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Transplantation (all articles)

After a flurry of firsts, xenotransplantation is suddenly back in the spotlight.

25 Jan, 2022 | 09:09h | UTC

After a flurry of firsts, xenotransplantation is suddenly back in the spotlight – STAT

Related: In 1st, US surgeons transplant pig heart into human patient.

 

Consensus statement on hemostatic management, anticoagulation, and antiplatelet therapy in liver transplantation.

20 Jan, 2022 | 08:47h | UTC

Consensus Statement on Hemostatic Management, Anticoagulation, and Antiplatelet Therapy in Liver Transplantation – Transplantation

 

A single-arm study evaluated Naive T-Cell depleted peripheral blood stem-cell grafts for the prevention of chronic graft-versus-host disease.

19 Jan, 2022 | 08:22h | UTC

Naive T-Cell Depletion to Prevent Chronic Graft-Versus-Host Disease – Journal of Clinical Oncology

Commentary: New graft strategy may improve outcomes for blood stem cell recipients – University of Pittsburg

 

Clinical Guideline: Acute-on-chronic liver failure.

11 Jan, 2022 | 02:43h | UTC

Acute-on-Chronic Liver Failure Clinical Guidelines – American Journal of Gastroenterology

Related: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU

 

Commentary on Twitter

 

In 1st, US surgeons transplant pig heart into human patient.

11 Jan, 2022 | 02:34h | UTC

In 1st, US surgeons transplant pig heart into human patient – Associated Press

 

RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.

7 Dec, 2021 | 08:37h | UTC

Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results from a Phase 3 Randomized Clinical Trial – Clinical Infectious Diseases

 

CDC Guidance: Immunocompromised may need a fourth Covid-19 shot.

4 Nov, 2021 | 10:06h | UTC

Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States – Centers for Disease Control and Prevention

Commentaries:

Immunocompromised may need a fourth Covid-19 shot, CDC says – CNN

Some immunocompromised people can receive a 4th Covid shot, CDC says – NBC News

 

Review: Management of alcohol use disorder in patients with cirrhosis in the setting of liver transplantation.

3 Nov, 2021 | 09:45h | UTC

Management of alcohol use disorder in patients with cirrhosis in the setting of liver transplantation – Nature Reviews Gastroenterology & Hepatology

 

Commentary on Twitter

 

Recurrent Glomerular Disease after Kidney Transplantation: Diagnostic and Management Dilemmas.

28 Oct, 2021 | 09:43h | UTC

Recurrent Glomerular Disease after Kidney Transplantation: Diagnostic and Management Dilemmas – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

 

In a major scientific advance, a pig kidney is successfully transplanted into a human.

21 Oct, 2021 | 09:52h | UTC

In a major scientific advance, a pig kidney is successfully transplanted into a human – NPR

 

ASH 2021 guidelines for stem cell transplantation in patients with sickle cell disease.

14 Oct, 2021 | 09:53h | UTC

American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation – Blood

News release: ASH Releases New Clinical Practice Guidelines on Stem Cell Transplantation in Sickle Cell Disease

Commentary: ASH Issues Guideline on the Use of HSCT for Sickle Cell Disease – HealthDay

 

Bioethics | People who want organ transplants must get the COVID-19 vaccine, a hospital says.

8 Oct, 2021 | 10:21h | UTC

People who want organ transplants must get the COVID-19 vaccine, a hospital say – NPR

 

Long-Term Immunosuppression Management: Opportunities and Uncertainties.

7 Oct, 2021 | 10:15h | UTC

Long-Term Immunosuppression Management: Opportunities and Uncertainties – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

 

Consensus Guideline: Liver transplantation for non-resectable colorectal liver metastases.

16 Sep, 2021 | 09:50h | UTC

Liver transplantation for non-resectable colorectal liver metastases: the International Hepato-Pancreato-Biliary Association consensus guidelines – The Lancet Gastroenterology & Hepatology (free registration required)

 

Commentary on Twitter

 

How I Do It: Considering lung transplantation for patients with COVID-19.

