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Daily Archives: April 29, 2022

RCT: Extended vs. standard antibiotic course duration in children below 5 years of age hospitalized with community-acquired pneumonia in high-risk settings.

29 Apr, 2022 | 11:16h | UTC

Extended Versus Standard Antibiotic Course Duration in Children <5 Years of Age Hospitalized With Community-acquired Pneumonia in High-risk Settings: Four-week Outcomes of a Multicenter, Double-blind, Parallel, Superiority Randomized Controlled Trial – The Pediatric Infectious Disease Journal

Related:

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA

Seven versus fourteen Days of Antibiotic Therapy for uncomplicated Gram-negative Bacteremia: a Non-inferiority Randomized Controlled Trial – Clinical Infectious Diseases

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

 

Commentary on Twitter

 

Review: Nutrition, longevity and disease: From molecular mechanisms to interventions.

29 Apr, 2022 | 11:18h | UTC

Nutrition, longevity and disease: From molecular mechanisms to interventions – Cell

 

Commentary on Twitter

Under a CC BY-NC-ND 4.0 license

 

WHO reveals shocking extent of exploitative formula milk marketing.

29 Apr, 2022 | 10:58h | UTC

News Release: WHO reveals shocking extent of exploitative formula milk marketing – World Health Organization

Report: Scope and impact of digital marketing strategies for promoting breastmilk substitutes – World Health Organization

Related: More than half of parents and pregnant women exposed to aggressive formula milk marketing – WHO, UNICEF – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

Review: Understanding vaccine safety and the roles of the FDA and the CDC.

29 Apr, 2022 | 11:13h | UTC

Understanding Vaccine Safety and the Roles of the FDA and the CDC – New England Journal of Medicine

 

Commentary on Twitter

 

RCT: BCG vaccine is not effective in reducing healthcare worker absenteeism in COVID-19 pandemic.

29 Apr, 2022 | 11:05h | UTC

BCG vaccine to reduce healthcare worker absenteeism in COVID-19 pandemic, a randomized controlled trial – Clinical Microbiology and Infection

 

Commentary on Twitter

 

Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.

29 Apr, 2022 | 11:07h | UTC

Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit – The Conversation

Related:

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

The Lancet Series: Optimizing child and adolescent health and development.

29 Apr, 2022 | 10:55h | UTC

Homepage: Optimising Child and Adolescent Health and Development – The Lancet (free registration required for all articles)

Health and development from preconception to 20 years of age and human capital

Effects of early-life poverty on health and human capital in children and adolescents: analyses of national surveys and birth cohort studies in LMICs

What can work and how? An overview of evidence-based interventions and delivery strategies to support health and human development from before conception to 20 years

Improving health and social systems for all children in LMICs: structural innovations to deliver high-quality services

Optimising child and adolescent health and development in the post-pandemic world

Opportunities in crisis for optimising child health and development

 

Review: The gut microbiome as a modulator of healthy ageing.

29 Apr, 2022 | 10:47h | UTC

The gut microbiome as a modulator of healthy ageing – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one via PMC)

 

Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.

29 Apr, 2022 | 10:51h | UTC

Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them – Antimicrobial Stewardship & Healthcare Epidemiology

 

Commentary on Twitter

Under a http://creativecommons.org/licenses/by/4.0/ license

 

M-A: Household secondary attack rates of SARS-CoV-2 by variant and vaccination status.

29 Apr, 2022 | 10:57h | UTC

Household Secondary Attack Rates of SARS-CoV-2 by Variant and Vaccination Status: An Updated Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 

M-A: Coronary flow reserve and cardiovascular outcomes.

29 Apr, 2022 | 10:43h | UTC

Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis – European Heart Journal

 

Commentary on Twitter

 

Varicose veins: what can be done to help?

29 Apr, 2022 | 10:49h | UTC

Varicose veins: what can be done to help? – Evidently Cochrane

Related:

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration – Cochrane Library

Interventions for great saphenous vein incompetence – Cochrane Library

Surgery for deep venous insufficiency – Cochrane Library

CHIVA method for the treatment of chronic venous insufficiency – Cochrane Library

Injection sclerotherapy for varicose veins – Cochrane Library

 

Expert Consensus: Topical treatment of recurrent vulvovaginal candidiasis.

