Daily Archives: June 20, 2022
WHO Situation Update: Multi-country monkeypox outbreak.
20 Jun, 2022 | 10:45h | UTCMulti-country monkeypox outbreak: situation update – World Health Organization
Related:
Monkeypox Genital Lesions – New England Journal of Medicine
Monkeypox vaccination begins — can the global outbreaks be contained? – Nature
Incubation period for monkeypox: Estimates from the Netherlands.
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
Rename monkeypox strains to remove geographic stigma, researchers say – Science
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
WHO report highlights urgent need to transform mental health and mental health care.
20 Jun, 2022 | 10:47h | UTCNews Release: WHO highlights urgent need to transform mental health and mental health care – World Health Organization
Report: World mental health report: Transforming mental health for all – World Health Organization
Commentary: Urgent Need to Transform Mental Health Care – WHO Says In Largest Review Ever – Health Policy Watch
Commentary on Twitter (thread – click for more)
WHO calls on all stakeholders to work together to deepen the value and commitment given to #MentalHealth, reshape the environments that influence mental health and strengthen the systems that care for people’s mental health: WHO #WorldMentalHealthReport https://t.co/J856BrylBB
— World Health Organization (WHO) (@WHO) June 17, 2022
RCT: A restrictive intravenous fluid strategy does not improve outcomes in ICU patients with septic shock.
20 Jun, 2022 | 10:51h | UTCRestriction of Intravenous Fluid in ICU Patients with Septic Shock – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: No Fewer Deaths Seen With Restricted IV Fluid for Septic Shock – HealthDay
Related:
Fluid administration and monitoring in ARDS: which management? – Intensive Care Medicine
Commentary on Twitter
In this trial, a restrictive approach to intravenous fluid administration in critically ill patients with septic shock did not reduce mortality. #CCR22 https://t.co/UfY1936Qwb pic.twitter.com/FtSaDIIroj
— NEJM (@NEJM) June 17, 2022
WHO Interim statement on decision-making considerations for the use of variant updated COVID-19 vaccines.
20 Jun, 2022 | 10:42h | UTCSee also: Interim statement on the composition of current COVID-19 vaccines – World Health Organization
Commentary on Twitter (thread – click for more)
Current #COVID19 vaccines provide high levels of protection against severe disease and death from all variants. They should continue to be used.
? interim statement:https://t.co/bVzzx1HnG2 pic.twitter.com/CJlAJqFr3C
— World Health Organization (WHO) (@WHO) June 17, 2022
Opinion | Normalizing menopause – “Martha Hickey and colleagues argue that social and cultural attitudes contribute to the varied experience of menopause and that medicalization fuels negative perceptions”.
20 Jun, 2022 | 10:38h | UTCNormalizing menopause – The BMJ (free for a limited period)
News Release: Medicalizing menopause may be unhelpful for some women – British Medical Journal
Commentary: Menopause is not a disease. Experts call for new narrative for this natural stage of a woman’s life – CNN
Cohort Study: Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes.
20 Jun, 2022 | 10:36h | UTC
Commentary on Twitter
Still remember working on this in 2019 but it's out today!
Gamma-GT level has a strong association with mortality outcomes and could add to the prediction of CV mortality
https://t.co/0lzqGfgiGc pic.twitter.com/C8tSZLWlI2— Fred Ho (@fredho42) May 13, 2022
Under a CC BY-NC-ND 4.0 license
Consensus Study: A core outcome set for post-COVID-19 condition in adults for use in clinical practice and research.
20 Jun, 2022 | 10:31h | UTCNews Release: Key outcomes of Long COVID identified in international consensus study – King’s College London
Invited Commentary: Post-COVID-19 condition in children: a COS is urgently needed – The Lancet Respiratory Medicine
Commentary on Twitter
NEW POSITION PAPER—A core outcome set for post-COVID-19 condition in adults for use in clinical practice and research
From Daniel Munblit & co https://t.co/zAxQ1ww6bT pic.twitter.com/WIitohP3Xo
— The Lancet Respiratory Medicine (@LancetRespirMed) June 15, 2022
Clues to long Covid: Scientists strive to unravel what is driving disabling symptoms.
20 Jun, 2022 | 10:30h | UTC
Case-control study: Risk of long COVID associated with delta vs. omicron variants of SARS-CoV-2.
20 Jun, 2022 | 10:34h | UTCRisk of long COVID associated with delta versus omicron variants of SARS-CoV-2 – The Lancet
News Release: Long COVID risk less during Omicron compared to Delta, study finds – King’s College London
Commentaries:
Omicron less likely to lead to long COVID, study finds – CIDRAP
Covid-19: Long covid risk is lower with omicron than delta, researchers find – The BMJ
Commentary on Twitter
Substantial (~50-75%) reduction of #LongCovid with Omicron compared with Delta variant, magnitude influenced by age and time since vaccination @TheLancet https://t.co/shAzJn8WSj pic.twitter.com/bXoct0sXd1
— Eric Topol (@EricTopol) June 17, 2022
Review, Statements, and Recommendations: Cuffless blood pressure measuring devices.
20 Jun, 2022 | 01:26h | UTCRelated:
[Preprint] Open-label RCT: Baricitinib noninferior to Tocilizumab in hospitalized patients with severe COVID-19.
