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Daily Archives: September 19, 2019

ATS Research Statement: Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor–related Pneumonitis

19 Sep, 2019 | 07:59h | UTC

Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor–related Pneumonitis. An Official American Thoracic Society Research Statement – American Journal of Respiratory and Critical Care Medicine (free)

Related: Immune Checkpoint Inhibitor Toxicities (guidelines and reviews on the subject)

 


Thu September 19 – 10 Stories of The Day!

19 Sep, 2019 | 10:50h | UTC

 

1 – Consensus Statement: Healthy Beverage Consumption in Early Childhood: Recommendations from Key National Health and Nutrition Organizations – Health Eating Research (free PDF)

News Releases: 4 groups issue consensus report on healthy beverages for 0- to 5-year-olds – American Academy of Pediatrics (free) AND Leading Health Organizations Support First-Ever Consensus Recommendations to Encourage Young Children’s Consumption of Healthy Drinks – American Heart Association (free)  

Commentaries: What Should Young Children Drink? Mostly Milk and Water, Scientists Say – The New York Times (10 articles per month are free) AND Parents Should Limit Kids’ Juice Consumption, Guidelines Say – U.S. News (free)

See also: Health Kids, Health Drinks (free resources for the public)

Related: AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free)

 

2 – Global Preparedness Monitoring Board. A world at risk: annual report on global preparedness for health emergencies – World Health Organization (free PDF)

See also: Executive Summary (free PDF) AND Global Preparedness Monitoring Board Website (free resources)

Commentaries: Experts detail global pandemic readiness gaps, offer steps – CIDRAP (free) AND World at risk of pandemics that could kill millions, panel warns – Reuters (free) AND Experts warn world ‘grossly unprepared’ for future pandemics – The Guardian (free)

 

3 – Polypill for Cardiovascular Disease Prevention in an Underserved Population – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Polypill Drops BP, LDL Cholesterol in a Disadvantaged US Population – TCTMD (free) AND One daily combo pill helps lower heart disease risk in study of underserved patients – American Heart Association (free) AND Fixed Dose Combination Polypill Can Reduce Barriers to Cardiovascular Care – MedicalResearch.com (free) AND One pill with four drugs may lower heart risks in poor population – Reuters (free) AND All-in-One Pill Reduces Blood Pressure, Cholesterol Levels in U.S. Study – Vanderbilt University Medical Center (free)

Related Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases (link to abstract and commentaries)

See also: Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) AND Perspective: The Polypill and the Long Journey to Major Impact (opinion and reviews on the subject) AND Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care (free commentaries)

 

4 – C-section babies are missing key microbes – Nature News (free)

Original Study: Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth – Nature (link to abstract – $ for full-text)

Other Commentaries: Babies’ gut bacteria affected by delivery method, Baby Biome project shows – Wellcome Sanger Institute (free) AND Babies born by C-section have more potentially infectious bacteria in their guts – ScienceNews (free)

“UK study provides the best evidence yet that the way infants are born can alter their microbiomes — but the health effects are unclear.”

 

5 – Less is more in critical care is supported by evidence-based medicine – Intensive Care Medicine (free for a limited period)

Related: Less is More: Ten Reasons for Considering to Discontinue Unproven Interventions (free commentaries)

 

6 – Less is more in nutrition: critically ill patients are starving but not hungry – Intensive Care Medicine (free)

 

7 – Alex Nowbar’s journal review, 18 September 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

8 – National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys – Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentaries: HCV-Infected Donor Kidneys Offer Good Short-Term Graft Function – Renal & Urology News (free) AND Hepatitis C-infected kidneys function as well as others after transplant, study says – CNN (free) AND Hepatitis C-Infected Kidneys Function Similar to Uninfected Organs One Year After Transplant – Penn Medicine (free) AND Kidney Transplants from Donors with HCV Safe and Functional 1 Year Post-Transplantation – American Society of Nephrology (ASN) (free)

Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries)

 

9 – Testing for Meningitis in Febrile Well-Appearing Young Infants With a Positive Urinalysis – Pediatrics (link to abstract – $ for full-text)

Commentary: Could meningitis testing be omitted in febrile infants with positive UTI? – Univadis (free registration required)

 

10 – Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor–related Pneumonitis. An Official American Thoracic Society Research Statement – American Journal of Respiratory and Critical Care Medicine (free)

Related: Immune Checkpoint Inhibitor Toxicities (guidelines and reviews on the subject)

 


Consensus Statement: Healthy Beverage Consumption in Early Childhood: Recommendations from Key Health and Nutrition Organizations

19 Sep, 2019 | 10:28h | UTC

Consensus Statement: Healthy Beverage Consumption in Early Childhood: Recommendations from Key National Health and Nutrition Organizations – Health Eating Research (free PDF)

News Releases: 4 groups issue consensus report on healthy beverages for 0- to 5-year-olds – American Academy of Pediatrics (free) AND Leading Health Organizations Support First-Ever Consensus Recommendations to Encourage Young Children’s Consumption of Healthy Drinks – American Heart Association (free)

Commentaries: What Should Young Children Drink? Mostly Milk and Water, Scientists Say – The New York Times (10 articles per month are free) AND Parents Should Limit Kids’ Juice Consumption, Guidelines Say – U.S. News (free)

See also: Health Kids, Health Drinks (free resources for the public)

Related: AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free)

 


A World at Risk: Annual Report on Global Preparedness for Health Emergencies

19 Sep, 2019 | 10:27h | UTC

Global Preparedness Monitoring Board. A world at risk: annual report on global preparedness for health emergencies – World Health Organization (free PDF)

See also: Executive Summary (free PDF) AND Global Preparedness Monitoring Board Website (free resources)

