Daily Archives: September 8, 2022
Cluster RCT | Umbilical cord milking may improve health in non-vigorous term and near-term infants.
8 Sep, 2022 | 14:47h | UTCNews Release: Umbilical cord milking may improve health in non-vigorous term and near-term infants – NIH News Releases
Original Study: Umbilical cord milking in non-vigorous infants: A cluster-randomized crossover trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentary on Twitter
Does milking the umbilical cord benefit infants non-vigorous at birth?
A new RCT by @NeoAnup published in @AJOG_thegray evaluates this https://t.co/M5RRAzdEHz#neoEBM #neoTwitter #EBNEOAlerts pic.twitter.com/mZnSKjcGNt
— Evidence-Based Neo (@EBNEO) August 20, 2022
Study suggests many stable patients with ST-Elevation Myocardial Infarction may not require routine admission to a cardiac intensive care unit following PCI reperfusion.
8 Sep, 2022 | 14:45h | UTC
Early versus delayed non–vitamin k antagonist oral anticoagulant therapy after acute ischemic stroke in atrial fibrillation: a registry-based randomized controlled noninferiority study.
8 Sep, 2022 | 14:46h | UTCEarly Versus Delayed Non–Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): A Registry-Based Randomized Controlled Noninferiority Study – Circulation (free for a limited period)
Commentary on Twitter
Congrats to my good friend/colleague @BoNorrving for the TIMING study! Starting NOAC after stroke d/t AF <4 d is safe (no ICH) and = or better than 5-10 d. Registry-based, pragmatic, investigator led, PROBE design. High value = science first approach.
https://t.co/35qiZ5Ivoa— Dr. Lee Schwamm (@Braindoc_MGH) September 7, 2022
Cohort Study | Long-term cardiac pathology in individuals with mild initial COVID-19 illness.
8 Sep, 2022 | 14:44h | UTCLong-term cardiac pathology in individuals with mild initial COVID-19 illness – Nature Medicine
Review | COVID-19 in children.
8 Sep, 2022 | 14:43h | UTCCOVID-19 in Children – Pediatric Clinics of North America
Guideline Summary | Management of patients with suspected or confirmed antibiotic allergy.
8 Sep, 2022 | 14:42h | UTCRelated:
M-A: Most patients with allergy to Penicillin can be given Cefazolin
Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy
Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule
NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk
International consensus statement on obstructive sleep apnea.
8 Sep, 2022 | 14:41h | UTCInternational consensus statement on obstructive sleep apnea – Allergy & Rhinology (PDF)
Guideline | Management and maintenance of echocardiography equipment.
8 Sep, 2022 | 14:40h | UTC
Systematic Review | Reexamining the role of postoperative ICU admission for patients undergoing elective craniotomy.
8 Sep, 2022 | 14:38h | UTCReexamining the Role of Postoperative ICU Admission for Patients Undergoing Elective Craniotomy: A Systematic Review – Critical Care Medicine (free for a limited period)
Commentary on Twitter
Optimizing healthcare resources is more important now than ever
Reviewing 2,469 patients, @tdazad @pav_shah+ found only 2.1% of elective craniotomies triaged to non-ICU required care escalation, potential huge savings
See the full results @CritCareMed:https://t.co/uJu3gXolD6 pic.twitter.com/wQuKes9hpn
— Johns Hopkins Neuro-Oncology Surgical Outcomes Lab (@NeuroOncSurgery) June 12, 2022
Casting light on the necessary, expansive, and evolving role of the critical care dietitian: an essential member of the critical care team.
8 Sep, 2022 | 14:39h | UTCCasting Light on the Necessary, Expansive, and Evolving Role of the Critical Care Dietitian: An Essential Member of the Critical Care Team – Critical Care Medicine (free for a limited period)
Commentary on Twitter
Patel et al: #ICUdietician valuable shared resource w' evolving & expanding need in #CritCareMed
?Expert perspectives #ICUnutrition
Link: https://t.co/OyEQSQdJde@SCCM @PedCritCareMed @CritCareExplore pic.twitter.com/mt7Z9lf2WZ
— Critical Care Medicine (@CritCareMed) August 31, 2022
RCT | Sulopenem (it has both IV and oral formulations) did not meet the criteria for noninferiority compared to Ertapenen for treating complicated urinary tract infections, including pyelonephritis.
8 Sep, 2022 | 14:37h | UTC
Systematic Review | Chest physiotherapy for pneumonia in adults.
