TOP 10 Medical News Stories

Even slight changes within the normal Apgar score range (7-10) from five to 10 minutes have a major influence in the risks of cerebral palsy and epilepsy.

9 – Management of patients on antithrombotic agents undergoing emergency and elective endoscopy: joint Asian Pacific Association of Gastroenterology (APAGE) and Asian Pacific Society for Digestive Endoscopy (APSDE) practice guidelines – Gut (free)

10 – Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial – The Lancet child & Adolescent Health (link to abstract – $ for full-text)

Commentaries: Premature babies healthier when parents help with hospital care, study shows – The Guardian (free) AND Preemies Fared Better When Parents Helped with NICU Care – MedPage Today (free registration required) AND Parents’ care can help premature babies in hospital, says study – BBC News (free)

Thu, February 8 – 10 Stories of The Day!

8 Feb, 2018 | 00:15h | UTC

1 – Guideline: Pancreatic cancer in adults: diagnosis and management – National Institute for Health and Care Excellence (free)

News release: Pancreatic cancer patients should be offered early scans to avoid unnecessary surgery, says NICE (free)

2 – Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews – Cochrane Library (free)

Summary: Overview of Cochrane Reviews of interventions used during surgery for preventing surgical site infection (free)

3 – Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: For mortality prediction, qSOFA has poor sensitivity, moderate specificity, review finds – ACP Hospitalist (free) AND Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure assessment for predicting mortality in patients with suspected infection – 2 Minute Medicine (free)

4 – Opinion: This flu season, physicians need to scrap the ‘martyr culture’ of working while sick – STAT (free) (via @CMichaelGibson)

5 – New cellphone and health studies don’t eliminate uncertainty – Science (free)

Other commentaries: Largest Animal Study of Cell Phone Radiation and Cancer Risk – Medscape (free registration required) AND High doses of cellphone radiation linked to some cancers in rats – STAT (free) AND Cell phone radiation: Could high exposure cause tumors? – Medical News Today (free)

6 – Care-Centered Clinical Documentation in the Digital Environment: Solutions to Alleviate Burnout – National Academy of Medicine (free)

Related Infographic: Date Night with the EHR – NEJM Catalyst (free)

7 – ISPOR 2018 – Top 10 Health Economics and Outcomes Research Trends (free PDF)

Commentary: Top 10 Trends Driving Healthcare in 2018 – NewsWise (free)

8 – Report: Global Monitoring of Disease Outbreak Preparedness: Preventing the Next Pandemics – Harvard Global Health Institute (free PDF)

See also: News Release (free) AND Summary report (free PDF)

9 – Preoperative exercise halves the postoperative complication rate in patients with lung cancer: a systematic review of the effect of exercise on complications, length of stay and quality of life in patients with cancer – British Journal of Sports Medicine (link to abstract – $ for full-text)

Commentaries: Regular exercise halves complication rate after lung cancer surgery – eCancer News (free) AND Lung Cancer Postoperative Complications Reduced With Preoperative Exercise – Pulmonology Advisor (free)

10 – Association of Preoperatively Diagnosed Patent Foramen Ovale With Perioperative Ischemic Stroke – JAMA (free for a period)

Commentaries: PFO Diagnosis Linked With Increased Risk of Perioperative Ischemic Stroke After Noncardiac Surgery – TCTMD (free) AND Preoperatively Diagnosed PFO and Perioperative Stroke – American College of Cardiology, Latest in Cardiology (free)

Tue, February 6 – 10 Stories of The Day!

6 Feb, 2018 | 00:01h | UTC

2 – Viewpoint: Vitamin and Mineral Supplements: What Clinicians Need to Know – JAMA Internal Medicine (free for a period)

3 – Effect of Hot Tea Consumption and Its Interactions With Alcohol and Tobacco Use on the Risk for Esophageal Cancer: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Hot tea tied to higher cancer risk for smokers and drinkers – Reuters (free) AND Very hot tea can raise risk of oesophageal cancer, suggests study – The Guardian (free) AND Hot Tea and Increased Risk for Esophageal Cancer – Medscape (free registration required)

4 – Social exclusion heightens risk of death across many health conditions – NIHR Signal (free)

Original Article: Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis – The Lancet (free) AND Commentary: Inclusion health: addressing the causes of the causes (free) AND Review: What works in inclusion health: overview of effective interventions for marginalised and excluded populations (free registration required)

5 – Risk of pre-eclampsia in women taking metformin: a systematic review and meta-analysis – Diabetic Medicine (link to abstract – $ for full-text)

Source: ACP Journal Wise ($)

“Metformin was associated with lower gestational weight gain and a lower risk of pre-eclampsia compared with insulin”

6 – Heparin-Induced Thrombocytopenia in the Patient Who Is Critically Ill – Chest (free)

Source: Critical Care Reviews Newsletter

7 – Richard Smith: Doctors and patients heading in opposite directions – The BMJ Opinion (free)

“Patients increasingly have multiple conditions, while doctors continue remorseless specialisation and subspecialisation. What are the consequences of this divergence?” (via @bmj_latest see Tweet)

8 – Hydroxyethyl-starch solutions (HES) should no longer be used in patients with sepsis or burn injuries or in critically ill patients – European Medicines Agency (free)

Press release: Hydroxyethyl-starch solutions for infusion to be suspended (free)

Source: EMA calls for hydroxyethyl starch solutions to be taken off market – The BMJ News ($)

9 – 5 ways poorly thought out health IT can worsen patient safety – KevinMD.com (free)

10 – Use of social media is associated with short sleep duration in a dose–response manner in students aged 11 to 20 years – Acta Paediatrica (link to abstract – $ for full-text)

Commentary: Social media use linked to lack of sleep in students – Wiley, via EurekAlert (free)

See also a recent Pediatrics supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn (series of free articles) and related articles on Social Media and Mental Health

Wed, February 7 – 10 Stories of The Day!

7 Feb, 2018 | 00:01h | UTC

1 – Policy Statement: Recommended Childhood and Adolescent Immunization Schedules: United States, 2018 – American Academy of Pediatrics (free)

The Immunization Schedules for 2018 are available in the Red Book Online (free) and in the Centers for Disease Control and Prevention Website (free)

2 – Rapid Recommendations: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free text and infographics)

3 – Report: E-cigarettes and heated tobacco products: evidence review – Public Health England (free PDF)

News release: PHE publishes independent expert e-cigarettes evidence review (free)

Commentaries: UK experts urge smokers to switch to e-cigs for big health gains – Reuters (free) AND E-cigarettes ‘should be on prescription’ – BBC News (free) AND Doctors should encourage smokers to switch to vaping – OnMedica (free)

See related report recently released by the National Academies of Sciences, Engineering, and Medicine (free report and commentaries)

4 – Effect of an In-Hospital Multifaceted Clinical Pharmacist Intervention on the Risk of Readmission: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Clinical Pharmacist Intervention Can Reduce ED Visits and Hospital Readmissions – MedicalResearch.com (free) AND Pharmacist-led extended medication review and follow-up on discharge may decrease risk of readmission – 2 Minute Medicine (free)

5 – EAU Guidelines on Assessment and Nonsurgical Management of Urinary Incontinence – European Urology (free)

6 – AASLD guidelines for the treatment of hepatocellular carcinoma – Hepatology (free)

7 – Richard Lehman’s journal review, 5 February 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

8 – How Fake Surgery Exposes Useless Treatments – Scientific American (free)

9 – To eat or to breathe? The answer is both! Nutritional management during noninvasive ventilation – Critical Care (free)

10 – Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study – The Lancet Infectious Diseases (free)

Commentaries: Drug-resistant malaria spreading fast in Southeast Asia – CIDRAP (free) AND Drug-resistant malaria will spread without urgent action, experts warn – The Guardian (free) AND Multidrug resistant malaria spread under the radar for years in Cambodia – Wellcome Sanger Institute (free)

Mon, February 5 – 10 Stories of The Day!

