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Daily Archives: March 22, 2022

ANN Guideline: Stroke prevention in symptomatic large artery intracranial atherosclerosis practice advisory.

22 Mar, 2022 | 09:51h | UTC

Stroke Prevention in Symptomatic Large Artery Intracranial Atherosclerosis Practice Advisory: Report of the AAN Guideline Subcommittee – Neurology

News Release: AAN issues guidance on preventing second stroke in those with plaque in brain arteries – American Academy of Neurology

 


New WHO guidelines on the management of tuberculosis in children and adolescents.

22 Mar, 2022 | 09:52h | UTC

WHO consolidated guidelines on tuberculosis Module 5: Management of tuberculosis in children and adolescents – World Health Organization

Commentary: New Children’s TB Guidelines a ‘Game-Changer’ With Non-Invasive Tests, Shortened Treatments – Health Policy Watch

Related: RCT: In children with nonsevere, drug-susceptible tuberculosis, treatment for 4 months is noninferior to treatment for 6 months.

 


AHA Scientific Statement: Understanding the importance of the lay responder experience in out-of-hospital cardiac arrest.

22 Mar, 2022 | 09:49h | UTC

Understanding the Importance of the Lay Responder Experience in Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association – Circulation

News Release: Lay rescuers who do CPR are heroes and survivors, new statement addresses their perspective – American Heart Association

Commentary: AHA News: CPR ‘Heroes’ Need More Support, Report Says – HealthDay

Related study: Pre-post study: The introduction of a text-message alert system to alert volunteers close to a cardiac arrest patient at home was associated with increased survival to hospital discharge.

 


Review: When to operate after SARS-CoV-2 infection?

22 Mar, 2022 | 09:44h | UTC

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Related:

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 


Study shows whole-genome risk prediction of common diseases in human preimplantation embryos is feasible, leading to ethical concerns.

22 Mar, 2022 | 09:42h | UTC

Whole-genome risk prediction of common diseases in human preimplantation embryos – Nature Medicine

Invited Commentaries:

Polygenic embryo testing: understated ethics, unclear utility – Nature Medicine

The uncertain science of preimplantation and prenatal genetic testing – Nature Medicine

Commentary: As genetic testing of human embryos expand, researchers call for frank assessment of profound ethical implications – The Hastings Center

Related: Opinion | “The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice”.

 

Commentary on Twitter (thread – click for more)

 


RCT: Effect of a physical activity and behavior maintenance program on functional mobility decline in older adults.

22 Mar, 2022 | 09:47h | UTC

Effect of a physical activity and behaviour maintenance programme on functional mobility decline in older adults: the REACT (Retirement in Action) randomised controlled trial – The Lancet Public Health

See also: Cost-effectiveness of a physical activity and behaviour maintenance programme on functional mobility decline in older adults: an economic evaluation of the REACT (Retirement in Action) trial – The Lancet Public Health

News Release: Landmark study demonstrates long-term positive impacts and cost effectiveness of tailored group exercise for over-65s with mobility limitations

Invited Commentary: Considerations for maintaining functional mobility in older populations – The Lancet Public Health

 


Preventing and treating the common cold: what’s the evidence?

22 Mar, 2022 | 08:56h | UTC

Preventing and treating the common cold: what’s the evidence? – Evidently Cochrane

 

Commentary on Twitter

 


Perspective | Teaching more about less: preparing clinicians for practice.

22 Mar, 2022 | 08:51h | UTC

Teaching More About Less: Preparing Clinicians for Practice – The American Journal of Medicine (free for a limited period)

 


Viewpoint: Preparing clinicians for a clinical world influenced by artificial intelligence.

22 Mar, 2022 | 08:49h | UTC

Preparing Clinicians for a Clinical World Influenced by Artificial Intelligence – JAMA (free for a limited period)

 


Study shows low risk of acute myocardial infarction after ophthalmologic procedures, confirming previous knowledge that preoperative evaluation may be unnecessary for most patients.

22 Mar, 2022 | 08:47h | UTC

Risk for Acute Myocardial Infarction After Ophthalmologic Procedures – Annals of Internal Medicine (link to abstract – $ for full-text)

Summary for patients: Summary for Patients: Risk for Heart Attack After Eye Procedures

Editorial: Preoperative Evaluation Can Delay Ophthalmologic Surgery Without Improving Outcomes ($)

Commentary: Ophthalmologic Procedures Not Tied to Increased AMI Risk – HealthDay

Related:

Position Statement: Preoperative Care for Cataract Surgery – “In spite of evidence debunking the utility of testing before cataract surgery, studies suggest that medical testing and the use of medical consultations before cataract surgery continue to increase”.

