Rheumatology | Page 9 of 37 | Links Medicus Content Curation & Alerts in Medicine

Management of interstitial lung disease (ILD) in myositis syndromes: a practical guide for clinicians.

19 Jul, 2022 | 13:13h | UTC

Management of interstitial lung disease (ILD) in myositis syndromes: a practical guide for clinicians – Best Practice & Research Clinical Rheumatology

RCT | Treat-to-target dose reduction and withdrawal strategy of TNF inhibitors in psoriatic arthritis and axial spondyloarthritis.

19 Jul, 2022 | 13:06h | UTC

Treat-to-target dose reduction and withdrawal strategy of TNF inhibitors in psoriatic arthritis and axial spondyloarthritis: a randomised controlled non-inferiority trial – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentary: TNF inhibitor tapered T2T strategy feasible in PsA and axSpA – medwireNews

Commentary on Twitter

Treat-to-target (#T2T) tapering strategy is an effective and safe alternative to a T2T full dose continuation strategy in patients with #psoriatic #arthritis and axial #spondyloarthritis with stable low disease activity using TNF inhibitorshttps://t.co/YhurbawiTm pic.twitter.com/1jj4zuYkPf

— Annals of the Rheumatic Diseases (@eular_ARD) June 18, 2022

M-A of RCTs | Efficacy of corticosteroids for hand osteoarthritis.

18 Jul, 2022 | 11:07h | UTC

Efficacy of corticosteroids for hand osteoarthritis – a systematic review and meta-analysis of randomized controlled trials – BMC Musculoskeletal Disorders

Review | The current role and future directions of imaging in failed back surgery syndrome patients.

18 Jul, 2022 | 10:46h | UTC

The current role and future directions of imaging in failed back surgery syndrome patients: an educational review – Insights into Imaging

RCT | Deucravacitinib vs. placebo vs. apremilast in moderate to severe plaque psoriasis.

15 Jul, 2022 | 12:26h | UTC

Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: efficacy and safety results from the 52-week, randomized, double-blinded, placebo-controlled phase 3 POETYK PSO-1 trial – Journal of the American Academy of Dermatology (link to abstract – $ for full-text)

One-year safety and efficacy of Tapinarof cream for the treatment of plaque psoriasis.

15 Jul, 2022 | 12:28h | UTC

One-Year Safety and Efficacy of Tapinarof Cream for the Treatment of Plaque Psoriasis: Results from the PSOARING 3 Trial – Journal of the American Academy of Dermatology

News Release: Tapinarof Effective for Longer-Term Treatment of Plaque Psoriasis – HealthDay

RCT | Effect of ultrasonography-guided corticosteroid injection vs. placebo added to exercise therapy for Achilles tendinopathy.

14 Jul, 2022 | 12:18h | UTC

Effect of Ultrasonography-Guided Corticosteroid Injection vs Placebo Added to Exercise Therapy for Achilles Tendinopathy: A Randomized Clinical Trial – JAMA Network Open

Commentary: Trial Backs Steroid Shots for Stubborn Achilles Tendon Pain — Corticosteroid bests placebo when combined with resistance exercise therapy – MedPage Today (free registration required)

Commentary on Twitter

In this RCT, corticosteroid injections + exercise therapy was more effective for patients with long-standing Achilles tendinopathy compared to placebo injections + exercise therapy. https://t.co/nkTH0OYL4a

— JAMA Network Open (@JAMANetworkOpen) July 11, 2022

Long-term follow up of a RCT | Physical therapy noninferior to early arthroscopic partial meniscectomy in patients with degenerative meniscal tears.

12 Jul, 2022 | 12:57h | UTC

Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial – JAMA Network Open

Original Study: Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears: The ESCAPE Randomized Clinical Trial – JAMA

RCT | Leflunomide vs. azathioprine for maintenance therapy of lupus nephritis.