5 Feb, 2018 | 00:01h | UTC

1 – World Cancer Day (4 February 2018) – World Health Organization (free)

New Document: Guide to cancer early diagnosis – World Health Organization (free)

News Release: Guide to Cancer Early Diagnosis (free)

See other key cancer documents by WHO

2 – Intrauterine Growth Restriction. Guideline of the German Society of Gynecology and Obstetrics – Geburtshilfe und Frauenheilkunde (free)

3 – BSH Guideline: management of thrombotic and haemostatic issues in paediatric malignancy – British Journal of Haematology (free)

4 – D-dimer Predicts Long-Term Cause-Specific Mortality, Cardiovascular Events and Cancer in Stable Coronary Heart Disease Patients: The LIPID Study – Circulation (link to abstract – $ for full-text)

Commentary: D-dimer Predicts Long-Term Mortality, Vascular Events, Cancer – American College of Cardiology, Latest in Cardiology (free) AND D-Dimer Predicts CV, Cancer Mortality Over 16 Years in Patients With Stable CHD – Medscape (free registration required)

5 – Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free)

6 – Pediatrics Supplement – Congenital Zika Syndrome (via @greg_folkers)

– Public Health Approach to Addressing the Needs of Children Affected by Congenital Zika Syndrome (free)

– Zika and Public Health: Understanding the Epidemiology and Information Environment (free)

– Development of Infants With Congenital Zika Syndrome: What Do We Know and What Can We Expect? (free)

– Ophthalmologic Manifestations Associated With Zika Virus Infection (free)

– Motor Abnormalities and Epilepsy in Infants and Children With Evidence of Congenital Zika Virus Infection (free)

– The Likely Impact of Congenital Zika Syndrome on Families: Considerations for Family Supports and Services (free)

7 – One Day Your Mind May Fade. At Least You’ll Have a Plan – The New York Times (10 articles per month are free)

Free download: Health Directive for Dementia (free PDF) from Advanced Directive for Dementia

Source: New document allows advance planning for dementia – Univadis (free registration required)

“A Simple Way to Document the Medical Care You Would Want If You Had Dementia”

8 – A revolution in health care is coming – The Economist (a few articles per month are free) (via @equitylist)

“Welcome to Doctor You”

9 – A Multicomponent, Preschool to Third Grade Preventive Intervention and Educational Attainment at 35 Years of Age – JAMA Pediatrics (free)

Commentaries: Longer Early Childhood Intervention Linked To Greater Post-Secondary Attainment – MedicalResearch.com (free) AND Does Preschool Make a Long-Term Difference? – MedPage Today (free) AND Graduates of early childhood program show greater educational gains as adults – EurekAlert (free)

10 – Prevalence of Pulmonary Embolism in Patients With Syncope – JAMA Internal Medicine (free for a period)

Author Interview: Prevalence of Pulmonary Embolism in Patients With Syncope (free)

Commentaries: Prevalence of PE Low for Patients Presenting to ER With Syncope – Physician’s Weekly (free) AND Study Finds Pulmonary Embolus Rarely the Cause of Syncope – MedicalResearch.com (free)

Fri, February 2 – 10 Stories of The Day!

2 Feb, 2018 | 00:01h | UTC

1 – Migraine and risk of cardiovascular diseases: Danish population based matched cohort study – The BMJ (free)

Editorial: Migraine and risk of cardiovascular disease (free)

Commentaries: Migraine Associated With Broad Range of CVD Diagnoses in Nationwide Study – TCTMD (free) AND Migraine Linked To Increased Risk of Stroke, AFib, PE and Cardiovascular Disease – MedicalResearch.com (free)

2 – High performance plasma amyloid-β biomarkers for Alzheimer’s disease – Nature (link to abstract – $ for full-text)

Commentaries: Expert reaction to biomarkers for amyloid-beta in Alzheimer’s disease – Science Media Centre (free) AND A Big Step toward a Blood Test for Alzheimer’s – Scientific American (free) AND Simple blood test spots dementia protein – Nature News (free) AND Alzheimer’s hope as scientists unveil blood test for early signs – The Guardian (free)

3 – Cardiovascular Disease and Breast Cancer: Where These Entities Intersect: A Scientific Statement From the American Heart Association – Circulation (free PDF)

Commentaries: Breast cancer treatments may increase the risk of heart disease – AHA / ASA Newsroom (free) AND Heart group warns of cardiovascular risks after treatment for breast cancer – STAT (free)

4 – Intravenous antibiotics, administered over 3 hours, are linked to lower death rates in sepsis – NIHR Signal (free)

Original article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)

5 – Early use of tranexamic acid reduces bleeding more effectively – NIHR Signal (free)

Original article: Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free) AND Invited Commentary: Tranexamic acid: is it about time? (free)

“It is now clearer that every 15-minute delay after the first hour can reduce survival by about 10%”.

6 – Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or 4 – Diabetes Care (link to abstract – $ for full-text)

Commentaries: How I learned to stop worrying and love metformin – NephJC (free) AND Adjusted-Dose Metformin Appears Safe in Patients With Type 2 Diabetes and Chronic Kidney Disease Stage 3 or 4 – PracticeUpdate (free registration required)

7 – Unnecessary Medical Care: More Common Than You Might Imagine – NPR Shots (free)

Original report: First, Do No Harm Calculating Health Care Waste in Washington State (free PDF)

Related commentary: When Evidence Says No, but Doctors Say Yes – The Atlantic (free)

8 – Technology: Amazon Wants to Disrupt Health Care in America. In China, Tech Giants Already Have – The New York Times (10 articles per month are free)

9 – Medical Education: Bringing medicine back to the bedside – ACP Internist (free)

10 – History of Childhood Kidney Disease and Risk of Adult End-Stage Renal Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Childhood Kidney Disease and Adult ESRD (free)

Commentaries: History of Childhood Kidney Disease Linked to Risk of ESRD – Physician’s Weekly (free) AND Childhood Kidney Disease Predicts Adult ESRD – MedPage Today (free registration required)

Thu, February 1 – 10 Stories of The Day!

