Daily Archives: March 8, 2022 | LinksMedicus Free Medical News & Perspectives

RCT: Azithromycin is not effective for the prevention of recurrent wheeze following severe respiratory syncytial virus bronchiolitis.

8 Mar, 2022 | 08:49h | UTC

Azithromycin to Prevent Recurrent Wheeze Following Severe Respiratory Syncytial Virus Bronchiolitis – NEJM Evidence

Commentaries:

Study finds azithromycin use during RSV not useful in preventing recurrent wheezing, may cause harm – Vanderbilt University Medical Center

Antibiotic doesn’t prevent future wheezing in babies hospitalized with RSV – Washington University in St. Louis

Commentary on Twitter

This RCT tested oral azithromycin vs placebo to reduce recurrent wheeze (RW) in 1-18-month-olds hospitalized with acute severe RSV bronchiolitis. Azithromycin did not reduce occurrence of RW and may increase risk of RW in some groups. #AAAAI22 #Asthma #EBM https://t.co/jYcBuiQ8aY pic.twitter.com/u65NbQaIlX

— NEJM Evidence (@NEJMEvidence) February 28, 2022

AHA Scientific Statement: Cardio-oncology drug interactions.

8 Mar, 2022 | 09:53h | UTC

Cardio-Oncology Drug Interactions: A Scientific Statement From the American Heart Association – Circulation

Doing more can be worse: ten common errors in the ICU.

8 Mar, 2022 | 08:51h | UTC

Doing More Can Be Worse: Ten Common Errors in the ICU – ICU Management & Practice

How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain.

8 Mar, 2022 | 08:56h | UTC

How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain – The Conversation

Study shows the number of covid-19 infections missed by lateral flow tests “substantial enough to be of clinical importance”.

8 Mar, 2022 | 08:57h | UTC

News Release: Number of covid-19 infections missed by lateral flow tests “substantial enough to be of clinical importance,” warn experts – BMJ

Original Study: SARS-CoV-2 antigen lateral flow tests for detecting infectious people: linked data analysis – The BMJ

Commentaries:

Lateral flow tests may be missing ‘substantial’ number of COVID-19 infections – Imperial College London

Self-testing for asymptomatic non-contacts using rapid antigen tests—is this leading to a cost effective reduction in infection transmission? – The BMJ

RCT: Screening for atrial fibrillation in older adults using a single-lead ECG did not increase detection rates at one year.

8 Mar, 2022 | 09:51h | UTC

Screening for Atrial Fibrillation in Older Adults at Primary Care Visits: the VITAL-AF Randomized Controlled Trial – Circulation (link to abstract – $ for full-text)

USPSTF Recommendation Statement: Still not enough evidence to recommend atrial fibrillation screening.

#ESCCongress – RCT: In individuals at risk for stroke, screening for atrial fibrillation using loop recorder resulted in a three-times increase in atrial fibrillation detection and anticoagulation initiation but did not reduce the risk of stroke or systemic arterial embolism.

#ESCCongress – RCT: Small benefit from systematic screening for atrial fibrillation in older adults – After a median follow-up of 6.9 y there were fewer events (stroke, embolism, bleeding, and death) in the intervention group (31·9%) vs. control group (33·0%).

Clinical Review: Screening and management of atrial fibrillation in primary care

[News release – not published yet] New Sanofi and GSK vaccine demonstrates strong protection against severe Covid-19 in clinical trials.

8 Mar, 2022 | 08:53h | UTC

Commentary: New vaccine demonstrates strong protection against severe Covid-19 in clinical trials – CNN

News Release: Sanofi and GSK to seek regulatory authorization for COVID-19 vaccine

The next variant: three key questions about what’s after Omicron.

8 Mar, 2022 | 08:54h | UTC

The next variant: three key questions about what’s after Omicron – Nature

Nature is trialling transparent peer review — the early results are encouraging.

8 Mar, 2022 | 08:52h | UTC

Nature is trialling transparent peer review — the early results are encouraging – Nature

Guideline: Diagnosis and therapy of vitiligo.

8 Mar, 2022 | 08:46h | UTC

S1 Guideline: Diagnosis and therapy of vitiligo – Journal of the German Society of Dermatology

CDC, AAP update developmental milestones for surveillance program.

8 Mar, 2022 | 08:47h | UTC

News Release: CDC, AAP update developmental milestones for surveillance program – AAP News

See Guidance: Evidence-Informed Milestones for Developmental Surveillance Tools – Pediatrics

Commentaries:

Revised Developmental Milestone Guidelines For Infants And Toddlers: Explained Here – Forbes

Much Awaited – Development Milestone Checklists Updated by CDC & AAP – Pediatric OnCall

Guidelines on management of persons with multimorbidity and polypharmacy.

8 Mar, 2022 | 08:41h | UTC

Italian guidelines on management of persons with multimorbidity and polypharmacy – Aging Clinical and Experimental Research

Guideline for perioperative management of patients with inflammatory rheumatic diseases.

8 Mar, 2022 | 08:43h | UTC

Perioperative management of patients with inflammatory rheumatic diseases – Zeitschrift für Rheumatologie

Fighting against sudden cardiac death: need for a paradigm shift—Adding near-term prevention and pre-emptive action to long-term prevention.

8 Mar, 2022 | 08:39h | UTC

Fighting against sudden cardiac death: need for a paradigm shift—Adding near-term prevention and pre-emptive action to long-term prevention – European Heart Journal

Commentary on Twitter

Fighting against #SuddenCardiacDeath: need for a paradigm shift—Adding near-term prevention and pre-emptive action to long-term prevention https://t.co/5xLeUAB9QD @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/IGzZ8dmLd6

— European Society of Cardiology Journals (@ESC_Journals) March 7, 2022

Case report: Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices.

8 Mar, 2022 | 08:35h | UTC

Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices – Canadian Medical Association Journal

RCT: Little long-term benefit from a small change approach to prevent weight gain in adults with overweight and obesity.

8 Mar, 2022 | 08:37h | UTC

A small change approach to prevent long-term weight gain in adults with overweight and obesity: a randomized controlled trial – Canadian Medical Association Journal

RCT: Role of thoracic ultrasonography in pleurodesis pathways for malignant pleural effusions.

8 Mar, 2022 | 08:28h | UTC

Role of thoracic ultrasonography in pleurodesis pathways for malignant pleural effusions (SIMPLE): an open-label, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary on Twitter

Thoracic ultrasonography-guided pleurodesis in patients with malignant pleural effusions results in shorter hospital stay without reducing the success rate of the procedure at 3 monthshttps://t.co/hof4Rd2nUt

— K Pavithran (@drkpavithran) March 2, 2022