Daily Archives: May 23, 2022
Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update.
23 May, 2022 | 01:58h | UTC
Commentary on Twitter
Just published ?? @ICHEJournal @SHEA_Epi @IDSAInfo @APIC
Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update #IDTwitter https://t.co/fipGfkyHi6 pic.twitter.com/c88X5GL0d6— Antibiotic Steward Bassam Ghanem?? (@ABsteward) May 20, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
NICE rapid guideline update on the management of Covid-19.
23 May, 2022 | 01:56h | UTCCOVID-19 rapid guideline: managing COVID-19 – National Institute for Health and Care Excellence
RCT: Safety and immunogenicity of heterologous boost immunization with an orally administered aerosolized Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults.
23 May, 2022 | 01:54h | UTC
Commentary on Twitter
Mix-and-match typically refers to different shots. Here's a randomized trial of shots and an oral vaccine that ameliorates the immune responsehttps://t.co/FFWHEwS37Y @LancetRespirMed pic.twitter.com/JZyvrxCalS
— Eric Topol (@EricTopol) May 21, 2022
RCT: High-flow nasal oxygen is not beneficial for patients with COVID-19 pneumonia and mild hypoxemia.
23 May, 2022 | 01:51h | UTC
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both?
23 May, 2022 | 01:48h | UTCWhat’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Related:
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
WHO: Multi-country monkeypox outbreak in non-endemic countries.
23 May, 2022 | 01:46h | UTCMulti-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
Commentary on Twitter
The WHO has started to report data on the monkeypox outbreak: https://t.co/e3Q23sllvX pic.twitter.com/3WKqj79eLy
— Max Roser (@MaxCRoser) May 22, 2022
Review: Hypothyroidism.
23 May, 2022 | 01:49h | UTCHypothyroidism – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Infographic: Hypothyroidism – Nature Reviews Disease Primers (if the link is paywalled, try this one)
NCCN Clinical Practice Guidelines in Oncology: 2022 Updates.
23 May, 2022 | 01:37h | UTCNCCN Clinical Practice Guidelines in Oncology: 2022 Updates – The ASCO Post
Expert Consensus: Treatment of coronary bifurcation lesions.
23 May, 2022 | 01:36h | UTC
Commentary on Twitter
Coinciding with the beginning of #EuroPCR, the 16th Expert Consensus Document of the European Bifurcation Club is online ahead of print with two publications: Part 1 on the provisional pathway and Part 2 on two-stent strategies. https://t.co/cfECcOi0GJhttps://t.co/gjUrYKV2qK pic.twitter.com/IlX8GhKLQU
— Davide Capodanno (@DFCapodanno) May 15, 2022
Management of moderate to severe traumatic brain injury: an update for the intensivist.
23 May, 2022 | 01:42h | UTC
Commentary on Twitter
Management of moderate to severe TBI
⏳ first hours: initial #resuscitation targets
?? in #ICU, ⬇️ secondary insults after trauma: ICP, CPP, hemodynamics
? multimodality monitoring targets & management
? extracranial complications
? long‐term outcomehttps://t.co/do6a3Fe5vs pic.twitter.com/uGxxfI5hOZ— Intensive Care Medicine (@yourICM) May 21, 2022
Clinical trial registration patterns and changes in primary outcomes of randomized clinical trials from 2002 to 2017.
23 May, 2022 | 01:34h | UTCClinical Trial Registration Patterns and Changes in Primary Outcomes of Randomized Clinical Trials From 2002 to 2017 – JAMA Internal Medicine (free for a limited period)
Commentary on Twitter
This study of 146,462 full-text RCTs found that up to 32% of published trials reported a registry number, and almost 15% of these made substantial changes in primary outcome registration within study duration. Practices have improved over the years. https://t.co/JnXrEpp00J
— JAMA Internal Medicine (@JAMAInternalMed) May 17, 2022
Systematic Review: Prehabilitation vs. no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery.
23 May, 2022 | 01:31h | UTCSummary: Preparing a patient with bowel cancer for surgery with multiple interventions – Cochrane Library
Systematic Review: Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting.
23 May, 2022 | 01:29h | UTC
Drugs for agitation in people with dementia: benefits and risks.
23 May, 2022 | 01:25h | UTCDrugs for agitation in people with dementia: benefits and risks – Evidently Cochrane
Original Study: Antipsychotics for agitation and psychosis in people with Alzheimer’s disease and vascular dementia – Cochrane Library
Commentary on Twitter (thread – click for more)
New blog for #DementiaActionWeek: https://t.co/UT1sdwNZRv @CharSquires & @jamie_garr look at the @CochraneDCIG evidence on drugs used to treat agitation & psychosis in people with #dementia & reflect on what doctors & families may want to consider when making treatment decisions pic.twitter.com/Ei7njr3ynL
— Cochrane UK (@CochraneUK) May 20, 2022
Preventing dementia: what’s the evidence?