1 Feb, 2018 | 00:01h | UTC

1 – Catheter Ablation for Atrial Fibrillation with Heart Failure – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Catheter ablation better than pharmacological atrial fibrillation therapies – University of Utah Health, via EurekAlert (free)

“In patients w/heart failure & atrial fibrillation, catheter ablation lowers rate of death and hospitalization for worsening HF vs. medical therapy”. (via @NEJM see Tweet)

2 – Guideline: Diagnosis and management of gastrointestinal complications in adult cancer patients – German Society of Hematology and Medical Oncology (free)

3 – Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks: Meta-analysis of 10 Trials Involving 77 917 Individuals – JAMA Cardiology (free)

Commentary: Omega-3 Supplements Don’t Protect Against Heart Disease – The New York Times (10 articles per month are free)

Omega-3 fatty acids did not prevent fatal or nonfatal coronary heart disease or any major vascular events.

4 – New Series on malaria in pregnancy – The Lancet Infectious Diseases (via @Onisillos)

Homepage

Comment: Putting malaria in pregnancy back in the spotlight (free registration required)

Article 1: Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem (free registration required)

Article 2: Prevention of malaria in pregnancy (free registration required)

Article 3: Treatment of uncomplicated and severe malaria during pregnancy (free registration required)

5 – Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study – PLOS One (free)

Commentaries: TBI is associated with increased dementia risk for decades after injury – PLOS, via ScienceDaily (free) AND More evidence traumatic brain injuries raise later dementia risk – Reuters (free)

“Using longitudinal, case-control, and sibling-matched analyses of nationwide data from Sweden, Peter Nordström & Anna Nordström describe the association between TBI and dementia, its time course, and the influence of familial factors”. (via @PLOSMedicine see Tweet)

6 – Pro/Con Debate – two doctors with opposite views on physician-assisted death:

Pro: I’m a doctor with end-stage cancer. I support medical aid in dying – STAT (free)

Con: Physician-assisted suicide won’t atone for medicine’s ‘original sin’ – STAT (free)

7 – Clinical Cancer Advances 2018: Annual Report on Progress Against Cancer from the American Society of Clinical Oncology (free)

Commentary: CAR T-Cell Immunotherapy Named Advance of the Year in ASCO’s Clinical Cancer Advances 2018 – The ASCO Post (free)

8 – CAR T-Cell Therapy – What do you need to know for the ED? – emDocs (free)

9 – Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline – Journal of Clinical Oncology (free)

Commentaries: ASCO Guideline Offers Recommendations for Management of Mesothelioma – Cancer Network (free) AND ASCO Releases First Mesothelioma Guideline – MedPage Today (free registration required)

10 – CDC Offers Refresher on Safe-sleep Practices for Infants – American Academy of Family Physicians (free)

Report: Vital Signs: Trends and Disparities in Infant Safe Sleep Practices, United States, 2009–2015 – Morbidity and Mortality Weekly Report (MMWR), CDC (free)

Wed, January 31 – 10 Stories of The Day!

31 Jan, 2018 | 00:33h | UTC

1 – Screening for Lung Cancer: CHEST Guideline and Expert Panel Report (free PDF)

Summary and commentary: New guideline released on lung cancer screening – ACP Internist (free)

2 – HbA_1c, diabetes and cognitive decline: the English Longitudinal Study of Ageing – Diabetologia (free)

Commentaries: The Startling Link Between Sugar and Alzheimer’s – The Atlantic (free) And Study Shows Long-Term Effects Of Diabetes And Prediabetes On The Brain – Forbes (free) AND New research shows diabetes and worse blood sugar control are associated with long-term cognitive decline – MedicalXpress (free) AND HbA_1c Levels in Diabetes Linked to Cognitive Decline – Medscape (free registration required)

3 – Viewpoint: Does Medicine Overemphasize IQ? – JAMA (free)

4 – Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries – The Lancet (link to abstract – $ for full-text)

Commentaries: What’s the 5-Year-Survival Rate For Cancer Patients Around The World? – NPR (free) AND Global improvement in cancer survival but international differences are still very wide – eCancer News (free)

5 – Periodontal Disease Assessed Using Clinical Dental Measurements and Cancer Risk in the ARIC Study – JNCI: Journal of the National Cancer Institute (free)

Commentaries: More evidence of link between severe gum disease and cancer risk – eCancer News (free) AND Evidence mounts of link between severe gum disease and various cancers – eCancer News (free) AND Severe Gum Disease Increases Both Cancer Risk and Mortality – Medscape (free registration required)

6 – Mid- and Long-Term Health Risks in Living Kidney Donors: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Analysis looks at long-term risks of living kidney donation – American College of Physicians, via EurekAlert (free) AND What Are The Health Risks To Living Kidney Donors? – MedicalResearch.com (free) AND Living kidney donors have low but elevated risk of renal failure – Reuters (free)

7 – Opinion: Pay for performance: a dangerous health policy fad that won’t die – STAT (free)

See related articles and commentaries on recent studies with disappointing results of P4P Programs

8 – Ministry of Health Clinical Practice Guidelines: Hypertension – Singapore Medical Journal (free PDF)

9 – Recommendations on the Use of Ultrasound Guidance for Adult Thoracentesis: A Position Statement of the Society of Hospital Medicine – Journal of Hospital Medicine (free)

10 – Safety of hydroxyanthracene derivatives for use in food – EFSA Journal (free)

Press release: EFSA confirms health concerns for hydroxyanthracene derivatives in food – European Food Safety Agency (free)

Commentary: Europe’s safety watchdog says laxatives may increase cancer risk – Reuters (free)

“This group of substances naturally occurs in plants such as aloe or senna species. Extracts containing them are used in food supplements for their laxative effect”. (from Press Release)

Mon, January 29 – 10 Stories of The Day!

29 Jan, 2018 | 01:14h | UTC

1 – Guideline: Sore throat (acute): antimicrobial prescribing – National Institute for Health and Care Excellence (NICE) (free)

News release: Use paracetamol to relieve a sore throat rather than antibiotics (free)

Commentaries: GPs should cut back on antibiotic prescriptions for sore throats, NICE says – GP (free) AND ‘Painkillers best option for sore throats’ say new NHS guidelines – NHS Choices (free)

Related guideline: Corticosteroids for sore throat – The BMJ (free)

2 – British Association of Dermatologists’ guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018 – British Journal of Dermatology (free)

3 – Association of parental supply of alcohol with adolescent drinking, alcohol-related harms, and alcohol use disorder symptoms: a prospective cohort study – The Lancet Public Health (free)

Commentaries: Parental supply and alcohol-related harm in adolescence: emerging but incomplete evidence – The Lancet Public Health (free) AND Expert reaction to study looking at parents giving alcohol to their teenage children, and alcohol-related risks – Science Media Centre (free) AND Parental provision of alcohol to teenagers does not reduce risks, compared to no supply, Australian study finds – ScienceDaily (free)

4 – Association Between Fluid Balance and Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a period)

Commentaries: Fluid Overload Boosts Mortality in Critically Ill Children – Medscape (free registration required)

5 – New series published to support the use of qualitative research in decision-making – World Health Organization (free) (via @olibiermann and @trishgreenhalgh)

The Series: Applying GRADE-CERQual to Qualitative Evidence Synthesis Findings – Implementation Science (free)

WHO Media Centre: Why is this new qualitative research tool (GRADE-CERQual) important? (free)

6 – Key Concepts for Informed Health Choices: a framework for helping people learn how to assess treatment claims and make informed choices – BMJ Evidence-Based Medicine (free) (via @Students4BE)

Related free resources: Testing Treatments Interactive AND Students 4 Best Evidence – Key Concepts

7 – Review: The incidental thyroid nodule – CA: A Cancer Journal for Clinicians (free)

8 – Current Approaches to Epistaxis Treatment in Primary and Secondary Care – Deutsches Ärzteblatt international (free)

9 – In the Land of the Skinny, People are Getting Fat – The New York Times (10 articles per month are free)

10 – A surgical procedure for shoulder pain is less effective than previously thought – NIHR Signal (free)

Original article: Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial – The Lancet (free) AND Editorial: No benefit of arthroscopy in subacromial shoulder pain (free)

Tue, January 30 – 10 Stories of The Day!

