Daily Archives: July 18, 2021
RCT: more data showing Azithromycin is not better than placebo in patients with Covid-19.
18 Jul, 2021 | 23:54h | UTCRelated: RCT: Another study shows Azithromycin does not improve outcomes in patients with Covid-19. (several articles on the subject)
Commentary on Twitter
Among outpatients with #SARSCoV2 infection, treatment with a single dose of oral #azithromycin compared with placebo did not result in a greater likelihood of being free of symptoms at day 14 https://t.co/dYDcSyGtwd #COVID19
— JAMA (@JAMA_current) July 16, 2021
Review: Symptoms, complications and management of long COVID.
18 Jul, 2021 | 23:46h | UTCCommentary: Long COVID: More likely in patients with 5+ symptoms in first week of infection – SAGE Publications
Commentary on Twitter
Pooled prevalence data in this review showed the 10 most prevalent reported symptoms of long covid were: fatigue, shortness of breath, muscle pain, joint pain, headache, cough, chest pain, altered smell, altered taste and diarrhoea.
https://t.co/ww5HM1s7vm— KK Cheng (@KKCheng4) July 16, 2021
Position Paper: Recommendations for the use of topical inhalant budesonide in COVID-19.
18 Jul, 2021 | 23:53h | UTCRecommendations for use of topical inhalant budesonide in COVID-19 – HNO
Related: RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19 AND Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19
Studies elucidate poorly understood long COVID.
18 Jul, 2021 | 23:42h | UTCStudies elucidate poorly understood long COVID – CIDRAP
Long Covid: fatigue, post-exertional malaise, and cognitive dysfunction are the most common symptoms, according to an international survey.
18 Jul, 2021 | 23:44h | UTCCommentaries: Identification of over 200 long COVID symptoms prompts call for UK screening programme – University College London AND A survey of long-haulers found 66 symptoms that lasted more than 6 months. Tiredness and brain fog were most common. – Insider AND Long Covid has more than 200 symptoms, study finds – The Guardian
CDC warns Covid-19 vaccines might not protect people who are immunocompromised – “CDC is looking into ongoing research exploring the possibility that immunocompromised could benefit from an additional dose”.
18 Jul, 2021 | 23:38h | UTCCDC warns Covid-19 vaccines might not protect people who are immunocompromised – CNN
Fauci says natural origins theory of coronavirus is still the most likely.
18 Jul, 2021 | 23:40h | UTCFauci says natural origins theory of coronavirus is still the most likely – CNN
Related article (preprint): The Origins of SARS-CoV-2: A Critical Review – Zenodo
See also: A Group of Scientists Presses a Case Against the Lab Leak Theory of Covid – The New York Times (a few articles per month are free) AND Leading scientists push back against Wuhan lab leak theory – The Age
Related: Opinion | The Covid-19 lab leak theory is a tale of weaponized uncertainty.
WHO publishes new Consolidated HIV guidelines for prevention, treatment, service delivery & monitoring.
18 Jul, 2021 | 23:22h | UTC
Review: Acute kidney injury.
18 Jul, 2021 | 23:18h | UTCAcute kidney injury – Nature Reviews Disease Primers (free for a limited period)
Commentary on Twitter
Get Primed on #AcuteKidneyInjury with our NEW PrimeView, FREE to download this week https://t.co/4RAOOaB8ep pic.twitter.com/d5iHCcqJwY
— Nature Reviews Disease Primers (@DiseasePrimers) July 15, 2021
Review: Parkinson disease-associated cognitive impairment.
18 Jul, 2021 | 23:17h | UTCParkinson disease-associated cognitive impairment – Nature Reviews Disease Primers (free for a limited period)
Infographic: Parkinson disease-associated cognitive impairment
Review: Glucocorticoid induced adrenal insufficiency.
18 Jul, 2021 | 23:15h | UTCGlucocorticoid induced adrenal insufficiency – The BMJ
Commentary on Twitter
◾ What factors affect the risk of Glucocorticoid induced adrenal insufficiency?
◾ What regimen can be used for glucocorticoid taper?
◾ How can adrenal function recovery be best assessed?Read our latest clinical review to find out: https://t.co/m814c1rgIs
— The BMJ (@bmj_latest) July 13, 2021
Study: Pooled saliva analysis is a low-cost and effective strategy for surveillance of Covid-19 in schools and universities and allows to rapidly assess transmission and adjust prevention protocols.
18 Jul, 2021 | 23:37h | UTCRelated: Pooling of Samples for Testing for SARS-CoV-2 in Asymptomatic People AND Implementation of a Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections on a College Campus — Duke University, Durham, North Carolina, August 2–October 11, 2020 – CDC Morbidity and Mortality Weekly Report
AHA/ASA Scientific Statement: Primary Care of Adult Patients After Stroke.
18 Jul, 2021 | 23:20h | UTCNews release: Comprehensive primary care is vital to holistic care and optimal recovery after a stroke – American Heart Association
Commentary on Twitter
Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association https://t.co/moIZ1W2cXL @American_Heart @American_Stroke pic.twitter.com/jWOK8Fz0vM
— Stroke AHA/ASA (@StrokeAHA_ASA) July 15, 2021
M-A: benefit-to-harm balance of statins in primary prevention of cardiovascular disease generally favorable.
18 Jul, 2021 | 23:16h | UTCNews release: New study suggests benefit-to-harm balance of statins for healthy adults ‘generally favorable’ – BMJ
Commentary on Twitter
Statins are associated with a small increased risk of side effects in patients without a history of heart disease, but these effects are mild compared with the potential benefits of treatment in preventing major cardiovascular events, say researchers https://t.co/Yvn7Ojtx2F
— The BMJ (@bmj_latest) July 17, 2021
RCT: No benefit from platelet-rich plasma injection for patients with debilitating Achilles tendinopathy.
18 Jul, 2021 | 23:13h | UTCEffect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: No benefit from PRP treatment for patients with debilitating Achilles tendon pain – University of Warwick
Commentary on Twitter
A single injection of platelet-rich plasma compared with a sham injection did not significantly reduce #Achillestendon dysfunction https://t.co/K4YKHSbxZY
— JAMA (@JAMA_current) July 13, 2021
Body-mass index and diabetes risk in 57 low-income and middle-income countries – “Optimal BMI thresholds for diabetes screening ranged from 23·8 kg/m2 among men in east, south, and southeast Asia to 28·3 kg/m2 among women in the Middle East and north Africa and in Latin America and the Caribbean”.
18 Jul, 2021 | 23:10h | UTCBody-mass index and diabetes risk in 57 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 685 616 adults – The Lancet (link to abstract – $ for full-text)
Related: Study shows BMI cut-offs for obesity and diabetes risk do not work for non-white populations. AND Study: Certain Racial/Ethnic Groups More Likely to Have Diabetes and Prediabetes at Lower Weights