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Daily Archives: January 18, 2022

COVAX delivers one billionth COVID-19 vaccine dose – but 41% of world remains unvaccinated.

18 Jan, 2022 | 09:56h | UTC

COVAX Delivers One Billionth COVID-19 Vaccine Dose – But 41% of World Remains Unvaccinated – Health Policy Watch

See also: COVID program delivers 1 billion doses to poorer countries – Associated Press

Related:

Is Covax finally going to vaccinate the world?

How Covax failed on its promise to vaccinate the world – “Covax, described as “naively ambitious” by one expert, has contributed just 5% of all vaccines administered globally”.

Perspective | A beautiful idea: how COVAX has fallen short.

WHO Launches Strategy to Achieve Global Covid-19 Vaccination by mid-2022.

WHO special envoys: To beat Covid, there’s a simple lesson – no one’s safe until everyone’s safe.

Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO.

WHO COVAX Joint Statement: Call to action to equip COVAX to deliver 2 billion doses in 2021.

Covax: How will Covid vaccines be shared around the world?

 


Measures implemented in the school setting to contain the COVID‐19 pandemic: a rapid review.

18 Jan, 2022 | 09:54h | UTC

Measures implemented in the school setting to contain the COVID‐19 pandemic: a rapid review – Cochrane Library

News Release: Measures implemented in the school setting to contain the COVID-19 pandemic: a rapid review – Cochrane Library

 


[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

18 Jan, 2022 | 09:59h | UTC

Israel Finds Fourth COVID Booster is Ineffective, While Hospitalised Omicron Patients Fare Much Better Than Delta Patients – Health Policy Watch

See also:

Israeli trial, world’s first, finds 4th dose ‘not good enough’ against Omicron – The Times of Israel

Israel study: 4th vaccine shows limited results with omicron – MedicalXpress

 


COVID-19 updated evidence: a Cochrane round-up.

18 Jan, 2022 | 09:53h | UTC

COVID-19 evidence: a Cochrane round-up – Cochrane Library

 


Time to upgrade from cloth and surgical masks to respirators? Your questions answered.

18 Jan, 2022 | 09:48h | UTC

Time to upgrade from cloth and surgical masks to respirators? Your questions answered – The Conversation

See also: The CDC updated its mask guidelines. What to know about ‘the highest level of protection’ – CNN

Related: CDC urges Americans to wear most-protective mask or respirator that fits well and that they’ll wear consistently.

 


Study raises doubts about rapid Covid tests’ reliability in early days after infection.

18 Jan, 2022 | 09:51h | UTC

Study raises doubts about rapid Covid tests’ reliability in early days after infection – STAT

Original Article (preprint): Discordant SARS-CoV-2 PCR and Rapid Antigen Test Results When Infectious: A December 2021 Occupational Case Series – medRxiv

 


Review: Treatment of multisystem inflammatory syndrome (MIS-C) in children and adolescents.

18 Jan, 2022 | 09:46h | UTC

Treatment of MIS-C in Children and Adolescents – Current Pediatrics Reports

See also: Clinical practice guidelines in multisystem inflammatory syndrome (MIS-C) related to COVID-19: a critical review and recommendations – World Journal of Pediatrics

Related:

Review of 4,470 cases of Multisystem Inflammatory Syndrome in Children in the US.

WHO issues guidelines on the treatment of children with multisystem inflammatory syndrome associated with COVID-19.

An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.

Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

 


Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

18 Jan, 2022 | 09:41h | UTC

Case Series of Thrombosis With Thrombocytopenia Syndrome After COVID-19 Vaccination—United States, December 2020 to August 2021 – Annals of Internal Medicine

Editorial: The Epidemiology of Thrombosis With Thrombocytopenia Syndrome: Analogies With Heparin-Induced Thrombocytopenia – Annals of Internal Medicine

 


Shoulder injury related to SARS-CoV-2 vaccine administration.

18 Jan, 2022 | 09:40h | UTC

Shoulder injury related to SARS-CoV-2 vaccine administration – Canadian Medical Association Journal

 


Perspective | Post-acute neurological consequences of COVID-19: an unequal burden – “COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity”.

18 Jan, 2022 | 09:44h | UTC

Post-acute neurological consequences of COVID-19: an unequal burden – Nature Medicine

 


Pro-Con Debate: Cardiac Troponin measurement as part of routine follow-up of myocardial damage following noncardiac surgery.

18 Jan, 2022 | 09:36h | UTC

Pro-Con Debate: Cardiac Troponin Measurement as Part of Routine Follow-up of Myocardial Damage Following Noncardiac Surgery – Anesthesia & Analgesia

 


ACP Guideline: Diagnosis and management of acute left-sided colonic diverticulitis.

18 Jan, 2022 | 09:38h | UTC

Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Related Guideline: Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Related Systematic Reviews:

Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis: A Systematic Review – Annals of Internal Medicine

Evaluation and Management After Acute Left-Sided Colonic Diverticulitis: A Systematic Review – Annals of Internal Medicine

Annals Video Summary: Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis: A Systematic Review – Annals of Internal Medicine

News Release: ACP releases two new clinical guidelines on the diagnosis and management of diverticulitis – American College of Physicians

 


Study shows many patients with metastatic cancer near the end of life still receive guideline-nonconcordant radiotherapy.

18 Jan, 2022 | 09:35h | UTC

Assessment of Guideline-Nonconcordant Radiotherapy in Medicare Beneficiaries With Metastatic Cancer Near the End of Life, 2015-2017 – JAMA Health Forum

Commentary: Study: Cancer patients given high-dose radiation treatments even near end of life – UPI

 


Podcast: Lower Extremity Edema Pearls.

