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Daily Archives: March 22, 2022

ANN Guideline: Stroke prevention in symptomatic large artery intracranial atherosclerosis practice advisory.

22 Mar, 2022 | 09:51h | UTC

Stroke Prevention in Symptomatic Large Artery Intracranial Atherosclerosis Practice Advisory: Report of the AAN Guideline Subcommittee – Neurology

News Release: AAN issues guidance on preventing second stroke in those with plaque in brain arteries – American Academy of Neurology

 


New WHO guidelines on the management of tuberculosis in children and adolescents.

22 Mar, 2022 | 09:52h | UTC

WHO consolidated guidelines on tuberculosis Module 5: Management of tuberculosis in children and adolescents – World Health Organization

Commentary: New Children’s TB Guidelines a ‘Game-Changer’ With Non-Invasive Tests, Shortened Treatments – Health Policy Watch

Related: RCT: In children with nonsevere, drug-susceptible tuberculosis, treatment for 4 months is noninferior to treatment for 6 months.

 


AHA Scientific Statement: Understanding the importance of the lay responder experience in out-of-hospital cardiac arrest.

22 Mar, 2022 | 09:49h | UTC

Understanding the Importance of the Lay Responder Experience in Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association – Circulation

News Release: Lay rescuers who do CPR are heroes and survivors, new statement addresses their perspective – American Heart Association

Commentary: AHA News: CPR ‘Heroes’ Need More Support, Report Says – HealthDay

Related study: Pre-post study: The introduction of a text-message alert system to alert volunteers close to a cardiac arrest patient at home was associated with increased survival to hospital discharge.

 


Review: When to operate after SARS-CoV-2 infection?

22 Mar, 2022 | 09:44h | UTC

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Related:

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 


Study shows whole-genome risk prediction of common diseases in human preimplantation embryos is feasible, leading to ethical concerns.

22 Mar, 2022 | 09:42h | UTC

Whole-genome risk prediction of common diseases in human preimplantation embryos – Nature Medicine

Invited Commentaries:

Polygenic embryo testing: understated ethics, unclear utility – Nature Medicine

The uncertain science of preimplantation and prenatal genetic testing – Nature Medicine

Commentary: As genetic testing of human embryos expand, researchers call for frank assessment of profound ethical implications – The Hastings Center

Related: Opinion | “The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice”.

 

Commentary on Twitter (thread – click for more)

 


RCT: Effect of a physical activity and behavior maintenance program on functional mobility decline in older adults.

22 Mar, 2022 | 09:47h | UTC

Effect of a physical activity and behaviour maintenance programme on functional mobility decline in older adults: the REACT (Retirement in Action) randomised controlled trial – The Lancet Public Health

See also: Cost-effectiveness of a physical activity and behaviour maintenance programme on functional mobility decline in older adults: an economic evaluation of the REACT (Retirement in Action) trial – The Lancet Public Health

News Release: Landmark study demonstrates long-term positive impacts and cost effectiveness of tailored group exercise for over-65s with mobility limitations

Invited Commentary: Considerations for maintaining functional mobility in older populations – The Lancet Public Health

 


Preventing and treating the common cold: what’s the evidence?

22 Mar, 2022 | 08:56h | UTC

Preventing and treating the common cold: what’s the evidence? – Evidently Cochrane

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1505978560078659587

 


Perspective | Teaching more about less: preparing clinicians for practice.

22 Mar, 2022 | 08:51h | UTC

Teaching More About Less: Preparing Clinicians for Practice – The American Journal of Medicine (free for a limited period)

 


Viewpoint: Preparing clinicians for a clinical world influenced by artificial intelligence.

22 Mar, 2022 | 08:49h | UTC

Preparing Clinicians for a Clinical World Influenced by Artificial Intelligence – JAMA (free for a limited period)

 


Study shows low risk of acute myocardial infarction after ophthalmologic procedures, confirming previous knowledge that preoperative evaluation may be unnecessary for most patients.

22 Mar, 2022 | 08:47h | UTC

Risk for Acute Myocardial Infarction After Ophthalmologic Procedures – Annals of Internal Medicine (link to abstract – $ for full-text)

Summary for patients: Summary for Patients: Risk for Heart Attack After Eye Procedures

Editorial: Preoperative Evaluation Can Delay Ophthalmologic Surgery Without Improving Outcomes ($)

Commentary: Ophthalmologic Procedures Not Tied to Increased AMI Risk – HealthDay

Related:

Position Statement: Preoperative Care for Cataract Surgery – “In spite of evidence debunking the utility of testing before cataract surgery, studies suggest that medical testing and the use of medical consultations before cataract surgery continue to increase”.