12 Jul, 2022 | 12:51h | UTC

Leflunomide versus azathioprine for maintenance therapy of lupus nephritis: a prospective, multicentre, randomised trial and long-term follow-up – Annals of Rheumatic Diseases

Commentary on Twitter

🆕🔥Leflunomide versus azathioprine for maintenance therapy of lupus nephritis
🫘LEF=AZR in maintenance for SLE-LN
🫘Induction with NIH-CYC
🫘Chinese seem to love Lefno
🫘Generalisability difficult
Would have loved an MMF vs LEF#Rheumtwitter #Nephtwitter https://t.co/N2gTYISibM pic.twitter.com/nlP2LkSu8c

— EnvisionRheumat (@ERheumat) July 5, 2022

Under a http://creativecommons.org/licenses/by-nc/4.0/ license

Review | The promise of precision medicine in rheumatology.

12 Jul, 2022 | 12:38h | UTC

The promise of precision medicine in rheumatology – Nature Reviews Rheumatology

Commentary on Twitter

A Review in @NatureMedicine discusses recent efforts to dissect cellular and molecular heterogeneity across multiple systemic autoimmune rheumatic diseases and future directions for implementing stratification approaches for SARD treatment. https://t.co/5EGTkQjasR pic.twitter.com/NAgbnyU96O

— Nature Portfolio (@NaturePortfolio) July 8, 2022

M-A | Factors correlated with physical function 1 year after total knee arthroplasty in patients with knee osteoarthritis.

12 Jul, 2022 | 12:24h | UTC

Commentary on Twitter

This meta-analysis of 20 prospective cohort studies (11,317 patients) found associations between presurgical BMI, physical function, and osteoarthritis severity and physical function after total knee arthroplasty (TKA). https://t.co/tQf7HytTEW

— JAMA Network Open (@JAMANetworkOpen) July 11, 2022

M-A | Little benefit from viscosupplementation in knee osteoarthritis.

11 Jul, 2022 | 12:39h | UTC

Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis – The BMJ

News Release: Scant evidence to recommend use of hyaluronic acid injections for knee osteoarthritis – BMJ Newsroom

Commentary: Common injections don’t help knee osteoarthritis more than placebo, large data review finds – STAT

Commentary on Twitter

New research finds that injections of hyaluronic acid to treat knee osteoarthritis make almost no difference to pain and might raise risk of adverse events https://t.co/G80BHoOgl3

— The BMJ (@bmj_latest) July 7, 2022

2022 ACR Guideline for the perioperative management of antirheumatic medication in patients with rheumatic diseases undergoing elective total hip or total knee arthroplasty.

11 Jul, 2022 | 12:29h | UTC

2022 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty – Arthritis Care & Research (PDF)

Consensus Paper | Cardiovascular magnetic resonance in autoimmune rheumatic diseases.

11 Jul, 2022 | 12:26h | UTC

Cardiovascular magnetic resonance in autoimmune rheumatic diseases: a clinical consensus document by the European Association of Cardiovascular Imaging – European Heart Journal – Cardiovascular Imaging

RCT | Ustekinumab does not improve outcomes in patients with systemic lupus erythematosus.

8 Jul, 2022 | 11:39h | UTC

Phase 3, multicentre, randomised, placebo-controlled study evaluating the efficacy and safety of ustekinumab in patients with systemic lupus erythematosus – Annals of Rheumatic Diseases

RCT | Efficacy and safety of upadacitinib for active ankylosing spondylitis refractory to biological therapy.

7 Jul, 2022 | 12:44h | UTC

Efficacy and safety of upadacitinib for active ankylosing spondylitis refractory to biological therapy: a double-blind, randomised, placebo-controlled phase 3 trial – Annals of Rheumatic Diseases

Commentary on Twitter

SELECT-AXIS 2 trial – patients with #AS and inadequate response to #bDMARDs. #RCT of upadacitinb vs placebo 14 weeks:
Improved signs and symptoms of active AS and was well tolerated for 14 weeks of treatment in bDMARD-IR patients!https://t.co/Z7fuxiXMDb pic.twitter.com/kGZX9AsaVE

— Annals of the Rheumatic Diseases (@eular_ARD) July 5, 2022