Daily Archives: November 9, 2022
Guideline | Intravenous maintenance fluid therapy in acute and critically ill children.
9 Nov, 2022 | 12:32h | UTC
Commentary on Twitter
The @ESPNIC_Society guidelines for IV maintenance fluid therapy in acute & critically ill children, SR/MA:
➡️indications for use
💧isotonic fluids
💧balanced solutions
💧composition: Ca, Mg, K, glucose, micronutrients
💧optimal amount#PedsICU #FOAMcc
🗞️https://t.co/ZZwHX1IaUh pic.twitter.com/KGr4e2dFg4— Intensive Care Medicine (@yourICM) October 26, 2022
AHA Scientific Statement | Arrhythmias in repaired Tetralogy of Fallot.
9 Nov, 2022 | 12:33h | UTCSummary: Arrhythmias in Repaired Tetralogy of Fallot – American Heart Association
Top Things to Know: Arrhythmias in Repaired Tetralogy of Fallot – American Heart Association
Commentary: Challenges in Managing Arrhythmias in Adult Tetralogy of Fallot – American Heart Association
RCT | Using an algorithm to stratify the risk of patients with acute heart failure may improve outcomes.
9 Nov, 2022 | 12:30h | UTCTrial of an Intervention to Improve Acute Heart Failure Outcomes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: New Tool Assesses Risk in Acute HF Then Suggests Next Steps, Cutting Later Events – TCTMD
Commentary on Twitter
The use of a validated tool for risk assessment, combined with rapid follow-up, led to a lower risk of death or hospitalization for cardiovascular causes at 30 days among patients with acute heart failure. #AHA22 https://t.co/0cbvcHl3US pic.twitter.com/kpWbRGpOJX
— NEJM (@NEJM) November 5, 2022
RCT | In infants undergoing heart surgery, prophylactic methylprednisolone did not significantly improve outcomes.
9 Nov, 2022 | 12:31h | UTCMethylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Steroids during surgery may not be helpful for infants having heart bypass – American Heart Association
Commentary on Twitter
In this randomized, controlled trial involving infants undergoing surgery with cardiopulmonary bypass, prophylactic use of methylprednisolone did not significantly reduce the likelihood of a worse outcome. #AHA22 https://t.co/jaza6JCAuk pic.twitter.com/lLrxci7SaE
— NEJM (@NEJM) November 6, 2022
Study Commentary | Radial artery beats both right internal thoracic artery and vein grafting at 15 years.
9 Nov, 2022 | 12:28h | UTC(Not published yet, presented at the American Heart Association Scientific Sessions, November 6, 2022)
RAPCO: Radial Artery Beats Both RITA and Vein Grafting at 15 Years – TCTMD
See also:
Related:
Meta-Analysis: Radial-Artery vs Saphenous-Vein Grafts in CABG
M-A | DOACs increase the risk of arterial thrombosis vs. Vitamin-K antagonists in antiphospholipid syndrome.
9 Nov, 2022 | 12:28h | UTCDirect Oral Anticoagulants vs Vitamin-K Antagonists in Thrombotic Antiphospholipid Syndrome: Meta-analysis of Randomized Controlled Trials – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Guidelines | Managing functional dyspepsia overlapping with other gastrointestinal symptoms.
9 Nov, 2022 | 12:26h | UTC
RCT | Effect of text messaging parents of school-aged children on outdoor time to control myopia.
9 Nov, 2022 | 12:26h | UTC
Commentary on Twitter
Using text message reminders to parents offer improved control of #myopia in schoolchildren and should be considered for use with large populations and over large geographic areas. https://t.co/6Dpue8j3Om #Research pic.twitter.com/IMpyGZUQyV
— JAMA Pediatrics (@JAMAPediatrics) September 26, 2022
Consensus Paper | Health emergency and disaster risk management workforce development strategies.
9 Nov, 2022 | 12:25h | UTC
Single-arm P2 study | Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas.
9 Nov, 2022 | 12:24h | UTCHypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open-label, single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)
Complexities of care: common components of models of care in geriatrics.
9 Nov, 2022 | 12:22h | UTC
Cohort Study | Population-based estimates of 1-year mortality after major surgery among community-living older adults.
