Daily Archives: March 5, 2021
Perspective | COVID-19 in 2021—Continuing Uncertainty
5 Mar, 2021 | 08:52h | UTCCOVID-19 in 2021—Continuing Uncertainty – JAMA
RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19
5 Mar, 2021 | 08:53h | UTCCommentaries: Ivermectin: Yet Another Fad Runs Into The Brick Wall Known As “Actual Science” – Brief-19 AND Ivermectin doesn’t speed recovery from mild COVID-19, study shows – CIDRAP
Video: Coronavirus Variants
5 Mar, 2021 | 08:50h | UTC
How well does the AstraZeneca vaccine work? An expert reviews the current evidence
5 Mar, 2021 | 08:49h | UTC
Some experience delayed rash after Moderna shot, study says
5 Mar, 2021 | 08:44h | UTCSome Experience Delayed Rash After Moderna Shot, Study Says – Bloomberg
Original study: Delayed Large Local Reactions to mRNA-1273 Vaccine against SARS-CoV-2 – New England Journal of Medicine
‘When will it end?’: How a changing virus is reshaping scientists’ views on COVID-19
5 Mar, 2021 | 08:42h | UTC‘When will it end?’: How a changing virus is reshaping scientists’ views on COVID-19 – Reuters
A Nurse’s Guide to COVID-19
5 Mar, 2021 | 08:43h | UTCA Nurse’s Guide to COVID-19 – American Journal of Nursing
An review for nurses of the care of hospitalized adults with COVID-19, including pharmacological management, critical illness management, oxygen therapy, prone positioning, and investigational agents. (CE credit available)https://t.co/k09QZW0NrT
— AmJNurs (@AmJNurs) March 1, 2021
The short-term, middle-term, and long-term future of the coronavirus
5 Mar, 2021 | 08:38h | UTCThe short-term, middle-term, and long-term future of the coronavirus – STAT
Lung transplants after Covid-19 raise difficult issues
5 Mar, 2021 | 08:36h | UTCLung transplants after Covid-19 raise difficult issues – STAT
Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance
5 Mar, 2021 | 08:35h | UTCRecommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit
Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
RCT: Safety of combined division vs. separate division of the splenic vein in patients undergoing distal pancreatectomy
5 Mar, 2021 | 08:25h | UTCCommentaries: An Evidence-Based Beneficial Shortcut for Distal Pancreatic Resection – JAMA Surgery AND Surgical Shortcut Noninferior to Standard Technique for Pancreatic Resection – Physician’s Weekly
Commentary on Twitter
Isolating the splenic vein from the pancreatic parenchyma is deemed unnecessary https://t.co/y4pE5632m4 pic.twitter.com/wumc5gopQs
— JAMA Surgery (@JAMASurgery) March 3, 2021
Scientific Statement: Invasive management of acute myocardial infarction complicated by cardiogenic shock
5 Mar, 2021 | 08:33h | UTC
ACG Clinical Guidelines: Start colorectal cancer screening at 45
5 Mar, 2021 | 08:31h | UTCACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology
Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45
Systematic Review | Automated-Entry Patient-Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes
5 Mar, 2021 | 08:21h | UTCFull report: Automated-Entry Patient Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes
Systematic Review: Different classes of antibiotics given to women routinely for preventing infection at cesarean section
5 Mar, 2021 | 08:27h | UTC
RCT: No benefit from oral corticosteroids following endoscopic sinus surgery for chronic rhinosinusitis without nasal polyposis
5 Mar, 2021 | 08:22h | UTC
Commentary on Twitter
Should you use oral steroids after sinus surgery for chronic rhinosinusitis w/o polyps? Steroids may have no benefit (and some risk!) as found in this double-blinded placebo-controlled randomized trial conducted by @StanfordMed https://t.co/mgtF3FYiVs
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) March 4, 2021
Working toward the triple bottom line in surgery to limit the impact of surgery on the environment
5 Mar, 2021 | 08:18h | UTCWorking Toward the Triple Bottom Line in Surgery – NEJM Catalyst