30 Jan, 2018 | 00:23h | UTC

1 – Report: Global Antimicrobial Resistance Surveillance System (GLASS) – World Health Organization (free PDF)

News Release: High levels of antibiotic resistance found worldwide, new data shows (free)

Commentaries: WHO releases its first report on global antibiotic resistance – CIDRAP (free) AND UN health agency finds high levels of antibiotic resistance to world’s most common infections – UN News Centre (free)

2 – Editorial: Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) (via @MaryDixonWoods)

“Broadly, overdiagnosis means making people patients unnecessarily, by identifying problems that were never going to cause harm or by medicalising ordinary life experiences through expanded definitions of diseases”.

3 – Diagnosis and management of congenital diaphragmatic hernia: a clinical practice guideline – Canadian Medical Association Journal (free)

4 – Shorter Versus Longer Courses of Antibiotics for Infection in Hospitalized Patients: A Systematic Review and Meta-Analysis – Journal of Hospital Medicine (free PDF)

Source: Hospital Medicine Virtual Journal Club

5 – Birth Defects Potentially Related to Zika Virus Infection During Pregnancy in the United States – JAMA (free for a period)

Commentaries: Birth defects climb in US areas with local Zika – CIDRAP (free) AND More birth defects in U.S. areas with Zika: U.S. health officials – Reuters (free)

6 – Increased risk of ischemic heart disease, hypertension, and type 2 diabetes in women with previous gestational diabetes mellitus, a target group in general practice for preventive interventions: A population-based cohort study – PLOS One (free)

Commentaries: Women who have gestational diabetes in pregnancy are at higher risk of future health issues – University of Birmingham, via ScienceDaily (free) AND Target Patients With Gestational Diabetes After Birth to Reduce Risks – Medscape (free registration required)

7 – Association of Exposure to Communities With Higher Ratios of Obesity with Increased Body Mass Index and Risk of Overweight and Obesity Among Parents and Children – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: Your Neighbors, Your Waistline – New York Times (10 articles per month are free) AND Is ‘Social Contagion’ at Play When It Comes to Obesity Risk? – MedPage Today (free registration required) AND Location of military assignment tied to obesity risk for families – Cardiovascular Business (free)

8 – Richard Lehman’s journal review, 29 January 2018 – The BMJ Opinion (free)

9 – WSES guidelines for the management of iatrogenic colonoscopy perforation – World Journal of Emergency Surgery (free)

10 – EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice – Annals of Rheumatic Diseases (free)

Fri, January 26 – 10 Stories of The Day!

26 Jan, 2018 | 00:45h | UTC

1 – Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Myocardial Infarction after Influenza Infection (free)

Commentaries: Flu infection raises risk of heart attack in week after diagnosis – STAT (free) AND Flu Virus Can Trigger A Heart Attack – NPR (free) AND Flu increases the risk of heart attack – Reuters (free)

The researchers identified a six-fold increased risk of heart attack in the 7 days after a flu diagnosis.

2 – Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports – The BMJ (free)

Editorial: Just one cigarette a day seriously elevates cardiovascular risk (free)

Commentaries: CHD and stroke risk seriously elevated with just one daily cigarette – OnMedica (free) AND Smoking Even One Cigarette a Day Raises Cardiovascular Risk – Medscape (free registration required) AND Smoking Just One Cigarette a Day Carries Substantial Risks – Physician’s First Watch (free)

3 – Guideline: Duration of Contact Precautions for Acute-Care Settings – Society for Healthcare Epidemiology of America (SHEA) (free)

Summary and commentary: New guidelines issued on contact precautions for C. diff, resistant infections – ACP Hospitalist (free)

4 – Guideline: International technical guidance on sexuality education: An evidence-informed approach – UNESCO (free PDF)

News release: UN urges Comprehensive Approach to Sexuality Education – UNESCO (free)

Commentary: UN issues more progressive guidelines on sex education – Devex (free)

5 – Association of Resting Heart Rate and Temporal Changes in Heart Rate With Outcomes in Participants of the Atherosclerosis Risk in Communities Study – JAMA Cardiology (free)

Commentaries: Heart Rate Changes Over Time Hint at Higher Cardiovascular Risk – TCTMD (free) AND Increasing Heart Rate Over Time May Predict CV Events – MedPage Today (free registration required)

6 – Existing and potential infection risk zones of yellow fever worldwide: a modelling analysis – The Lancet Global Health (free)

7 – Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis – PLOS Medicine (free)

Commentaries: Caesarean section versus natural birth – an obstetrician examines a new review – The Conversation (free) AND Expert reaction to review paper looking at long-term risks and benefits of caesarean sections – Science Media Centre (free) AND C-sections linked to long-term risks and benefits – PLOS, via EurekAlert (free) AND Long-term risks and benefits of C-section revealed – Medical News Today (free)

“As a scientist, I can appreciate the effort made in conducting a systematic review on the topic, but as an obstetrician I worry that the results can be over-interpreted by patients – not to mention obstetricians and midwives – and caesarean section “marketed” as a safe way to avoid pelvic floor problems”. (from The Conversation)

8 – Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised controlled trial – The BMJ (free)

Commentaries: Pre-surgery breathing physio halves risk of complications – OnMedica (free) AND Respiratory Training Before Surgery Significantly Reduces Risk of Postoperative Lung Complications – Medindia (free) AND Breath Training Before Surgery Halves Postoperative Pneumonia Risk – Medscape (free registration required)

9 – Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer – Cell (free)

Commentaries: These monkey twins are the first primate clones made by the method that developed Dolly – Science (free) AND First monkeys cloned with technique that made Dolly the sheep – Nature (free) AND How afraid of human cloning should we be? – The Guardian (free)

10 – Projections of multi-morbidity in the older population in England to 2035: estimates from the Population Ageing and Care Simulation (PACSim) model – Age and Ageing (free)

Commentaries: Number of older people with four or more diseases will double by 2035 – OnMedica (free) AND Number of older people with four or more diseases will double by 2035 – Newcastle University (free) AND We’ll live longer but suffer more ill-health by 2035, says study – The Guardian (free)

See related articles and commentaries on Designing Health Care Systems for Patients with Complex Needs (free)

Wed, January 24 – 10 Stories of The Day!