9 Nov, 2022 | 12:23h | UTCPopulation-Based Estimates of 1-Year Mortality After Major Surgery Among Community-Living Older US Adults – JAMA Surgery (link to abstract – $ for full-text)
Commentaries:
One in Seven Older Adults Die Within a Year After Surgery – Medscape (free registration required)
Surgery Holds Danger for Seniors. Who’s Most at Risk? – HealthDay
Commentary on Twitter
In a nationally representative sample of community-living Americans aged ≥65 years, nearly 1 out of every 7 persons died in the year after major surgery, including more than 1 of 4 who were frail and nearly 1 of 3 who had probable #dementia. https://t.co/nf8W4oLOLd @NHATS_NSOC
— JAMA Surgery (@JAMASurgery) October 19, 2022
Phase 2 RCT | Concurrent Bevacizumab and reirradiation vs. Bevacizumab alone as treatment for recurrent glioblastoma.
9 Nov, 2022 | 12:21h | UTCNRG Oncology/RTOG1205: A Randomized Phase II Trial of Concurrent Bevacizumab and Reirradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: Bevacizumab Plus Reirradiation Improves PFS in Glioblastoma Multiforme – OncLive
M-A | Comparative efficacy of antiplatelet or anticoagulant therapy in patients with chronic coronary syndromes after PCI.
9 Nov, 2022 | 12:20h | UTC
Scoop thrombectomy | Single-center results of a declotting technique for thrombosed autologous arteriovenous fistula.
9 Nov, 2022 | 12:20h | UTC
M-A | Strategies for post–cardiac surgery acute kidney injury prevention.
9 Nov, 2022 | 12:19h | UTC
Cohort Study | Association of hormone therapy with depression during menopause.
9 Nov, 2022 | 12:17h | UTCCommentaries:
Expert reaction to study looking at HRT and depression during the menopause – Science Media Centre
Commentary on Twitter
Systemic hormone therapy (HT) before and during menopause is associated with higher risk of depression, especially in the years immediately after initiation; locally administered HT is associated with lower risk of depression for women ≥54 years. https://t.co/8k44K8SVtp
— JAMA Network Open (@JAMANetworkOpen) November 1, 2022
RCT | Chronic remote ischemic conditioning is not beneficial for patients with symptomatic intracranial atherosclerotic stenosis.
9 Nov, 2022 | 12:18h | UTCChronic remote ischaemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis (the RICA trial): a multicentre, randomised, double-blind sham-controlled trial in China – The Lancet Neurology (link to abstract – $ for full-text)
Defining the optimum strategy for identifying adults and children with celiac disease: systematic review and economic modeling.
9 Nov, 2022 | 12:16h | UTC
Cohort Study | Associations between childhood trauma and childhood psychiatric disorders in Brazil.
9 Nov, 2022 | 12:15h | UTCCommentary: Birth cohort study reveals the mental health burden of trauma in childhood – University of Bath
Review | Direct oral anticoagulants for the prevention and acute treatment of cancer-associated thrombosis.
9 Nov, 2022 | 12:13h | UTC
M-A | Point-of-care ultrasound evaluation for patients with acute onset dyspnea.
9 Nov, 2022 | 12:14h | UTC
RCT | Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma.
9 Nov, 2022 | 12:12h | UTCComparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)
RCT | Efficacy of 9 months of delamanid, linezolid, levofloxacin, and pyrazinamide for treatment of fluoroquinolone-sensitive MDR-TB.
9 Nov, 2022 | 12:11h | UTC9 months of delamanid, linezolid, levofloxacin, and pyrazinamide versus conventional therapy for treatment of fluoroquinolone-sensitive multidrug-resistant tuberculosis (MDR-END): a multicentre, randomised, open-label phase 2/3 non-inferiority trial in South Korea – The Lancet (link to abstract – $ for full-text)
RCT | Moxidectin and albendazole vs. ivermectin and albendazole in adolescents infected with Trichuris trichiura.
9 Nov, 2022 | 12:10h | UTCInvited Commentary: Alternative treatment strategies for trichuriasis – The Lancet Infectious Diseases