24 Aug, 2021 | 09:55h | UTC

How I Do It: Considering lung transplantation for patients with COVID-19 – CHEST

 

Related:

Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries

Report: Lung transplantation for 3 patients with severe COVID-19

 

FDA authorizes additional Covid-19 vaccine dose for certain immunocompromised individuals – Other fully vaccinated individuals do not need an additional vaccine dose right now.

16 Aug, 2021 | 01:22h | UTC

Coronavirus (COVID-19) Update: FDA Authorizes Additional Vaccine Dose for Certain Immunocompromised Individuals – U.S. Food & Drug Administration

Commentaries:

Statement on FDA Authorization of Supplemental Vaccine Dose for Immunocompromised Patients – Infectious Diseases Society of America

CDC, FDA recommend COVID booster for immune-compromised – CIDRAP

FDA authorizes additional dose of Covid-19 vaccine for the immunocompromised – STAT

The fine print: Understanding the new policy authorizing extra Covid vaccine doses for the immunocompromised – STAT

Covid booster: US approves third jab for the immunocompromised – BBC

CDC Committee Approves Third Covid-19 Shot For Immunocompromised People—Here’s Who Should Get One – Forbes

CDC Panel Recommends 3rd Vaccine Dose For Immunocompromised People – NPR

6 Things To Know If You’re Immunocompromised And Considering A 3rd Shot – NPR

CDC recommends third Covid-19 vaccine dose for certain immunocompromised people – CNN

 

Commentary on Twitter

 

First World Consensus Conference on Pancreas Transplantation.

13 Aug, 2021 | 09:43h | UTC

Part I – methods and results of literature search – American Journal of Transplantation

Part II – recommendations – American Journal of Transplantation

 

RCT: third dose of Moderna mRNA vaccine increases immunity in transplant recipients.

12 Aug, 2021 | 09:56h | UTC

Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients – New England Journal of Medicine

Editorial: Third Time’s a Charm — Covid-19 Vaccine Hope for Solid-Organ Transplant Recipients

Related:

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

[Preprint] 3rd AstraZeneca shot gives strong immunity.

 

Commentaries on Twitter

https://twitter.com/hildabast/status/1425576801850433537

 

Review: Lung transplantation for interstitial lung disease.

5 Aug, 2021 | 08:32h | UTC

Lung transplantation for interstitial lung disease – European Respiratory Review

 

Donor drug use is not associated with worse recipient survival in heart transplantation – “Increasing use of such donors may help alleviate the chronic donor shortage.”

30 Jul, 2021 | 11:39h | UTC

Intoxicated Donors and Heart Transplant Outcomes: Long-Term Safety – Circulation: Heart Failure

Commentary: Donor Drug Use Not Tied to Survival for Heart Transplant Recipients – HealthDay

Related study: National Trends in Heart Donor Usage Rates: Are We Efficiently Transplanting More Hearts? – Circulation: Heart Failure

 

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

26 Jul, 2021 | 02:54h | UTC

Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses – JAMA

Commentary: Case Mounts for COVID Vaccine Boosters in Kidney Transplant Recipients – MedPage Today (free registration required)

Related:

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

[Preprint] 3rd AstraZeneca shot gives strong immunity.

 

Commentary on Twitter

 

RCT: Ruxolitinib for glucocorticoid-refractory chronic graft-versus-host disease.

16 Jul, 2021 | 10:37h | UTC

Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease – New England Journal of Medicine

 

Perspective | Should People With Immune Problems Get Third Vaccine Doses?

8 Jul, 2021 | 09:07h | UTC

Should People With Immune Problems Get Third Vaccine Doses? – The New York Times (a few articles per month are free)

Related: [Preprint] 3rd AstraZeneca shot gives strong immunity. AND Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

 

RCT: Similar outcomes with mycophenolate mofetil vs. azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression.

29 Jun, 2021 | 09:50h | UTC

Mycophenolate mofetil versus azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression (ATHENA): A pragmatic randomized trial – PLOS One

 

Three doses of an mRNA Covid-19 vaccine in solid-organ transplant recipients can improve the immunogenicity of the vaccine.

24 Jun, 2021 | 10:32h | UTC

Three Doses of an mRNA Covid-19 Vaccine in Solid-Organ Transplant Recipients – New England Journal of Medicine

 

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