Daily Archives: September 28, 2021
Editorial: It’s time to send children back to school.
28 Sep, 2021 | 09:49h | UTCIt’s time to send children back to school – Nature Medicine
COVID-19 testing moves out of the clinic and into the home.
28 Sep, 2021 | 09:46h | UTCCOVID-19 Testing Moves Out of the Clinic and Into the Home – JAMA
Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.
28 Sep, 2021 | 09:51h | UTCNews release: COVID-19 has caused the biggest decrease in life expectancy since World War II – University of Oxford
Commentaries:
Life expectancy falls in 27 of 29 nations amid COVID-19 – CIDRAP
Covid has wiped out years of progress on life expectancy, finds study – The Guardian
Related:
Just how do deaths due to COVID-19 stack up?
Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.
COVID-19 has caused 6.9 million deaths globally, more than double what official reports show
Commentary on Twitter
The Covid-19 pandemic has resulted in the largest loss of life expectancy since World War II, worst among American menhttps://t.co/7eNCkwBuJA @jm_aburto @UniofOxford @OxfordDemSci @ridhikash07 @melindacmills pic.twitter.com/ckRIDD9G4m
— Eric Topol (@EricTopol) September 27, 2021
Evidence shows that, yes, masks prevent COVID-19 – and surgical masks are the way to go.
28 Sep, 2021 | 09:45h | UTCRelated: [Preprint] Largest study of masks yet details their importance in fighting Covid-19.
Functioning of the international health regulations during the COVID-19 pandemic.
28 Sep, 2021 | 09:41h | UTCFunctioning of the International Health Regulations during the COVID-19 pandemic – The Lancet
Systematic review: Can non-pharmacological measures prevent or reduce Covid-19 (SARS-CoV-2) infections in long term care facilities?
28 Sep, 2021 | 09:47h | UTC
RCT: Methylphenidate may improve apathy in patients with Alzheimer Disease.
28 Sep, 2021 | 09:06h | UTCEffect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Editorial: Methylphenidate for Apathy in Alzheimer Disease—Why Should We Care? (free for a limited period)
Commentary on Twitter
Small to medium effects of methylphenidate for apathy in AD. Good to see a positive symptomatic treatment trial but I wonder just how important the improvements are to patients and their families. https://t.co/nGSxlAntAd
— Robert Howard (@ProfRobHoward) September 27, 2021
RCT: Effect of whole-genome sequencing on the clinical management of acutely ill infants with suspected genetic disease.
28 Sep, 2021 | 09:05h | UTC
Commentaries on Twitter
This @JAMAPediatrics randomized clinical trial of acutely ill infants showed that access to whole genome sequencing doubled the proportion of patients with a precision diagnosis and a change of clinical management. https://t.co/yykog2UGLT pic.twitter.com/Gd7iuuUWII
— Muin J. Khoury (@MuinJKhoury) September 27, 2021
New study found two-times more infants in the ICU get a diagnosis and precision care when they get genomes. First-line genomes may reduce healthcare disparities by providing equitable access to dx https://t.co/FOO82Mds7D pic.twitter.com/BTb5AwsVHE
— JAMA Pediatrics (@JAMAPediatrics) September 27, 2021
Review: The biological and clinical significance of emerging SARS-CoV-2 variants.
28 Sep, 2021 | 09:43h | UTCThe biological and clinical significance of emerging SARS-CoV-2 variants – Nature Reviews Genetics
Commentary on Twitter
A Review in @NatureRevGenet describes the latest understanding of the emergence and properties of SARS-CoV-2 genetic variants, particularly those designated as WHO “variants of concern.” https://t.co/MUERXQRQxd pic.twitter.com/6dsHEMmk2p
— Nature Portfolio (@NaturePortfolio) September 22, 2021
New analysis shows use and predictors of low-value care in health systems – “Patients at health systems with smaller shares of primary care physicians and without teaching hospitals were more likely to receive low-value services”.
28 Sep, 2021 | 09:08h | UTCNews release: New analysis shows use and predictors of low-value care in health systems nationwide – Brigham and Women’s Hospital
Original study: Low-Value Care at the Actionable Level of Individual Health Systems – JAMA Internal Medicine
Author interview: Low-Value Care at the Actionable Level of Individual Health Systems
Commentary on Twitter
New study measures and reports use of 41 low-value care services + composite measure for 556 health systems across US. More low-value care in systems w ↓ PCPs, w/o major teaching hospital, HQ'ed in South+West, in areas w ↑ healthcare spending https://t.co/0qdkflxwWF
— JAMA Internal Medicine (@JAMAInternalMed) September 27, 2021
Bayesian interpretation of p values in clinical trials.
