h | UTCAuthor Interview: Effectiveness of Self-fitting vs Audiologist-Fitted Hearing Aids – JAMA
Commentaries:
Self-Fitting, Over-the-Counter Hearing Aids Beneficial – HealthDay
How Do Over-the-Counter Hearing Aids Compare with Those Fitted by Audiologists? – NEJM Journal Watch (free for a limited period)
Commentary on Twitter
Findings suggest that a self-fitting OTC hearing aid may be an effective intervention option for individuals with mild to moderate #hearingloss and produce self-perceived and clinical outcomes similar to those of an audiologist-fitted #hearingaid. https://t.co/Zbc8URj2uA
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) April 13, 2023
RCT | Cerebral oximetry monitoring fails to reduce death or severe brain injury in extremely preterm infants
25 Apr, 2023 | 14:45h | UTCCerebral Oximetry Monitoring in Extremely Preterm Infants – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In extremely preterm infants, the use of cerebral oximetry monitoring to guide treatment for the first 72 hours after birth did not reduce the risk of death or severe brain injury at 36 weeks’ postmenstrual age. Full study: https://t.co/JX7Ra3OpjM pic.twitter.com/VACbUUAq3i
— NEJM (@NEJM) April 19, 2023
Cohort Study | Impact of work schedules of senior resident physicians on patient and resident physician safety
25 Apr, 2023 | 14:43h | UTCNews Release: National Study of Resident Physicians Suggests Need for Federal Work Hour Guideline Changes – Brigham and Women’s Hospital
Commentaries:
Resident Doctors’ Long Work Shifts Could Bring Peril to Patients – HealthDay
SR | Cranberries can prevent recurrent urinary tract infections in selected patients
25 Apr, 2023 | 14:41h | UTCCranberries for preventing urinary tract infections – Cochrane Library
Summary: Cranberries for preventing urinary tract infections – Cochrane Library
Commentaries:
Cranberry juice can prevent recurrent UTIs, but only for some people – The Conversation
Review confirms that cranberry products help prevent urinary tract infections – News Medical
Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary
25 Apr, 2023 | 14:42h | UTCSummary: 2023 GOLD Guidelines for Chronic Obstructive Pulmonary Disease – NEJM Journal Watch (free for a limited period)
Original Guidance: 2023 GOLD REPORT: global strategy for prevention, diagnosis and management of COPD: 2023 Report – Global Initiative for Chronic Obstructive Lung Disease
M-A | Surgical versus non-surgical treatment for sciatica
25 Apr, 2023 | 14:39h | UTCEditorial: Early surgery for sciatica – The BMJ
News Release: Surgery for sciatica reduces leg pain and disability, but benefits are short-lived – University of Oxford
Commentary on Twitter
Very low to low certainty evidence suggests that discectomy was superior to non-surgical treatment or epidural steroid injections in reducing leg pain and disability in people with sciatica with a surgical indication, but the benefits reduced over timehttps://t.co/kHL2HBNscF
— The BMJ (@bmj_latest) April 19, 2023
Antiplatelet strategies following PCI: a review of trials informing current and future therapies
25 Apr, 2023 | 14:38h | UTC
Review | Risk stratification of low-risk prostate cancer: individualizing care in the era of active surveillance
25 Apr, 2023 | 14:35h | UTCRisk Stratification of Low-Risk Prostate Cancer: Individualizing Care in the Era of Active Surveillance – Journal of Urology (free PDF for a limited period)
Related:
Low-Value Prostate-Specific Antigen Screening in Older Males – JAMA Network Open
RCT | Patient-reported outcomes 12 years after different treatments for localized prostate cancer
RCT | Localized prostate cancer treatment options have similar 15-year survival outcomes
Perspective | Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms
25 Apr, 2023 | 14:37h | UTC
Commentary on Twitter
Liver #Tx in severe acute on chronic failure
➡️ #ICU care crucial in ACLF-3
➡️ improve referrals to LT centers & pre-LT workup
➡️ to decide to put pt on waitlist consider donor shortage/collective utility of LT
