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Daily Archives: August 31, 2021

Cohort study: A strategy combining a rapid antigen test and chest CT was effective in ruling out COVID-19 in the emergency department.

31 Aug, 2021 | 09:00h | UTC

Rapid Antigen Test Combined with Chest Computed Tomography to Rule Out COVID-19 in Patients Admitted to the Emergency Department – Journal of Clinical Medicine

 


WHO Issues COVID-19 Digital ‘Vaccine Pass’ Guidelines – But Stresses These Should Not be Requirements for Travel.

31 Aug, 2021 | 09:02h | UTC

WHO Issues COVID-19 Digital ‘Vaccine Pass’ Guidelines – But Stresses These Should Not be Requirements for Travel – Health Policy Watch

See guidance: Digital documentation of COVID-19 certificates: vaccination status: technical specifications and implementation guidance, 27 August 2021 – World Health Organization

 


Study shows young children gained weight during the pandemic.

31 Aug, 2021 | 08:59h | UTC

News release: Young children gained weight during the pandemic – Kaiser Permanente

Original study: Changes in Body Mass Index Among Children and Adolescents During the COVID-19 Pandemic – JAMA

 

Commentary on Twitter

 


Study demonstrates a significantly higher humoral immunogenicity induced by the SARS-CoV-2 Moderna vaccine compared with the Pfizer- BioNTech vaccine.

31 Aug, 2021 | 09:04h | UTC

Comparison of SARS-CoV-2 Antibody Response Following Vaccination With BNT162b2 and mRNA-1273 – JAMA

Related:

Moderna may be superior to Pfizer against Delta variant — breakthrough odds rise with time.

[Preprint] Pfizer vs. Moderna COVID-19 vaccine effectiveness against the Delta variant in Qatar – Effectiveness against symptomatic disease due to Delta was 53.5% for Pfizer and 84.8% for Moderna; effectiveness against severe disease due to Delta was 89.7% for Pfizer and 100.0% for Moderna.

 


Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

31 Aug, 2021 | 08:57h | UTC

Do kids get long COVID? And how often? A paediatrician looks at the data – The Conversation

Related:

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

 


Opinion | COVID vaccines: we need to find out which incentives actually work – the author argues that policies to promote vaccine uptake should be tested in randomized clinical trials.

31 Aug, 2021 | 08:56h | UTC

COVID vaccines: we need to find out which incentives actually work – The Conversation

 


#ESCCongress – 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice.

31 Aug, 2021 | 08:53h | UTC

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC) – European Heart Journal

News release: How can I avoid heart disease or stroke? – European Society of Cardiology

Key Points: 2021 ESC Guidelines on CVD Prevention in Clinical Practice – American College of Cardiology

 

Commentary on Twitter

 


#ESCCongress – RCT: Influenza vaccination early after a myocardial infarction (MI) or in high-risk coronary heart disease resulted in a lower risk of a composite of all-cause death, MI, or stent thrombosis compared with placebo.

31 Aug, 2021 | 08:52h | UTC

Influenza Vaccination after Myocardial Infarction: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial – Circulation

Commentaries:

IAMI: Influenza Vaccine Beneficial for Post-MI Patients – TCTMD

Influenza Vaccination After Myocardial Infarction – IAMI – American College of Cardiology

Flu vaccine after heart attack reduces risk of death – Cardiovascular Business

 

Commentary on Twitter

 


#ESCCongress – RCT: In older patients with hypertension, intensive treatment with a SBP target of 110 to less than 130 mm Hg resulted in a lower incidence of cardiovascular events than standard treatment with a target of 130 to less than 150 mm Hg.

31 Aug, 2021 | 08:49h | UTC

Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

STEP: Aggressive BP Management in Older Chinese Patients With HTN Improved CV Outcomes vs. Standard Care – American College of Cardiology

STrategy of blood pressure intervention in the Elderly hypertensive Patients – STEP – American College of Cardiology

 

Commentary on Twitter

 


#ESCCongress – RCT: In individuals at risk for stroke, screening for atrial fibrillation using loop recorder resulted in a three-times increase in atrial fibrillation detection and anticoagulation initiation but did not reduce the risk of stroke or systemic arterial embolism.

31 Aug, 2021 | 08:50h | UTC

Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial – The Lancet

News release: Continuous heart rhythm monitoring and treatment if indicated does not prevent stroke – European Society of Cardiology

Commentary: Atrial Fibrillation Detected by Continuous ECG Monitoring Using Implantable Loop Recorder to Prevent Stroke in High-Risk Individuals – LOOP – American College of Cardiology

Related: #ESCCongress – RCT: Small benefit from systematic screening for atrial fibrillation in older adults – After a median follow-up of 6.9 y there were fewer events (stroke, embolism, bleeding, and death) in the intervention group (31·9%) vs. control group (33·0%).

 


#ESCCongress – M-A: Polypills with and without aspirin substantially reduce cardiovascular disease, myocardial infarction, stroke, revascularization, and cardiovascular death in primary cardiovascular disease prevention.

31 Aug, 2021 | 08:47h | UTC

Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentary: Combo therapy cuts risk of heart attacks and strokes in half – McMaster University

Related:

Opinion: A new important study supports wider use of the polypill

#AHA20 – Randomized trial: A polypill comprising statins, multiple blood pressure lowering drugs, and aspirin prevents cardiovascular events among patients at intermediate cardiovascular risk

Perspective: Are Polypills and Population-based Treatment the Next Big Things?

The Polypill Revisited: Why We Still Need Population-Based Approaches in the Precision Medicine Era

Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population

Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases

Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart

Perspective: The Polypill and the Long Journey to Major Impact

Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care

 


Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes – An HbA1c < 6.5% measured at least 3 months after cessation of glucose-lowering pharmacotherapy is suggested as the usual diagnostic criteria.

31 Aug, 2021 | 08:45h | UTC

Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes – The Journal of Clinical Endocrinology & Metabolism

News release: International Experts Outline Diabetes Remission Diagnosis Criteria – Endocrine Society

 


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