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Daily Archives: October 30, 2019

[Abstract Only] Randomized Trial: Experimental Vaccine Partially Effective at Preventing Latent Tuberculosis from Turning into Active Disease

30 Oct, 2019 | 08:20h | UTC

Final Analysis of a Trial of M72/AS01E Vaccine to Prevent Tuberculosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Vaccine shows promise for preventing active TB disease – Associated Press (free) AND Researchers move closer to new vaccine for killer TB – MedicalXpress (free)

 


Wed October 30 – 10 Stories of The Day!

30 Oct, 2019 | 10:26h | UTC

 

1 – Final Analysis of a Trial of M72/AS01E Vaccine to Prevent Tuberculosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Vaccine shows promise for preventing active TB disease – Associated Press (free) AND Researchers move closer to new vaccine for killer TB – MedicalXpress (free)

 

2 – Efficacy and safety of anti-inflammatory agents for the treatment of major depressive disorder: a systematic review and meta-analysis of randomised controlled trials – Journal of Neurology, Neurosurgery & Psychiatry (free)

Commentaries: Expert reaction to systematic review and meta-analysis of RCTs on anti-inflammatory drugs for depression – Science Media Centre (free) AND Anti-inflammatories can curb major depressive symptoms – OnMedica (free) AND Anti-inflammatory agents can effectively and safely curb major depressive symptoms, study suggests – BMJ (free)

 

3 – Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial – The Lancet Oncology (free)

Commentaries: Reducing infection-related morbidity and mortality in patients with myeloma – The Lancet Oncology (free) AND Abx Prophylaxis Cuts Early Death in Newly Diagnosed Myeloma – MedPage Today (free)

 

4 – Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma – Journal of Clinical Oncology (free)

Commentary: Lenalidomide may delay onset of myeloma-related bone, organ damage – Mayo Clinic (free)

 

5 – Meta-analysis comparing double versus Triple Anti-thrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease – The American Journal of Cardiology (link to abstract – $ for full-text)

Commentary: Meta-analysis: Dual therapy yields less bleeding than triple therapy in AF, CAD – Healio (free registration required)

Related Randomized Trial: Dual Antithrombotic Therapy after PCI in Atrial Fibrillation (free study and commentaries)

Related Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI (free) AND Dual Versus Triple Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention (link to abstract)

 

6 – It’s time to talk about physician burnout and moral injury – The Lancet Psychiatry (free)

Related: Moral Injury and Burnout in Medicine: A Year of Lessons Learned (free Commentaries) AND Consensus Study – Taking Action Against Clinician Burnout: A Systems Approach to Professional Well-Being (free)

 

7 – The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: Global burden of inflammatory bowel disease (free)

 

8 – The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: Pancreatic cancer: a growing burden (free)

 

9 – The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: 27 years of stomach cancer: painting a global picture (free)

 

10 – The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: The global challenge of colorectal cancer (free)

 


Meta-Analysis: Medications with Anti-inflammatory Properties Show Promising Effects in the Treatment of Depression

30 Oct, 2019 | 08:18h | UTC

Efficacy and safety of anti-inflammatory agents for the treatment of major depressive disorder: a systematic review and meta-analysis of randomised controlled trials – Journal of Neurology, Neurosurgery & Psychiatry (free)

Commentaries: Expert reaction to systematic review and meta-analysis of RCTs on anti-inflammatory drugs for depression – Science Media Centre (free) AND Anti-inflammatories can curb major depressive symptoms – OnMedica (free) AND Anti-inflammatory agents can effectively and safely curb major depressive symptoms, study suggests – BMJ (free)

 


Randomized Trial: Levofloxacin Prophylaxis Reduces Early Deaths in Patients with Newly Diagnosed Myeloma

30 Oct, 2019 | 08:17h | UTC

Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial – The Lancet Oncology (free)

Commentaries: Reducing infection-related morbidity and mortality in patients with myeloma – The Lancet Oncology (free) AND Abx Prophylaxis Cuts Early Death in Newly Diagnosed Myeloma – MedPage Today (free)

 


Randomized Trial: Treatment vs. Observation in Smoldering Multiple Myeloma

30 Oct, 2019 | 08:15h | UTC

Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma – Journal of Clinical Oncology (free)

Commentary: Lenalidomide may delay onset of myeloma-related bone, organ damage – Mayo Clinic (free)

 


[Abstract Only] Meta-analysis: Double Anti-thrombotic Therapy Safer than Triple Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease

30 Oct, 2019 | 08:14h | UTC

Meta-analysis comparing double versus Triple Anti-thrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease – The American Journal of Cardiology (link to abstract – $ for full-text)

