Daily Archives: October 25, 2021

Opinion | COVID STEROID-2: Double the steroid, double the fun? – “Dexamethasone 6 mg/day alone is likely suboptimal for most patients with severe COVID pneumonia. Dexamethasone 12 mg/day may provide a reasonable intensity of immunomodulation”.

25 Oct, 2021 | 00:01h | UTC

COVID STEROID-2: Double the steroid, double the fun? – PulmCrit

Original study: RCT: In adults with Covid-19 and severe hypoxemia, 12 mg vs. 6 mg of Dexamethasone did not result in a statistically significant difference in the number of days alive without life support.

 

Commentary on Twitter

COVID-STEROID 2
?5% lower mortality with 12 mg dexamethasone (vs 6 mg) – which is *huge* – but p=0.09 ?
?RCTs with toci/bari show that 6 mg dex alone is suboptimal.
?If using dex monotherapy, 12 mg is now a sensible dose for sicker pts.
Fresh blog: https://t.co/oPz7vAYHGN pic.twitter.com/diDqqUxSTC

— ???? ?????? ? (@PulmCrit) October 23, 2021

 

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Review: Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity?

25 Oct, 2021 | 00:03h | UTC

Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity? – The Lancet Respiratory Medicine

 

Commentary on Twitter

New on our #COVID19 resource centre—Personal View: Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity?

Read in @LancetRespirMed: https://t.co/ZOTgVQYd6w pic.twitter.com/7BwRPLzsib

— The Lancet (@TheLancet) October 23, 2021

 

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