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Daily Archives: March 23, 2018

Selected Articles from the Annual Update in Intensive Care and Emergency Medicine 2018

23 Mar, 2018 | 02:50h | UTC

Selected Articles from the Annual Update in Intensive Care and Emergency Medicine 2018 – BMC (free) (via @CritCareReviews)

 


Guideline: Tracheotomy in the intensive care unit

23 Mar, 2018 | 02:48h | UTC

Tracheotomy in the intensive care unit: guidelines from a French expert panel – Annals of Intensive Care (free)

 


Systematic Review: Are shorter courses of systemic steroids as effective as conventional longer courses in the treatment of patients with flare-ups of COPD?

23 Mar, 2018 | 02:50h | UTC

Are shorter courses of systemic steroids as effective as conventional longer courses in the treatment of patients with flare-ups of COPD? – Cochrane Library (free)

“Information from a new large study has increased our confidence that five days of oral corticosteroids is likely to be sufficient for treatment of adults with acute exacerbations of COPD”.

 


Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

23 Mar, 2018 | 02:51h | UTC

Guideline: Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism – National Institute for Health and Care Excellence (NICE) (free)

 


For hypertension and diabetes, lower treatment targets not necessarily better

23 Mar, 2018 | 02:47h | UTC

For hypertension and diabetes, lower treatment targets not necessarily better – American Family Physician Community Blog (free)

Related: AAFP Decides to Not Endorse AHA/ACC Hypertension Guideline (free) AND ACC/AHA Hypertension Guideline: What Is New? What Do We Do? – American Family Physician (free) AND Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)

 


Cardiology World Erupts Into Controversy Over Change In Major Clinical Trial

23 Mar, 2018 | 02:49h | UTC

Cardiology World Erupts Into Controversy Over Change In Major Clinical Trial – Cardiobrief (free)

Related Article: Moving the Goalposts Into Unblinded Territory – Circulation: Cardiovascular Quality and Outcomes (free)

 


Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation

23 Mar, 2018 | 02:46h | UTC

The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation – European Heart Journal (free for a limited period)

News release: New EHRA Practical Guide on non-vitamin K antagonist oral anticoagulants launched (free)

 


Violence and Mental Health: Opportunities for Prevention and Early Detection

23 Mar, 2018 | 02:45h | UTC

Report: Violence and Mental Health: Opportunities for Prevention and Early Detection – National Academies Press (free PDF)

 


New Tool: Sustainable Development Goal (SDG) Tracker

23 Mar, 2018 | 02:47h | UTC

New Tool: Sustainable Development Goal (SDG) Tracker – Our World in Data (free)

Commentary: The U.N. Set 17 Goals To Make The World A Better Place. How’s It Doing? – NPR (free)

“The United Nations Sustainable Development Goals (SDGs) are targets for global development adopted in September 2015, set to be achieved by 2030. Here we present data across all available indicators from the Our World in Data database tracking progress towards these goals around the world”.

 


Breast Implant-Associated Anaplastic Large Cell Lymphoma

23 Mar, 2018 | 02:42h | UTC

FDA In Brief: FDA updates public information about known risk of lymphoma from breast implants (free) AND Breast Implant-Associated Anaplastic Large Cell Lymphoma – FDA Update (free)

Commentaries: More Cases Are Reported of Unusual Cancer Linked to Breast Implants – The New York Times (10 articles per month are free) AND Implant-Related Lymphoma Cases Rise – More than 400 cases reported to FDA – MedPage Today (free)

“Some 400 to 500 women worldwide have an unusual type of lymphoma linked to breast implants with textured surfaces. Experts say women considering implants should be told”. (via @NYTHealth see Tweet)

 


When antibiotics turn toxic

23 Mar, 2018 | 02:43h | UTC

When antibiotics turn toxic – Nature News (free)

“Commonly prescribed drugs called fluoroquinolones cause rare, disabling side effects. Researchers are struggling to work out why”.

 


Associations of Monounsaturated Fatty Acids From Plant and Animal Sources With Total and Cardiovascular Mortality Risk

23 Mar, 2018 | 02:44h | UTC

Associations of Monounsaturated Fatty Acids From Plant and Animal Sources With Total and Cardiovascular Mortality Risk – Circulation (link to abstract – presented at the American Heart Association’s Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2018)

Commentaries: Mono-unsaturated fats from plants, not animals may reduce risk of death from heart disease and other causes – AHA / ASA Newsroom (free) AND These plant-based fats could help you live longer – Medical News Today (free)

 


Imaging is the only way to diagnose blood clots in pregnancy

23 Mar, 2018 | 02:39h | UTC

The DiPEP (Diagnosis of PE in Pregnancy) biomarker study: An observational cohort study augmented with additional cases to determine the diagnostic utility of biomarkers for suspected venous thromboembolism during pregnancy and puerperium – British Journal of Haematology (free)

