Daily Archives: October 19, 2022 | LinksMedicus Free Medical News & Perspectives

Crossover RCT | Spinal cord burst stimulation does not improve disability in chronic radicular pain after lumbar spine surgery.

19 Oct, 2022 | 14:29h | UTC

Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary on Twitter

Among patients with chronic radicular pain after lumbar spine surgery, spinal cord burst stimulation, compared with placebo stimulation, resulted in no significant difference in back pain–related disability. https://t.co/XGiRRB4Njm #Research

— JAMA (@JAMA_current) October 18, 2022

Pooled analysis of cohort studies | Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters.

19 Oct, 2022 | 14:28h | UTC

Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales – The Lancet

Commentaries:

Prioritisation of COVID-19 boosters in the omicron era – The Lancet

COVID booster halved severe illness, but some groups still at higher risk – CIDRAP

RCT | Efficacy of BCG vaccination in reducing the incidence and severity of COVID-19 in a high-risk population.

19 Oct, 2022 | 14:26h | UTC

Efficacy of Bacillus Calmette–Guérin (BCG) Vaccination in Reducing the Incidence and Severity of COVID-19 in High-Risk Population (BRIC): a Phase III, Multi-centre, Quadruple-Blind Randomised Control Trial – Infectious Diseases and Therapy

Case-control study | Odds of hospitalization for COVID-19 after 3 vs. 2 doses of mRNA vaccine by time since booster dose.

19 Oct, 2022 | 14:27h | UTC

Odds of Hospitalization for COVID-19 After 3 vs 2 Doses of mRNA COVID-19 Vaccine by Time Since Booster Dose – JAMA

News Release: Study indicates COVID-19 boosters among vaccinated individuals significantly reduce hospitalization rates – Providence Health & Services

Consensus Paper | Surgical management of giant pituitary neuroendocrine tumors.

19 Oct, 2022 | 14:25h | UTC

Surgical management of giant pituitary neuroendocrine tumors: Meta-analysis and consensus statement on behalf of the EANS skull base section – Brain and Spine

NCCN Guideline | Rectal cancer.

19 Oct, 2022 | 14:25h | UTC

Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Consensus Recommendations | Radiation therapy in oligometastatic prostate cancer.

19 Oct, 2022 | 14:24h | UTC

Recommendations for Radiation Therapy in Oligometastatic Prostate Cancer: an ESTRO-ACROP Delphi consensus – Radiotherapy & Oncology

Cohort Study | 3-year outcomes of patients with spontaneous coronary artery dissection.

19 Oct, 2022 | 14:23h | UTC

Canadian Spontaneous Coronary Artery Dissection Cohort Study: 3-Year Outcomes – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Editorial: Spontaneous Coronary Artery Dissection: Lower Than Expected Recurrence Rate in a Large Prospective Canadian Cohort – Journal of the American College of Cardiology

Commentary: SCAD Heart Attacks: Outcomes Not as Bad as Previously Feared – Daytonews

M-A | Interventions associated with reduced loneliness and social isolation in older adults.

19 Oct, 2022 | 14:22h | UTC

Interventions Associated With Reduced Loneliness and Social Isolation in Older Adults: A Systematic Review and Meta-analysis – JAMA Network Open

Loneliness and health – Nature Reviews Disease Primers (if the link is paywalled, try this one)

AHA Scientific Statement | Effects of objective and perceived social isolation on cardiovascular and brain health.

The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ

Social Isolation and Loneliness – World Health Organization

Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA

Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women – Heart

Review | Anesthetic considerations for endovascular treatment in stroke therapy.

19 Oct, 2022 | 14:20h | UTC

Anesthetic considerations for endovascular treatment in stroke therapy – Current Opinion in Anaesthesiology

Systematic Review | Antihistamines to prevent and treat motion sickness.

19 Oct, 2022 | 14:21h | UTC

Antihistamines for motion sickness – Cochrane Library

Summary: Antihistamines to prevent and treat motion sickness – Cochrane Library

Commentary on Twitter

New from Cochrane Evidence: Antihistamines are likely to reduce the risk of developing motion sickness in susceptible adults under normal conditions, e.g. traveling by car or boat, but they may be more likely to cause drowsiness than placebo https://t.co/l3gtX9ad7T… pic.twitter.com/EcQZYmwMrU

— Cochrane ENT (@CochraneENT) October 17, 2022

Pneumonia update for emergency clinicians.

19 Oct, 2022 | 14:19h | UTC

Pneumonia Update for Emergency Clinicians – Current Emergency and Hospital Medicine Reports

Cohort Study | ARBs linked to decreased incidence of epilepsy compared with other antihypertensives.

19 Oct, 2022 | 14:18h | UTC

Association Between Angiotensin Receptor Blocker Therapy and Incidence of Epilepsy in Patients With Hypertension – JAMA Neurology (free for a limited period)

Loneliness and health – Nature Reviews Disease Primers (if the link is paywalled, try this one)

AHA Scientific Statement | Effects of objective and perceived social isolation on cardiovascular and brain health.

The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ

Social Isolation and Loneliness – World Health Organization

Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA

Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women – Heart

Phase 2 RCT | Efficacy of adjunctive D-Cycloserine to intermittent theta-burst stimulation for major depressive disorder.

19 Oct, 2022 | 14:16h | UTC

Efficacy of Adjunctive D-Cycloserine to Intermittent Theta-Burst Stimulation for Major Depressive Disorder: A Randomized Clinical Trial – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries:

Effectiveness of iTBS for Major Depression May Be Improved by Addition of D-Cycloserine – Psychiatric News Alert

Adjunctive D-Cycloserine Improves Efficacy of Brain Stimulation in Patients with MDD – Consultant 360

Commentary on Twitter

In this RCT w 50 participants, those receiving intermittent theta-burst stimulation w adjunctive D-Cycloserine had significantly greater improvements in depressive symptoms compared to stimulation w placebo. https://t.co/AnP93WnkdG #Research

— JAMA Psychiatry (@JAMAPsych) October 12, 2022