Daily Archives: December 28, 2017

“A formidable group of oncologists has come together with the joint aim of improving access, affordability, and sustainability (value) of cancer therapies”.

Original abstract: A prospective international randomized phase II study evaluating the food effect on the pharmacokinetics (PK) and pharmacodynamics (PD) of abiraterone acetate (AA) in men with castration-resistant prostate cancer (CRPC) (free) AND Commentary: A group of cancer doctors discovered a way to slash the cost of expensive pills by up to 75%, but they’ve hit a wall – Business Insider (free)

Related Website (news section): Value in Cancer Care Consortium (free resources)

Research: Post-Exposure Prophylaxis with Doxycycline to Prevent Sexually Transmitted Infections in Men Who Have Sex With Men

28 Dec, 2017 | 17:26h | UTC

Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Commentaries: Post Exposure Doxycycline in PReP Users May Reduce Risk of Syphilis and Chlamydiae – MedicalResearch (free) AND Doxycycline After Condomless Sex Lowers STI Risk in High-Risk Men – Physician’s First Watch (free) AND Antibiotics could dramatically reduce STIs, study says, raising tough new questions – STAT (free) AND Antibiotics could ‘dramatically reduce’ STIs, STAT says, though findings apply to small group of men – HealthNewsReview (free) AND

Opinion: Are Hospital Readmission Penalties a Good Idea?

28 Dec, 2017 | 17:23h | UTC

The data are in, but debate rages: Are hospital readmission penalties a good idea? – STAT (free)

Research: Association of the Hospital Readmissions Reduction Program With Outcomes in Heart Failure

28 Dec, 2017 | 17:22h | UTC

Association of the Hospital Readmissions Reduction Program Implementation With Readmission and Mortality Outcomes in Heart Failure – JAMA (link to abstract – $ for full-text)

Commentaries: To Fix the Hospital Readmissions Program, Prioritize What Matters – JAMA Forum (free) AND Readmissions reduction program linked to increased mortality for heart failure patients – Cardiovascular Business (free) AND Going the Wrong Way: ACA’s Readmission Reduction Program Linked To Increased Heart Failure Deaths – MedicalResearch (free) AND Hospital quality-control program tied to rise in heart failure deaths – Reuters (free)

Research: Exposure to Magnetic Field Non-Ionizing Radiation and the Risk of Miscarriage

28 Dec, 2017 | 17:19h | UTC

Exposure to Magnetic Field Non-Ionizing Radiation and the Risk of Miscarriage: A Prospective Cohort Study – Scientific Reports (free)

Commentary: Health risks linked to electromagnetic field exposure – Kaiser Permanente, via ScienceDaily (free)

Report: Strategies to Limit Sugar-Sweetened Beverage Consumption in Young Children

28 Dec, 2017 | 17:20h | UTC

Strategies to Limit Sugar-Sweetened Beverage Consumption in Young Children – The National Academies Press (free PDF)

Meta-Analysis: Association of Age-Related Hearing Loss With Cognitive Function

28 Dec, 2017 | 17:18h | UTC

Association of Age-Related Hearing Loss With Cognitive Function, Cognitive Impairment, and Dementia: A Systematic Review and Meta-analysis – JAMA Otolaryngology-Head & Neck Surgery (link to abstract – $ for full-text)

Commentaries: Hearing loss may be a risk factor for dementia – Reuters (free) AND As hearing fades with age, dementia risk may rise – MedicalXpress (free)

Review: Inpatient Management of Diabetic Foot Infections

28 Dec, 2017 | 17:16h | UTC

Inpatient Management of Diabetic Foot Infections: A Review of the Guidelines for Hospitalists – Journal of Hospital Medicine (free PDF)

Treating Anxiety in Children

28 Dec, 2017 | 17:08h | UTC

Treating Anxiety in Children – The New York Times (10 articles per month are free)

Fewer Large Babies are Born to Pregnant Woman With Type 1 Diabetes With Continuous Glucose Monitoring

28 Dec, 2017 | 17:13h | UTC

Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously – NIHR Signal (free)

Original article and commentary: Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial – The Lancet (free) AND Commentary: Continuous glucose monitoring in pregnant women with type 1 diabetes (free)

Research: Small Increases in Complications When Knee Replacement Done as Outpatient Procedure

28 Dec, 2017 | 17:06h | UTC

Outpatient Total Knee Arthroplasty Is Associated with Higher Risk of Perioperative Complications – The Journal of Bone & Joint Surgery (free)

Commentaries: Small increases in complications when knee replacement done as outpatient procedure – Wolters Kluwer Health, Via EurekAlert (free) AND More Data on Outpatient vs Inpatient Joint Replacement – OrthoBuzz (free) AND Outpatient Knee Replacement Complications: How Important Are They? – OrthoBuzz (free)

Childhood Obesity Climbing with Media Use, European Doctors Warn

28 Dec, 2017 | 17:08h | UTC

Childhood obesity climbing with media use, European doctors warn – Reuters (free)

Clinical Trial Transparency: A Guide for Policymakers

28 Dec, 2017 | 17:15h | UTC

Clinical Trial Transparency: A Guide for Policymakers – by Transparency International Pharmaceuticals & Healthcare (PHP), TranspariMED, Cochrane, and Collaboration for Research Integrity and Transparency (CRIT) (free PDF)

Press Release: O pacity over clinical trials of medical treatments putting patients at risk – Transparency International (free)

Source: Rules on reporting trials must be better enforced, say health integrity groups – The BMJ News ($)

Research: Physiotherapy Breathing Retraining for Asthma

28 Dec, 2017 | 17:05h | UTC

Physiotherapy breathing retraining for asthma: a randomised controlled trial – The Lancet Respiratory Medicine (free)

Commentaries: Remote or in-person breathing retraining for uncontrolled asthma symptoms – The Lancet Respiratory Medicine (free) AND Self-taught Breathing Retraining Helps Asthma Patients – Medscape (free registration required)

Top Ten Things to Know: Defining Quality in Cardiovascular Imaging (free PDF)

Commentary: “Quality” in Cardiovascular Imaging – Getting to the Heart of the Meaning (free)

Guideline: Treating Axial Spondyloarthritis and Peripheral Spondyloarthritis

Lying on One’s Side in Labour With an Epidural is Safe and Leads to More Spontaneous Births

Research: Rifampicin of No Benefit for Staphylococcus Aureus Bacteraemia

Research: Healthy Diet, Happy Child?

Guideline: Interventions to Address Sexual Problems in People With Cancer

Projections of Temperature-Related Excess Mortality Under Climate Change Scenarios

Cardiorespiratory Health Effects of Particulate Ambient Air Pollution Exposure in Low-Income and Middle-Income Countries

Tackling the High Cost of Cancer Care