Study: Prevalence and Cost of Care Cascades After Low-Value Preoperative Electrocardiogram for Cataract Surgery

Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery

Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery

Preoperative Medical Testing in Medicare Patients Undergoing Cataract Surgery – New England Journal of Medicine

 

Commentary on Twitter

 


Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents.

22 Mar, 2022 | 08:34h | UTC

Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular guidelines project: Associação Médica Brasileira – 2022 – Hematology, Transfusion and Cell Therapy

Related: RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

 


Consensus Paper: Vitamin D and calcium intakes in general pediatric populations.

22 Mar, 2022 | 08:36h | UTC

Vitamin D and calcium intakes in general pediatric populations: A French expert consensus paper – Archives de Pédiatrie

 


Guideline Synopsis: The management of substance use disorders.

22 Mar, 2022 | 08:38h | UTC

The Management of Substance Use Disorders: Synopsis of the 2021 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline – Annals of Internal Medicine

 


Long-term longitudinal patterns of patient-reported fatigue after breast cancer: a group-based trajectory analysis.

22 Mar, 2022 | 08:29h | UTC

Long-Term Longitudinal Patterns of Patient-Reported Fatigue After Breast Cancer: A Group-Based Trajectory Analysis – Journal of Clinical Oncology

 

Commentary on Twitter

https://twitter.com/PTarantinoMD/status/1503916087829794816

 


Evaluation of glial and neuronal blood biomarkers compared with clinical decision rules in assessing the need for computed tomography in patients with mild traumatic brain injury.

22 Mar, 2022 | 08:33h | UTC

Evaluation of Glial and Neuronal Blood Biomarkers Compared With Clinical Decision Rules in Assessing the Need for Computed Tomography in Patients With Mild Traumatic Brain Injury – JAMA Network Open

 

Commentary on Twitter

 


Editorial: Pig-to-human transplants take a leap toward reality.

22 Mar, 2022 | 08:31h | UTC

Pig-to-human transplants take a leap toward reality – Nature Medicine

 


RCT: Levothyroxine is not beneficial for euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss.

22 Mar, 2022 | 08:24h | UTC

Levothyroxine in euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss (T4LIFE trial): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentary: Levothyroxine No Boon for Birth Rates in Women With Possible Thyroid Disorder – MedPage Today (free registration required)

 


Enabling patient choice: the “deciding not to decide” option for older adults facing dialysis decisions.

22 Mar, 2022 | 08:25h | UTC

Enabling Patient Choice: The “Deciding Not to Decide” Option for Older Adults Facing Dialysis Decisions – Journal of the American Society of Nephrology

Commentary: The “Deciding Not to Decide” Option Can Improve Older Adult Patient Care – Rutgers University-New Brunswick

 


Phase 2 trial of Iberdomide in systemic lupus erythematosus.

22 Mar, 2022 | 08:27h | UTC

Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Mixed Results for Oral Lupus Drug in Phase II— Mid-stage study offers hope but also reason for caution – MedPage Today (free registration required)

 

Commentary on Twitter

 


Daytime napping and Alzheimer’s dementia: A potential bidirectional relationship.

22 Mar, 2022 | 08:14h | UTC

Daytime napping and Alzheimer’s dementia: A potential bidirectional relationship – Alzheimer’s & Dementia

Commentaries:

Researchers find a ‘vicious cycle’ between excessive daytime napping and Alzheimer’s dementia – Brigham and Women’s Hospital

Long naps may be early sign of Alzheimer’s disease, study shows – The Guardian

Excessive daytime naps may be a sign of early cognitive decline – MedicalResearch

 


Outcomes and safety of history-based screening for medication abortion: a retrospective multicenter cohort study.

22 Mar, 2022 | 08:11h | UTC

Outcomes and Safety of History-Based Screening for Medication Abortion: A Retrospective Multicenter Cohort Study – JAMA Internal Medicine

Invited Commentary: It Is Time to Change the Standard of Medication Abortion – JAMA Internal Medicine (free for a limited period)

 


RCT: Safety and efficacy of AGN-190584 in individuals with presbyopia.

22 Mar, 2022 | 08:20h | UTC

Safety and Efficacy of AGN-190584 in Individuals With Presbyopia: The GEMINI 1 Phase 3 Randomized Clinical Trial – JAMA Ophthalmology

 

Commentary on Twitter

 


Investigating cognition in midlife.

22 Mar, 2022 | 08:13h | UTC

Investigating cognition in midlife – Alzheimer’s & Dementia

 


Current management of urachal carcinoma: an evidence-based guide for clinical practice.

22 Mar, 2022 | 08:09h | UTC

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice – European Urology Open Science

 


Evidence-based disposition of acute pancreatitis.

22 Mar, 2022 | 08:08h | UTC

Evidence-Based Disposition of Acute Pancreatitis – emDocs

Related Guidelines:

2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

Pancreatitis – National Institute for Health and Care Excellence

 


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