Daily Archives: August 30, 2022
#ESCCongress – M-A | Radial access for coronary interventions confers lower mortality than femoral access.
30 Aug, 2022 | 12:17h | UTCNews Release: Radial access for coronary interventions confers lower mortality than femoral access – European Society of Cardiology
Original Study: Impact on Mortality and Major Bleeding of Radial Versus Femoral Artery Access for Coronary Angiography or Percutaneous Coronary Intervention: a Meta-analysis of Individual Patient Data from Seven Multicenter Randomized Clinical Trials – Circulation (free for a limited period)
Commentary: Less Death, Major Bleeding With Transradial Access: Meta-analysis – TCTMD
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In a individual-level meta-analysis of 21,600 patients undergoing coronary angiography, radial approach was associated with ⬇️ all-cause mortality (1.5 vs 2.1%) and ⬇️… @GargiuloG83 @vlgmrc @DanieleGiacoppo @SVRaoMD https://t.co/aOJ7ZgaJmK pic.twitter.com/gbWzUNTQck
— Circulation (@CircAHA) August 29, 2022
#ESCCongress | Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomized, double-blind trials.
30 Aug, 2022 | 12:16h | UTCNews Release: Cardiovascular protection from statins greatly outweighs the risk of muscle symptoms – European Society of Cardiology
Commentary: Only Very Small Risk of Muscle Symptoms With Statins: CTT Collaboration – TCTMD
#ESCCongress – Meta-analysis of randomized trials | Angiotensin receptor blockers and Beta-blockers in Marfan syndrome: an individual patient data meta-analysis of randomized trials.
30 Aug, 2022 | 12:15h | UTCNews Release: Drug combination may delay need for surgery in patients with Marfan syndrome – TCTMD
Commentary: ARBs Halve Rate of Aortic Root Enlargement in Marfan: Meta-analysis – TCTMD
#ESCCongress – M-A | Patients with heart failure benefit from dapagliflozin regardless of ejection fraction.
30 Aug, 2022 | 12:14h | UTCNews Release: Patients with heart failure benefit from dapagliflozin regardless of ejection fraction – European Society of Cardiology
Related:
Consensus Statement | Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis.
30 Aug, 2022 | 12:10h | UTC
Commentary on Twitter
Lipoprotein(a) in atherosclerotic CV and aortic stenosis – a European Atherosclerosis Society consensus statement https://t.co/Bzzpd3Bx8M
#EHJ #ESCCongress #ESCYoung @escardio @ehj_ed @rladeiraslopes pic.twitter.com/ZcqaPe581K
— European Society of Cardiology Journals (@ESC_Journals) August 29, 2022
#ESCCongress | Study shows long-term Evolocumab appears to be safe in patients with established atherosclerotic cardiovascular disease.
30 Aug, 2022 | 12:12h | UTCNews Release: Long-term evolocumab therapy leads to further reductions in cardiovascular events – European Society of Cardiology
Original Article: Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease – New England Journal of Medicine
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In this open-label extension of #FOURIER RCT, long-term evolocumab therapy for >8 yrs was associated w/ persistently low rates and greater reduction in MACE compared w/ delayed treatment initiation among patients w… https://t.co/9g97s4MZSt pic.twitter.com/y5uN53gdKo
— Circulation (@CircAHA) August 29, 2022
Consensus statement on intraoperative and postoperative interventions to reduce pulmonary complications after esophagectomy.
30 Aug, 2022 | 12:09h | UTC
#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.
30 Aug, 2022 | 12:12h | UTCNews Release: Trial supports full-dose anticoagulation to prevent blood clots in COVID-19 patients – European Society of Cardiology
Related:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In the #COVID-PACT 2×2 factorial RCT, full-dose prophylactic anticoagulation, but not the addition of clopidogrel, reduced thrombotic complications but w/ increased bleeding among critically-ill patients w/ COVID-19 https://t.co/UNxFCIC5B9 pic.twitter.com/p5LGmpCGeL
— Circulation (@CircAHA) August 29, 2022
Guidelines | Treatment of symptomatic gallstone disease.
30 Aug, 2022 | 12:09h | UTC
Guideline | Management of medication overuse and medication overuse headache.
30 Aug, 2022 | 12:08h | UTC
RCT | Patient preference and treatment satisfaction with a port delivery system for Ranibizumab vs. intravitreal injections in patients with neovascular age-related macular degeneration.
30 Aug, 2022 | 12:06h | UTCCommentary: Port Delivery System Preferred Over Intravitreal Injection for Patients with nAMD – HCPLive
Commentary on Twitter
In the phase 3 Archway trial, mean overall treatment satisfaction scores were high in port delivery system & intravitreal injection arms; pts with neovascular AMD preferred treatment via the PDS with ranibizumab vs previous intravitreal injections https://t.co/NYf0aKpKaD
— JAMA Ophthalmology (@JAMAOphth) August 25, 2022
Meta analysis of randomized trials | Association of PD-L1 expression and other variables with benefit from immune checkpoint inhibition in advanced gastroesophageal cancer.