24 Jan, 2018 | 01:18h | UTC

1 – Report: Public Health Consequences of E-Cigarettes – National Academies of Sciences, Engineering, and Medicine (free PDF)

Press release: New Report One of the Most Comprehensive Studies on Health Effects of E-Cigarettes; Finds That Using E-Cigarettes May Lead Youth to Start Smoking, Adults to Stop Smoking (free)

Commentaries: E-Cigarettes Likely Encourage Kids To Try Tobacco But May Help Adults Quit – NPR (free) AND 4 big takeaways from the most comprehensive report on e-cigarettes yet – VOX (free) AND Vaping Can Be Addictive and May Lure Teenagers to Smoking, Science Panel Concludes – The New York Times (10 articles per month are free)

2 – Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study – The BMJ (free)

See prognostic calculator: Prediction models for 3 month outcome after aSAH

3 – Antithyroid Drugs and Congenital Malformations: A Nationwide Korean Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: First trimester exposure to antithyroid drugs associated with increased risk of birth defects – 2 Minute Medicine (free) AND Use of Antithyroid Drugs Early in Pregnancy Tied to Birth Defect Risk – Physician’s First Watch (free) AND First trimester exposure to antithyroid drugs linked with birth defects – OnMedica (free)

4 – Advocacy for Improving Nutrition in the First 1000 Days To Support Childhood Development and Adult Health – Pediatrics (free)

Commentary: AAP Issues Recommendations for Improving Early-Childhood Nutrition – Physician’s First Watch (free) AND These Are the Best Foods for a Baby’s Brain – TIME (free)

5 – Robust research needs many lines of evidence – Nature (free)

6 – Parkinson’s disease in the ED: a potpourri of hyperpyrexia, dyskinesias, psychosis, and autonomic dysfunction – emDocs (free)

7 – Management of severe community acquired pneumonia in the emergency department – Journal of Emergency Medicine and Critical Care (free)

Source: Critical Care Reviews Newsletter

8 – Choosing Wisely Campaign: American Society of Breast Surgeons – Benign Breast Disease: Five Things Physicians and Patients Should Question (free)

Commentary: Choosing Wisely: 5 Procedures to Avoid in Benign Breast Disease – Physician’s First Watch (free)

See more on the Choosing Wisely initiative in our April 5 issue (see #6)

9 – Reduction of PTSD Symptoms With Pre-Reactivation Propranolol Therapy: A Randomized Controlled Trial – American Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Propranolol May Help Patients With PTSD – Psychiatric News Alert (free) AND Propranolol May Fill ‘Dire’ Treatment Need for PTSD – Medscape (free registration required)

10 – Starting antiretroviral therapy immediately after HIV diagnosis reduces transmission of the virus – NIHR Signal (free)

Original article: Implications for a policy of initiating antiretroviral therapy in people diagnosed with human immunodeficiency virus: the CAPRA research programme – Programme Grants for Applied Research (free)

Thu, January 25 – 10 Stories of The Day!

25 Jan, 2018 | 00:56h | UTC

1 – 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)

Commentaries: More stroke patients eligible for crucial treatments under new guidelines – American Heart Association News (free) AND More stroke patients may receive crucial treatments under new guideline – AHA/ASA Newsroom (free)

“A new guideline for treating acute ischemic stroke recommends an increased treatment window for mechanical clot removal from six hours to up to 24 hours in certain patients with clots in large vessels”. (from AHA/ASA Newsroom)

2 – Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging – New England Journal of Medicine (free)

Commentaries: Brain-scan guided emergency stroke treatment can save more lives – NIH News Releases (free) AND Study confirms late clot extraction can save brain cells of stroke victims – Reuters (free) AND New Findings Could Save Lives of More Stroke Patients – The New York Times (10 articles per month are free)

Related article: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct – New England Journal of Medicine (link to abstract – $ for full-text)

3 – Perspectives: To Care Is Human — Collectively Confronting the Clinician-Burnout Crisis – New England Journal of Medicine (free) AND Beyond Burnout — Redesigning Care to Restore Meaning and Sanity for Physicians (free)

4 – Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus – JAMA Neurology (free for a period)

Editorial: Time May Be of the Essence in the Treatment of Pediatric Patients With Refractory Convulsive Status Epilepticus (free)

Commentary: Delays Raise Death Risk in Kids with Status Epilepticus – MedPage Today (free registration required)

“These findings may change the perception of acute seizure and status epilepticus treatment, tentatively converting it into an extremely time-sensitive emergency that is similar to stroke or other cardiovascular events”.

5 – Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia: Evidence-based clinical practice guideline – Canadian Family Physician (free)

6 – ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis – European Journal of Neurology (free)

7 – Guideline: Oesophago-gastric cancer: assessment and management in adults – National Institute for Health and Care Excellence (NICE) (free)

8 – Guideline: Age-related macular degeneration – National Institute for Health and Care Excellence (NICE) (free)

9 – Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery – JAMA (free)

Commentaries: Largest Study to Date Supports Surgical LAA Closure in A-fib Patients – TCTMD (free) AND Thromboembolism Less Likely With LAA Closure Added to Cardiac Surgery – MedPage Today (free registration required)

Randomized trials are needed to confirm these interesting findings.

10 – Trends in Survival After In-Hospital Cardiac Arrest During Nights and Weekends – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Survival From In-Hospital Cardiac Arrest Improves But Still Worse on Nights and Weekends – MedicalResearch.com (free)

AND Hospital patients less likely to survive ‘off-hours’ cardiac arrest – Reuters (free) AND You are still more likely to die in a hospital on the weekend – CNN (free)

Mon, January 22 – 10 Stories of The Day!

22 Jan, 2018 | 00:11h | UTC

1 – Adjunctive Glucocorticoid Therapy in Patients with Septic Shock – New England Journal of Medicine (free)

Commentaries: The Definitive Word on Steroids in Septic Shock – Emergency Medicine Literature of Note (free) AND Adrenal – The Bottom Line (free)

“For the primary outcome, there was no statistically significance difference in mortality at 90 days – 27.9% in the hydrocortisone cohort, and 28.8% with placebo. Looking at secondary outcomes, the results here tended to favor hydrocortisone – a slightly faster resolution of shock, shorter ICU stays, and, oddly, decreased transfusion requirements”. (from Emergency Medicine Literature of Note Blog)

2 – Critical Care Reviews Book 2018 (free PDF)

“The Critical Care Reviews Book summarizes, critiques and puts in context the biggest trials of the year”.

3 – Weekend Surgical Care and Postoperative Mortality: A Systematic Review and Meta-Analysis of Cohort Studies (free)

Commentary: Evidence Supports ‘Weekend Effect’ for Mortality after Surgery – Wolters Kluwer, via NewsWise (free)

“The odds of postoperative mortality were 27 percent higher for patients admitted to the hospital on Saturday or Sunday, compared to those hospitalized on a weekday” (from NewsWise).

