Daily Archives: October 16, 2020
[Preprint] WHO SOLIDARITY trial results published; Remdesivir, Hydroxychloroquine, Lopinavir, and Interferon do not improve outcomes in Covid-19
16 Oct, 2020 | 09:42h | UTCRepurposed antiviral drugs for COVID-19; interim WHO SOLIDARITY trial results – medRxiv
Commentary: Remdesivir and interferon fall flat in WHO’s megastudy of COVID-19 treatments – Science
Commentaries on Twitter
Results of the @WHO SOLIDARITY trial:
4 drugs tested in 11,266 patients with COVID in 405 hospitals in 30 countries:
– hydroxychloroquine
– lopinavir
– remdesevir
– interferonNo clear benefit of any of them on survival. https://t.co/ohtTAFaSnc pic.twitter.com/2fO9E8zs8h
— Martin Landray (@MartinLandray) October 16, 2020
This is blockbuster from @WHO: 'Remdesivir, Hydroxychloroquine, Lopinavir and Interferon regimens have little or no effect on hospitalized COVID-19, as indicated by mortality, initiation of ventilation and duration of hospital stay. @medrxivpreprint https://t.co/aNGLzLL5uW pic.twitter.com/daOAMVW62u
— Harlan Krumholz (@hmkyale) October 15, 2020
Scientific consensus on the COVID-19 pandemic: we need to act now
16 Oct, 2020 | 09:41h | UTCScientific consensus on the COVID-19 pandemic: we need to act now – The Lancet
Viewpoint: Sensible medicine—balancing intervention and inaction during the COVID-19 pandemic
16 Oct, 2020 | 09:38h | UTCSensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic – JAMA
Author interview: Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic
Commentary on Twitter
Has #COVID19 changed how you practice #medicine?
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More Aggressive? Gentle? Humble? or Nihilistic?
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Check out @JAMA_current elevating a discussion of Sensible Medicine.https://t.co/IfXVktCMJb @UPMC @UPMCnews @ErinMcCreary @PittCCM @PittTweet— Christopher Seymour (@seymoc) October 15, 2020
Act now, wait for perfect evidence later, says ‘high priestess’ of U.K. COVID-19 masking campaign
16 Oct, 2020 | 09:37h | UTC
Commentary on Twitter
Profile of @trishgreenhalgh, whose laudable and herculean efforts have favorably influenced our response to the pandemic @ScienceMagazine @UniofOxford https://t.co/t4yTFgmbr2 by @EllenRuppelShel
“As scientists, our goal must be to cut through the rubbish.”— Eric Topol (@EricTopol) October 15, 2020
Researchers worldwide fight to work and teach amid COVID-19
16 Oct, 2020 | 09:35h | UTCResearchers worldwide fight to work and teach amid COVID-19 – Nature
NEW Special issue of The Global Burden of Disease Study 2019
16 Oct, 2020 | 09:31h | UTCHomepage: Global Burden of Disease Study 2019 – The Lancet
Editorial: Global health: time for radical change? – The Lancet
Commentary on Twitter
NEW Special issue of #GBDStudy 2019: 286 causes of death, 369 diseases & injuries, 87 risk factors in 204 countries & territories—data reveal how the world’s population was prepared in terms of underlying health for #COVID19 pandemic https://t.co/Af7hOlLFoJ pic.twitter.com/9kSeyB77Fv
— The Lancet (@TheLancet) October 15, 2020
Cochrane living systematic review: Not enough evidence to recommend convalescent plasma for people with COVID‐19
16 Oct, 2020 | 09:34h | UTC
Commentary on Twitter
Just updated: @CochraneCollab living review investigates the use of convalescent plasma to treat people with COVID-19: https://t.co/Or5qmxki8H “We remain very uncertain about the effectiveness & safety of using convalescent plasma for people with #COVID19".
— The Cochrane Library (@CochraneLibrary) October 13, 2020
Review: Why and how vaccines work
16 Oct, 2020 | 09:32h | UTCWhy and How Vaccines Work – Cell
Commentary on Twitter
Why and how vaccines work, including how the covid-19 vaccines are positioned, new adjuvants
New @CellCellPress by @VirusesImmunity and @SaadOmer3 https://t.co/ydGfLJh0Uv pic.twitter.com/8niIaMVlAQ— Eric Topol (@EricTopol) October 15, 2020
Life expectancy after bariatric surgery in the Swedish Obese Subjects Study
16 Oct, 2020 | 09:29h | UTCCommentary: Higher average life expectancy after obesity surgery – University of Gothenburg
Commentary on Twitter
This long-term study compared mortality and life expectancy among patients who underwent bariatric surgery or received usual obesity care in the Swedish Obese Subjects study and in persons in the SOS reference study.
— NEJM (@NEJM) October 15, 2020
[Abstract Only] Randomized trial: Upadacitinib vs. Abatacept in rheumatoid arthritis
16 Oct, 2020 | 09:28h | UTCTrial of Upadacitinib or Abatacept in Rheumatoid Arthritis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Rheumatoid Arthritis: When DMARDs Fail, Can JAK Inhibitors Step In? – Physician’s Weekly
Systematic review: Management of colonic diverticulitis
16 Oct, 2020 | 09:25h | UTCManagement of Colonic Diverticulitis – Agency for Healthcare Research and Quality
Full report: Management of Colonic Diverticulitis
Evidence summary: Management of Colonic Diverticulitis
Study: Negative D-dimer safely rules out DVT as a stand-alone test
16 Oct, 2020 | 09:26h | UTCNegative D-dimer safely ruled out DVT as a stand-alone test – Blood Advances
Randomized trial: Effect of sustained smoking cessation counseling and free medication vs. shorter-term counseling and medication advice on smoking abstinence
16 Oct, 2020 | 09:23h | UTCCommentary: Long-term, frequent phone counseling helps cancer patients who smoke quit – eCancer
Review: Evaluation and treatment of patients with hypercortisolism
16 Oct, 2020 | 09:24h | UTCEvaluation and Treatment of Patients With Hypercortisolism: A Review – JAMA Surgery
Updated Cochrane Review shows electronic cigarettes can help people quit smoking
16 Oct, 2020 | 09:21h | UTCUpdated Cochrane Review shows electronic cigarettes can help people quit smoking – Cochrane Library
Original study: Electronic cigarettes for smoking cessation – Cochrane Library
Commentary on Twitter
How do electronic cigarettes compare with other methods of trying to #QuitSmoking? Here's the latest Cochrane evidence from @CochraneTAG: https://t.co/H4Q2n9bYHN #Stoptober. #smoking pic.twitter.com/uIYC7p1sqy
— Cochrane UK (@CochraneUK) October 14, 2020