Daily Archives: January 11, 2022
Clinical Guideline: Acute-on-chronic liver failure.
11 Jan, 2022 | 02:43h | UTCAcute-on-Chronic Liver Failure Clinical Guidelines – American Journal of Gastroenterology
Related: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU
Commentary on Twitter
?NEW ACG Guidelines Acute-on-Chronic #Liver Failure by @JasmohanBajaj et al.
?https://t.co/T3CqvOAMrj#Cirrhosis #GItwitter #LiverTwitter #MostReadinRed pic.twitter.com/LHwIkUtGZt
— AJG – The American Journal of Gastroenterology (@AmJGastro) January 10, 2022
AHA Scientific Statement: Comprehensive management of cardiovascular risk factors for adults with Type 2 Diabetes.
11 Jan, 2022 | 02:40h | UTC
Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.
11 Jan, 2022 | 02:38h | UTCNews Release: Global dementia cases set to triple by 2050 unless countries address risk factors – The Lancet
Commentaries:
Forecasting the prevalence of dementia – The Lancet Public Health
Dementia cases expected to almost triple across the world by 2050 – BBC
Number of adults with dementia to exceed 150m by 2050, study finds – The Guardian
Commentary on Twitter (thread – click for more)
?✨First #GBDstudy forecasts global #dementia cases set to triple by 2050 (up from 57m in 2019 to expected 153m people) unless countries address risk factors: #smoking, #obesity, #HighBloodSugar, & low #education??
Published in @TheLancet @TheLancetPHhttps://t.co/GccTPRroEV
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) January 7, 2022
In 1st, US surgeons transplant pig heart into human patient.
11 Jan, 2022 | 02:34h | UTCIn 1st, US surgeons transplant pig heart into human patient – Associated Press
Position Statement: Prehospital surgical airway management.
11 Jan, 2022 | 02:39h | UTC
Special Issue: Peri‐operative and critical care management of the brain ‐ current evidence.
11 Jan, 2022 | 02:36h | UTCEditorials:
In search of the perfect outcome in neuroanaesthesia and neurocritical care
Anaesthesia and the older brain: what should we do?
Review Articles:
Implications of nocebo in anaesthesia care
Acute peri-operative neurocognitive disorders: a narrative review
Pragmatic sedation strategies to prevent secondary brain injury in low-resource settings
Delirium and COVID-19: a narrative review of emerging evidence
Anaesthesia for mechanical thrombectomy: a narrative review
Clinical applications of point-of-care ultrasound in brain injury: a narrative review
Management of status epilepticus: a narrative review
Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review
Management of traumatic brain injury: a narrative review of current evidence
Peri-operative management of patients with Parkinson’s disease
Medical Decisions: Some are Easy and Some Not So Much.
11 Jan, 2022 | 02:31h | UTCMedical Decisions: Some are Easy and Some Not So Much – Stop and Think blog, by John Mandrola
Commentary on Twitter
Preventive therapy reduces the probability of a negative outcome. There are 2 big snags with preventive therapy:
1. All medical interventions come with the potential for harm.
2. Preventive therapies have modest effect sizes.
great read by @drjohnm https://t.co/Hk8VPnUv3m— Tjasa Zajc (@zajctjasa) January 9, 2022
Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019.
11 Jan, 2022 | 02:30h | UTC
RCT: In premenopausal women with breast cancer, gonadotropin-releasing hormone analogs may preserve ovarian function against chemotherapy-induced gonadotoxic effects.
11 Jan, 2022 | 02:26h | UTCEffects of Gonadotropin-Releasing Hormone Analogs on Ovarian Function Against Chemotherapy-Induced Gonadotoxic Effects in Premenopausal Women With Breast Cancer in China: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Randomized clinical trial finds administration of gonadotropin-releasing hormone analogs (GnRHa) with chemotherapy in premenopausal pts with #BreastCancer reduces risk of premature ovarian insufficiency (#POI) and promotes recovery of ovarian function. https://t.co/gymbKT9GWZ pic.twitter.com/OUOlIwPSsq
— JAMA Oncology (@JAMAOnc) December 30, 2021
RCT: In patients presenting with metastatic breast cancer, early locoregional therapy for the primary site did not improve survival or quality of life.
11 Jan, 2022 | 02:29h | UTCEarly Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108) – Journal of Clinical Oncology (link to abstract – $ for full-text)
Systematic Review: First-generation cephalosporins for the treatment of complicated upper urinary tract infection in adults.
11 Jan, 2022 | 02:23h | UTC
Commentary on Twitter
Interesting! Why not?