18 Jan, 2022 | 09:33h | UTC

#316 Lower Extremity Edema – The Curbsiders

 


Association of hormonal contraceptive use with adverse health outcomes: an umbrella review of meta-analyses of randomized clinical trials and cohort studies.

18 Jan, 2022 | 09:29h | UTC

Association of Hormonal Contraceptive Use With Adverse Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials and Cohort Studies – JAMA Network Open

 


Global, regional, and national burdens of hip osteoarthritis from 1990 to 2019: estimates from the 2019 Global Burden of Disease Study.

18 Jan, 2022 | 09:27h | UTC

Global, regional, and national burdens of hip osteoarthritis from 1990 to 2019: estimates from the 2019 Global Burden of Disease Study – Arthritis Research & Therapy

 


Review: Myocardial infarction with non-obstructive coronary artery disease.

18 Jan, 2022 | 09:24h | UTC

Myocardial infarction with non-obstructive coronary artery disease – EuroIntervention

Related:

MINOCA from A to Z – American College of Cardiology

Guidelines for the Management of Myocardial Infarction/injury with Non-obstructive Coronary Arteries (MINOCA)

Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries

Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association

The What, When, Who, Why, How and Where of Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA) – Circulation Journal

Systematic Review of Patients Presenting With Suspected Myocardial Infarction and Nonobstructive Coronary Arteries – Circulation

Nonobstructive Versus Obstructive Coronary Artery Disease in Acute Coronary Syndrome: A Meta‐Analysis – Journal of the American Heart Association

 


A national cohort study in Sweden showed pregnancy complications (preeclampsia or eclampsia, gestational hypertension, gestational diabetes, preterm birth, small for gestational age, and stillbirth) are associated with increased risk of cardiovascular disease later in life.

18 Jan, 2022 | 09:26h | UTC

Pregnancy Complications and Risk of Cardiovascular Disease Later in Life: A Nationwide Cohort Study – Journal of the American Heart Association

 


Cohort study: In patients who underwent bariatric surgery, those submitted to gastric bypass were slightly more likely to remain free of obesity-related medications during follow-up compared with those who underwent sleeve gastrectomy.

18 Jan, 2022 | 09:31h | UTC

Medication Use for Obesity-Related Comorbidities After Sleeve Gastrectomy or Gastric Bypass – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Gastric Bypass Tied to Modest Shift in Need for Comorbidity Meds – MedPage Today (free registration required)

 

Commentary on Twitter

 


Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide.

18 Jan, 2022 | 09:23h | UTC

Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide – American Journal of Clinical Dermatology

 


Cluster-randomized trial: Antiseptic bathing with 2% chlorhexidine-impregnated cloths and 0.08% octenidine wash mitts were not effective for preventing central-line associated bloodstream infections in intensive care patients.

18 Jan, 2022 | 09:18h | UTC

Effect of antiseptic bathing with chlorhexidine or octenidine on central-line associated bloodstream infections in intensive care patients: a cluster-randomised controlled trial – Clinical Microbiology and Infection

 


Review: Imaging of prostate cancer.

18 Jan, 2022 | 09:20h | UTC

Imaging of Prostate Cancer – Deutsches Ärzteblatt International

Related:

ASCO Guideline: Optimum Imaging Strategies for Advanced Prostate Cancer

RCT: MRI can cut overdiagnoses in prostate-cancer screening by half.

RCT: MRI-targeted biopsy safely reduces the need for biopsy in more than one-third of men at risk for prostate cancer

Meta-Analysis: Negative Predictive Value of MRI in the Detection of Clinically Significant Prostate Cancer

Study: MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis

Review: The Use of MRI and PET Imaging Studies for Prostate Cancer Management

Meta-Analysis: MRI plus Targeted Biopsy vs. Systematic Biopsy Alone for the Diagnosis of Prostate Cancer

Cochrane Review: MRI Pathway vs. Systematic Biopsy for Detecting Prostate Cancer

RCT: Inclusion of 18F-fluciclovine-PET/CT imaging to guide postprostatectomy salvage radiotherapy in patients with prostate cancer may improve survival free from biochemical recurrence or persistence.

Meta-analysis: Clinical Utility of MRI in the Decision-making Process Before Radical Prostatectomy

Research: Biparametric MRI (simpler, faster) May Be Used to Exclude Aggressive Disease and Avoid Unnecessary Biopsies in Men with Clinical Suspicion of Prostate Cancer

Research: MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis

Multiparametric MRI in the Detection of Clinically Significant Prostate Cancer

 


Meta-analysis of randomized controlled trials: Impact of intraoperative intravenous magnesium on spine surgery.

18 Jan, 2022 | 09:19h | UTC

Impact of intraoperative intravenous magnesium on spine surgery: A systematic review and meta-analysis of randomized controlled trials – EClinicalMedicine

 

Commentary on Twitter

 


Grand Challenges in global eye health: a global prioritization process using Delphi method.

18 Jan, 2022 | 09:15h | UTC

Grand Challenges in global eye health: a global prioritisation process using Delphi method – The Lancet Health Longevity

Related podcast: Author interview

 

Commentary on Twitter

 


Multicenter observational study: Reconstruction of paralyzed arm function in patients with hemiplegia through contralateral seventh cervical nerve cross transfer.

18 Jan, 2022 | 09:13h | UTC

Reconstruction of paralyzed arm function in patients with hemiplegia through contralateral seventh cervical nerve cross transfer: a multicenter study and real-world practice guidance – EClinicalMedicine

 


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