Urology
Meta-Analysis: MRI plus Targeted Biopsy vs. Systematic Biopsy Alone for the Diagnosis of Prostate Cancer
8 Aug, 2019 | 08:13h | UTCCommentaries: The Evolving Paradigm of Prostate Cancer Screening – JAMA Network Open (free) AND MRIs Improve Targeting of Biopsies for Prostate Cancer Diagnosis – MedicalResearch.com (free)
Related Cochrane Review: MRI Pathway vs. Systematic Biopsy for Detecting Prostate Cancer (free)
“Prebiopsy magnetic resonance imaging combined with targeted biopsy is associated with improved detection of clinically significant prostate cancer and reduced numbers of biopsy cores per procedure, while potentially avoiding unnecessary biopsies.”
Simulation Study: Uniform CT Imaging for Patients with Hematuria May Result in Increased Costs and Harms of Secondary Cancers
30 Jul, 2019 | 01:37h | UTCComparison of the Harms, Advantages, and Costs Associated With Alternative Guidelines for the Evaluation of Hematuria – JAMA Internal Medicine (free for a limited period)
Commentaries: Hematuria Practice Guidelines That Explicitly Consider Harms and Costs – JAMA Internal Medicine (free for a limited period) AND Evaluating Hematuria: Uniform Use of CT Seen as Risky and Expensive – NEJM Journal Watch (free)
Related Commentary on Twitter (Thread – Click for More)
Excited to have our work examining tradeoffs of alternative approaches to hematuria evaluation out in @JAMAInternalMed today. Sharing here origin story, highlights from the paper and related thoughts (THREAD)
1/nhttps://t.co/f47L2BZOW7— Matt Nielsen (@m_e_nielsen) July 29, 2019
Female Urethroplasty: A Practical Guide Emphasizing Diagnosis and Surgical Treatment of Female Urethral Stricture Disease
27 Jul, 2019 | 19:57h | UTC
Penile Lesions: Patient Presentation, Differential Diagnosis, and Management
27 Jul, 2019 | 15:19h | UTCRelated Reviews: Penile warts: an update on their evaluation and management – Drugs in Context (free) AND Noninfectious Penile Lesions – American Family Physician (free)
Study: Short MRI Protocols Have High Diagnostic Performance for Prostate Cancer Detection
23 Jul, 2019 | 01:18h | UTCCommentary: Fast MRI Protocol Accurately Identifies Prostate Cancer at Lower Cost – Medscape/Reuters (free)
[Abstract Only] Review: The Global Prevalence of Erectile Dysfunction
23 Jul, 2019 | 01:16h | UTCThe global prevalence of erectile dysfunction: a review – BJU International (link to abstract – $ for full-text)
Commentaries: How common is erectile dysfunction? – Medical News Today (free) AND Erectile Dysfunction Presents Large Global Health Burden – Renal & Urology News (free)
[Abstract Only] Observational Study Points to Increased Cardiovascular and Cerebrovascular Risk with Testosterone Replacement Therapy (TRT) in Aging Men
19 Jul, 2019 | 09:37h | UTCCardiovascular and Cerebrovascular Safety of Testosterone Replacement Therapy Among Aging Men with Low Testosterone Levels: A Cohort Study – American Journal of Medicine (link to abstract – $ for full-text)
Commentary: Testosterone replacement therapy (TRT) can increase men’s risk of stroke and heart attack – Elsevier (free)
Interventions to Treat Erectile Dysfunction and Premature Ejaculation: An Overview of Systematic Reviews
12 Jul, 2019 | 07:54h | UTCRelated Guidelines: Erectile Dysfunction: AUA Guideline (free) AND An Update of the International Society of Sexual Medicine’s Guidelines for the Diagnosis and Treatment of Premature Ejaculation – Sexual Medicine (free)
Androgen Deprivation Therapy Linked to Increased Risk of Dementia in Men with Prostate Cancer
10 Jul, 2019 | 09:30h | UTCCommentaries: Hormone therapy for prostate cancer may raise risk of Alzheimer’s, Dementia – Penn Medicine (free) AND Prostate cancer treatment linked to heightened Alzheimer’s risk – UPI (free) AND Men’s dementia risk higher after androgen deprivation therapy – OnMedica (free) AND Risk of dementia rises with prostate cancer hormone-blocking therapy – Reuters (free)
[Abstract Only] Randomized Trial: First-Line Therapies for Metastatic Prostate Cancer Compared
30 Jun, 2019 | 17:16h | UTCEnzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: ENZAMET Trial Shows Enzalutamide Improves Overall Survival in Hormone-Sensitive Metastatic Prostate Cancer – The ASCO Post (free)
[Abstract Only] Randomized Trial: Ultra-hypofractionated vs. Conventionally Fractionated Radiotherapy for Prostate Cancer
30 Jun, 2019 | 17:18h | UTCUltra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Related Commentary on Twitter