4 – Women’s reproductive factors and incident cardiovascular disease in the UK Biobank – Heart (link to abstract – $ for full-text)

Commentaries: Starting periods before age of 12 linked to heightened risk of heart disease and stroke – The BMJ, via EurekAlert (free) AND Early periods linked to heightened cardiovascular risk – OnMedica (free) AND Starting periods early linked to health risks later in life – Medical News Today (free) AND Early menarche and menopause linked to cardiovascular disease risk – The Guardian (free)

5 – To improve global health, tax the things that are killing us – Financial Times (free)

6 – Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference – EP Europace (free)

7 – Italian guidelines on the assessment and management of pediatric head injury in the emergency department – Italian Journal of Pediatrics (free)

8 – Postsurgical prescriptions for opioid naive patients and association with overdose and misuse: retrospective cohort study – The BMJ (free)

“The duration of treatment rather than dose is more strongly associated with opioid misuse after surgery, concludes this study” (via @bmj_latest see Tweet)

9 – Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community – Proceedings of the National Academy of Sciences (free)

Commentaries: Study confirms flu spreads by aerosols, not just coughs, sneezes – CIDRAP (free) AND Flu may be spread just by breathing, new UMD-led study shows – University of Maryland, via EurekAlert (free)

10 – Staying on antidepressants may prevent a relapse of anxiety – NIHR Signals (free)

Original article: Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials – The BMJ (free)

Tue, January 23 – 10 Stories of The Day!

23 Jan, 2018 | 01:20h | UTC

1 – Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Hyperthermic intraperitoneal chemotherapy with surgery increases survival for epithelial ovarian cancer patients – 2 Minute Medicine (free) AND Add-On Hyperthermic Intraperitoneal Chemotherapy Assessed in Ovarian CA – MPR (free)

Patients treated with hyperthermic intraperitoneal chemotherapy associated with surgery had increased median overall survival compared to patients treated with surgery alone (45,7 months vs 33,9 months).

2 – Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Synopsis of the 2017 American College of Cardiology/American Heart Association Hypertension Guideline – Annals of Internal Medicine (free)

3 – Clinical guideline and recommendations on pre-operative exercise training in patients awaiting major non-cardiac surgery – Anaesthesia (free)

4 – Review: Treatment of anxiety disorders – Dialogues in Clinical Neuroscience (free)

5 – Review: Update on the management of venous thromboembolism – Cleveland Clinic Journal of Medicine (free)

6 – Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials – Critical Care (free) (via @fpereirapa)

7 – Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? – Journal of General Internal Medicine (free for a period)

8 – Richard Lehman’s journal review, 22 January 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

9 – The Right Place at the Right Time: Medical Oncology Outpatients’ Perceptions of Location of End-of-Life Care – JNCCN (free)

Commentary: Let’s Talk About End-of-Life Care – National Comprehensive Cancer Network, via NewsWise (free)

“…majority of people with cancer would like their physicians to ask them where they would prefer to receive end-of-life care” (from NewsWise).

10 – Evidence-Based Guidelines for Fatigue Risk Management in Emergency Medical Services – Prehospital Emergency Care (free)

Commentaries in the same issue: Evidence-Based Guidelines for Fatigue Risk Management in Emergency Medical Services: A Significant Step Forward and a Model for Other High-Risk Industries (free) AND What an Evidence-based Guideline for Fatigue Risk Management Means for Us: Statements From Stakeholders (free) AND Proposed Performance Measures and Strategies for Implementation of the Fatigue Risk Management Guidelines for Emergency Medical Services (free) AND Evidence-Based Guidelines for Fatigue Risk Management in Emergency Medical Services: A Step in the Right Direction Toward Better Sleep Health (free)

Thu, January 18 – 10 Stories of The Day!

18 Jan, 2018 | 01:04h | UTC

1 – Household-Contact Investigation for Detection of Tuberculosis in Vietnam – The New England Journal of Medicine (free)

Quick Take Video Summary: Contact Investigation for Tuberculosis (free)

2 – Interventions to increase tuberculosis case detection at primary healthcare or community-level services – Cochrane Library (free)

Summary: Interventions to increase the number of tuberculosis cases being diagnosed – Evidently Cochrane (free)

Commentary: Cochrane review of effectiveness of strategies to improve access to treatment for TB – Liverpool School of Tropical Medicine, via EurekAlert (free)

3 – Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Monoclonal Gammopathy of Undetermined Significance: Risk for Progression to Cancer, Other Disorders Examined – Physician’s First Watch (free) AND Patients with blood cancer precursor at risk of developing cancer even after 30 years – Mayo Clinic, via EurekAlert (free)

4 – Catalogue of Bias – Centre for Evidence-Based Medicine, University of Oxford (free)

“25 biases affecting evidence on health kick off the new @CebmOxford Catalog of Bias” (via @hildabast see Tweet)

5 – Identifying older adults at risk of harm following elective surgery: a systematic review and meta-analysis – BMC Medicine (free)

Commentary: Age itself is not a risk factor for complications after surgery among older patients – OnMedica (free)

“Q: What predicts poor outcome after elective surgery in older people?

A: Frailty, cognitive impairment, depression, smoking but NOT age per se”. (via @trishgreenhalgh see Tweet)

6 – Richard Smith: The corruption of medical language – The BMJ Opinion (free)

“Too often, academic journals are filled with complex language and turgid prose, which is intended not to inform the reader but to ennoble the writer”. (via @bmj_latest see Tweet)

7 – Red and processed meat consumption and breast cancer: UK Biobank cohort study and meta-analysis – European Journal of Cancer (link to abstract – $ for full-text)

Commentaries: Processed meat ‘cancer risk’ in older women – OnMedica (free) AND Consumption of processed meat may increase the risk of breast cancer, according to a new study – MedicalXpress (free)

8 – Review: What works in inclusion health: overview of effective interventions for marginalised and excluded populations – The Lancet (free registration required)

9 – Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial – The Lancet (free)

Commentaries: Learning from TARDIS: time for more focused trials in stroke prevention – The Lancet (free) AND Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke – TARDIS – American College of Cardiology, Latest in Cardiology (free)

“Among patients with recent cerebral ischaemia, intensive antiplatelet therapy did not reduce the incidence and severity of recurrent stroke or TIA, but did significantly increase the risk of major bleeding. Triple antiplatelet therapy should not be used in routine clinical practice”.

10 – Early Recurrence and Major Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Treated With Non–Vitamin‐K Oral Anticoagulants (RAF‐NOACs) Study – Journal of the American Heart Association (free)

“Composite rates of recurrence and major bleeding were 12.4% in patients who initiated NOACs within 2 days after acute stroke, 2.1% in those who initiated NOACs between 3 and 14 days, and 9.1% in patients who initiated NOACs >14 days after acute stroke. Future randomized studies to assess timing of initiation and choice of agent in patients with acute stroke and AF are warranted”.

Fri, January 19 – 10 Stories of The Day!

