Daily Archives: May 20, 2021
Cohort study: 14% of adults aged 65 years or less who were infected with SARS-CoV-2 had at least one new type of clinical sequelae that required medical care after the acute phase of the illness.
20 May, 2021 | 08:59h | UTCEditorial: Unpacking post-covid symptoms – The BMJ
Commentary on Twitter (thread – click for more)
After covid infections, 14% of >266,000 people, age ≤ 65, developed at least 1 sequelae that required medical care #LongCovid Just out @bmj_latest @OptumLabs @mlipsitch Risk increased w/ pre-existing conditions but also found in healthy, age < 50 https://t.co/h8IlnRNp2v pic.twitter.com/e15uSj9BXN
— Eric Topol (@EricTopol) May 19, 2021
FDA In Brief: FDA advises against use of SARS-CoV-2 antibody test results to evaluate immunity or protection from COVID-19, including after vaccination.
20 May, 2021 | 08:55h | UTC
Commentary on Twitter (thread – click for more)
Today, we issued a safety communication notifying the public and providers that results from SARS-CoV-2 antibody tests should not be used to evaluate immunity or protection from #COVID19 at any time – especially after receiving a #COVID19 vaccination. https://t.co/KlywV04WYO pic.twitter.com/TPdIVxWzSh
— U.S. FDA (@US_FDA) May 19, 2021
Systematic review and meta-analysis of observational studies suggest low-dose aspirin may be of benefit for patients with Covid-19 – the finds require further investigation in randomized studies.
20 May, 2021 | 08:54h | UTC
One year after hospital discharge due to SARS-CoV-2 Infection, the prevalence of long-term cough, chest pain, dyspnea, and fatigue was 2.5%, 6.5%, 23.3%, and 61.2%, respectively
20 May, 2021 | 08:57h | UTCPrevalence of Post-COVID-19 Cough One Year After SARS-CoV-2 Infection: A Multicenter Study – Lung
COVID vaccines: the danger of journals being seen as substitute regulators – “the peer-review process is not adequate to evaluate a new vaccine in the way that a regulator can”.
20 May, 2021 | 08:51h | UTCCOVID vaccines: the danger of journals being seen as substitute regulators – The Conversation
Related: Covid-19: Sputnik vaccine rockets, thanks to Lancet boost
SPRINT Trial final report: targeting a systolic BP of less than 120 mm Hg in patients at increased CV risk is associated with improved CV and mortality outcomes but increases the risk of serious adverse events.
20 May, 2021 | 08:36h | UTC
Characteristics associated with Multisystem Inflammatory Syndrome among adults with SARS-CoV-2 infection
20 May, 2021 | 08:52h | UTCCommentary: COVID-related inflammatory syndrome looks different in adults – CIDRAP
M-A: Psychologic treatment of depression compared with pharmacotherapy and combined treatment in primary care – Psychotherapy has comparable effects to those of pharmacotherapy, and combined treatment might be better than either psychotherapy or pharmacotherapy alone.
20 May, 2021 | 08:34h | UTC
Commentary on Twitter
https://twitter.com/pimcuijpers/status/1391999860505825286
Systematic review: Prognostic factors for pain chronicity in low back pain – “Higher pain intensity, higher body weight, carrying heavy loads at work, difficult working positions, and depression were the most frequently observed risk factors for chronic low back pain”
20 May, 2021 | 08:32h | UTCPrognostic factors for pain chronicity in low back pain: a systematic review – Pain Reports
Global survey finds 44% of cardiologists report a hostile work environment. Higher rates were found among women (68%) vs. men (37%).
20 May, 2021 | 08:35h | UTCGlobal Prevalence and Impact of Hostility, Discrimination, and Harassment in the Cardiology Workplace – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Editorial: Hostile Work Environment: A Case of the Emperor’s New Clothes
Commentary: Hostility Is Common in Cardiology: Can a New ACC/AHA Statement Help? – TCTMD
Commentary on Twitter
Global Prevalence and Impact of Hostility, Discrimination, and Harassment in the Cardiology Workplace – PubMed. A global problem for cardiology….What would you do… if it was career damaging to say nothing…and career damaging to speak up? https://t.co/uutfsMXOsx
— A/Prof Sonya Burgess (@drsonyaburgess) May 15, 2021
A pharmacist-led penicillin allergy assessment program can delabel many “penicillin allergic” patients through allergy histories and penicillin skin testing. The program was associated with reduced use of high Clostridioides difficile infection–risk antibiotics.