??Systematic literature review First-generation cephalosporins mainly Cefazolin and one study Cefadroxil for the treatment of complicated upper urinary tract infection in adults
Comparators mainly 3d G
Old studies
No meta-analysis https://t.co/EHamKpfKZQ— Antibiotic Stewa®️x? Bassam Ghanem (@ABsteward) January 10, 2022
Systematic Review: The effectiveness and safety of treatments for recurrent vulvovaginal candidiasis.
11 Jan, 2022 | 02:24h | UTCTreatment for recurrent vulvovaginal candidiasis (thrush) – Cochrane Library
Review: New aspects in the management of hypertension in patients with chronic kidney disease not on renal replacement therapy.
11 Jan, 2022 | 02:22h | UTC
The ‘Ten Commandments’ of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.
11 Jan, 2022 | 02:20h | UTCRelated:
NICE Guideline | Acute heart failure: diagnosis and management.
The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention.
M-A: Fecal immunochemical test to triage patients with possible colorectal cancer symptoms.
11 Jan, 2022 | 02:18h | UTC
Commentary on Twitter
?#CuttingEdgeBlog Plain English summary?
"Worried about symptoms of bowel cancer? A simple stool test may help."@ian_bissett @SawKS88 @ChenLiu_NZ @williamxu_98 @chrisvarghese98
Blog?: https://t.co/Pb7zfsfWT3
Based on the paper ?: https://t.co/20proTApNd pic.twitter.com/IAUsHIqUrn
— BJS (@BJSurgery) January 10, 2022
Registry Study: Determinants of outcomes following surgery for type A acute aortic dissection.
11 Jan, 2022 | 02:12h | UTC
Commentary on Twitter
Determinants of outcomes following surgery for type A acute aortic dissection: the UK National Adult Cardiac Surgical Audit https://t.co/nKH9jJLjdp #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/5C5jGd4DV6
— European Society of Cardiology Journals (@ESC_Journals) September 30, 2021
Review | Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop.
11 Jan, 2022 | 02:16h | UTC
Commentary from the author on Twitter (thread – click for more)
We were asked to write about balance of harms and benefits of antidepressants based on current knowledge for @DTB_BMJ, a BMJ journal that is famously independent and does not take pharma sponsorship/advertising https://t.co/QCg7Bo1F40 1/n
— Mark Horowitz (@markhoro) December 21, 2021
RCT: Early exercise (1 week after surgery) may be safe after breast augmentation.
11 Jan, 2022 | 02:14h | UTCCommentary: Exercise Soon After Breast Plastic Surgery Is Safe, Healthy – HealthDay
RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.
11 Jan, 2022 | 02:10h | UTCHydroxyurea for primary stroke prevention in children with sickle cell anaemia in Nigeria (SPRING): a double-blind, multicentre, randomised, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)
Cohort Study: Ciprofloxacin exposure during pregnancy was not associated with miscarriage or major malformations in a nationwide study from Denmark.
11 Jan, 2022 | 02:08h | UTCCiprofloxacin exposure and adverse pregnancy outcomes: a Danish nationwide cohort study – BJOG (link to abstract – $ for full-text)
Cohort study: Among health care workers previously vaccinated with 2 doses of the Pfizer-BioNTech vaccine, receiving a third dose was associated with reduced risk of SARS-CoV-2 infection.
11 Jan, 2022 | 01:35h | UTCEditorial: Booster Vaccination to Reduce SARS-CoV-2 Transmission and Infection – JAMA
Covid-19’s Devastating Effect on Tuberculosis Care — A Path to Recovery.
11 Jan, 2022 | 01:33h | UTC
Commentary on Twitter
In @NEJM today, @TerezaKasaeva @doctorsoumya and I write about
Covid-19’s devastating impact on tuberculosis care & offer suggestions for recoveryhttps://t.co/buOEOPVWwM pic.twitter.com/BfOK3X3MuU
— Madhu Pai, MD, PhD (@paimadhu) January 5, 2022
Review: Rapid diagnostic testing for SARS-CoV-2.
11 Jan, 2022 | 01:34h | UTCRapid Diagnostic Testing for SARS-CoV-2 – New England Journal of Medicine
[Preprint] Lab study shows Omicron infection enhances neutralizing immunity against the Delta variant.
11 Jan, 2022 | 01:29h | UTCOmicron infection enhances neutralizing immunity against the Delta variant – medRxiv
Study shows Covid-19 vaccination is associated with a smaller reduction in transmission of the delta variant compared with the alpha variant.
11 Jan, 2022 | 01:31h | UTC
Commentary on Twitter
Vaccination was associated with a smaller reduction in transmission of the SARS-CoV-2 delta variant than of the alpha variant, and the effects of vaccination decreased over time. #COVID19 #IDTwitter https://t.co/giGzWSx31k pic.twitter.com/HlwBqNGFO1
— NEJM (@NEJM) January 5, 2022