Daily Archives: June 17, 2020
Randomized Trial: Dexamethasone Reduces Death by Up to One Third in Patients with Severe COVID-19
17 Jun, 2020 | 02:49h | UTCCommentaries: Coronavirus breakthrough: dexamethasone is first drug shown to save lives – Nature AND WHO welcomes preliminary results about dexamethasone use in treating critically ill COVID-19 patients – World Health Organization AND Major study finds common steroid reduces deaths among patients with severe Covid-19 – STAT AND Dexamethasone reduces death in hospitalised patients with severe respiratory complications of COVID-19 – University of Oxford AND Coronavirus: Dexamethasone proves first life-saving drug – BBC
Related Commentary on Twitter
Dexamethasone reduced deaths by 1/3rd in ventilated patients (rate ratio 0.65 [95% CI 0.48 to 0.88]; p=0.0003) and by 1/5th in patients receiving oxygen only (0.80 [0.67 to 0.96]; p=0.0021). No benefit in patients not requiring respiratory support (1.22 [0.86 to 1.75; p=0.14).
— Peter Horby (@PeterHorby) June 16, 2020
Effectiveness of Isolation, Testing, Contact Tracing, and Physical Distancing on Reducing Transmission of SARS-CoV-2 in Different Settings
17 Jun, 2020 | 02:47h | UTC
Coronavirus Antibody Tests Have a Mathematical Pitfall
17 Jun, 2020 | 02:45h | UTCCoronavirus Antibody Tests Have a Mathematical Pitfall – Scientific American
How Deadly is the Coronavirus? Scientists are Close to an Answer
17 Jun, 2020 | 02:44h | UTCHow deadly is the coronavirus? Scientists are close to an answer – Nature
A Visual Guide to the SARS-CoV-2 Coronavirus
17 Jun, 2020 | 02:46h | UTCA Visual Guide to the SARS-CoV-2 Coronavirus – Scientific American
Cohort Study: Ibuprofen Use Not Associated with Worse Outcomes in Covid-19 Patients
17 Jun, 2020 | 02:41h | UTCIbuprofen use and clinical outcomes in COVID-19 patients – Clinical Microbiology and Infection
Related Commentary on Twitter
A new cohort @CMIJournal :
403 COVID-19 patients, Ibuprofen use was NOT associated with worse clinical outcomes, compared to paracetamol or no antipyretic
Ibuprofen use and clinical outcomes in #COVID19 patients.
⛔Median age : 45, younghttps://t.co/Y4WL2UsIDU— Antibiotic Steward? Bassam Ghanem (@ABsteward) June 12, 2020
Age-dependent Effects in the Transmission and Control of COVID-19 Epidemics
17 Jun, 2020 | 02:43h | UTCAge-dependent effects in the transmission and control of COVID-19 epidemics – Nature Medicine
Commentary: People under 20 half as likely to catch Covid-19, study finds – CNN AND Expert reaction to new paper looking at age and COVID-19 susceptibility and severity – Science Media Centre
Temperature, Humidity, and Latitude Analysis to Estimate Potential Spread and Seasonality of COVID-19
17 Jun, 2020 | 02:35h | UTCCommentaries: Hotter Temperatures, Higher Humidity May Reduce Covid-19 Spread – Physician’s Weekly AND Temperature, Humidity, Latitude, and Seasonality of COVID-19 – American College of Cardiology
COVID-19: Pandemic Surgery Guidance
17 Jun, 2020 | 02:39h | UTCCOVID-19: Pandemic surgery guidance – 4open
Commentary: Surgical guidance in the time of COVID-19 – SciencePOD
Systematic Review: Maternal and Neonatal Outcomes Associated With COVID-19 Infection
17 Jun, 2020 | 02:32h | UTCMaternal and Neonatal Outcomes Associated With COVID-19 Infection: A Systematic Review – PLOS One
Systematic Review: Maternal Transmission of SARS‐COV‐2 to the Neonate
17 Jun, 2020 | 02:34h | UTC
The Science Behind the Search for a Covid-19 Vaccine
17 Jun, 2020 | 02:37h | UTCThe Science Behind the Search for a Covid-19 Vaccine – University of Melbourne
Debate on Covid-19 Forecasting: Ioannidis vs. Taleb
17 Jun, 2020 | 02:31h | UTCIntroduction: Ioannidis vs. Taleb on Covid-19
John P.A. Ioannidis: Forecasting for COVID-19 has failed
Nassim Nicholas Taleb: On single point forecasts for fat tailed variables
Randomized Trial: Metabolic Effects of Late Dinner in Healthy Volunteers
17 Jun, 2020 | 02:29h | UTCCommentary: People who eat a late dinner may gain weight – The Endocrine Society
Randomized Trial: Effect of Nonintervention vs. Oral Ibuprofen in Patent Ductus Arteriosus in Preterm Infants
17 Jun, 2020 | 02:30h | UTCCommentary: Trial Finds No Harm in Leaving Preemies’ PDA Alone – MedPage Today (free registration required)
Meta-Analysis: The Risk of Relapse of Depression During Pregnancy After Discontinuation of Antidepressants
17 Jun, 2020 | 02:23h | UTC
Podcast: Post-Op Care and Complications
17 Jun, 2020 | 02:27h | UTC
Research: Vaccination as a Social Contract
17 Jun, 2020 | 02:25h | UTCVaccination as a social contract – Proceedings of the National Academy of Sciences
Antidepressant Efficacy and Side Effect Burden: An Updated Guide for Clinicians
17 Jun, 2020 | 02:23h | UTCAntidepressant efficacy and side effect burden: an updated guide for clinicians – Drugs in Context
Wed June 17 – 10 Stories of The Day!
17 Jun, 2020 | 02:51h | UTC
Commentaries: Coronavirus breakthrough: dexamethasone is first drug shown to save lives – Nature AND WHO welcomes preliminary results about dexamethasone use in treating critically ill COVID-19 patients – World Health Organization AND Major study finds common steroid reduces deaths among patients with severe Covid-19 – STAT AND Dexamethasone reduces death in hospitalised patients with severe respiratory complications of COVID-19 – University of Oxford AND Coronavirus: Dexamethasone proves first life-saving drug – BBC
3 – A Visual Guide to the SARS-CoV-2 Coronavirus – Scientific American
4 – Coronavirus Antibody Tests Have a Mathematical Pitfall – Scientific American
5 – How deadly is the coronavirus? Scientists are close to an answer – Nature
6 – Age-dependent effects in the transmission and control of COVID-19 epidemics – Nature Medicine
Commentary: People under 20 half as likely to catch Covid-19, study finds – CNN AND Expert reaction to new paper looking at age and COVID-19 susceptibility and severity – Science Media Centre
7 – Ibuprofen use and clinical outcomes in COVID-19 patients – Clinical Microbiology and Infection
8 – COVID-19: Pandemic surgery guidance – 4open
Commentary: Surgical guidance in the time of COVID-19 – SciencePOD
9 – The Science Behind the Search for a Covid-19 Vaccine – University of Melbourne
10 –COVID-19 Updates / 17 June 2020 Edition
17 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)