➡️ identifying transplantability window
?️ https://t.co/VZxDyZ1k74 pic.twitter.com/6YOcd5rzMu— Intensive Care Medicine (@yourICM) April 19, 2023
Cardiovascular disease in testicular cancer survivors: Identification of risk factors and impact on quality of life
25 Apr, 2023 | 14:34h | UTC
Burden of typhoid and paratyphoid fever in India
25 Apr, 2023 | 14:32h | UTCBurden of Typhoid and Paratyphoid Fever in India – New England Journal of Medicine
Commentary on Twitter
From 2017 through 2020 in India, weekly surveillance for blood-confirmed typhoid and paratyphoid among children showed an incidence of 576 to 1173 cases of typhoid fever per 100,000 child-years in urban sites. Full NSSEFI study: https://t.co/BbweY5hVcQ#InfectiousDisease pic.twitter.com/S2D3bM29f5
— NEJM (@NEJM) April 19, 2023
Pro-Con Debate | Peripheral nerve blockade should be provided routinely in extremity trauma
25 Apr, 2023 | 14:31h | UTCPro-Con Debate: Peripheral Nerve Blockade Should Be Provided Routinely in Extremity Trauma, Including in Patients At Risk for Acute Compartment Syndrome – Anesthesia & Analgesia (free for a limited period)
Cohort Study | Risk of cancer after diagnosis of cardiovascular disease
25 Apr, 2023 | 14:29h | UTCRisk of Cancer After Diagnosis of Cardiovascular Disease – CardioOncology
Commentary: New details on the link between CVD and cancer, from a study of 27M patients – Cardiovascular Business
Sudden unexpected infant deaths in the US: 2015–2020
25 Apr, 2023 | 14:27h | UTCSudden Unexpected Infant Deaths: 2015–2020 – Pediatrics
Commentary:
Increasing Disparities in Sudden Unexpected Infant Deaths Reflect Societal Failures – Pediatrics
2020 spike in SIDS likely due to diagnostic shifting, not COVID-19 – Contemporary Pediatrics
Characteristics of fatal poisonings among infants and young children in the US
25 Apr, 2023 | 14:28h | UTC
Clinical Trial Update | Nivolumab plus Relatlimab for advanced melanoma fail to reach OS threshold despite PFS improvement
25 Apr, 2023 | 14:25h | UTCOverall Survival and Response with Nivolumab and Relatlimab in Advanced Melanoma – NEJM Evidence
Original Study: Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma – New England Journal of Medicine
Commentary on Twitter
Original Article: “Overall Survival and Response with Nivolumab and Relatlimab in Advanced Melanoma,” by Georgina V. Long, MD, PhD, et al. https://t.co/g5N1AYQV1I#OncoAlert #Melanoma
— NEJM Evidence (@NEJMEvidence) April 19, 2023
Cohort Study | Osmotic demyelination syndrome in patients hospitalized with hyponatremia
25 Apr, 2023 | 14:26h | UTCOsmotic Demyelination Syndrome in Patients Hospitalized with Hyponatremia – NEJM Evidence
RCT | Intraperitoneal carboplatin achieves modest PFS gains in advanced ovarian cancer
25 Apr, 2023 | 14:24h | UTCIntraperitoneal Carboplatin for Ovarian Cancer — A Phase 2/3 Trial – NEJM Evidence
Commentary on Twitter
“In the first-line treatment of advanced epithelial ovarian cancer, intraperitoneal carboplatin resulted in a modest prolongation of PFS [progression-free survival] when given with dose-dense weekly paclitaxel regardless of residual tumor size….”#MedTwitter #ClinicalTrials
— NEJM Evidence (@NEJMEvidence) April 23, 2023
SR | Angiogenesis inhibitors for the treatment of epithelial ovarian cancer
25 Apr, 2023 | 14:22h | UTCAngiogenesis inhibitors for the treatment of epithelial ovarian cancer – Cochrane Library
Brief Review | Diagnosis and management of adrenal insufficiency
25 Apr, 2023 | 14:18h | UTCDiagnosis and management of adrenal insufficiency – Clinical Medicine Journal
Brief Review | Diagnosis and management of neuroendocrine tumors
25 Apr, 2023 | 14:16h | UTCDiagnosis and management of neuroendocrine tumours – Clinical Medicine Journal
Brief Review | Management of pituitary incidentalomas
25 Apr, 2023 | 14:14h | UTCManagement of pituitary incidentalomas – Clinical Medicine Journal
Brief Review | Investigation and assessment of adrenal incidentalomas
25 Apr, 2023 | 14:13h | UTCInvestigation and assessment of adrenal incidentalomas – Clinical Medicine Journal