Study: Prevalence and Cost of Care Cascades After Low-Value Preoperative Electrocardiogram for Cataract Surgery

Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery

Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery

Preoperative Medical Testing in Medicare Patients Undergoing Cataract Surgery – New England Journal of Medicine

 

Commentary on Twitter

 


Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents.

22 Mar, 2022 | 08:34h | UTC

Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular guidelines project: Associação Médica Brasileira – 2022 – Hematology, Transfusion and Cell Therapy

Related: RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

 


Consensus Paper: Vitamin D and calcium intakes in general pediatric populations.

22 Mar, 2022 | 08:36h | UTC

Vitamin D and calcium intakes in general pediatric populations: A French expert consensus paper – Archives de Pédiatrie

 


Guideline Synopsis: The management of substance use disorders.

22 Mar, 2022 | 08:38h | UTC

The Management of Substance Use Disorders: Synopsis of the 2021 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline – Annals of Internal Medicine

 


Long-term longitudinal patterns of patient-reported fatigue after breast cancer: a group-based trajectory analysis.

22 Mar, 2022 | 08:29h | UTC

Long-Term Longitudinal Patterns of Patient-Reported Fatigue After Breast Cancer: A Group-Based Trajectory Analysis – Journal of Clinical Oncology

 

Commentary on Twitter

 


Evaluation of glial and neuronal blood biomarkers compared with clinical decision rules in assessing the need for computed tomography in patients with mild traumatic brain injury.

22 Mar, 2022 | 08:33h | UTC

Evaluation of Glial and Neuronal Blood Biomarkers Compared With Clinical Decision Rules in Assessing the Need for Computed Tomography in Patients With Mild Traumatic Brain Injury – JAMA Network Open

 

Commentary on Twitter

 


Editorial: Pig-to-human transplants take a leap toward reality.

22 Mar, 2022 | 08:31h | UTC

Pig-to-human transplants take a leap toward reality – Nature Medicine

 


RCT: Levothyroxine is not beneficial for euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss.

22 Mar, 2022 | 08:24h | UTC

Levothyroxine in euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss (T4LIFE trial): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentary: Levothyroxine No Boon for Birth Rates in Women With Possible Thyroid Disorder – MedPage Today (free registration required)

 


Enabling patient choice: the “deciding not to decide” option for older adults facing dialysis decisions.

22 Mar, 2022 | 08:25h | UTC

Enabling Patient Choice: The “Deciding Not to Decide” Option for Older Adults Facing Dialysis Decisions – Journal of the American Society of Nephrology

Commentary: The “Deciding Not to Decide” Option Can Improve Older Adult Patient Care – Rutgers University-New Brunswick

 


Phase 2 trial of Iberdomide in systemic lupus erythematosus.

22 Mar, 2022 | 08:27h | UTC

Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Mixed Results for Oral Lupus Drug in Phase II— Mid-stage study offers hope but also reason for caution – MedPage Today (free registration required)

 

Commentary on Twitter

 


Daytime napping and Alzheimer’s dementia: A potential bidirectional relationship.

22 Mar, 2022 | 08:14h | UTC

Daytime napping and Alzheimer’s dementia: A potential bidirectional relationship – Alzheimer’s & Dementia

Commentaries:

Researchers find a ‘vicious cycle’ between excessive daytime napping and Alzheimer’s dementia – Brigham and Women’s Hospital

Long naps may be early sign of Alzheimer’s disease, study shows – The Guardian

Excessive daytime naps may be a sign of early cognitive decline – MedicalResearch

 


Outcomes and safety of history-based screening for medication abortion: a retrospective multicenter cohort study.

22 Mar, 2022 | 08:11h | UTC

Outcomes and Safety of History-Based Screening for Medication Abortion: A Retrospective Multicenter Cohort Study – JAMA Internal Medicine

Invited Commentary: It Is Time to Change the Standard of Medication Abortion – JAMA Internal Medicine (free for a limited period)

 


RCT: Safety and efficacy of AGN-190584 in individuals with presbyopia.

22 Mar, 2022 | 08:20h | UTC

Safety and Efficacy of AGN-190584 in Individuals With Presbyopia: The GEMINI 1 Phase 3 Randomized Clinical Trial – JAMA Ophthalmology

 

Commentary on Twitter

 


Investigating cognition in midlife.

22 Mar, 2022 | 08:13h | UTC

Investigating cognition in midlife – Alzheimer’s & Dementia

 


Current management of urachal carcinoma: an evidence-based guide for clinical practice.

22 Mar, 2022 | 08:09h | UTC

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice – European Urology Open Science

 


Evidence-based disposition of acute pancreatitis.

22 Mar, 2022 | 08:08h | UTC

Evidence-Based Disposition of Acute Pancreatitis – emDocs

Related Guidelines:

2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

Pancreatitis – National Institute for Health and Care Excellence

 


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