NEW Research—Ultra-hypofractionated versus conventionally fractionated radiotherapy for #prostatecancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial https://t.co/7weB2Qz3wc pic.twitter.com/mSUvbQHMdw
— The Lancet (@TheLancet) June 20, 2019
[Abstract Only] Meta-Analysis: Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess
25 Jun, 2019 | 06:33h | UTCNatural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Incidentally discovered adrenal tumors rarely grow or affect hormonal function, review finds – ACP Internist (free) AND Healthcare guidelines should be updated for patients with certain adrenal tumors – University of Birmingham (free)
Related Guideline: Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors – European Journal of Endocrinology (free)
Study: Association of Coworker Reports About Unprofessional Behavior by Surgeons With Surgical Complications in Their Patients
21 Jun, 2019 | 08:50h | UTCAssociation of Coworker Reports About Unprofessional Behavior by Surgeons With Surgical Complications in Their Patients – JAMA Surgery (free for a limited period)
Commentaries: When Surgeons Are Abrasive To Co-Workers, Patients’ Health May Suffer – NPR (free) AND Unprofessional Behavior by Surgeons Linked to Surgical Complications in Their Patients – MedicalResearch.com (free) AND After surgery, how patients fare may depend on how their doctor behaves, study says – CNN (free)
Small Observational Study Suggests Active Surveillance is Feasible for Small Renal Masses
20 Jun, 2019 | 05:56h | UTCCommentary: Active Surveillance Safe for Small Renal Tumors – MedPage Today (free registration required)
The Diagnosis and Treatment of Enuresis and Functional Daytime Urinary Incontinence
9 Jun, 2019 | 12:49h | UTC
Meta-Analysis: Surgical Interventions for Women with Stress Urinary Incontinence
6 Jun, 2019 | 06:08h | UTCRelated Commentary on Twitter
#BMJInfographic #VisualAbstract summarises new research on the effectiveness and harms of surgical interventions for stress urinary incontinence https://t.co/PWeHfzYjgA pic.twitter.com/x60OnfB9XY
— The BMJ (@bmj_latest) June 5, 2019
[Abstract Only] Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer
3 Jun, 2019 | 07:31h | UTCApalutamide for Metastatic, Castration-Sensitive Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Adding Apalutamide to ADT Prolongs Survival in mCSPC – Renal & Urology News (free) AND TITAN: OS benefit seen with apalutamide in metastatic CSPC setting – Medicine Matters (free)
[Abstract Only] Large Observational Study Suggests Vasectomy May Increase the Risk of Prostate Cancer
3 Jun, 2019 | 07:19h | UTCVasectomy and prostate cancer risk: a 38-year nationwide cohort study – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentary: Vasectomy Increases Prostate Cancer Risk Over Time – Medscape (free registration required)
[Abstract Only] Randomized Trial: Gentamicin vs. Ceftriaxone for the Treatment of Gonorrhea
28 May, 2019 | 00:51h | UTCGentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Clinical trial finds gentamicin inferior to ceftriaxone for gonorrhea – CIDRAP (free) AND Drug combination could be effective for treatment resistant gonorrhea – NIHR (free) AND New drug combination could be effective for treatment-resistant gonorrhea – OnMedica (free) AND Quick Take: Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG) – 2 Minute Medicine (free)
Recent Advances in the Management of Penile Cancer
26 May, 2019 | 12:32h | UTCRecent advances in the management of penile cancer – F1000Research (free)
Canadian Recommendations for the Management of the Incidental Renal Mass in Adults
24 May, 2019 | 05:07h | UTCRecommendations for the Management of the Incidental Renal Mass in Adults: Endorsement and Adaptation of the 2017 ACR Incidental Findings Committee White Paper by the Canadian Association of Radiologists Incidental Findings Working Group – Canadian Association of Radiologists Journal (free)
Final Overall Survival Analysis of the LATITUDE Trial in Newly Diagnosed, High-Risk, Metastatic, Castration-Sensitive Prostate Cancer
20 May, 2019 | 22:47h | UTCOriginal Article: Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial – The Lancet Oncology (link to abstract – 4 for full-text)
Current Status of MRI and PET in the NCCN Guidelines for Prostate Cancer
19 May, 2019 | 16:29h | UTC
NCCN Guideline: Prostate Cancer, Version 2.2019
19 May, 2019 | 16:23h | UTCRelated Guideline: NICE Guideline: Diagnosis and Management of Prostate Cancer (free)
Medical Management vs. Minimally Invasive Surgical Techniques for Lower Urinary Tract Symptoms due to BPH
16 May, 2019 | 05:43h | UTC