29 Apr, 2022 | 10:46h | UTC

Topical Treatment of Recurrent Vulvovaginal Candidiasis: An Expert Consensus – Women’s Health Reports

 

Systematic Review: Antiepileptic drugs for the primary and secondary prevention of seizures after stroke.

29 Apr, 2022 | 10:45h | UTC

Antiepileptic drugs for the primary and secondary prevention of seizures after stroke – Cochrane Library

Summary: Effects of antiepileptic drugs for the primary and secondary prevention of seizures after stroke – Cochrane Library

 

M-A: Dietary fiber in hypertension and cardiovascular disease management.

29 Apr, 2022 | 08:26h | UTC

Dietary fibre in hypertension and cardiovascular disease management: systematic review and meta-analyses – BMC Medicine

 

Perspective | Obesity – an unexplained epidemic.

29 Apr, 2022 | 08:23h | UTC

Obesity – an unexplained epidemic – American Journal of Clinical Nutrition

 

Commentary on Twitter

 

Review: Perioperative nutritional support.

29 Apr, 2022 | 08:25h | UTC

Perioperative Nutritional Support: A Review of Current Literature – Nutrients

 

Study Commentary | People of all ages benefit from drugs to lower blood pressure.

29 Apr, 2022 | 08:18h | UTC

People of all ages benefit from drugs to lower blood pressure – National Institute for Health and Care Research

Original Study: Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis – The Lancet

 

Study Commentary | Mesh surgery for prolapse: complications are uncommon.

29 Apr, 2022 | 08:19h | UTC

Mesh surgery for prolapse: complications are uncommon – National Institute for Health and Care Research

Original Study: How common are complications following polypropylene mesh, biological xenograft and native tissue surgery for pelvic organ prolapse? A secondary analysis from the PROSPECT trial – BJOG

 

RCT: Effect of an interdisciplinary weight loss and lifestyle intervention on obstructive sleep apnea severity.

29 Apr, 2022 | 08:14h | UTC

Effect of an Interdisciplinary Weight Loss and Lifestyle Intervention on Obstructive Sleep Apnea Severity: The INTERAPNEA Randomized Clinical Trial – JAMA Network Open

Commentary: Weight Loss, Lifestyle Interventions Improve Obstructive Sleep Apnea – HCP Live

 

Commentary on Twitter

 

Tracing the emergence of drowning prevention on the global health and development agenda: a policy analysis.

29 Apr, 2022 | 08:16h | UTC

Tracing the emergence of drowning prevention on the global health and development agenda: a policy analysis – The Lancet Global Health

Related:

WHO Guideline on the prevention of drowning through provision of day-care and basic swimming and water safety skills – World health Organization

Wilderness Medical Society Clinical Practice Guidelines for the Treatment and Prevention of Drowning: 2019 Update

Prevention of Drowning – Pediatrics

The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study – Injury Prevention

Preventing drowning: an implementation guide – World Health Organization

Global report on drowning: preventing a leading killer – World Health Organization

Hidden Hazards: An Exploration of Open Water Drowning and Risks for Children – Safe Kids Worldwide

 

Commentary on Twitter

 

Evidence-based approach to the treatment of esophagogastric junction tumors.

29 Apr, 2022 | 08:12h | UTC

Evidence-based approach to the treatment of esophagogastric junction tumors – World Journal of Clinical Oncology

 

Guidelines for discontinuation of antipsychotics in patients who recover from first-episode schizophrenia spectrum disorders.

29 Apr, 2022 | 08:10h | UTC

Guidelines for discontinuation of antipsychotics in patients who recover from first-episode schizophrenia spectrum disorders: derived from the aggregated opinions of Asian network of early psychosis experts and literature review – International Journal of Neuropsychopharmacology

 

Systematic Review: Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia.

29 Apr, 2022 | 11:09h | UTC

Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia – Cochrane Library

Summary: How accurate are remote, virtual assessments at diagnosing dementia? – Cochrane Library

 

Cohort Study: Neurocognitive development in children at familial high risk of schizophrenia or bipolar disorder.

29 Apr, 2022 | 08:07h | UTC

Neurocognitive Development in Children at Familial High Risk of Schizophrenia or Bipolar Disorder – JAMA Psychiatry (link to abstract – $ for full-text)

Commentary: Children at Risk for Schizophrenia Show Early Neurocognitive Deficits – Psychiatric News Alert

 

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