20 May, 2021 | 08:30h | UTC
Commentaries on Twitter
🆕💥💥 @jamanetworkopen
Evaluation of a Pharmacist-Led Penicillin Allergy Assessment Program and Allergy Delabeling in a 3ry Care Hospital
Phase 1 : Allergy histories
Phase 2 :Allergy histories +Penicillin Skin Testing #IDTwitter https://t.co/pZfVf8TJIn pic.twitter.com/2VvnaCayqj— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 13, 2021
This cross-sectional study found pharmacist-driven allergy assessments may help improve antibiotic selection and clinical outcomes for patients and hospitals https://t.co/io5LcU9U9U
— JAMA Network Open (@JAMANetworkOpen) May 13, 2021
ESC Comprehensive review: Update on management of hypokalemia and goals for the lower potassium level in patients with cardiovascular disease.
20 May, 2021 | 08:26h | UTC
Commentary on Twitter
Learn about the management of hypokalemia: a comprehensive review from the ESC WG on cardiovascular pharmacotherapy https://t.co/MkwOZyvUJA@AgewallStefan @GianluSava #EHJPharmacotherapy #cardiotwitter pic.twitter.com/tUFVmycwHa
— European Society of Cardiology Journals (@ESC_Journals) May 15, 2021
24-week randomized controlled trial: Mixed tree nut snacks resulted in similar weight loss and increased satiety compared to refined carbohydrate snacks in a weight loss and maintenance program.
20 May, 2021 | 08:28h | UTCCommentary: Mixed tree nut snacks result in significant weight loss and improved satiety – News Medical
M-A: Compared to cefazolin alone, pre-incision cefazolin + adjunctive prophylaxis with macrolides or metronidazole significantly reduces the incidence of post-cesarean surgical site infection and hospital stay.
20 May, 2021 | 08:19h | UTCPre-incision Adjunctive Prophylaxis for Cesarean Sections: A Systematic Review and Meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
RCT: Reduced-intensity chemotherapy among older and frail patients with advanced gastroesophageal cancer provides an improved patient experience with no significant detriment in cancer control.
20 May, 2021 | 08:18h | UTC
Commentary on Twitter
The GO2 trial tested reduced intensity of chemo for pts w adv gastroesophageal cancer & found reducing intensity led to comparable survival but w improved patient experience, & decision-making can be enhanced using geriatric assessment https://t.co/DtZOXcozo7 #GeriOnc
— JAMA Oncology (@JAMAOnc) May 13, 2021
ERS clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years.
20 May, 2021 | 08:21h | UTC
Randomized trial long-term results confirm the benefits of neoadjuvant chemoradiotherapy plus surgery for esophageal cancer
20 May, 2021 | 08:16h | UTC
Commentaries on Twitter
Out at @ASCO_pubs
🔟yr Outcome of Neoadj #Chemoradiotherapy➕Surgery for #EsophagealCancer☑️Show OS benefit in locally advanced resectable esophageal or junctional #Cancer who receive preop chemorad🧪☢️ According to CROSS, persists at least🔟years‼️https://t.co/yJSibSveAh pic.twitter.com/UssnzuFiEe
— Gil Morgan, MD (@weoncologists) May 14, 2021
Survival benefit of preoperative chemoradiotherapy for patients with esophageal cancer persists – 10-year outcome of the CROSS trial https://t.co/s02sMVpYhI #esocsm #JCO @ErasmusMC @bmeyck pic.twitter.com/2JwV0iOvoB
— Journal of Clinical Oncology (@JCO_ASCO) May 5, 2021
Systematic review: Autoimmune encephalitis related to cancer treatment with immune checkpoint inhibitors – nivolumab was responsible for 61% of cases; onset occurred after a median of 3.5 treatment cycles, but very early and late presentations were common
20 May, 2021 | 08:13h | UTCAutoimmune Encephalitis Related to Cancer Treatment With Immune Checkpoint Inhibitors: Systematic Review – Neurology (link to abstract – $ for full-text)