19 Jan, 2018 | 01:42h | UTC

1 – The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients: Part 1 – Karger, Urologia Internationalis (free) (via @CIDRAP_ASP see Tweet)

2 – Detection and localization of surgically resectable cancers with a multi-analyte blood test – Science (link to abstract – $ for full-text)

Commentaries: Simple blood test detects eight different kinds of cancer – Nature News (free) A new blood test can detect eight different cancers in their early stages – The Conversation (free) AND CancerSEEK: Blood Test That Detects Eight Common Cancers – Medscape (free registration required) AND Scientists Edge Closer To A Blood Test To Detect Cancers – NPR (free) And Blood test could use DNA to spot early-stage cancers, study shows – The Guardian (free)

3 – Perspective: Redefining Hypertension: Assessing the New Blood-Pressure Guidelines – New England Journal of Medicine (free)

4 – Video: Pandemics – a worrying global public health threat (free) (via @RSTMH see Tweet)

5 – Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial – The Lancet (free)

Editorial: A new powerful drug to combat river blindness (free)

6 – Association of Dietary Inflammatory Potential With Colorectal Cancer Risk in Men and Women – JAMA Oncology (free)

Author interview: Dietary Inflammatory Potential and Risk of Colorectal Cancer in Men and Women (free)

Commentary: Why certain diets may increase your cancer risk – VOX (free)

7 – The Best Response to Medical Errors? Transparency – AAMC News (free)

8 – Patient reminder and recall interventions to improve immunization rates – Cochrane Library (link to abstract – $ for full-text)

Commentaries: Boosting vaccination rates with reminders: new Cochrane evidence – Evidently Cochrane (free) AND Sending out reminders/recalls can drive up immunisation rates – OnMedica (free) AND Patient Reminders Improve Vaccination Rates in Primary Care – Physician’s First Watch (free)

9 – Video: Early Palliative Care: a video for health and care professionals – University of Edinburgh (free) (via @OUPMedicine see Tweet)

10 – Prescribing Cascade in a Cardiology Practice – American College of Cardiology, Latest in Cardiology (free)

“Before starting a medication to treat a new medical condition, consider whether this condition could be a drug-related adverse event. Specifically, consider whether this could represent a prescribing cascade”.

Wed, January 17 – 10 Stories of The Day!

17 Jan, 2018 | 01:08h | UTC

1 – Association of Bariatric Surgery Using Laparoscopic Banding, Roux-en-Y Gastric Bypass, or Laparoscopic Sleeve Gastrectomy vs Usual Care Obesity Management With All-Cause Mortality – JAMA (link to abstract – $ for full-text)

Commentaries: Bariatric Surgery Prolongs Lifespan in Obese – Northwestern University, via NewsWise (free) AND Obesity surgery ‘halves risk of death’ compared with lifestyle changes – The Guardian (free) AND Bariatric Tx Bests Usual Care for Long-Term Health – MedPage Today (free registration required)

2 – Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Laparoscopic Gastric Sleeve Compared to Bypass Bariatric Surgery – RheumNow (free) AND No Clinical Significance in Weight Loss Among Sleeve Gastrectomy and Gastric Bypass Patients – AJMC (free) AND Weight-Loss Surgery Approaches Offer Similar Results – MedPage Today (free registration required) AND Rise of Sleeve Gastrectomy Is No Therapeutic Misadventure – Medscape (free registration required) AND Newer weight-reduction surgery effective, but may worsen acid reflux – Reuters (free)

3 – Association of Bariatric Surgery vs Medical Obesity Treatment With Long-term Medical Complications and Obesity-Related Comorbidities – JAMA (link to abstract – $ for full-text)

Commentaries: Bariatric Surgery for Obesity Reduces Some Risks, Raises Others – Medscape (free registration required)

4 – USPSTF Not Backing Ankle-Brachial Index, CRP, or Coronary Calcium – MedPage Today (free registration required) AND No Change in USPSTF’s Stance on Using Nontraditional Risk Factors to Assess CV Risk – Physician’s First Watch (free)

Draft Recommendation Statement 1: Cardiovascular Disease: Risk Assessment With Nontraditional Risk Factors – USPSTF (free)

Draft Recommendation Statement 2: Peripheral Artery Disease and Cardiovascular Disease: Screening and Risk Assessment With the Ankle-Brachial Index (free)

“The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of adding the ankle-brachial index (ABI), high-sensitivity C-reactive protein (hsCRP), or coronary artery calcification (CAC) score to traditional risk assessment for cardiovascular disease (CVD) in asymptomatic adults to prevent CVD events”.

5 – Adverse effects of caffeinated energy drinks among youth and young adults in Canada: a Web-based survey – CMAJ Open (free)

Commentaries: Over half of 12-24 year olds have side effects from energy drinks, survey reports – NHS Choices (free) AND Energy drinks can negatively impact health of youth – University of Waterloo, via ScienceDaily (free)

Related Position Statement: Energy and sports drinks in children and adolescents – Canadian Pediatric Society (free)

6 – Medical News & Perspectives: Interest in the Ketogenic Diet Grows for Weight Loss and Type 2 Diabetes – JAMA (free)

7 – Case Report: Snap, crackle and pop: when sneezing leads to crackling in the neck – BMJ Case Reports (free)

Commentaries: Man Ruptures His Throat By Stifling A Big Sneeze, Prompting Doctors’ Warning – NPR (free) AND Here Is What Can Happen If You Hold In A Sneeze – Forbes (free)

8 – Trial of Contralateral Seventh Cervical Nerve Transfer for Spastic Arm Paralysis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Swapping cervical nerves – Richard Lehman’s journal reviews (free) AND Nerve Transfer May Restore Function in Stroke Victims – MedPage Today (free registration required)

9 – FDA News Release: FDA acts to protect kids from serious risks of opioid ingredients contained in some prescription cough and cold products by revising labeling to limit pediatric use (free)

Commentaries: FDA strengthens warning on opioid cold medicine – CNN (free) AND FDA: Children should not take cough medicine with codeine – AAP News (free) AND FDA Updates Labeling for Opioid-Containing Medications to Limit Use in Children – Pharmacy Times (free) AND No Opioid Cough Meds in Children Under 18, FDA Says – Medscape (free registration required)

10 – Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices – Morbidity and Mortality Weekly Report (MMWR), CDC (free)

Commentary: ACIP: Updated Recommendations for Hepatitis B Virus Infection Prevention – MPR (free)

Tue, January 16 – 10 Stories of The Day!

16 Jan, 2018 | 00:17h | UTC

1 – European Resuscitation Council Guidelines for Resuscitation: 2017 update (free)

Source: Critical Care Reviews Newsletter

2 – Editorial: The natural environment and emergence of antibiotic resistance – The Lancet Planetary Health (free)

3 – Effect of Changing Work Stressors and Coping Resources on the Risk of Type 2 Diabetes: The OHSPIW Cohort Study – Diabetes Care (link to abstract – $ for full-text)

Commentary: Increased stress at work linked to higher risk of diabetes – Reuters (free)

4 – Transfer of Fresh versus Frozen Embryos in Ovulatory Women – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Frozen vs. fresh embryos for IVF? Study finds little impact on fertility – Yale News (free) AND Frozen just as good as fresh embryo when it comes to success in IVF, study shows – The Sydney Morning Herald (free) AND Live-birth rates similar among ovulating women undergoing fresh- or frozen-embryo transfer – 2 Minute Medicine (free) AND Fresh Embryos as Good as Frozen Ones for In Vitro Fertilization – The New York Times (10 articles per month are free)

5 – Childhood trajectories of peer victimization and prediction of mental health outcomes in midadolescence: a longitudinal population-based study – Canadian Medical Association Journal (free)

Commentary: Teens who were severely bullied as children at higher risk of suicidal thoughts, mental health issue – CMAJ, via EurekAlert (free)

6 – Effect of the School-Based Telemedicine Enhanced Asthma Management (SB-TEAM) Program on Asthma Morbidity: A Randomized Clinical Trial – JAMA Pediatrics (free)

Commentaries: School-based telemedicine enhances asthma management in children – 2 Minute Medicine (free) AND For City Kids with Asthma, Telemedicine and In-School Care Cut ER Visits in Half – University of Rochester (free)

7 – Can Your Hip Replacement Kill You? – The New York Times (10 articles per month are free)

“Lawsuits are pulling back the curtain on what some doctors call the Wild West of medicine: the untested and largely unregulated medical device industry” (via @NYTHealth see Tweet)

8 – Amyotrophic lateral sclerosis – Nature Reviews Disease Primers (free)

9 – Richard Lehman’s journal review, 15 January 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

10 – Primary prophylaxis of invasive fungal infections in patients with haematological malignancies: 2017 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO) (free)

Mon, January 15 – 10 Stories of The Day!