Commentary: Imaging is the only way to diagnose blood clots in pregnancy – NIHR Signal (free)

“No blood test can accurately tell if a pregnant or recently pregnant woman has a blood clot. All pregnant women with a suspected clot should continue to have imaging investigations” (via @NIHR_DC  see Tweet)

 


A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis

23 Mar, 2018 | 02:43h | UTC

A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis – New England Journal of Medicine (free)

Commentaries: Efficacy of High-Flow O2 Tx Test Outside ICU for Infants With Bronchiolitis? – MPR (free) AND High-flow O2 therapy feasible for infants with bronchiolitis – MedicalXpress (free) AND High-Flow Oxygen Improves Infant Bronchiolitis Outcomes – MedPage Today (free)

 


Preventing physician suicide

23 Mar, 2018 | 02:38h | UTC

Preventing physician suicide – ACP Hospitalist (free)

Related: What I’ve learned from my tally of 757 doctor suicides – The Washington Post (free) AND Why are doctors killing themselves? – MJA InSight (free) AND Why are doctors plagued by depression and suicide? A crisis comes into focus – STAT (free) AND Protecting interns and other physicians from depression and suicide – STAT (free)

 


Low Back Pain – New Series from The Lancet Journals

23 Mar, 2018 | 02:41h | UTC

Low Back Pain – New Series from The Lancet Journals

– Homepage and Executive Summary (free)

– Article 1: What low back pain is and why we need to pay attention (free registration required)

– Article 2: Prevention and treatment of low back pain: evidence, challenges, and promising directions (free registration required)

– Invited Commentary: Low back pain: a major global challenge (free registration required)

– Viewpoint: Low back pain: a call for action (free registration required)

Commentaries: Low Back Pain Affects 540 Million People Worldwide, but Too Many Patients Receive the Wrong Care – University of Warwick, via NewsWise (free) AND Lower back pain being treated badly on a global scale, study says – The Guardian (free)

 


Causes of death among children aged 5–14 years in the WHO European Region

23 Mar, 2018 | 02:40h | UTC

Causes of death among children aged 5–14 years in the WHO European Region: a systematic analysis for the Global Burden of Disease Study 2016 – The Lancet Child & Adolescent Health (free)

Invited commentary: Mortality in older children and adolescents: the forgotten ones (free)

Graphic 1: Top 25 causes of death in the WHO European Region, age 5–9 years, both sexes, 1990 and 2016 (free)

Graphic 2: Top 25 causes of death in the WHO European Region, age 10–14 years, both sexes, 1990 and 2016 (free)

 


Research: Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms

23 Mar, 2018 | 02:37h | UTC

Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Invited commentary: Rethinking the Approach to Managing Postmenopausal Vulvovaginal Symptoms (free)

Author interview: Efficacy of Vaginal Estradiol or Moisturizer vs Placebo for Postmenopausal Vulvovaginal Symptoms (free)

Commentary: Vaginal Estradiol Offers Little Help for Postmenopausal Symptoms – Moisturizer no better than placebo gel, either – MedPage Today (free registration required)

 


Are we prepared for the looming epidemic threat?

23 Mar, 2018 | 02:36h | UTC

Are we prepared for the looming epidemic threat? – The Guardian (free) (via @Onisillos)

Related: The World Is Not Ready for the Next Pandemic – TIME cover story AND The World Is Completely Unprepared for a Global Pandemic – Harvard Business Review (free) AND Seven reasons we’re at more risk than ever of a global pandemic – CNN (free) AND Video: Pandemics – a worrying global public health threat (free)

 


The Sustainable Development Goals – A global, transdisciplinary vision for the future

23 Mar, 2018 | 02:38h | UTC

Free Online Course (small fee if applying for certificate). Starts March 26, 2018. The Sustainable Development Goals – A global, transdisciplinary vision for the future – University of Copenhagen and Coursera

 


Gender differences in the associations between age trends of social media interaction and well-being among 10-15 year olds

23 Mar, 2018 | 02:35h | UTC

Gender differences in the associations between age trends of social media interaction and well-being among 10-15 year olds in the UK – BMC Public Health (free)

Commentaries: Mental health risks to girls who spend more than an hour a day on social media – new study  – The Conversation (free) AND How much is too much? Does increasing use of social media having a damaging effect on young girls? – BMC Series Blog (free) AND Social Media May Be More Harmful To Girls Than Boys, Study Finds – Forbes (free)

See also a recent Pediatrics supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn (free supplement) and related texts on Social Media and Mental Health (free articles and commentaries)

 


Expert consensus on arrhythmias and cognitive function

23 Mar, 2018 | 02:36h | UTC

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: what is the best practice? (free)

Commentary: New Expert Statement on Arrhythmias and Cognitive Function – Medscape (free registration required)

 


Diastolic blood pressure and adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension

23 Mar, 2018 | 02:34h | UTC

Diastolic Blood Pressure and Adverse Outcomes in the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) Trial – Journal of the American Heart Association (free for a limited period)

“DBP values ≥90 and <60 mm Hg are associated with a significant risk of adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension”.