23 May, 2022 | 01:27h | UTCPreventing dementia: what’s the evidence? – Evidently Cochrane
Cohort Study: Association of thyroid hormone treatment intensity with cardiovascular mortality.
23 May, 2022 | 01:23h | UTCCommentaries:
Thyroid Hormone Treatment Intensity and Cardiovascular Mortality – American College of Cardiology
Thyroid Hormone Treatment Intensity May Be Modifiable Risk Factor for CV Mortality – HCP Live
Commentary on Twitter
In this cohort study of US Veterans on thyroid hormone therapy, both exogenous hyperthyroidism and hypothyroidism contributed to the increased risk of cardiovascular mortality after adjusting for demographic and traditional cardiovascular risk factors. https://t.co/NO4776Ia4m
— JAMA Network Open (@JAMANetworkOpen) May 12, 2022
12 plagues of AI in healthcare: a practical guide to current issues with using machine learning in a medical context.
23 May, 2022 | 01:21h | UTC
Definitions and standardized endpoints for treatment of coronary bifurcations.
23 May, 2022 | 01:18h | UTCDefinitions and Standardized Endpoints for Treatment of Coronary Bifurcations – EuroIntervention
Commentary on Twitter
There is a paucity of standardization and comparability across studies involving coronary bifurcation lesions. The BIF-ARC document (first joint publication of @EuroInterventio and @JACCJournals) provides definitions and criteria for use in such studies.https://t.co/HyCHitD2CI pic.twitter.com/uSn2eSTMyo
— Davide Capodanno (@DFCapodanno) May 18, 2022
QRS micro-fragmentation as a mortality predictor.
23 May, 2022 | 01:19h | UTCQRS micro-fragmentation as a mortality predictor – European Heart Journal
Editorial: The fractionated QRS complex for cardiovascular risk assessment – European Heart Journal
Commentary on Twitter
QRS micro-fragmentation as a mortality predictor: discover more in EHJ! https://t.co/P0gkPFpIs8#EKG #QRS #fragmentation #prediction #outcome #cardiotwitter @escardio @ESC_Journals pic.twitter.com/8IAIL3fXFF
— EHJ Editor-in-Chief (@ehj_ed) February 22, 2022
Under a https://creativecommons.org/licenses/by/4.0/ license
Observational study suggests hepatic arterial infusion pump chemotherapy may be an alternative to resection for patients with multifocal intrahepatic cholangiocarcinoma.
23 May, 2022 | 00:52h | UTCComparison of Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Patients With Multifocal Intrahepatic Cholangiocarcinoma – JAMA Surgery (link to abstract – $ for full-text)
Commentaries:
Treating iCCA With Chemo Pump Can Be as Effective as Surgery, JAMA Study Finds – AJMC
Commentaries on Twitter
This study found that resection of multifocal intrahepatic cholangiocarcinoma should be carefully considered. Hepatic artery infusion pump chemotherapy may be an effective treatment option. https://t.co/lp1KwSCJvi
— JAMA Surgery (@JAMASurgery) May 12, 2022
In this cohort study of 319 patients with multifocal intrahepatic cholangiocarcinoma, those treated with HAIP floxuridine chemotherapy had similar overall survival to those who underwent resection. @FlavioRochaMD @michael_lidsky @JAMASurgery @HopSTranCao @sepideh_gholami https://t.co/P7O3B7JLRo
— Syed A. Ahmad (@SyedAAhmad5) May 18, 2022
Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers.
23 May, 2022 | 01:16h | UTCCommentaries:
Commentary from the author on Twitter (thread – click for more)
Feasibility of clinical whole genome and transcriptome sequencing (WGTS) in oncology. A ? on our latest study published in Nature Communications today:https://t.co/6007GkYDAc
— Elli Papaemmanuil, PhD (@PapaemmanuilLab) May 18, 2022
Viewpoint: The imperative for diversity and inclusion in clinical trials and health research participation.
23 May, 2022 | 00:49h | UTC
Review: Tympanostomy tubes for children with acute otitis media.
23 May, 2022 | 00:46h | UTCTympanostomy tubes for children with acute otitis media – Canadian Family Physician
Cohort Study: Clinical features and natural history of preadolescent nonsyndromic hypertrophic cardiomyopathy.
23 May, 2022 | 00:45h | UTCCommentary: Clinical Features and Course of Preadolescent Hypertrophic Cardiomyopathy – American College of Cardiology
Review: Allergic asthma is a risk factor for human cardiovascular diseases.
23 May, 2022 | 00:48h | UTCAllergic asthma is a risk factor for human cardiovascular diseases – Nature Cardiovascular Research
Commentary on Twitter
A Review in @NatureCVR discusses how asthma and allied allergic conditions may contribute to the prevalence, incidence and progression of cardiovascular diseases and vice versa. https://t.co/6kRj9LvOfa pic.twitter.com/Ydq8X2k1rY
— Nature Portfolio (@NaturePortfolio) May 18, 2022