Commentaries: Experts detail global pandemic readiness gaps, offer steps – CIDRAP (free) AND World at risk of pandemics that could kill millions, panel warns – Reuters (free) AND Experts warn world ‘grossly unprepared’ for future pandemics – The Guardian (free)

 


Less is More in Critical Care is Supported by Evidence-based Medicine

19 Sep, 2019 | 08:15h | UTC

Less is more in critical care is supported by evidence-based medicine – Intensive Care Medicine (free for a limited period)

Related: Less is More: Ten Reasons for Considering to Discontinue Unproven Interventions (free commentaries)

 


[Abstract Only] Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population

19 Sep, 2019 | 08:19h | UTC

Polypill for Cardiovascular Disease Prevention in an Underserved Population – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Polypill Drops BP, LDL Cholesterol in a Disadvantaged US Population – TCTMD (free) AND One daily combo pill helps lower heart disease risk in study of underserved patients – American Heart Association (free) AND Fixed Dose Combination Polypill Can Reduce Barriers to Cardiovascular Care – MedicalResearch.com (free) AND One pill with four drugs may lower heart risks in poor population – Reuters (free) AND All-in-One Pill Reduces Blood Pressure, Cholesterol Levels in U.S. Study – Vanderbilt University Medical Center (free)

Related Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases (link to abstract and commentaries)

See also: Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) AND Perspective: The Polypill and the Long Journey to Major Impact (opinion and reviews on the subject) AND Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care (free commentaries)

 


Alex Nowbar’s journal review—18 September 2019

19 Sep, 2019 | 08:11h | UTC

Alex Nowbar’s journal review, 18 September 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


[Abstract Only] Study: C-section Babies are Missing Key Microbes

19 Sep, 2019 | 08:17h | UTC

C-section babies are missing key microbes – Nature News (free)

Original Study: Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth – Nature (link to abstract – $ for full-text)

Other Commentaries: Babies’ gut bacteria affected by delivery method, Baby Biome project shows – Wellcome Sanger Institute (free) AND Babies born by C-section have more potentially infectious bacteria in their guts – ScienceNews (free)

“UK study provides the best evidence yet that the way infants are born can alter their microbiomes — but the health effects are unclear.”

 


Less is More in Nutrition: Critically ill Patients are Starving but not Hungry

19 Sep, 2019 | 08:13h | UTC

Less is more in nutrition: critically ill patients are starving but not hungry – Intensive Care Medicine (free)

 


[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis

19 Sep, 2019 | 08:00h | UTC

Testing for Meningitis in Febrile Well-Appearing Young Infants With a Positive Urinalysis – Pediatrics (link to abstract – $ for full-text)

Commentary: Could meningitis testing be omitted in febrile infants with positive UTI? – Univadis (free registration required)

 


[Abstract Only] Randomized Trial: GLP-1 Receptor Agonist Superior to SGLT2 Inhibitor for Glucose Control and Weight Loss in Patients with Type 2 Diabetes Uncontrolled on Metformin Therapy

19 Sep, 2019 | 07:51h | UTC

Efficacy and safety of once-weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial – The Lancet Endocrinology & Metabolism (link to abstract – $ for full-text)

Commentary: Add-On Diabetes Treatment: Semaglutide Improves HbA1c Better Than Canagliflozin – NEJM Journal Watch (free)

 


[Abstract Only] Study: Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys

19 Sep, 2019 | 08:10h | UTC

National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys – Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentaries: HCV-Infected Donor Kidneys Offer Good Short-Term Graft Function – Renal & Urology News (free) AND Hepatitis C-infected kidneys function as well as others after transplant, study says – CNN (free) AND Hepatitis C-Infected Kidneys Function Similar to Uninfected Organs One Year After Transplant – Penn Medicine (free) AND Kidney Transplants from Donors with HCV Safe and Functional 1 Year Post-Transplantation – American Society of Nephrology (ASN) (free)

Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries)

 


[Abstract Only] Randomized Trial: Early Combination Therapy Provides Greater and Durable Long-term Glucose Control in Patients with Newly Diagnosed Type 2 Diabetes

19 Sep, 2019 | 07:49h | UTC

Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Two-drug combo more effective at lowering blood sugar in diabetes patients – UPI (free) AND New study shows long-term durability of early combination therapy in patients newly diagnosed with type 2 diabetes – MedicalXpress (free)

 


Nutrition in Gastrointestinal Disease: Liver, Pancreatic, and Inflammatory Bowel Disease

19 Sep, 2019 | 07:46h | UTC

Nutrition in Gastrointestinal Disease: Liver, Pancreatic, and Inflammatory Bowel Disease – Journal of Clinical Medicine (free)

 


Perspective: Why is it so Hard to Stop People Dying from Snakebite?

19 Sep, 2019 | 07:42h | UTC

Why is it so hard to stop people dying from snakebite? – Mosaic (free)

Related: WHO’s Snakebite Envenoming Strategy for Prevention and Control (free resources)

Source: STAT Newsletter

 


India Announces Widespread Ban of E-Cigarettes

19 Sep, 2019 | 07:48h | UTC

India Announces Widespread Ban Of E-Cigarettes – NPR (free)

See also: India e-cigarettes: Ban announced to prevent youth ‘epidemic’ – BBC (free) AND India bans e-cigarettes as global backlash at vaping gathers pace – Reuters (free)

 


Study: The Rising Burden of Non-communicable Diseases in Sub-Saharan Africa

19 Sep, 2019 | 07:45h | UTC

Burden of non-communicable diseases in sub-Saharan Africa, 1990–2017: results from the Global Burden of Disease Study 2017 – The Lancet Global Health (free)

Commentary: The rising burden of non-communicable diseases in sub-Saharan Africa – The Lancet Global Health (free)

 


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