Daily Archives: December 2, 2022
Consensus Recommendations | Antiretroviral drugs for treatment and prevention of HIV infection in adults.
2 Dec, 2022 | 14:45h | UTCAntiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults2022 Recommendations of the International Antiviral Society–USA Panel – JAMA (free for a limited period)
Invited Commentary: Ending the HIV Epidemic: We Have the Tools, Do We Have the Will? – JAMA (free for a limited period)
Author Interview: Advances in Treatment and Prevention of HIV – JAMA
WHO issues consolidated guide to running effective telemedicine services.
2 Dec, 2022 | 14:43h | UTCNews Release: WHO issues consolidated guide to running effective telemedicine services – World Health Organization
Original Report: Consolidated telemedicine implementation guide – World Health Organization
RCT | Lecanemab slows cognitive decline in early Alzheimer’s disease but raises safety concerns.
2 Dec, 2022 | 14:40h | UTCLecanemab in Early Alzheimer’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Heralded Alzheimer’s drug works — but safety concerns loom – Nature
Lecanemab and Alzheimer’s: More Data – Science
Alzheimer’s Drug is Hailed Amid Safety Concerns – Health Policy Watch
Related: Second death linked to potential antibody treatment for Alzheimer’s disease – Science
Commentary on Twitter
In a phase 3 trial, participants with early Alzheimer’s disease who received the monoclonal antibody lecanemab had less decline on measures of cognitive function at 18 months than those who received placebo. https://t.co/NjEloWVk1V pic.twitter.com/n33yjV9117
— NEJM (@NEJM) November 30, 2022
Cohort Study | Buprenorphine may be a safer option than Methadone for opioid use disorder in pregnancy.
2 Dec, 2022 | 14:42h | UTCBuprenorphine versus Methadone for Opioid Use Disorder in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)
RCT | Effects of internet-delivered cognitive behavioral therapy on use of child sexual abuse material.
2 Dec, 2022 | 14:38h | UTCNews Release: Reduced use of child sexual abuse material after online CBT – Karolinska Institutet
Commentary on Twitter (thread – click for more)
NOVEL STUDY:
Tailor-made, online psychological intervention may reduce use of child sexual abuse material (CSAM, formerly "child pornography") among adults recruited on #Darknet
Randomized controlled trial published with open access:https://t.co/SGnti4rtso
Thread?— Niklas Långström (@NiklasLangstrom) December 1, 2022
Case-control study | Effectiveness of COVID-19 vaccines against infection and mortality in children in Argentina.
2 Dec, 2022 | 14:36h | UTC
RCT | Single-dose Acoziborole is effective and safe for patients with sleeping sickness.
2 Dec, 2022 | 14:35h | UTCNews Release: New single-dose treatment for sleeping sickness could help eliminate transmission of the disease by 2030 – The Lancet
Commentary: Single dose of acoziborole 95% effective in treating sleeping sickness – CIDRAP
Cross-sectional study | Overweight women may be at increased risk of long Covid.
2 Dec, 2022 | 14:33h | UTCCommentaries:
Overweight women may be at highest risk of long COVID – new research – The Conversation
Recommendations on controversial issues in diagnosis and management of hyponatremia.
2 Dec, 2022 | 14:28h | UTC
Perspective | Push to use antibiotics to prevent sexually transmitted infections raises concerns.
2 Dec, 2022 | 14:27h | UTCPush to use antibiotics to prevent sexually transmitted infections raises concerns – Nature
M-A | Risk of hypovolemia associated with sodium–glucose cotransporter-2 inhibitors treatment.
2 Dec, 2022 | 14:31h | UTC
Perspective | Clinical trials and pregnancy.
2 Dec, 2022 | 14:25h | UTCClinical trials and pregnancy – Communications Medicine
Related:
M-A | Association between the FRAIL Scale and postoperative complications in older surgical patients.
2 Dec, 2022 | 14:21h | UTC
Commentary on Twitter
Study showing FRAIL scale association with 30-d & 6 mo mortality, postop complications, & delirium.Odds ratios are nice but actual% may be more helpful.If OR is 3 but % complications is 0.5%, it’s not that meaningful.Need both for informed decision-makinghttps://t.co/V5qfEDHslQ
— Steven Cohn, MD (@preopconsult) November 30, 2022
Opinion | Regression towards the mean—a plea for civility in peer review.
2 Dec, 2022 | 14:22h | UTCOpinion: Regression towards the mean—a plea for civility in peer review – The BMJ
RCT | Rivaroxaban prophylaxis in noncirrhotic portal vein thrombosis.
2 Dec, 2022 | 14:24h | UTCRivaroxaban Prophylaxis in Noncirrhotic Portal Vein Thrombosis – NEJM Evidence
Commentary on Twitter
This #RCT examined the use of rivaroxaban to reduce risk of venous thromboembolism (VTE) in pts with non-cirrhotic chronic portal vein thrombosis (PVT). Daily rivaroxaban reduced incidence of VTE and did not increase major bleeding events. https://t.co/CbenUb8ZWz#LiverTwitter pic.twitter.com/bgN1QS171j
— NEJM Evidence (@NEJMEvidence) November 22, 2022
Epidemiology of heart failure in young adults: a French nationwide cohort study.
2 Dec, 2022 | 14:19h | UTC
Predatory conferences: a systematic scoping review.
2 Dec, 2022 | 14:17h | UTCPredatory conferences: a systematic scoping review – BMJ Open
Cross-sectional study | Students attending online courses were at increased risk of psychological distress during the COVID-19 pandemic.
2 Dec, 2022 | 14:16h | UTC
Commentary on Twitter
?More data that hybrid >> online only ? @JAMANetworkOpen: https://t.co/5vMrrmeGIw
Cross-sectional study of 59k college students (61% online only, 35% mixed online/in-person) found online only ⬆️ psychological distress (b = 0.76 [99% CI, 0.64-0.88]; P < .001). @dsouzl @roecsg
— Erin Gillespie, MD (@ErinGillespieMD) November 30, 2022
Review | Contemporary management of concomitant cardiac arrest and cardiogenic shock complicating myocardial infarction.
2 Dec, 2022 | 14:11h | UTC
Cohort Study | Tobacco smoking and risks of more than 470 diseases in China.
2 Dec, 2022 | 14:14h | UTCCommentary: Smoking increases the risks of 56 diseases in Chinese adults – Oxford University
Review | Acute and chronic alcoholic pancreatitis, including paraduodenal pancreatitis.
2 Dec, 2022 | 14:08h | UTC