8 Sep, 2022 | 14:36h | UTCChest physiotherapy for pneumonia in adults – Cochrane Library
Summary: Chest physiotherapy for pneumonia in adults – Cochrane Library
Systematic Review | Hypoxia‐inducible factor stabilizers for the anemia of chronic kidney disease.
8 Sep, 2022 | 14:35h | UTCHypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease – Cochrane Library
RCT | Lenalidomide-dexamethasone vs. observation in high-risk smoldering myeloma after 12 years of median follow-up time.
8 Sep, 2022 | 14:34h | UTCLenalidomide-dexamethasone versus observation in high-risk smoldering myeloma after 12 years of median follow-up time: A randomized, open-label study – European Journal of Cancer (link to abstract – $ for full-text)
Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomized ODYSSEY trial.
8 Sep, 2022 | 14:33h | UTC
Commentary on Twitter
New: Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomised ODYSSEY trial by Pauline Amuge @bayloruganda and colleagues @MRCCTU https://t.co/mc1jWSXMU2 #openaccess pic.twitter.com/A10LgZcwjF
— The Lancet HIV (@TheLancetHIV) September 1, 2022
Review | The management of hypertensive emergencies—is there a “magical” prescription for all?
8 Sep, 2022 | 14:32h | UTC
Perspective | Psychedelic drugs take on depression.
8 Sep, 2022 | 14:32h | UTCPsychedelic drugs take on depression – Nature
Pediatric infective endocarditis: a literature review.
8 Sep, 2022 | 14:31h | UTCPediatric Infective Endocarditis: A Literature Review – Journal of Clinical Medicine
48-week follow-up of a RCT | Pegcetacoplan vs. Eculizumab in patients with paroxysmal nocturnal hemoglobinuria.
8 Sep, 2022 | 14:29h | UTCPegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial – The Lancet Haematology (link to abstract – $ for full-text)
Original Study: Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria – New England Journal of Medicine
Commentary on Twitter (thread – click for more)
NEW research—Duration of improved haem outcomes and favourable safety over 48 weeks suggests that pegcetacoplan has the potential to alter treatment goals in patients with paroxysmal nocturnal haemoglobinuria: long-term results of PEGASUS #PNH https://t.co/dpT5cDih8X
— The Lancet Haematology (@TheLancetHaem) September 1, 2022
Review | Lung sonography in critical care medicine.
8 Sep, 2022 | 14:30h | UTCLung Sonography in Critical Care Medicine – Journal of Clinical Medicine
Severe prognoses for intracerebral and intraventricular hemorrhage may greatly underestimate functional recovery.
8 Sep, 2022 | 14:28h | UTCOriginal Study: One-Year Outcome Trajectories and Factors Associated with Functional Recovery Among Survivors of Intracerebral and Intraventricular Hemorrhage With Initial Severe Disability – JAMA Neurology (link to abstract – $ for full-text)
Commentary on Twitter
In this cohort study, nearly half of the survivors of intracerebral hemorrhage with poor-outcome in the early-phase recovered to a good outcome by 1-year. Including first 30-day events in prognostic models improved prediction of recovery. https://t.co/uQ7IqxCqBD
— JAMA Neurology (@JAMANeuro) July 25, 2022
Study shows bariatric surgery is more effective than lifestyle for type 2 diabetes remission.
8 Sep, 2022 | 14:27h | UTCNews Release: Bariatric surgery more effective than lifestyle for type 2 diabetes remission – Pennington Biomedical Research Center
Original Study: Diabetes Remission in the Alliance of Randomized Trials of Medicine Versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) – Diabetes Care
M-A | Effect of high-flow nasal oxygen on hypoxemia during procedural sedation.
8 Sep, 2022 | 14:26h | UTC
M-A | Hypocalcemia following thyroidectomy among patients who have previously undergone bariatric surgery.
8 Sep, 2022 | 14:25h | UTCHypocalcaemia following thyroidectomy among patients who have previously undergone bariatric surgery: systematic review and meta-analysis – British Journal of Surgery (link to abstract – $ for full-text)
RCT | Ripretinib vs. Sunitinib in patients with advanced gastrointestinal stromal tumor after treatment with imatinib.
8 Sep, 2022 | 14:24h | UTC
Commentary on Twitter
? INTRIGUE Trial: Ipretinib not superior to sunitinib but demonstrates longest median progression free survival ever in advanced #GastrointestinalStromalTumor ➡️ https://t.co/aUNdvXaQcH #GIST #scmsm @seppobauer pic.twitter.com/pPfph6A8Lr
— Journal of Clinical Oncology (@JCO_ASCO) August 24, 2022