Related: Effects Of Surgery On A Warming Planet: Can Anesthesia Go Green? – NPR AND Anaesthetic gases, climate change, and sustainable practice – The Lancet Planetary Health AND Greenhouse gases: the choice of volatile anesthetic does matter – Canadian Journal of Anesthesiology AND People, planet and profits: the case for greening operating rooms – Canadian Medical Association Journal (free)
Commentary on Twitter
Health care produces significant greenhouse gas emissions and waste, with operating rooms producing a disproportionate share. Incorporating the #TripleBottomLine can reduce the impact: https://t.co/yp8MtO3mKb @EmilyHazelJohn1 @Gifty_Kwakye_MD @ChrisGMyers @AmirGhaferi
— NEJM Catalyst (@nejmcatalyst) January 25, 2021
An evidence review of low-value care recommendations: Inconsistency and lack of economic evidence considered
5 Mar, 2021 | 08:16h | UTC
Commentaries on Twitter
Important new work from our @TuftsCEVR team — low value care is determined inconsistently and infrequently considers $$$ when doing so. Thanks to @ddkim62 and Lauren Do for leading this effort and @a_spratt and @Arnold_Ventures for supporting it! https://t.co/1YXd9X5qJk
— Dan Ollendorf (@dollendorf) February 24, 2021
In our new @JournalGIM paper led by @ddkim62 a review of 1167 “low-value care” recommendations across five US organizations found evidentiary rationales for low-value care vary substantially, with most recommendations relying on clinical evidence. https://t.co/cdbMTPps73
— CEVR (@TuftsCEVR) February 24, 2021
Study: Proton pump inhibitors may negatively impact the outcomes of infliximab therapy in patients with inflammatory bowel disease
5 Mar, 2021 | 08:17h | UTCThe influence of proton pump inhibitor therapy on the outcome of infliximab therapy in inflammatory bowel disease: a patient-level meta-analysis of randomised controlled studies – Gut (link to abstract – $ for full-text)
Commentary on Twitter
PPI use in IBD: should we be concerned? ⚠️ ?
? meta-analysis in @Gut_BMJ concludes that patients with IBD taking PPIs have ⬆️ hospitalisation rates and are less likely to achieve remission on while on infliximab https://t.co/PKuRNatMNO pic.twitter.com/KxAiI1q2Hp
— Keith Siau (@drkeithsiau) December 24, 2020
Systematic review: Atovaquone‐proguanil for treating uncomplicated Plasmodium falciparum malaria
5 Mar, 2021 | 08:13h | UTCAtovaquone‐proguanil for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library
Meta-analysis: Comparison of Treatments for Frozen Shoulder
5 Mar, 2021 | 08:19h | UTCCommentary: Can IA Corticosteroids Turn Up the Heat on Frozen Shoulder Tx? – Physician’s Weekly
Related: Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial – The Lancet (link to abstract – $ for full-text)
Respiratory microbiome in mechanically ventilated patients: a narrative review
5 Mar, 2021 | 08:14h | UTC
Commentary on Twitter
Respiratory microbiome on mechanical ventilation:
➡️definition
➡️state of the art: lung bacterial microbiota in #ICU, invasive mechanical ventilation, #ARDS, lung nosocomial infections & VAP, lung mycobiota, virome
➡️perspectives & clinical applicationshttps://t.co/fO7ggoJNUk pic.twitter.com/0W8hLNkuSO— Intens Care Med (@yourICM) February 9, 2021
Long‐term effects of weight‐reducing drugs in people with hypertension
5 Mar, 2021 | 08:12h | UTCLong‐term effects of weight‐reducing drugs in people with hypertension – Cochrane Library
Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study
5 Mar, 2021 | 08:10h | UTCGlobal patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Global thyroid cancer overdiagnosis in children and adolescents – MDEdge (free registration required) AND Global Thyroid Cancer Overdiagnosis in Children and Adolescents – Medscape (free registration required)
Commentary on Twitter
New #IARCpaper shows the incidence of thyroid cancer in children & adolescents, a rare condition everywhere before 2000, has increased rapidly in recent years in many countries, & suggests overdiagnosis is likely to be the main driver of these increases https://t.co/1ct8iEJSty pic.twitter.com/JIjBBAyKNv
— IARC (@IARCWHO) January 20, 2021
WHO Action Framework: Leveraging vaccines to reduce antibiotic use and prevent antimicrobial resistance
5 Mar, 2021 | 08:08h | UTC