15 Jan, 2018 | 00:22h | UTC

1 – International guidelines for groin hernia management – HerniaSurge Group (free)

2 – Excerpt from the Canadian Ophthalmological Society evidence-based clinical practice guidelines for the management of diabetic retinopathy – Canadian Journal of Ophthalmology (free)

Commentary in: Clinical Practice Guidelines, December 2017 – Medscape (free registration required)

3 – Breast Implants and the Risk of Anaplastic Large-Cell Lymphoma in the Breast – JAMA Oncology (link to abstract – $ for full-text)

Commentaries: Breast Implants Associated With Increased Risk of Breast Anaplastic Large-cell Lymphoma – Oncology Nurse Advisor (free) AND Dutch Study Links Implants to Increased Breast-ALCL Risk – MedPage Today (free registration required)

4 – Editorial: Children and social media – The Lancet (free)

Original report: Life in ‘likes’ – Children’s Commissioner (free)

See also a recent Pediatrics supplement on Children, Adolescents and Screens (free articles) and other commentaries on Social Media and Mental Health (free articles)

5 – Reversing the Cardiac Effects of Sedentary Aging in Middle Age—A Randomized Controlled Trial: Implications For Heart Failure Prevention – Circulation (free PDF)

Commentaries: Exercise Study Hints at Volume, Intensity Levels Needed to Improve Cardiac Fitness in Middle Age – TCTMD (free) AND Exercise in middle age can reverse heart effects of sedentary lifestyle – Cardiovascular Business (free) AND Exercise May Reverse Negative Cardiac Effects of Sedentary Life – Medscape (free registration required) AND Exercise is good for you, but did this study actually show it can ‘reverse damage from heart aging’? – HealthNewsReview (free)

6 – How to Counter the Circus of Pseudoscience – The New York Times (10 articles per month are free)

7 – What I’ve learned from my tally of 757 doctor suicides – The Washington Post (free)

Related: Why are doctors killing themselves? – MJA InSight (free) AND Why are doctors plagued by depression and suicide? A crisis comes into focus – STAT (free) AND Protecting interns and other physicians from depression and suicide – STAT (free)

8 – Supporting Patients Through Serious Illness and the End of Life: Sutter Health’s AIM Model – The Commonwealth Fund (free)

“By proactively managing care for the terminally ill, the Advanced Illness Management program has produced savings of $8,000–$9,000 per patient” (via @commonwealthfnd see Tweet)

9 – Supported employment helps people with severe mental illness to obtain work – NIHR Signal (free)

Original article: Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta-analysis – Cochrane Library (link to abstract – $ for full-text)

10 – Antipsychotics and the Risk of Aspiration Pneumonia in Individuals Hospitalized for Nonpsychiatric Conditions – Journal of the American Geriatrics Society, via Medscape (free registration required)

Commentary: Antipsychotics May Increase Risk of Aspiration Pneumonia in Older Adults – Psychiatric News Alert (free)

Fri, January 12 – 10 Stories of The Day!

12 Jan, 2018 | 00:55h | UTC

1 – Bioethics: 200th anniversary of Mary Shelley’s Frankenstein (selected free texts)

‘Frankenstein’ Reflects The Hopes And Fears Of Every Scientific Era – The Atlantic (Free) AND The Horror Story That Haunts Science: Two Hundred Years Later, Frankenstein still Shocks And Inspires – Science (free) AND Infographic: Creating a modern monster – Science (free) AND Taming the Monsters of Tomorrow – Science (free) AND Dr Frankenstein’s Bioethical Experiment – The Lancet (Free Registration Required)

2 – Subclinical device-detected atrial fibrillation and stroke risk: a systematic review and meta-analysis – European Heart Journal (free)

See related opinion and commentaries in Get Ready For A Tsunami Of ECGs

3 – Which stent is best for heart attacks? – Evidently Cochrane (free)

Original article: Drug-eluting stents versus bare-metal stents for acute coronary syndrome – Cochrane Library (free)

“The current review suggests that using DES rather than BMS may reduce the need for future coronary procedures but there is no evidence that it saves lives or reduces major cardiovascular events”.

4 – Attention-Deficit/Hyperactivity Disorder and Very Preterm/Very Low Birth Weight: A Meta-analysis – Pediatrics (free)

Commentaries: Premature Infants Particularly Vulnerable to ADHD – Psychiatric Times (free) AND ADHD and Early Experience: Revisiting the Case of Low Birth Weight – Pediatrics (free)

5 – Acid-Suppressive Drug Use During Pregnancy and the Risk of Childhood Asthma: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)

Commentaries: Antacids During Pregnancy Tied to Asthma in Children – The New York Times (10 articles per month are free) AND Is antacid use during pregnancy tied to childhood asthma? – Reuters (free)

6 – Prenatal exposure to acetaminophen and children’s language development at 30 months – European Psychiatry (link to abstract – $ for full-text)

Commentaries: Is acetaminophen really safe in pregnancy? – Medical News Today (free) AND Acetaminophen Use During Pregnancy Associated With Elevated Rate of Language Delay in Girls, Mount Sinai Researchers Find – Mount Sinai Health System, via NewsWise (free)

7 – Adherence to Mediterranean Diet Reduces Incident Frailty Risk: Systematic Review and Meta-Analysis – Journal of the American Geriatrics Society (link to abstract – $ for full-text)

Commentaries: Mediterranean diet may help protect older adults from becoming frail – Wiley, via ScienceDaily (free) AND Mediterranean Diet May Lessen Frailty Risk in Older Adults – Medscape (free registration required)

8 – A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED) – Nutritional Neuroscience (free)

Commentaries: Mediterranean Diet Improves Mental Health, Study Finds – Mad in America (free) AND Mediterranean Diet Improves Depression – Mescape (free registration required)

9 – Cardiovascular Risk Factors After Adolescent Bariatric Surgery – Pediatrics (free)

Commentary: Bariatric Surgery Helps Teens With Severe Obesity Reduce Heart Disease Risk – NPR (free) AND Teens show decreased risk for heart disease later in life after bariatric surgery – Nationwide Children’s Hospital, via ScienceDaily (free)