Commentary: Meta-analysis: Dual therapy yields less bleeding than triple therapy in AF, CAD – Healio (free registration required)

Related Randomized Trial: Dual Antithrombotic Therapy after PCI in Atrial Fibrillation (free study and commentaries)

Related Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI (free) AND Dual Versus Triple Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention (link to abstract)

 


Opinion: It’s Time to Talk About Physician Burnout and Moral Injury

30 Oct, 2019 | 08:12h | UTC

It’s time to talk about physician burnout and moral injury – The Lancet Psychiatry (free)

Related: Moral Injury and Burnout in Medicine: A Year of Lessons Learned (free Commentaries) AND Consensus Study – Taking Action Against Clinician Burnout: A Systems Approach to Professional Well-Being (free)

 


The Global Burden of Pancreatic Cancer

30 Oct, 2019 | 07:59h | UTC

The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: Pancreatic cancer: a growing burden (free)

 

Related Commentary on Twitter

 


The Global Burden of Colorectal Cancer

30 Oct, 2019 | 07:55h | UTC

The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: The global challenge of colorectal cancer (free)

 

Related Commentary on Twitter

 


The Global Burden of Inflammatory Bowel Disease

30 Oct, 2019 | 08:01h | UTC

The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: Global burden of inflammatory bowel disease (free)

 

Related Commentary on Twitter

 


The Global Burden of Gastric Cancer

30 Oct, 2019 | 07:57h | UTC

The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: 27 years of stomach cancer: painting a global picture (free)

 

Related Commentary on Twitter

 


Treatment for Acute Pain: An Evidence Map

30 Oct, 2019 | 07:50h | UTC

Treatment for Acute Pain: An Evidence Map – Agency for Healthcare Research and Quality (free PDF)

See also: Summary (free)

 


Infographic: Global Trends in Type 2 Diabetes, 2007-2017

30 Oct, 2019 | 07:52h | UTC

Global Trends in Type 2 Diabetes, 2007-2017 – JAMA (free for a limited period)

 

Related Commentary on Twitter

 


Hypertension in Patients on Dialysis: Diagnosis, Mechanisms, and Management

30 Oct, 2019 | 07:49h | UTC

Hypertension in patients on dialysis: diagnosis, mechanisms, and management – Brazilian Journal of Nephrology (free)

 


Congenital Chagas Disease: Updated Recommendations

30 Oct, 2019 | 07:44h | UTC

Congenital Chagas disease: Updated recommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing age, and pregnant women – PLOS Neglected Tropical Diseases (free)

 


Report on Advances for Pediatricians in 2018

30 Oct, 2019 | 07:51h | UTC

Report on advances for pediatricians in 2018: allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroenterology, infectious diseases, neonatology, nutrition, respiratory tract disorders and surgery – Italian Journal of Pediatrics (free)

 


Systematic Review: Botulinum Toxin Type A in the Treatment of Lower Limb Spasticity in Children with Cerebral Palsy

30 Oct, 2019 | 07:42h | UTC

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy – Cochrane Library (free)

Summary: Botulinum toxin type A injections for the treatment of lower limb spasticity in cerebral palsy – Cochrane Library (free)

 


Together We Stand, Divided We Fall: A Multidisciplinary Approach in Complicated Acute Pancreatitis

30 Oct, 2019 | 07:46h | UTC

Together We Stand, Divided We Fall: A Multidisciplinary Approach in Complicated Acute Pancreatitis – Journal of Clinical Medicine (free)

Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)

 


Review: Management of Peripartum Intra‐abdominal Hypertension and Abdominal Compartment Syndrome

30 Oct, 2019 | 07:39h | UTC

Management of peripartum intra‐abdominal hypertension and abdominal compartment syndrome – Acta Obstetricia et Gynecologica Scandinavica (free)

 


Harnessing Emerging Information Technology for Bundled Payment Care Using a Value-Driven Framework

30 Oct, 2019 | 07:41h | UTC

Harnessing Emerging Information Technology for Bundled Payment Care Using a Value-Driven Framework – NEJM Catalyst (free)

 


[Abstract Only] Randomized Trial: Perioperative Corticosteroids Reduce Dysphagia Following Surgical Procedures Involving the Anterior Cervical Spine

30 Oct, 2019 | 07:40h | UTC

The Effects of Perioperative Corticosteroids on Dysphagia Following Surgical Procedures Involving the Anterior Cervical Spine: A Prospective, Randomized, Controlled, Double-Blinded Clinical Trial – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts

 


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