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Daily Archives: May 12, 2021

Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).

12 May, 2021 | 08:55h | UTC

Eight out of ten people hospitalized with COVID-19 develop neurological problems – University of Pittsburgh

Original study: Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19—A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium – JAMA Network Open

Related: [Preprint] Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies – up to one-third of COVID-19 patients analyzed in this review, 89% of whom were hospitalized, experienced at least one neurological manifestation

 


Pfizer COVID-19 shot expanded to US children as young as 12.

12 May, 2021 | 08:53h | UTC

Pfizer COVID-19 shot expanded to US children as young as 12 – Associated Press

Counterpoint: Covid vaccines for children should not get emergency use authorization – The BMJ Opinion

Commentaries: Covid-19: FDA authorises Pfizer vaccine for children 12-15 – The BMJ AND Expert reaction to U.S. FDA authorising Pfizer-BioNTech COVID-19 vaccine for emergency use in adolescents – Science Media Centre

 


Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

12 May, 2021 | 08:54h | UTC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – Applied and Environmental Microbiology

Commentary: COVID-19 wastewater testing proves effective in new study – University of Virginia

Related: The myriad ways sewage surveillance is helping fight COVID around the world – Nature

 


Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – Approximately 1 in 5 were admitted within 14 days. Higher oxygen saturation was associated with decreased odds of transfer, whereas higher comorbidity burden was associated with increased risk.

12 May, 2021 | 08:50h | UTC

Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – American College of Physicians

Original study: Factors Associated With Risk for Care Escalation Among Patients With COVID-19 Receiving Home-Based Hospital Care – Annals of Internal Medicine

Related: Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient

 


Analysis: Quality improvement at times of crisis.

12 May, 2021 | 08:48h | UTC

Quality improvement at times of crisis – The BMJ

Related: Report: The role of improvement during the response to COVID-19 – The Health Foundation

 

Commentary on Twitter (thread – click for more)

 


Population-based cohort study: Non-hospitalized COVID-19 patients have low-risk of serious long-term effects, but visits to general practitioners and outpatient hospital visits are increased.

12 May, 2021 | 08:47h | UTC

Post-acute effects of SARS-CoV-2 infection in individuals not requiring hospital admission: a Danish population-based cohort study – The Lancet Infectious Diseases

Commentaries: Non-hospitalized COVID-19 patients: Low-risk of serious long-term effects, but more visits to doctor – The Lancet AND Any COVID-19 Infection Raises Odds for Lingering Symptoms, Study Finds – HealthDay AND Those with mild COVID-19 seek more primary care than uninfected peers – CIDRAP

 


M-A: Epidemiology and outcomes of COVID-19 in HIV-infected individuals – HIV is a significant risk factor for acquiring SARS-CoV-2 infection and is associated with a higher risk of mortality.

12 May, 2021 | 08:51h | UTC

Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis – Scientific Reports

Commentary: People living with HIV more likely to get sick with, die from COVID-19 – Penn State

Related: Overview of SARS-CoV-2 infection in adults living with HIV – Low CD4 cell counts, or untreated HIV infection is associated a more severe clinical course

 


Coronavirus variants are spreading in India — what scientists know so far.

12 May, 2021 | 08:44h | UTC

Coronavirus variants are spreading in India — what scientists know so far – Nature

 


[Preprint] Meta-analysis of risk of vaccine-induced immune thrombotic thrombocytopenia following ChAdOx1-S recombinant vaccine – Overall risk is 1 in 139,000; for age 65 and over, about 1 in 1,000,000; for age under 55, between 1 in 20,000 to 60,000.

12 May, 2021 | 08:45h | UTC

Meta-Analysis of Risk of Vaccine-Induced Immune Thrombotic Thrombocytopenia Following ChAdOx1-S Recombinant Vaccine – medRxiv

 


COVID-19 oxygen needs in low- and middle-income countries have tripled in just three months – where are solutions?

12 May, 2021 | 08:43h | UTC

COVID-19 Oxygen Needs in Low- and Middle-Income Countries Have Tripled in Just Three Months – Where are Solutions? – Health Policy Watch

 


Study shows BMI cut-offs for obesity and diabetes risk do not work for non-white populations.

12 May, 2021 | 08:41h | UTC

Study shows BMI cut offs for obesity and diabetes risk do not work for non-white populations – European Association for the Study of Obesity

Original study: Ethnicity-specific BMI cutoffs for obesity based on type 2 diabetes risk in England: a population-based cohort study – The Lancet Diabetes & Endocrinology

 


Guideline: SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes – This guidance recommends a risk-based approach, advising against starting SGLT-2 inhibitors or GLP-1 receptor agonists in patients with three or fewer cardiovascular risk factors and without established CVD or CKD.

12 May, 2021 | 08:42h | UTC

SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes: a clinical practice guideline – The BMJ

Editorial: Newer drug treatments for type 2 diabetes

 

Commentary on Twitter

 


RCT: An internet-delivered cognitive behavioral therapy (CBT) program followed by in-person CBT if necessary is noninferior to in-person CBT for the treatment of obsessive-compulsive disorder symptoms in children and adolescents.

12 May, 2021 | 08:39h | UTC

Effect of an Internet-Delivered Stepped-Care Program vs In-Person Cognitive Behavioral Therapy on Obsessive-Compulsive Disorder Symptoms in Children and Adolescents: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Digital Interventions for Adults With Symptoms of Depression and Children and Adolescents With Symptoms of Obsessive-Compulsive Disorder

News release: Online CBT effective against OCD symptoms in the young – Karolinska Institutet

 


Review: Diagnosis and management of headache.

12 May, 2021 | 08:36h | UTC

Diagnosis and Management of Headache: A Review – JAMA (free for a limited period)

Audio clinical review: Diagnosis and Management of Headache, Part 1 – JAMA

 


RCT: Among adults with idiopathic pulmonary fibrosis, antimicrobial therapy with co-trimoxazole or doxycycline is not associated with improved outcomes.

12 May, 2021 | 08:37h | UTC

Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial – JAMA (free for a limited period)

 

Commentary on Twitter

 


Perspective | 12 things to do to improve wellbeing in the ICU.

12 May, 2021 | 08:30h | UTC

12 Things to Do to Improve Wellbeing in the ICU – ICU Management & Practice

 


Perspective | Top five priorities for a new ICU director during the first year.

12 May, 2021 | 08:33h | UTC

Top Five Priorities for a New ICU Director During the First Year – ICU Management & Practice

 


Review: Neurologic assessment of the neurocritical care patient.

12 May, 2021 | 08:24h | UTC

Neurologic Assessment of the Neurocritical Care Patient – Frontiers in Neurology

 


Review: The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury.

12 May, 2021 | 08:27h | UTC

The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury – Canadian Journal of Anesthesiology

 


Perspective | The essentials for a humanized ICU.

12 May, 2021 | 08:28h | UTC

The Essentials for a Humanised Intensive Care Unit (H-ICU) – ICU Management & Practice

 


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