Daily Archives: September 24, 2021
[Preprint] PRINCIPLE RCT: Colchicine does not improve time to recovery in outpatients with Covid-19 at higher risk of complications.
24 Sep, 2021 | 10:13h | UTC
Commentary on Twitter
While COLCORONA trial found limited evidence that colchicine may reduce COVID-19 related hospitalisation/death
???@TrialPrinciple preprint
Colchicine did NOT improve time to recovery in people at higher risk of complications w COVID-19 in the communityhttps://t.co/2sUoeD7sGV pic.twitter.com/fi2THbxewW— Antibiotic Stewa®️xd ??? Bassam Ghanem (@ABsteward) September 23, 2021
Just how do deaths due to COVID-19 stack up?
24 Sep, 2021 | 10:07h | UTCJust How Do Deaths Due to COVID-19 Stack Up? – Think Global Health
Commentary on Twitter
How do deaths due to COVID-19 compare? Despite a likely undercount in many places, COVID is the leading killer in most of Latin America & Western Europe, says Chris Troeger @IHME_UW. Our interactive map ranks #COVID deaths among all causes since Jan 2020.https://t.co/U8J1uWUsgK
— Think Global Health (@ThinkGlobalHlth) September 23, 2021
How patient data underpin COVID-19 research – “Tracking the coronavirus SARS-CoV-2, developing treatments and testing vaccines have relied on access to the health data of millions of people. This massive trove could be used to understand other diseases, but not everyone is convinced”.
24 Sep, 2021 | 10:03h | UTCHow patient data underpin COVID-19 research – Nature
No, vaccinated people are not ‘just as likely’ to spread the Coronavirus as unvaccinated people.
24 Sep, 2021 | 10:06h | UTC
Commentary on Twitter
“Vaccinated people are just as likely to spread the coronavirus.”
This isn't true. But some people — even some very smart people — mistakenly believe this.
Dr. @Craig_A_Spencer explains here why, in this really good piece from @TheAtlantic.https://t.co/9D1dngt3oG
— Paul Sax (@PaulSaxMD) September 23, 2021
WHO recommends antibody treatment for COVID patients at high risk of hospital admission.
24 Sep, 2021 | 10:11h | UTCOriginal article and infographic: A living WHO guideline on drugs for covid-19 – The BMJ
Expert panel recommends against use of race in assessment of kidney function.
24 Sep, 2021 | 09:01h | UTCExpert panel recommends against use of race in assessment of kidney function – STAT
Commentary on Twitter
A Unifying Approach for GFR Estimation: Recommendations of the @nkf – @ASNKidney Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease https://t.co/0qt8F7l9Wm (FREE)#KidneyDisease #HealthEquity pic.twitter.com/QVkMnsBA6B
— AJKD (@AJKDonline) September 23, 2021
COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants.
24 Sep, 2021 | 10:02h | UTCCOVID-19 vaccines: Keeping pace with SARS-CoV-2 variants – Cell
Commentary on Twitter
COVID-19 #vaccines: Keeping pace with SARS-CoV-2 #variants. Timely commentary on understanding #immune correlates and laboratory findings in the context vaccine efficacy from @mugecevik @NathanGrubaugh @VirusesImmunity @p_openshaw https://t.co/o4GoChq5RM #COVID19 #SARSCoV2 pic.twitter.com/UuWqWa711K
— Sri Baqri (Narasimhan) (@Sri_Baqri) September 17, 2021
Review | Interplay between endocrinology, metabolism, and COVID-19 infection.
24 Sep, 2021 | 10:00h | UTCInterplay between endocrinology, metabolism, and COVID-19 infection – Clinical Medicine Journal
Landmark articles suggest eliminating race in the estimation of kidney function.
24 Sep, 2021 | 09:03h | UTCStudy 2: Race, Genetic Ancestry, and Estimating Kidney Function in CKD – New England Journal of Medicine
Commentaries:
Remove Race From Equation Used to Assess Kidney Function, Researchers Say – AJMC
Commentary on Twitter
Honored to contribute to the NEW 2021 CKD-EPI #race-free #eGFR equation in our latest research published in @NEJM today. I learned a ton about equations. Importantly, the main lesson is that #race should NOT be incorporated into #biological tools. https://t.co/RvfWWwGOox pic.twitter.com/Xub23AUXht
— Amaka Eneanya, MD, MPH (@AmakaEMD) September 23, 2021
RCT confirms antibiotics are not needed for most children with uncomplicated lower respiratory tract infection if pneumonia is not suspected clinically.
24 Sep, 2021 | 09:00h | UTC
Commentary on Twitter
#Antibiotic resistance is a global public health threat.
New trial indicates, unless pneumonia is suspected, clinicians should provide safety-netting advice but not prescribe antibiotics for most children presenting with chest infections. https://t.co/mOwLG5rZd1 #AMR pic.twitter.com/b0c7Z5flQk
— The Lancet (@TheLancet) September 23, 2021
Cohort Study: Insulin resistance linked to increased risk of major depressive disorder.
24 Sep, 2021 | 08:59h | UTCCommentaries:
Insulin Resistance Linked to Major Depressive Disorder, Dutch Study Finds – Psychiatric News Alert
Insulin resistance doubles risk of major depressive disorder – Stanford Medicine
Clinical practice guideline on immune checkpoint inhibitor-related adverse events.
24 Sep, 2021 | 08:55h | UTCRelated:
NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities (several resources on the subject)
Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment (several resources on the subject)
WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18 – In many countries, ciprofloxacin resistance was exceedingly high, and decreased susceptibility or resistance to ceftriaxone and cefixime continued to emerge.
24 Sep, 2021 | 08:53h | UTC
Large, multinational cohort suggests ondansetron use in pregnancy does not increase the risk for adverse fetal outcomes.
24 Sep, 2021 | 08:57h | UTCEditorial: Providing Data to Empower Pregnant Patients to Make Evidence-Based Choices
Commentary on Twitter
This cohort study found there was no association between ondansetron exposure during pregnancy and increased risk of fetal death, spontaneous abortion, stillbirth, or major congenital malformations compared with exposure to other antiemetic drugs. https://t.co/hDXr72Ga01
— JAMA Network Open (@JAMANetworkOpen) April 23, 2021
European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients.
24 Sep, 2021 | 08:54h | UTC
Review: Focused management of patients with severe acute brain injury and ARDS.
24 Sep, 2021 | 08:52h | UTCFocused Management of Patients with Severe Acute Brain Injury and ARDS – CHEST