30 Aug, 2022 | 12:07h | UTCAssociation of PD-L1 Expression and Other Variables With Benefit From Immune Checkpoint Inhibition in Advanced Gastroesophageal Cancer: Systematic Review and Meta-analysis of 17 Phase 3 Randomized Clinical Trials – JAMA Oncology (free for a limited period)
Commentary on Twitter
In this meta-analysis of >11,000 patients with advanced gastroesophageal cancer, tissue PD-L1 expression — more than other variables besides microsatellite-high — identified varying degrees of benefit from immunotherapy-containing therapy. https://t.co/oUEDIEqLFj
— JAMA Oncology (@JAMAOnc) August 25, 2022
Single-center RCT | Effectiveness of intrarectal povidone-iodine cleansing plus formalin disinfection of the needle tip in decreasing infectious complications after transrectal prostate biopsy.
30 Aug, 2022 | 12:05h | UTCEffectiveness of Intrarectal Povidone-Iodine Cleansing plus Formalin Disinfection of the Needle Tip in Decreasing Infectious Complications after Transrectal Prostate Biopsy: A Randomized Controlled Trial – The Journal of Urology (link to abstract – $ for full-text)
Review | Therapeutic payload delivery to the myocardium: Evolving strategies and obstacles.
30 Aug, 2022 | 12:04h | UTCTherapeutic payload delivery to the myocardium: Evolving strategies and obstacles – JTCVS Open
Review | Invasive and noninvasive cardiovascular monitoring options for cardiac surgery.
30 Aug, 2022 | 12:03h | UTCInvasive and noninvasive cardiovascular monitoring options for cardiac surgery – JTCVS Open
Meta-analysis of observational studies | In patients with hepatocellular carcinoma, intraoperative blood salvage during liver transplantation appears safe.
30 Aug, 2022 | 12:03h | UTC
Salt substitutes vs. regular salt: a quick look.
30 Aug, 2022 | 12:02h | UTCSalt substitutes vs. regular salt: a quick look – Evidently Cochrane
Original Study: Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library
Related:
Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
Commentary on Twitter
https://twitter.com/CochraneLibrary/status/1563130897159028737
M-A | Utility of the Ages and Stages Questionnaire to identify developmental delay in children aged 12 to 60 months.
30 Aug, 2022 | 12:00h | UTCUtility of the Ages and Stages Questionnaire to Identify Developmental Delay in Children Aged 12 to 60 Months: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
Case series of acute cholecystitis associated with the use of Glucagon-Like Peptide-1 Receptor agonists reported to the US Food and Drug Administration.
30 Aug, 2022 | 11:59h | UTCAcute Cholecystitis Associated With the Use of Glucagon-Like Peptide-1 Receptor Agonists Reported to the US Food and Drug Administration – JAMA Internal Medicine (free for a limited period)
RCT | Colorectal Endoscopic Stenting Trial (CReST) for obstructing left-sided colorectal cancer.
30 Aug, 2022 | 11:58h | UTC
Cohort Study | Outcomes of patients with sporadic non-functioning pancreatic neuroendocrine neoplasms no larger than 2 cm under active surveillance.
30 Aug, 2022 | 11:57h | UTC
Development and external validation of DISPAIR fistula risk score for clinically relevant postoperative pancreatic fistula risk after distal pancreatectomy.
30 Aug, 2022 | 11:56h | UTC
M-A | Midodrine for the prevention of vasovagal syncope.
30 Aug, 2022 | 11:56h | UTCRelated: RCT: Midodrine can reduce the recurrence of vasovagal syncope.
Cohort Study | Comparing kidney health outcomes in children, adolescents, and adults with focal segmental glomerulosclerosis.
30 Aug, 2022 | 11:53h | UTC
Commentary on Twitter
https://twitter.com/JAMANetworkOpen/status/1562922771730305030
M-A | Urban-rural differences in hypertension prevalence in low-income and middle-income countries, 1990–2020.
30 Aug, 2022 | 11:55h | UTCNews Release: Study shows urban-rural differences in hypertension prevalence in low-income and middle-income countries – News Medical
Commentary on Twitter
🚨paper alert! In LMICs, is #hypertension more prevalent in urban or rural areas?
Nearly 300 studies from 66 LMICs (>19 million participants) revealed that the rate of change from 1990-2022 appears greater in rural.
It has been so nice contributing to this tremendous work!🤩 https://t.co/EjbRpf83HJ
— Adna Curto (@adna_otti) August 27, 2022