Daily Archives: May 13, 2022 | LinksMedicus Free Medical News & Perspectives

RCT: Multicomponent intervention to prevent mobility disability in frail older adults.

13 May, 2022 | 11:41h | UTC

Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project) – The BMJ

Editorial: Preserving community mobility in vulnerable older people – The BMJ

News Release: Regular exercise with dietary advice linked to better mobility in frail older people – BMJ Newsroom

Commentary on Twitter

A programme of regular exercise along with expert dietary advice is linked to a reduction in mobility problems among frail older people living in the community, finds this trial by @Emanuel00962649 and colleagueshttps://t.co/xT44sTwe4k

— The BMJ (@bmj_latest) May 12, 2022

Review of thoracic imaging manifestations of COVID-19 and other pathologic Coronaviruses.

13 May, 2022 | 11:36h | UTC

Review of Thoracic Imaging Manifestations of COVID-19 and Other Pathologic Coronaviruses – Radiology Clinics of North America

Explaining the unexplained hepatitis in children.

13 May, 2022 | 11:39h | UTC

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

New versions of Omicron are masters of immune evasion.

13 May, 2022 | 11:37h | UTC

New versions of Omicron are masters of immune evasion – Science

Commentary on Twitter

"Based on its immunological profile, it [Omicron & its subvariants] should be called SARS-3"https://t.co/zxV3T2SKIB @gretchenvogel @NewsfromScience
w/ @K_G_Andersen @Tuliodna @linfa_wang pic.twitter.com/ToKDqNGH74

— Eric Topol (@EricTopol) May 12, 2022

IDSA updates guidelines on the treatment and management of patients with COVID-19.

13 May, 2022 | 11:35h | UTC

IDSA Guidelines on the Treatment and Management of Patients with COVID-19 – Infectious Diseases Society of America

Cohort Study: Health outcomes in people 2 years after surviving hospitalization with COVID-19.

13 May, 2022 | 11:32h | UTC

Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study – The Lancet Respiratory Medicine

News Release: Two years after infection, half of people hospitalized with COVID-19 have at least one symptom, follow-up study suggests – Lancet

Clinical features of, and risk factors for, severe or fatal COVID-19 among people living with HIV admitted to hospital: analysis of data from the WHO Global Clinical Platform of COVID-19.

13 May, 2022 | 11:28h | UTC

Clinical features of, and risk factors for, severe or fatal COVID-19 among people living with HIV admitted to hospital: analysis of data from the WHO Global Clinical Platform of COVID-19 – The Lancet HIV

Invited Commentary: A collision of pandemics: HIV and COVID-19 – The Lancet HIV

Commentaries on Twitter

New: Clinical features of, and risk factors for, severe or fatal COVID-19 among people living with HIV admitted to hospital: analysis of data from the WHO Global Clinical Platform of COVID-19 by Silvia Bertagnolio and colleagues https://t.co/hAyuWi7fMN #openaccess pic.twitter.com/VmjeYMLPHu

— The Lancet HIV (@TheLancetHIV) May 11, 2022

Clinical features of, and risk factors for, severe or fatal COVID-19 among PLWH admitted to hospital…. https://t.co/KKVKwroy4Z Compared with individuals without HIV, PLWH (96% living in Africa) had 15% ⬆️ odds of severe COVID-19 and were 38% more likely to die in hospital.

— Carlos del Rio (@CarlosdelRio7) May 12, 2022

Canadian guidelines for peripheral arterial disease.

13 May, 2022 | 11:12h | UTC

Canadian Cardiovascular Society 2022 Guidelines for Peripheral Arterial Disease – Canadian Journal of Cardiology

Guide to enhanced recovery for cancer patients undergoing esophagectomy.

13 May, 2022 | 11:11h | UTC

Guide to Enhanced Recovery for Cancer Patients Undergoing Surgery: ERAS and Oesophagectomy – Annals of Surgical Oncology

Visual abstract: ASO Visual Abstract: Guide to Enhanced Recovery for Cancer Patients Undergoing Surgery—ERAS and Esophagectomy

See also: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (some guidelines are free)

[Preprint] Long Covid: A systematic review and meta-analysis of 120,970 patients.

13 May, 2022 | 11:30h | UTC

Long Covid: A Systematic Review and Meta-Analysis of 120,970 Patients – Preprints with The Lancet

Commentary on Twitter

A systematic #LongCovid review of nearly 200 studies and over 120,000 participants, reinforces the high frequency of symptoms > 6 months, not linked to severity of acute illness, and potential for marked disabilityhttps://t.co/9NYQT1P79G pic.twitter.com/WFzBqghbGI

— Eric Topol (@EricTopol) May 6, 2022

AUA/SMSNA Guideline: The diagnosis and management of priapism.

13 May, 2022 | 11:08h | UTC

The Diagnosis and Management of Priapism: an AUA/SMSNA Guideline (2022) – American Urological Association

AUA/ASTRO Guideline: Clinically localized prostate cancer.