20 Jun, 2022 | 10:28h | UTCRelated:
WHO recommends two new drugs to treat COVID-19 – World Health Organization
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 – New England Journal of Medicine
Commentary on Twitter
Preprint⚡⚡
Baricitinib Vs Tocilizumab open label RCT
Baricitinib was non-inferior to tocilizumab with regards to the composite outcome of mechanical ventilation or death by day 28 and the time to discharge by day 28 in patients with severe #COVID19 https://t.co/sQkhATkjEd— Antibiotic Steward Bassam Ghanem?? (@ABsteward) June 16, 2022
Consensus Recommendations: Management of the congenital solitary kidney.
20 Jun, 2022 | 01:25h | UTC
NCCN Updated Guideline: Breast cancer.
20 Jun, 2022 | 01:24h | UTC
The clinician’s guide to prevention and treatment of osteoporosis.
20 Jun, 2022 | 01:22h | UTCThe clinician’s guide to prevention and treatment of osteoporosis – Osteoporosis International
Acute shortage of iodinated contrast media: implications and guidance for neurovascular imaging and intervention.
20 Jun, 2022 | 01:20h | UTCRelated Guidance:
Short-, Mid-, and Long-Term Strategies to Manage the Shortage of Iohexol – Radiology
Related Study:
Comparison of Strategies to Conserve Iodinated Intravascular Contrast Media for Computed Tomography During a Shortage – JAMA (free for a limited period) AND News Release: Amid Global Shortage, Study Shows How to Cut Contrast Dye Use 83% – University of California, San Francisco (UCSF)
Systematic Review: Rituximab for thyroid‐associated ophthalmopathy.
20 Jun, 2022 | 01:16h | UTCRituximab for thyroid‐associated ophthalmopathy – Cochrane Library
Perspective | Cardiovascular meta-analyses: fool’s gold or gold for fools?
20 Jun, 2022 | 01:15h | UTCCardiovascular meta-analyses: fool’s gold or gold for fools? – European Heart Journal
Brief Review: Helmet noninvasive support in hypoxemic respiratory failure.
20 Jun, 2022 | 01:13h | UTCHelmet noninvasive support in hypoxemic respiratory failure – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Helmet noninvasive support in hypoxemic respiratory failure:
⚙️ set‐up
⛑ physiology of helmet interface: from most relevant feature to major drawbacks
? clinical implications
Free to read #FOAMcc on @yourICM
? https://t.co/qNE4Id5oBg pic.twitter.com/b2auLLlW9z— Intensive Care Medicine (@yourICM) June 18, 2022
Prospective head-to-head comparative study: Functional stress imaging to predict abnormal coronary fractional flow reserve.
20 Jun, 2022 | 01:10h | UTC
Commentary on Twitter
Functional stress imaging to predict abnormal coronary fractional flow reserve: new insights from the PACIFIC 2 study!https://t.co/5N0dOW2Rem#PET #MRI #FFR #CCS #coronary #cardiotwitter @escardio @ESC_Journals pic.twitter.com/WCoA0cOgd9
— EHJ Editor-in-Chief (@ehj_ed) June 17, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
Systematic Review: Clinical judgement by primary care physicians for the diagnosis of all‐cause dementia or cognitive impairment in symptomatic people.
20 Jun, 2022 | 01:18h | UTCSummary: Why is improving dementia diagnosis important? – Cochrane Library
Single-arm phase 3 Trial: Onasemnogene abeparvovec for presymptomatic infants with three copies of SMN2 at risk for spinal muscular atrophy.
20 Jun, 2022 | 01:04h | UTC
Commentary on Twitter
For infants with three copies of #SMN1 at risk for #SMA type 1, onasemnogene abeparvovec improves ventilator-free survival and nutritional/respiratory independence and allows motor development similar to healthy children without SMA. #2022SMAConferencehttps://t.co/tIsR1fByNK
— Nature Medicine (@NatureMedicine) June 17, 2022
RCT: Immune enhancement with Thymosin alpha 1 does not improve outcomes in patients with predicted severe acute necrotizing pancreatitis.
20 Jun, 2022 | 01:11h | UTCImmune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial – Intensive Care Medicine (if the link is paywalled, try this one)
RCT: Safety and efficacy of Eptinezumab for migraine prevention in patients with two-to-four previous preventive treatment failures.
20 Jun, 2022 | 01:01h | UTCSafety and efficacy of eptinezumab for migraine prevention in patients with two-to-four previous preventive treatment failures (DELIVER): a multi-arm, randomised, double-blind, placebo-controlled, phase 3b trial – The Lancet Neurology (link to abstract – $ for full-text)
Artificial intelligence may detect autism speech patterns across different languages, study finds.
20 Jun, 2022 | 01:05h | UTCNews Release: AI detects autism speech patterns across different languages – Northwestern University
Original Study: Cross-linguistic patterns of speech prosodic differences in autism: A machine learning study – PLOS One
Cardiac xenotransplantation: challenges, evolution, and advances.
20 Jun, 2022 | 00:58h | UTCCommentary: Many Hurdles to Clear Before Cardiac Xenotransplantation Takes Off – TCTMD
Related:
In 1st, US surgeons transplant pig heart into human patient – Associated Press
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation – New England Journal of Medicine (link to abstract – $ for full-text)
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight – STAT