 


Fri, March 23 – 10 Stories of The Day!

23 Mar, 2018 | 02:04h | UTC

 

1 – Guideline: Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism – National Institute for Health and Care Excellence (NICE) (free)

 

2 – New Tool: Sustainable Development Goal (SDG) Tracker – Our World in Data (free)

Commentary: The U.N. Set 17 Goals To Make The World A Better Place. How’s It Doing? – NPR (free)

“The United Nations Sustainable Development Goals (SDGs) are targets for global development adopted in September 2015, set to be achieved by 2030. Here we present data across all available indicators from the Our World in Data database tracking progress towards these goals around the world”.

 

3 – When antibiotics turn toxic – Nature News (free)

“Commonly prescribed drugs called fluoroquinolones cause rare, disabling side effects. Researchers are struggling to work out why”.

 

4 – Associations of Monounsaturated Fatty Acids From Plant and Animal Sources With Total and Cardiovascular Mortality Risk – Circulation (link to abstract – presented at the American Heart Association’s Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2018)

Commentaries: Mono-unsaturated fats from plants, not animals may reduce risk of death from heart disease and other causes – AHA / ASA Newsroom (free) AND These plant-based fats could help you live longer – Medical News Today (free)

 

5 – Report: Violence and Mental Health: Opportunities for Prevention and Early Detection – National Academies Press (free PDF)

 

6 – A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis – New England Journal of Medicine (free)

Commentaries: Efficacy of High-Flow O2 Tx Test Outside ICU for Infants With Bronchiolitis? – MPR (free) AND High-flow O2 therapy feasible for infants with bronchiolitis – MedicalXpress (free) AND High-Flow Oxygen Improves Infant Bronchiolitis Outcomes – MedPage Today (free)

 

7 – FDA In Brief: FDA updates public information about known risk of lymphoma from breast implants (free) AND Breast Implant-Associated Anaplastic Large Cell Lymphoma – FDA Update (free)

Commentaries: More Cases Are Reported of Unusual Cancer Linked to Breast Implants – The New York Times (10 articles per month are free) AND Implant-Related Lymphoma Cases Rise – More than 400 cases reported to FDA – MedPage Today (free)

Some 400 to 500 women worldwide have an unusual type of lymphoma linked to breast implants with textured surfaces. Experts say women considering implants should be told”. (via @NYTHealth see Tweet)

 

8 – Viewpoint: The Proposal to Lower P Value Thresholds to .005 – JAMA (free) (via @VinayPrasad82 see Tweet)

Related: What a nerdy debate about p-values shows about science — and how to fix it – VOX (free) AND Big names in statistics want to shake up much-maligned P value – Nature News (free) AND ‘One-size-fits-all’ threshold for P values under fire – Nature News (free) AND Statisticians issue warning over misuse of P values – Nature News (free) AND Understanding common misconceptions about p-values – The 20% Statistician (free) AND Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations – European Journal of Epidemiology(free)

 

9 – Effect of tai chi versus aerobic exercise for fibromyalgia: comparative effectiveness randomized controlled trial – The BMJ (free)

Commentaries: Time to rethink exercise for fibromyalgia care – The BMJ Opinion (free) AND The unintended consequences of tai chi for fibromyalgia – The BMJ Opinion (free) AND Tai chi may be as effective for fibromyalgia as standard exercise – NHS Choices (free) AND Tai chi at least as beneficial as aerobic exercise for fibromyalgia – OnMedica (free)

 

10 – Efficacy of a single-dose regimen of inactivated whole-cell oral cholera vaccine: results from 2 years of follow-up of a randomised trial – The Lancet Infectious Diseases (free)

Invited commentary: Cholera control: one dose at a time (free)

“Our results indicate that when such emergencies occur in populations with endemic cholera, the challenges of successfully completing a two-dose regimen should not deter deployment of OCV, because older children and adults will be protected for at least 2 years by a single dose”. (via @Onisillos see Tweet)

 


Systematic Review: Oral vitamin B12 compared with intramuscular vitamin B12

23 Mar, 2018 | 02:32h | UTC

Oral vitamin B12 compared with intramuscular vitamin B12 for vitamin B12 deficiency – Cochrane Library (free)

Commentary: Oral vs. Intramuscular Vitamin B12: Efficacy, Safety Compared – MPR (free)

 


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