13 May, 2022 | 11:10h | UTC

Homepage: Clinically Localized Prostate Cancer: AUA/ASTRO Guideline – American Urological Association

Part I: Introduction, Risk Assessment, Staging and Risk-Based Management

Part II: Principles of Active Surveillance, Principles of Surgery, and Follow-Up

Part III: Principles of Radiation and Future Directions

Systematic Review of Active Surveillance for Clinically Localised Prostate Cancer to Develop Recommendations Regarding Inclusion of Intermediate-risk Disease, Biopsy Characteristics at Inclusion and Monitoring, and Surveillance Repeat Biopsy Strategy – European Urology

Therapies for Clinically Localized Prostate Cancer: A Comparative Effectiveness Review – The Journal of Urology

High-dose radiotherapy and risk-adapted androgen deprivation in localised prostate cancer (DART 01/05): 10-year results of a phase 3 randomised, controlled trial – The Lancet Oncology

German S3 Evidence-Based Guidelines on Focal Therapy in Localized Prostate Cancer: The First Evidence-Based Guidelines on Focal Therapy – Urologia Internationalis

Therapies for Clinically Localized Prostate Cancer – Agency for Healthcare Research and Quality

Radical prostatectomy versus deferred treatment for localised prostate cancer – Cochrane Library

Nutritional recommendations for patients undergoing prolonged glucocorticoid therapy.

13 May, 2022 | 11:05h | UTC

Nutritional recommendations for patients undergoing prolonged glucocorticoid therapy – Rheumatology Advances in Practice

Commentary on Twitter

NEW: Narrative review from @esteves_gp @eimeardol et al summarises evidence regarding #nutritional recommendations during GC therapy and highlights gaps in the literature.
✅ Targeted nutritional strategies may help alleviate adverse effects of GCs.

? https://t.co/8NpIxkYmIv pic.twitter.com/RArjGTw6sA

— Rheumatology & Rheumatology Advances in Practice (@RheumJnl) April 22, 2022

AUA Guideline: Diagnosis and treatment interstitial cystitis/bladder pain syndrome.

13 May, 2022 | 11:07h | UTC

Diagnosis and Treatment Interstitial Cystitis/Bladder Pain Syndrome (2022) – American Urological Association

Skeletal infections: microbial pathogenesis, immunity, and clinical management.

13 May, 2022 | 11:03h | UTC

Skeletal infections: microbial pathogenesis, immunity and clinical management – Nature Reviews Microbiology (if the link is paywalled, try this one)

Review: Clinical trials in older people.

13 May, 2022 | 11:02h | UTC

Clinical trials in older people – Age and Ageing

M-A: Prevalence of burnout among GPs.

13 May, 2022 | 11:01h | UTC

Prevalence of burnout among GPs: a systematic review and meta-analysis – British Journal of General Practice

Viewpoint | How to Measure Progress in Addressing Physician Well-being: Beyond Burnout.

Physician Well-being 2.0: Where Are We and Where Are We Going?

Consensus Study – Taking Action Against Clinician Burnout: A Systems Approach to Professional Well-Being – National Academies of Medicine

[Abstract Only] Assessment of Risk Factors for Suicide Among US Health Care Professionals

Beyond Burnout: Docs Decry ‘Moral Injury’ From Financial Pressures of Health Care

Perspective: Hospital Administration Response to Physician Stress and Burnout

Opinion: It’s Time to Talk About Physician Burnout and Moral Injury

Systematic Review: Effect of Organization-Directed Workplace Interventions on Physician Burnout

Perspective: The 3 Causes Of Physician Burnout (And Why There’s No Simple Solution)

Physician Burnout: A Global Crisis (several resources on the subject)

Racial and ethnic disparities in estimated excess mortality from external causes in the US, March to December 2020.

13 May, 2022 | 10:57h | UTC

Racial and Ethnic Disparities in Estimated Excess Mortality From External Causes in the US, March to December 2020 – JAMA Internal Medicine (free for a limited period)

Editorial: The COVID-19 Pandemic and Racial and Ethnic Disparities in Estimated Excess Mortality From External Causes – JAMA Internal Medicine

Commentary on Twitter

In this study, American Indian or Alaska Native and Black populations experienced high rates or excess deaths from external causes (transportation fatalities homicide, and drug-related deaths) during the early #COIVD19 pandemic. https://t.co/RaatdoaFzI

— JAMA Internal Medicine (@JAMAInternalMed) May 11, 2022

Pharmacist-led review tied to better antimicrobial prescribing at discharge.

13 May, 2022 | 10:59h | UTC

Commentary: Pharmacist-led review tied to better antimicrobial prescribing at discharge – CIDRAP

Original Study: Pharmacist-Driven Transitions of Care Practice Model for Prescribing Oral Antimicrobials at Hospital Discharge – JAMA Network Open

Risk factors associated with Alzheimer disease and related dementias by sex and race and ethnicity in the US.

13 May, 2022 | 10:55h | UTC

Risk Factors Associated With Alzheimer Disease and Related Dementias by Sex and Race and Ethnicity in the US – JAMA Neurology (free for a limited period)

Commentaries:

Alzheimer’s and Dementia Linked to Eight Modifiable Risk Factors – Psychiatric News Alert

The 3 Midlife Factors That Raise Your Odds for Alzheimer’s – HealthDay

M-A: Impact of the WHO Surgical Safety Checklist relative to its design and intended use.

13 May, 2022 | 10:49h | UTC

Impact of the WHO Surgical Safety Checklist Relative to Its Design and Intended Use: A Systematic Review and Meta-Meta-Analysis – Journal of the American College of Surgeons

RCT: Treatment with Etirinotecan pegol for patients with metastatic breast cancer and brain metastases.

13 May, 2022 | 10:51h | UTC

Treatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases: Final Results From the Phase 3 ATTAIN Randomized Clinical Trial – JAMA Oncology (free for a limited period)

Commentary on Twitter

Treatment with etirinotecan pegol showed no statistically significant improvement in survival among patients with #BreastCancer & brain metastases, but study represents larged published study for this understudied population. https://t.co/AVKeo1BWQV #BCSM #BTSM

— JAMA Oncology (@JAMAOnc) May 12, 2022