Daily Archives: March 9, 2022 | LinksMedicus Free Medical News & Perspectives

NEW research—resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care: results of #RePHILL, a randomised, controlled, phase 3 trial #openaccess #EmergencyMedicine ??https://t.co/Ci0lMMCryX pic.twitter.com/iWEtV12N1r

— The Lancet Haematology (@TheLancetHaem) March 8, 2022

Cohort Study: One-year trajectory of cognitive changes in older survivors of COVID-19 in Wuhan, China.

9 Mar, 2022 | 09:51h | UTC

One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China: A Longitudinal Cohort Study – JAMA Neurology

WHO says COVID boosters needed, reversing previous call.

9 Mar, 2022 | 09:49h | UTC

WHO says COVID boosters needed, reversing previous call – Associated Press

Commentary on Twitter

Who needs a booster? The @WHO reverses its position and supports "urgent and broad" 3-shot vaccination https://t.co/y5pyY9bJr7 @AP The evidence has supported that move for several months.
"Fully vaccinated" = 3-shots
(or confirmed infection-acquired immunity + 1 shot)

— Eric Topol (@EricTopol) March 8, 2022

IDSA Guidance on the treatment of antimicrobial-resistant Gram-Negative infections – A focus on extended-spectrum β-lactamase producing Enterobacterales, Carbapenem-resistant Enterobacterales, and Pseudomonas aeruginosa with difficult-to-treat resistance.

9 Mar, 2022 | 08:51h | UTC

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections: Version 1.0 – Infectious Diseases Society of America

Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa – Infectious Diseases and Therapy

IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections – Clinical Microbiology and Infection

European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

Safety of mRNA vaccines administered during the initial 6 months of the US COVID-19 vaccination program.

9 Mar, 2022 | 09:46h | UTC

Safety of mRNA vaccines administered during the initial 6 months of the US COVID-19 vaccination programme: an observational study of reports to the Vaccine Adverse Event Reporting System and v-safe – The Lancet Infectious Diseases

Commentaries:

Large US study confirms most mRNA COVID-19 vaccine side effects are mild and temporary – Lancet

Covid vaccines not linked to deaths, major US study finds – BBC

Most mRNA COVID vaccine adverse events mild, transient – CIDRAP

Guideline for perioperative care for people living with frailty undergoing elective and emergency surgery.

9 Mar, 2022 | 08:48h | UTC

Guideline for Perioperative Care for People Living with Frailty Undergoing Elective and Emergency Surgery – British Geriatric Society

SARS-CoV-2 is associated with changes in brain structure in UK Biobank.

9 Mar, 2022 | 09:53h | UTC

SARS-CoV-2 is associated with changes in brain structure in UK Biobank – Nature

Commentary:

Brain changes after COVID revealed by imaging – Nature

Even mild cases of COVID-19 can leave a mark on the brain, such as reductions in gray matter – a neuroscientist explains emerging research – The Conversation

Scans reveal how Covid may change the brain – BBC

Position Paper: Mental health-related risk factors and interventions in patients with heart failure.

9 Mar, 2022 | 08:49h | UTC

Mental health-related risk factors and interventions in patients with heart failure: a position paper endorsed by the European Association of Preventive Cardiology (EAPC) – European Journal of Preventive Cardiology

Commentary on Twitter

?#EAPC_ESC Position paper in #EJPC #MentalHealth & #HeartFailure – overview of the scientific evidence of #psychosocial aspects of #HF https://t.co/5Xr6500zWW #MentalHealthMatters #MentalHealthAwareness @frank_doyle4 @ma_hamer @HendrikSager @m_piepoli @SilCastelletti pic.twitter.com/DQyAob9y4s

— European Society of Cardiology Journals (@ESC_Journals) February 20, 2022

Recent updates to clinical practice guidelines for diabetes mellitus.

9 Mar, 2022 | 08:46h | UTC

Recent Updates to Clinical Practice Guidelines for Diabetes Mellitus – Endocrinology and Metabolism

Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices.

9 Mar, 2022 | 08:45h | UTC

Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices – BMJ Open

Association of acute respiratory failure in early childhood with long-term neurocognitive outcomes.

9 Mar, 2022 | 08:41h | UTC

Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes – JAMA (link to abstract – $ for full-text)

Commentaries:

IQ Lower for Survivors of PICU Respiratory Failure Hospitalization – HealthDay

Investigating The Effects of Critical Illness in Early Childhood On Neurocognitive Outcomes – University of Pennsylvania School of Nursing

RCT: Combination treatment with Varenicline and Nicotine patch may increase smoking cessation rates among smokers who drink heavily.

9 Mar, 2022 | 08:44h | UTC

Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily: A Randomized Clinical Trial – JAMA Network Open

Commentary: Combination treatment is effective for treating smokers who drink heavily – University of Chicago Medical Center

Commentary on Twitter

In this RCT, the combination of varenicline + nicotine patch was superior to placebo + nicotine patch in increasing smoking quit rates in smokers who drink heavily. https://t.co/UbekBdEjyA

— JAMA Network Open (@JAMANetworkOpen) March 4, 2022

M-A: Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia.

9 Mar, 2022 | 08:38h | UTC

Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentary on Twitter

New—Association between #maternal #thyroid function and risk of #gestational #hypertension and #pre-eclampsia: a systematic review and individual-participant data meta-analysis https://t.co/tlsDzX5C77 #thyroid #hypothyroidism #levothyroxine pic.twitter.com/aLu2ZgmWKl

— The Lancet Diabetes & Endocrinology (@TheLancetEndo) March 4, 2022

RCT: S-1 plus Oxaliplatin is non-inferior to Fluorouracil, Leucovorin plus Oxaliplatin as perioperative chemotherapy for locally advanced, resectable gastric cancer.

9 Mar, 2022 | 08:43h | UTC

Effect of S-1 Plus Oxaliplatin Compared With Fluorouracil, Leucovorin Plus Oxaliplatin as Perioperative Chemotherapy for Locally Advanced, Resectable Gastric Cancer: A Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

In this RCT, S-1 plus oxaliplatin was noninferior to fluorouracil, leucovorin plus oxaliplatin as perioperative chemotherapy regimen for patients with locally advanced gastric cancer. https://t.co/W6fc1YcSBd

— JAMA Network Open (@JAMANetworkOpen) February 28, 2022