28 Sep, 2021 | 09:01h | UTCBayesian interpretation of p values in clinical trials – BMJ Evidence-Based Medicine
Commentary on Twitter
How to interpret p values in clinical trials from a Bayesian perspective? A guideline with examples by John Ferguson#OpenAccess
?https://t.co/cDMpSG5K9B pic.twitter.com/83wzpSTerV— BMJ Evidence-Based Medicine (@BMJ_EBM) September 26, 2021
RCT: Overall survival benefit with Tebentafusp in metastatic uveal melanoma.
28 Sep, 2021 | 09:03h | UTC
Commentary on Twitter
Treatment with tebentafusp resulted in longer overall survival than the control therapy among previously untreated patients with metastatic uveal melanoma. https://t.co/HnSdWItKIp pic.twitter.com/qu4huRn3Mu
— NEJM (@NEJM) September 27, 2021
Beware survivorship bias in advice on science careers – “For objective careers advice, talk to those who left science as well as those who stayed”.
28 Sep, 2021 | 08:59h | UTCBeware survivorship bias in advice on science careers – Nature
Review: Coronary artery anomalies.
28 Sep, 2021 | 09:02h | UTCCoronary Artery Anomalies – Circulation (free for a limited period)
Commentary on Twitter
#InDepth Review highlighting current diagnostic and therapeutic approaches to Coronary Artery Anomalies https://t.co/TB5HWvgHiE #AHAJournals pic.twitter.com/OaCGUNSPfW
— Circulation (@CircAHA) September 23, 2021
Review: Life-threatening skin conditions presenting to critical care.
28 Sep, 2021 | 08:57h | UTCLife-threatening skin conditions presenting to critical care – BJA Education
New guidelines to improve reporting standards of studies that investigate causal mechanisms.
28 Sep, 2021 | 09:00h | UTCNews release: New guidelines to improve reporting standards of studies that investigate causal mechanisms – University of Oxford
Original article: A Guideline for Reporting Mediation Analyses of Randomized Trials and Observational Studies: The AGReMA Statement – JAMA (free for a limited period)
Commentary: Reporting Findings From Mediation Analyses – JAMA (free for a limited period)
Commentary on Twitter (thread – click for more)
✨NEW✨ "A Guideline for Reporting Mediation Analyses of Randomized Trials and Observational Studies – The AGReMA statement" is now available @JAMA_current pic.twitter.com/nrt6grhomP
— Hopin Lee (@hopinlee) September 21, 2021
Podcast: Diabetic Pearls.
28 Sep, 2021 | 08:53h | UTC#296 Diabetes FAQ with Dr. Jeff Colburn – The Curbsiders
M-A of randomized trials: Efficacy of exercise combined with standard treatment for depression compared to standard treatment alone.
28 Sep, 2021 | 08:55h | UTC
Commentary on Twitter
Meta-analysis: Exercise combined with standard treatments for depression is more effective than standard treatments alone. https://t.co/TlePIyvzo3 pic.twitter.com/h6eRoKFLUt
— Steve Stewart-Williams (@SteveStuWill) September 18, 2021
Interactive Infographic: Milestones in diabetes.
28 Sep, 2021 | 08:58h | UTCMilestones in diabetes – Nature
Improving communication of incidental imaging findings: transforming uncertainty into opportunity.
28 Sep, 2021 | 08:50h | UTCRelated:
Meta-Analysis: Incidental Findings on MRI of Apparently Asymptomatic Adults
Review: Prevalence and Outcomes of Incidental Imaging Findings
Study: Cascades of Care After Incidental Findings
Drug-resistant malaria is gaining a foothold in Africa – “Analyses of patient blood samples suggest artemisinin effectiveness is slipping”.
28 Sep, 2021 | 08:49h | UTCDrug-resistant malaria is gaining a foothold in Africa – Science
Commentary on Twitter
Drug-evading parasites appeared in Southeast Asia in the early 2000s, eventually leading to failures of key therapies.
But the stakes are higher for Africa, home to 94% of both malaria cases and deaths worldwide in 2019. https://t.co/ILamXKP3yh
— Global Health NOW (@ghn_news) September 27, 2021
Expert Analysis: How to do emergency action planning in sports.
28 Sep, 2021 | 08:52h | UTCHow To of Emergency Action Planning – American College of Cardiology
Commentary on Twitter
In an expert analysis, @EMFried33 discusses the core principles of an emergency action plan, the value of CPR and AED training for all stakeholders in sports, & how to spot #SuddenCardiacArrest in athletes. Read more here: https://t.co/Hsq1g5gO46 #SportsCardio pic.twitter.com/YngteDFQ89
— American College of Cardiology (@ACCinTouch) September 27, 2021
Podcast: Neutropenic Fever.
28 Sep, 2021 | 08:52h | UTC#288 LIVE! Neutropenic Fever featuring Dr. Susan Seo – The Curbsiders